{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T09:00:00Z","timestamp":1770454800413,"version":"3.49.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"S9","license":[{"start":{"date-parts":[[2013,6,1]],"date-time":"2013-06-01T00:00:00Z","timestamp":1370044800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Bioinformatics"],"published-print":{"date-parts":[[2013,6]]},"DOI":"10.1186\/1471-2105-14-s9-s6","type":"journal-article","created":{"date-parts":[[2019,1,22]],"date-time":"2019-01-22T09:44:41Z","timestamp":1548150281000},"source":"Crossref","is-referenced-by-count":17,"title":["MGC: a metagenomic gene caller"],"prefix":"10.1186","volume":"14","author":[{"given":"Achraf","family":"El Allali","sequence":"first","affiliation":[]},{"given":"John R","family":"Rose","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2013,6,28]]},"reference":[{"issue":"Web Server","key":"5954_CR1","doi-asserted-by":"publisher","first-page":"W101","DOI":"10.1093\/nar\/gkp327","volume":"37","author":"KJ Hoff","year":"2009","unstructured":"Hoff KJ, Lingner T, Meinicke P, Tech M: Orphelia: predicting genes in metagenomic sequencing reads. Nucleic acids research. 2009, 37 (Web Server): W101-5. 10.1093\/nar\/gkp327. [\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19429689\n                    \n                  ]","journal-title":"Nucleic acids research"},{"key":"5954_CR2","first-page":"411","volume-title":"Engineering and Technology","author":"AE Allali","year":"2010","unstructured":"Allali AE, Rose JR: MIM: A Species Independent Approach for Classifying Coding and Non-Coding DNA Sequences in Bacterial and Archaeal Genomes. Engineering and Technology. 2010, 411-418."},{"issue":"2","key":"5954_CR3","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1101\/gr.7088808","volume":"18","author":"MJ Chaisson","year":"2008","unstructured":"Chaisson MJ, Pevzner PA: Short read fragment assembly of bacterial genomes. Genome Research. 2008, 18 (2): 324-330. 10.1101\/gr.7088808.","journal-title":"Genome Research"},{"issue":"5","key":"5954_CR4","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1101\/gr.7337908","volume":"18","author":"J Butler","year":"2008","unstructured":"Butler J, MacCallum I, Kleber M, Shlyakhter IA, Belmonte MK, Lander ES, Nusbaum C, Jaffe DB: ALLPATHS: De novo assembly of whole-genome shotgun microreads. Genome Research. 2008, 18 (5): 810-820. 10.1101\/gr.7337908. [\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18340039\n                    \n                  ]","journal-title":"Genome Research"},{"issue":"19","key":"5954_CR5","doi-asserted-by":"publisher","first-page":"5623","DOI":"10.1093\/nar\/gkl723","volume":"34","author":"H Noguchi","year":"2006","unstructured":"Noguchi H, Park J, Takagi T: MetaGene: prokaryotic gene finding from environmental genome shotgun sequences. Nucleic Acids Research. 2006, 34 (19): 5623-5630. 10.1093\/nar\/gkl723. [\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17028096\n                    \n                  ]","journal-title":"Nucleic Acids Research"},{"key":"5954_CR6","volume-title":"Current protocols in bioinformatics editoral board Andreas D Baxevanis et al","author":"M Borodovsky","year":"2003","unstructured":"Borodovsky M, Mills R, Besemer J, Lomsadze A: Prokaryotic gene prediction using GeneMark and GeneMark.hmm. Current protocols in bioinformatics editoral board Andreas D Baxevanis et al. 2003, Chapter 4:Unit4.5, [\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18428700\n                    \n                  ]"},{"issue":"20","key":"5954_CR7","doi-asserted-by":"publisher","first-page":"e191","DOI":"10.1093\/nar\/gkq747","volume":"38","author":"M Rho","year":"2010","unstructured":"Rho M, Tang H, Ye Y: FragGeneScan: predicting genes in short and error-prone reads. Nucleic Acids Research. 