{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T16:00:10Z","timestamp":1757779210308,"version":"3.33.0"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"S1","license":[{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Bioinformatics"],"published-print":{"date-parts":[[2008,2]]},"DOI":"10.1186\/1471-2105-9-s1-s19","type":"journal-article","created":{"date-parts":[[2008,2,13]],"date-time":"2008-02-13T19:14:01Z","timestamp":1202930041000},"source":"Crossref","is-referenced-by-count":20,"title":["Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen proteomes"],"prefix":"10.1186","volume":"9","author":[{"given":"Guang Lan","family":"Zhang","sequence":"first","affiliation":[]},{"given":"Asif M","family":"Khan","sequence":"additional","affiliation":[]},{"given":"Kellathur N","family":"Srinivasan","sequence":"additional","affiliation":[]},{"given":"AT","family":"Heiny","sequence":"additional","affiliation":[]},{"given":"KX","family":"Lee","sequence":"additional","affiliation":[]},{"given":"Chee Keong","family":"Kwoh","sequence":"additional","affiliation":[]},{"given":"J Thomas","family":"August","sequence":"additional","affiliation":[]},{"given":"Vladimir","family":"Brusic","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2008,2,13]]},"reference":[{"key":"2563_CR1","volume-title":"Immunobiology","author":"CAJ Janeway","year":"1999","unstructured":"Janeway CAJ, Travers P, Walport M, Capra JD: Immunobiology. London: Elsevier Science; 1999."},{"key":"2563_CR2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1006\/excr.2001.5402","volume":"272","author":"AW Hudson","year":"2002","unstructured":"Hudson AW, Ploegh HL: The cell biology of antigen presentation. Exp Cell Res 2002, 272: 1\u20137. 10.1006\/excr.2001.5402","journal-title":"Exp Cell Res"},{"issue":"3","key":"2563_CR3","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1046\/j.1440-1711.2002.01076.x","volume":"80","author":"IA Doytchinova","year":"2002","unstructured":"Doytchinova IA, Flower DR: Quantitative approaches to computational vaccinology. Immunol Cell Biol 2002, 80(3):270\u2013279. 10.1046\/j.1440-1711.2002.01076.x","journal-title":"Immunol Cell Biol"},{"key":"2563_CR4","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/S1525-1578(10)60658-7","volume":"3","author":"TM Williams","year":"2001","unstructured":"Williams TM: Human leukocyte antigen gene polymorphism and the histocompatibility laboratory. J Mol Diagn 2001, 3: 98\u2013104.","journal-title":"J Mol Diagn"},{"key":"2563_CR5","first-page":"313","volume":"6","author":"V Brusic","year":"1999","unstructured":"Brusic V, Zeleznikow J: Computational binding assays of antigenic peptides. Lett Pept Sci 1999, 6: 313\u2013324.","journal-title":"Lett Pept Sci"},{"issue":"4","key":"2563_CR6","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1016\/j.ymeth.2004.06.006","volume":"34","author":"V Brusic","year":"2004","unstructured":"Brusic V, Bajic VB, Petrovsky N: Computational methods for prediction of T-cell epitopes \u2013 a framework for modelling, testing, and applications. Methods 2004, 34(4):436\u2013443. 10.1016\/j.ymeth.2004.06.006","journal-title":"Methods"},{"issue":"4","key":"2563_CR7","doi-asserted-by":"publisher","first-page":"339","DOI":"10.4065\/77.4.339","volume":"77","author":"C Buteau","year":"2002","unstructured":"Buteau C, Markovic SN, Celis E: Challenges in the development of effective peptide vaccines for cancer. Mayo Clin Proc 2002, 77(4):339\u2013349.","journal-title":"Mayo Clin Proc"},{"issue":"1","key":"2563_CR8","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1038\/nm1461","volume":"13","author":"W Fischer","year":"2007","unstructured":"Fischer W, Perkins S, Theiler J, Bhattacharya T, Yusim K, Funkhouser R, Kuiken C, Haynes B, Letvin NL, Walker BD, et al.: Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants. Nat Med 2007, 13(1):100\u2013106. 10.1038\/nm1461","journal-title":"Nat Med"},{"issue":"Suppl 5","key":"2563_CR9","doi-asserted-by":"publisher","first-page":"S4","DOI":"10.1186\/1471-2105-7-S5-S4","volume":"7","author":"AM Khan","year":"2006","unstructured":"Khan AM, Heiny A, Lee KX, Srinivasan K, Tan TW, August JT, Brusic V: Large-scale analysis of antigenic diversity of T-cell epitopes in dengue virus. BMC Bioinformatics 2006, 7(Suppl 5):S4. 