{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T19:49:32Z","timestamp":1762458572629,"version":"3.33.0"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2007,7,2]],"date-time":"2007-07-02T00:00:00Z","timestamp":1183334400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Bioinformatics"],"published-print":{"date-parts":[[2007,12]]},"DOI":"10.1186\/1471-2105-8-233","type":"journal-article","created":{"date-parts":[[2007,7,3]],"date-time":"2007-07-03T06:14:21Z","timestamp":1183443261000},"source":"Crossref","is-referenced-by-count":39,"title":["Robust regression for periodicity detection in non-uniformly sampled time-course gene expression data"],"prefix":"10.1186","volume":"8","author":[{"given":"Miika","family":"Ahdesm\u00e4ki","sequence":"first","affiliation":[]},{"given":"Harri","family":"L\u00e4hdesm\u00e4ki","sequence":"additional","affiliation":[]},{"given":"Andrew","family":"Gracey","sequence":"additional","affiliation":[]},{"given":"llya","family":"Shmulevich","sequence":"additional","affiliation":[]},{"given":"Olli","family":"Yli-Harja","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2007,7,2]]},"reference":[{"key":"1605_CR1","unstructured":"Robust regression for periodicity detection in non-uniformly sampled time-course gene expression data. Supplementary website. [ http:\/\/www.cs.tut.fi\/sgn\/csb\/robustregper\/ ]"},{"key":"1605_CR2","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1126\/science.270.5235.467","volume":"270","author":"M Schena","year":"1995","unstructured":"Schena M, Shalon D, Davis R, Brown P: Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray. Science. 1995, 270: 467-470.","journal-title":"Science"},{"key":"1605_CR3","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1093\/bioinformatics\/btg364","volume":"20","author":"S Wichert","year":"2004","unstructured":"Wichert S, Fokianos K, Strimmer K: Identifying periodically expressed transcripts in microarray time series data. Bioinformatics. 2004, 20: 5-20.","journal-title":"Bioinformatics"},{"key":"1605_CR4","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1186\/1471-2105-6-286","volume":"6","author":"J Chen","year":"2005","unstructured":"Chen J: Identification of significant genes in microarray gene expression data. BMC Bioinformatics. 2005, 6: 286-","journal-title":"BMC Bioinformatics"},{"key":"1605_CR5","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1186\/1471-2105-6-117","volume":"6","author":"M Ahdesm\u00e4ki","year":"2005","unstructured":"Ahdesm\u00e4ki M, L\u00e4hdfdm\u00e4ki H, Pearson R, Huttenen H, Yli-Harja O: Robust detection of periodic sequences in biological time series. BMC Bioinformatics. 2005, 6: 117-","journal-title":"BMC Bioinformatics"},{"key":"1605_CR6","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1098\/rspa.1929.0151","volume":"125","author":"R Fisher","year":"1929","unstructured":"Fisher R: Test of Significance in Harmonic Analysis. Proceedings of the Royal Society of London. 1929, 125: 54-59.","journal-title":"Proceedings of the Royal Society of London"},{"key":"1605_CR7","volume-title":"Bioinformatics","author":"E Glynn","year":"2005","unstructured":"Glynn E, Chen J, Mushegian A: Detection periodic pattersns in unevenly spaced gene expression time serises using Lomb-scargle periodogram. Bioinformatics. 2005"},{"key":"1605_CR8","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4419-0320-4","volume-title":"Time series: Theory and Methods","author":"P Brockwell","year":"1991","unstructured":"Brockwell P, Davis R: Time series: Theory and Methods. 1991, Springer-verlag, New York, 2","edition":"2"},{"key":"1605_CR9","doi-asserted-by":"publisher","first-page":"1164","DOI":"10.1093\/bioinformatics\/bti093","volume":"21","author":"U de Lichtenberg","year":"2004","unstructured":"de Lichtenberg U, Jensen L, Fausb\u00f8 ll A, Jensen T, Bork P, Brunak S: Comparisson of computational methods for the identification of cell cycle regulated genes. Bioinformatics. 2004, 21: 1164-1171.","journal-title":"Bioinformatics"},{"key":"1605_CR10","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1093\/bioinformatics\/btg017","volume":"19","author":"D Johansson","year":"2003","unstructured":"Johansson D, Lindgren P, Berglund A: A multivariate approach applied to microarray data for identification of genes with cell cycle-coupled transcription. Bioinformatics. 