2010, 38 (20): e191-10.1093\/nar\/gkq747.","journal-title":"Nucleic Acids Research"},{"key":"5954_CR8","first-page":"90","volume-title":"Proc 12th International Conference on Machine Learning","author":"PK Chan","year":"1995","unstructured":"Chan PK, Stolfo SJ: A comparative evaluation of voting and meta-learning on partitioned data. Proc 12th International Conference on Machine Learning. 1995, Morgan Kaufmann, 90-98. [\n                    http:\/\/citeseerx.ist.psu.edu\/viewdoc\/summary?doi=10.1.1.47.7713\n                    \n                  ]"},{"issue":"11","key":"5954_CR9","doi-asserted-by":"publisher","first-page":"1581","DOI":"10.1093\/oxfordjournals.molbev.a026257","volume":"17","author":"GA Singer","year":"2000","unstructured":"Singer GA, Hickey DA: Nucleotide bias causes a genomewide bias in the amino acid composition of proteins. Molecular Biology and Evolution. 2000, 17 (11): 1581-1588. 10.1093\/oxfordjournals.molbev.a026257. [\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11070046\n                    \n                  ]","journal-title":"Molecular Biology and Evolution"},{"issue":"3","key":"5954_CR10","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1371\/journal.pone.0017677","volume":"6","author":"J Lightfield","year":"2011","unstructured":"Lightfield J, Fram NR, Ely B: Across Bacterial Phyla, Distantly-Related Genomes with Similar Genomic GC Content Have Similar Patterns of Amino Acid Usage. PLoS ONE. 2011, 6 (3): 12-","journal-title":"PLoS ONE"},{"issue":"3","key":"5954_CR11","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1007\/BF02338829","volume":"43","author":"JL Oliver","year":"1996","unstructured":"Oliver JL, Mar\u00edn A: A relationship between GC content and coding-sequence length. Journal of Molecular Evolution. 1996, 43 (3): 216-223. 10.1007\/BF02338829.","journal-title":"Journal of Molecular Evolution"},{"key":"5954_CR12","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1186\/1756-0500-4-20","volume":"4","author":"K Misawa","year":"2011","unstructured":"Misawa K, Kikuno RF: Relationship between amino acid composition and gene expression in the mouse genome. BMC research notes. 2011, 4: 20-10.1186\/1756-0500-4-20.","journal-title":"BMC research notes"},{"key":"5954_CR13","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1038\/nbt0196-61","volume":"14","author":"MR Wilkins","year":"1996","unstructured":"Wilkins MR, Pasquali C, Appel RD, Ou K, Golaz O, Sanchez JC, Yan JX, Gooley AA, Hughes G, Humphery-Smith I, Williams KL, Hochstrasser DF: From proteins to proteomes: large scale protein identification by two-dimensional electrophoresis and amino acid analysis. Biotechnology NY. 1996, 14: 61-65. 10.1038\/nbt0196-61.","journal-title":"Biotechnology NY"},{"issue":"3","key":"5954_CR14","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1006\/jmbi.1995.0442","volume":"251","author":"U Hobohm","year":"1995","unstructured":"Hobohm U, Sander C: A sequence property approach to searching protein databases. Journal of Molecular Biology. 1995, 251 (3): 390-399. 10.1006\/jmbi.1995.0442.","journal-title":"Journal of Molecular Biology"},{"issue":"2","key":"5954_CR15","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1093\/protein\/4.2.155","volume":"4","author":"K Guruprasad","year":"1990","unstructured":"Guruprasad K, Reddy BV, Pandit MW: Correlation between stability of a protein and its dipeptide composition: a novel approach for predicting in vivo stability of a protein from its primary sequence. Protein Engineering. 1990, 4 (2): 155-161. 10.1093\/protein\/4.2.155.","journal-title":"Protein Engineering"},{"issue":"4","key":"5954_CR16","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1007\/s00239-003-2499-1","volume":"57","author":"R Merkl","year":"2003","unstructured":"Merkl R: A survey of codon and amino acid frequency bias in microbial genomes focusing on translational efficiency. Journal of Molecular Evolution. 