10.1186\/1471-2105-7-S5-S4","journal-title":"BMC Bioinformatics"},{"key":"2563_CR10","doi-asserted-by":"crossref","unstructured":"Reche PA, Reinherz EL: PEPVAC: a web server for multi-epitope vaccine development based on the prediction of supertypic MHC ligands. Nucleic Acids Res 2005, (33 Web Server):W138\u2013142. 10.1093\/nar\/gki357","DOI":"10.1093\/nar\/gki357"},{"issue":"1","key":"2563_CR11","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.virol.2005.11.042","volume":"347","author":"V Gupta","year":"2006","unstructured":"Gupta V, Tabiin T, Sun K, Chandrasekaran A, Anwar A, Yang K, Chikhlikar P, Salmon J, Brusic V, Marques E, et al.: SARS coronavirus nucleocapsid immunodominant T-cell epitope cluster is common to both exogenous recombinant and endogenous DNA-encoded immunogens. Virology 2006, 347(1):127\u2013139. 10.1016\/j.virol.2005.11.042","journal-title":"Virology"},{"issue":"3","key":"2563_CR12","doi-asserted-by":"publisher","first-page":"876","DOI":"10.1172\/JCI115389","volume":"88","author":"JA Berzofsky","year":"1991","unstructured":"Berzofsky JA, Pendleton CD, Clerici M, Ahlers J, Lucey DR, Putney SD, Shearer GM: Construction of peptides encompassing multideterminant clusters of human immunodeficiency virus envelope to induce in vitro T cell responses in mice and humans of multiple MHC types. J Clin Invest 1991, 88(3):876\u2013884.","journal-title":"J Clin Invest"},{"issue":"8","key":"2563_CR13","doi-asserted-by":"publisher","first-page":"4587","DOI":"10.1073\/pnas.071063898","volume":"98","author":"S Surman","year":"2001","unstructured":"Surman S, Lockey TD, Slobod KS, Jones B, Riberdy JM, White SW, Doherty PC, Hurwitz JL: Localization of CD4+ T cell epitope hotspots to exposed strands of HIV envelope glycoprotein suggests structural influences on antigen processing. Proc Natl Acad Sci USA 2001, 98(8):4587\u20134592. 10.1073\/pnas.071063898","journal-title":"Proc Natl Acad Sci USA"},{"issue":"8","key":"2563_CR14","doi-asserted-by":"publisher","first-page":"4140","DOI":"10.4049\/jimmunol.171.8.4140","volume":"171","author":"SA Brown","year":"2003","unstructured":"Brown SA, Stambas J, Zhan X, Slobod KS, Coleclough C, Zirkel A, Surman S, White SW, Doherty PC, Hurwitz JL: Clustering of Th cell epitopes on exposed regions of HIV envelope despite defects in antibody activity. J Immunol 2003, 171(8):4140\u20134148.","journal-title":"J Immunol"},{"issue":"4","key":"2563_CR15","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/S0952-7915(00)00237-5","volume":"13","author":"SK Kim","year":"2001","unstructured":"Kim SK, DeMars R: Epitope clusters in the major outer membrane protein of Chlamydia trachomatis. Curr Opin Immunol 2001, 13(4):429\u2013436. 10.1016\/S0952-7915(00)00237-5","journal-title":"Curr Opin Immunol"},{"issue":"3\u20134","key":"2563_CR16","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1007\/s002510050594","volume":"50","author":"A Sette","year":"1999","unstructured":"Sette A, Sidney J: Nine major HLA class I supertypes account for the vast preponderance of HLA-A and -B polymorphism. Immunogenetics 1999, 50(3\u20134):201\u2013212. 10.1007\/s002510050594","journal-title":"Immunogenetics"},{"key":"2563_CR17","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/1745-7580-3-5","volume":"3","author":"B Trost","year":"2007","unstructured":"Trost B, Bickis M, Kusalik A: Strength in numbers: achieving greater accuracy in MHC-I binding prediction by combining the results from multiple prediction tools. Immunome Res 2007, 3: 5. 10.1186\/1745-7580-3-5","journal-title":"Immunome Res"},{"issue":"1","key":"2563_CR18","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1007\/s12038-007-0004-5","volume":"32","author":"M Bhasin","year":"2007","unstructured":"Bhasin M, Raghava GP: A hybrid approach for predicting promiscuous MHC class I restricted T cell epitopes. J Biosci 2007, 32(1):31\u201342. 10.1007\/s12038-007-0004-5","journal-title":"J Biosci"},{"issue":"1","key":"2563_CR19","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1093\/protein\/13.1.15","volume":"13","author":"RD King","year":"2000","unstructured":"King RD, Ouali M, Strong AT, Aly A, Elmaghraby A, Kantardzic M, Page D: Is it better to combine predictions? Protein Eng 2000, 13(1):15\u201319. 