2003, 19: 467-473.","journal-title":"Bioinformatics"},{"key":"1605_CR11","doi-asserted-by":"publisher","first-page":"7240","DOI":"10.1073\/pnas.0402285101","volume":"101","author":"D Liu","year":"2004","unstructured":"Liu D, Umbach D, Peddada S, Li L, Crockett P, Weinberg C: A random-periods model for expression of cell-cycle genes. Proceedings of the National Academy of Sciences of the USA. 2004, 101: 7240-7245.","journal-title":"Proceedings of the National Academy of Sciences of the USA"},{"key":"1605_CR12","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1093\/nar\/gkh205","volume":"32","author":"X Lu","year":"2004","unstructured":"Lu X, Zhang W, Qin Z, Kwast K, Liu J: Statistical resynchronization and Bayesian detection of periodically expressed genes. Nucleic Acids Research. 2004, 32: 447-455.","journal-title":"Nucleic Acids Research"},{"key":"1605_CR13","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1093\/bioinformatics\/btg413","volume":"20","author":"Y Luan","year":"2004","unstructured":"Luan Y, Li H: Model-based methods for identifying periodically expressed genes based on time course microarray gene expression data. Bioinformatics. 2004, 20: 332-339.","journal-title":"Bioinformatics"},{"key":"1605_CR14","doi-asserted-by":"publisher","first-page":"5631","DOI":"10.1073\/pnas.101013198","volume":"98","author":"L Zhao","year":"2001","unstructured":"Zhao L, Prentice R, Breeden L: Statistical modeling of large microarray data sets to identify stimulusresponse profiles. Proceedings of the National Academy of Sciences of the USA. 2001, 98: 5631-5636.","journal-title":"Proceedings of the National Academy of Sciences of the USA"},{"key":"1605_CR15","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1186\/1471-2105-7-63","volume":"7","author":"C Andersson","year":"2006","unstructured":"Andersson C, Isaksson A, Gustafsson M: Bayesian detection of periodic mRNA time profiles without use of training examples. BMC Bioinformatics. 2006, 7: 63-","journal-title":"BMC Bioinformatics"},{"key":"1605_CR16","volume-title":"Proceedings of the 22nd International Conference on Machine Learning: Bonn, Germany","author":"R Singh","year":"2005","unstructured":"Singh R, Palmer N, Gifford D, Berger B, Bar-Joseph Z: Active Learning for Sampling in Time-Series Experiments With Application to Gene Expression Analysis. Proceedings of the 22nd International Conference on Machine Learning: Bonn, Germany. 2005"},{"key":"1605_CR17","first-page":"107","volume":"406","author":"A Schwarzenberg-Czerny","year":"1996","unstructured":"Schwarzenberg-Czerny A: Fast and statistically optimal period search in uneven sampled observations. The Astrophysical Journal. 1996, 406: 107-110.","journal-title":"The Astrophysical Journal"},{"key":"1605_CR18","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1086\/304206","volume":"483","author":"P Frick","year":"1997","unstructured":"Frick P, Baliunas S, Galyagin D, Sokoloff D, Soon W: Wavelet Analysis of Stellar Chromospheric Activity Variations. The Astrophysical Journal. 1997, 483: 426-434.","journal-title":"The Astrophysical Journal"},{"key":"1605_CR19","doi-asserted-by":"publisher","first-page":"698","DOI":"10.1109\/10.678605","volume":"45","author":"P Laguna","year":"1998","unstructured":"Laguna P, Moody G, Mark R: Power spectral density of unevenly sampled data by least-squareanalysis: performance and application to heart rate signals. IEEE Transactions on Biomedical Engineering. 1998, 45: 698-715.","journal-title":"IEEE Transactions on Biomedical Engineering"},{"key":"1605_CR20","first-page":"2257","volume":"4","author":"M Rasile","year":"1997","unstructured":"Rasile M, Tagliaferri R, Milano L, Longo G: Neural networks for periodicity analysis of unevenly spaced data. International Conference on Neural Networks. 1997, 4: 2257-2262.","journal-title":"International Conference on Neural Networks"},{"key":"1605_CR21","doi-asserted-by":"publisher","first-page":"1425","DOI":"10.1109\/ISCAS.2005.1464865","volume":"2","author":"A Tarczynski","year":"2005","unstructured":"Tarczynski A, Dongdong Q: Optimal periodic sampling sequences for nearly-alias-free digital signal processing. IEEE International Symposium, on Circuits and Systems, 2005. 