2003, 57 (4): 453-466. 10.1007\/s00239-003-2499-1.","journal-title":"Journal of Molecular Evolution"},{"issue":"Database","key":"5954_CR17","doi-asserted-by":"publisher","first-page":"D23","DOI":"10.1093\/nar\/gkh045","volume":"32","author":"DA Benson","year":"2004","unstructured":"Benson DA, Karsch-Mizrachi I, Lipman DJ, Ostell J, Wheeler DL: GenBank: update. Nucleic Acids Research. 2004, 32 (Database): D23-D26. [\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/14681350\n                    \n                  ]","journal-title":"Nucleic Acids Research"},{"key":"5954_CR18","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1186\/1471-2105-9-217","volume":"9","author":"KJ Hoff","year":"2008","unstructured":"Hoff KJ, Tech M, Lingner T, Daniel R, Morgenstern B, Meinicke P: Gene prediction in metagenomic fragments: a large scale machine learning approach. BMC bioinformatics. 2008, 9: 217-10.1186\/1471-2105-9-217. [\n                    http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18442389\n                    \n                  ]","journal-title":"BMC bioinformatics"},{"issue":"3","key":"5954_CR19","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1162\/neco.1992.4.3.448","volume":"4","author":"DJC MacKay","year":"1992","unstructured":"MacKay DJC: A Practical Bayesian Framework for Backpropagation Networks. Neural Computation. 1992, 4 (3): 448-472. 10.1162\/neco.1992.4.3.448. [\n                    http:\/\/www.mitpressjournals.org\/doi\/abs\/10.1162\/neco.1992.4.3.448\n                    \n                  ]","journal-title":"Neural Computation"},{"key":"5954_CR20","volume-title":"NETLAB: algorithms for pattern recognition (Google eBook)","author":"I Nabney","year":"2002","unstructured":"Nabney I: NETLAB: algorithms for pattern recognition (Google eBook). 2002, Springer, [\n                    http:\/\/www.springer.com\/computer\/ai\/book\/978-1-85233-440-6\n                    \n                  ]"},{"key":"5954_CR21","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/2042-5783-2-3","volume":"2","author":"T Thomas","year":"2012","unstructured":"Thomas T, Gilbert J, Meyer F: Metagenomics - a guide from sampling to data analysis. Microbial Informatics and Experimentation. 2012, 2: 3-10.1186\/2042-5783-2-3. [\n                    http:\/\/www.microbialinformaticsj.com\/content\/2\/1\/3\n                    \n                  ]","journal-title":"Microbial Informatics and Experimentation"},{"key":"5954_CR22","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1007\/978-1-4471-0513-8_39","volume-title":"Artificial Neural Networks in Medicine and Biology","author":"JV Hansen","year":"2000","unstructured":"Hansen JV, Krogh A: A general method for combining predictors tested on protein secondary structure prediction. Artificial Neural Networks in Medicine and Biology. 2000, 259-264. [\n                    http:\/\/link.springer.com\/chapter\/10.1007%2F978-1-4471-0513-8_39\n                    \n                  ]"}],"container-title":["BMC Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2105-14-S9-S6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2105-14-S9-S6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2105-14-S9-S6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,22]],"date-time":"2019-01-22T11:13:25Z","timestamp":1548155605000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcbioinformatics.biomedcentral.com\/articles\/10.1186\/1471-2105-14-S9-S6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6]]},"references-count":22,"journal-issue":{"issue":"S9","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["5954"],"URL":"https:\/\/doi.org\/10.1186\/1471-2105-14-s9-s6","relation":{},"ISSN":["1471-2105"],"issn-type":[{"value":"1471-2105","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6]]},"article-number":"S6"}}