2005, 2: 1425-1428.","journal-title":"IEEE International Symposium, on Circuits and Systems, 2005"},{"key":"1605_CR22","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1109\/ISIE.1996.548418","volume":"1","author":"A Tarczynski","year":"1996","unstructured":"Tarczynski A, Bland D, Laakso T: Spectrum estimation of non-uniformly sampled signals. Proceedings of the IEEE International Symposium on Industrial Electronics. 1996, 1: 196-200.","journal-title":"Proceedings of the IEEE International Symposium on Industrial Electronics"},{"key":"1605_CR23","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4684-9399-3","volume-title":"Bayesian Spectrum, Analysis and Parameter Estimation","author":"G Bretthorst","year":"1988","unstructured":"Bretthorst G: Bayesian Spectrum, Analysis and Parameter Estimation. Edited by: 1. 1988, Springcr-Vcrlag, Berlin Heidelberg"},{"key":"1605_CR24","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1109\/97.473649","volume":"2","author":"P Djuri\u0107","year":"1995","unstructured":"Djuri\u0107 P, Li HT: Bayesian Spectrum Estimation of Harmonic Signals. IEEE Signal Processing Letters. 1995, 2: 213-215.","journal-title":"IEEE Signal Processing Letters"},{"key":"1605_CR25","first-page":"1473","volume":"2","author":"Y Qi","year":"2002","unstructured":"Qi Y, Minka T, Picard R: Bayesian Spectrum Estimation of Unevenly Sampled Nonstationary Data. IEEE International Conference on Acoustics, Speech, and Signal Processing. 2002, 2: 1473-1476.","journal-title":"IEEE International Conference on Acoustics, Speech, and Signal Processing"},{"key":"1605_CR26","volume-title":"UW Biostatistics Working Paper Series","author":"C Zhou","year":"2005","unstructured":"Zhou C, Wakefield J, Breeden L: Bayesian Analysis of Cell-Cycle Gene Expression Data. UW Biostatistics Working Paper Series. 2005, 276:"},{"key":"1605_CR27","volume-title":"Robust statistics: The Approach Based on Influence Function","author":"F Hampel","year":"1986","unstructured":"Hampel F, Ronchetti E, Rousseeuw P, Stahel W: Robust statistics: The Approach Based on Influence Function. 1986, Wiley edition"},{"key":"1605_CR28","doi-asserted-by":"publisher","DOI":"10.1002\/0471725382","volume-title":"Robust Regression and Outlier Detection","author":"P Rousseeuw","year":"1987","unstructured":"Rousseeuw P, Leroy A: Robust Regression and Outlier Detection. 1987, Wiley"},{"key":"1605_CR29","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1198\/004017004000000329","volume":"46","author":"P Rousseeuw","year":"2004","unstructured":"Rousseeuw P, Van Aelst S, Van Driessen K, Gull\u00f3 J: Robust Multivariate Regression. Technometrics. 2004, 46: 293-305.","journal-title":"Technometrics"},{"key":"1605_CR30","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1111\/j.2517-6161.1993.tb01947.x","volume":"55","author":"L Tatum","year":"1993","unstructured":"Tatum L, Hurvich C: High Breakdown Methods of Time Series Analysis. Journal of the Royal Statistical, Society. Series B (Methodological). 1993, 55: 881-896.","journal-title":"Journal of the Royal Statistical, Society. Series B (Methodological)"},{"key":"1605_CR31","volume-title":"Pattern Classification","author":"R Duda","year":"2001","unstructured":"Duda R, Hart P, Stork D: Pattern Classification. 2001, Wiley, 2","edition":"2"},{"key":"1605_CR32","unstructured":"ArrayExpress. [ http:\/\/www.ebi.ac.uk\/arrayexpress\/ ]"},{"key":"1605_CR33","first-page":"139","volume-title":"New Directions in Statistical Data Analysis and Robustness","author":"P Huber","year":"1993","unstructured":"Huber P: Projection pursuit and robustness. New Directions in Statistical Data Analysis and Robustness. Edited by: Morgenthaler S, Ronchetti E, Stahel W, Basel. 1993, Boston: Birkh\u00e4user Verlag, 139-146."},{"key":"1605_CR34","doi-asserted-by":"publisher","DOI":"10.1137\/1.9780898717884","volume-title":"Mining Imperfect Data: dealing with contamination and incomplete records","author":"R Pearson","year":"2005","unstructured":"Pearson R: Mining Imperfect Data: dealing with contamination and incomplete records. 2005, Siam"},{"key":"1605_CR35","doi-asserted-by":"publisher","first-page":"15545","DOI":"10.1073\/pnas.0506580102","volume":"102","author":"A Subramanian","year":"2005","unstructured":"Subramanian A, Tamayo P, Mootha V, Mukherjee S, Ebert B, Gillette M, Paulovich A, Pomeroy S, Golub T, Lander E, Mesirov J: Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proceedings of the National Academy of Sciences of the USA. 2005, 102: 15545-15550.","journal-title":"Proceedings of the National Academy of Sciences of the USA"},{"key":"1605_CR36","volume-title":"LADOAN10: 10\u201313 July 2000; Lisbon","author":"O Kaleva","year":"2000","unstructured":"Kaleva O, Ihalainen H, Saarenrinne P: A wavelet based method for the estimation of the power spectrum from irregularly sampled data. LADOAN10: 10\u201313 July 2000; Lisbon. 2000"},{"key":"1605_CR37","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1007\/s101420000027","volume":"1","author":"R Klevecz","year":"2000","unstructured":"Klevecz R: Dynamic architecture of the yeast cell cycle uncovered by wavelet decomposition of expression microarray data. Fund Integr Genomics. 2000, 1: 186-192.","journal-title":"Fund Integr Genomics"},{"key":"1605_CR38","volume-title":"Spectral Analysis and Time Series","author":"M Priestley","year":"1981","unstructured":"Priestley M: Spectral Analysis and Time Series. 1981, Academic Press, London"},{"key":"1605_CR39","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1086\/160554","volume":"263","author":"J Scargle","year":"1982","unstructured":"Scargle J: Studies in astronomical time series analysis. II. Statistical aspects of spectral analysis of unevenly spaced data. The Astrophysical Journal. 1982, 263: 835-853.","journal-title":"The Astrophysical Journal"},{"key":"1605_CR40","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","volume":"57","author":"Y Benjamini","year":"1995","unstructured":"Benjamini Y, Hochberg Y: Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc, Ser B, Methodol. 1995, 57: 289-300.","journal-title":"J R Stat Soc, Ser B, Methodol"},{"key":"1605_CR41","doi-asserted-by":"publisher","DOI":"10.1002\/0471725250","volume-title":"Robust Statistics","author":"P Huber","year":"1981","unstructured":"Huber P: Robust Statistics. 1981, Wiley"},{"key":"1605_CR42","volume-title":"Statistics Toolbox. User's Guide","author":"The MathWorks, Inc","year":"2005","unstructured":"The MathWorks, Inc: Statistics Toolbox. User's Guide. 2005, The MathWorks, Inc, 5","edition":"5"},{"key":"1605_CR43","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1007\/978-3-642-58250-9_27","volume-title":"Data Analysis: Scientific Modeling and Practical Application","author":"P Rousseeuw","year":"2000","unstructured":"Rousseeuw P, Van Driessen K: An algorithm for positive-breakdown methods based on concentration steps. Data Analysis: Scientific Modeling and Practical Application. Edited by: Gaul W, Opitz O, Schader M. 2000, New York: Springer-Verlag, 335-346."},{"key":"1605_CR44","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1080\/00401706.1999.10485670","volume":"41","author":"P Rousseeuw","year":"1999","unstructured":"Rousseeuw P, Van Driessen K: A Fast Algorithm for the Minimum Covariance Determinant Estimator. Technometrics. 1999, 41: 212-223.","journal-title":"Technometrics"},{"key":"1605_CR45","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1076\/brhm.32.3.341.1340","volume":"32","author":"M Schimmel","year":"2001","unstructured":"Schimmel M: Emphasizing Difficulties in the Detection of Rhythms with Lomb-Scargle Periodograms. Biological Rhythm Research. 2001, 32: 341-346.","journal-title":"Biological Rhythm Research"},{"key":"1605_CR46","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1093\/bioinformatics\/bth499","volume":"21","author":"H Kim","year":"2005","unstructured":"Kim H, Golub G, Park H: Missing value estimation for DNA microarray gene expression data: local least squares imputation. Bioinformatics. 2005, 21: 187-198.","journal-title":"Bioinformatics"}],"container-title":["BMC Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2105-8-233.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2105-8-233\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2105-8-233.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,18]],"date-time":"2025-01-18T03:39:37Z","timestamp":1737171577000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcbioinformatics.biomedcentral.com\/articles\/10.1186\/1471-2105-8-233"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7,2]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,12]]}},"alternative-id":["1605"],"URL":"https:\/\/doi.org\/10.1186\/1471-2105-8-233","relation":{},"ISSN":["1471-2105"],"issn-type":[{"type":"electronic","value":"1471-2105"}],"subject":[],"published":{"date-parts":[[2007,7,2]]},"article-number":"233"}}