10.1093\/protein\/13.1.15","journal-title":"Protein Eng"},{"key":"2563_CR20","first-page":"1","volume-title":"IIZUKA'94: 3rd International Conference on Fuzzy Logic, Neural Nets and Soft Computing: 1994; Iisuka, Japan","author":"LA Zadeh","year":"1994","unstructured":"Zadeh LA: Fuzzy Logic and Soft computing: Issues, Contention and Perspectives. IIZUKA'94: 3rd International Conference on Fuzzy Logic, Neural Nets and Soft Computing: 1994; Iisuka, Japan 1994, 1\u20132."},{"key":"2563_CR21","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1146\/annurev.iy.11.040193.001241","volume":"11","author":"HG Rammensee","year":"1993","unstructured":"Rammensee HG, Falk K, Rotzschke O: Peptides naturally presented by MHC class I molecules. Annu Rev Immunol 1993, 11: 213\u2013244. 10.1146\/annurev.iy.11.040193.001241","journal-title":"Annu Rev Immunol"},{"issue":"6468","key":"2563_CR22","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1038\/368215a0","volume":"368","author":"L Stern","year":"1994","unstructured":"Stern L, Brown J, Jardetzky T, Gorga J, Urban R, Strominger J, Wiley D: Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature 1994, 368(6468):215\u2013221. 10.1038\/368215a0","journal-title":"Nature"},{"issue":"1","key":"2563_CR23","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/0952-7915(95)80033-6","volume":"7","author":"HG Rammensee","year":"1995","unstructured":"Rammensee HG: Chemistry of peptides associated with MHC class I and class II molecules. Curr Opin Immunol 1995, 7(1):85\u201396. 10.1016\/0952-7915(95)80033-6","journal-title":"Curr Opin Immunol"},{"key":"2563_CR24","doi-asserted-by":"publisher","first-page":"3663","DOI":"10.1093\/nar\/22.17.3663","volume":"22","author":"V Brusic","year":"1994","unstructured":"Brusic V, Rudy G, Harrison LC: MHCPEP: a database of MHC-binding peptides. Nucleic Acids Res 1994, 22: 3663\u20133665. 10.1093\/nar\/22.17.3663","journal-title":"Nucleic Acids Res"},{"issue":"3","key":"2563_CR25","doi-asserted-by":"publisher","first-page":"e91","DOI":"10.1371\/journal.pbio.0030091","volume":"3","author":"B Peters","year":"2005","unstructured":"Peters B, Sidney J, Bourne P, Bui HH, Buus S, Doh G, Fleri W, Kronenberg M, Kubo R, Lund O, et al.: The immune epitope database and analysis resource: from vision to blueprint. PLoS Biol 2005, 3(3):e91. 10.1371\/journal.pbio.0030091","journal-title":"PLoS Biol"},{"issue":"3\u20134","key":"2563_CR26","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1007\/s002510050595","volume":"50","author":"HG Rammensee","year":"1999","unstructured":"Rammensee HG, Bachmann J, Emmerich NP, Bachor OA, Stevanovic S: SYFPEITHI: database for MHC ligands and peptide motifs. Immunogenetics 1999, 50(3\u20134):213\u2013219. 10.1007\/s002510050595","journal-title":"Immunogenetics"},{"key":"2563_CR27","volume-title":"International Conference on Biomedical and Pharmaceutical Engineering: 2006; Singapore","author":"GL Zhang","year":"2006","unstructured":"Zhang GL, Kwoh CK, August JT, Brusic V: Performance Evaluation of MULTIPRED1 on Prediction of MHC Class I Binders. International Conference on Biomedical and Pharmaceutical Engineering: 2006; Singapore 2006."},{"issue":"5","key":"2563_CR28","doi-asserted-by":"publisher","first-page":"1207","DOI":"10.1142\/S0219720005001466","volume":"3","author":"GL Zhang","year":"2005","unstructured":"Zhang GL, Khan AM, Srinivasan KN, August JT, Brusic V: Neural Models for predicting viral vaccine targets. J Bioinform Comput Biol 2005, 3(5):1207\u20131225. 10.1142\/S0219720005001466","journal-title":"J Bioinform Comput Biol"},{"key":"2563_CR29","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.jim.2006.12.011","volume":"320","author":"GL Zhang","year":"2007","unstructured":"Zhang GL, Bozic I, Kwoh CK, August JT, Brusic V: Prediction of supertype-specific HLA class I binding peptides using support vector machines. J Immunol Methods 2007, 320: 143\u2013154. 10.1016\/j.jim.2006.12.011","journal-title":"J Immunol Methods"},{"key":"2563_CR30","doi-asserted-by":"crossref","first-page":"3904","DOI":"10.4049\/jimmunol.152.8.3904","volume":"152","author":"WM Kast","year":"1994","unstructured":"Kast WM, Brandt RM, Sidney J, Drijfhout JW, Kubo RT, Grey HM, Melief CJ, Sette A: Role of HLA-A motifs in identification of potential CTL epitopes in human papillomavirus type 16 E6 and E7 proteins. J Immunol 1994, 152: 3904\u20133912.","journal-title":"J Immunol"},{"issue":"Suppl 1","key":"2563_CR31","doi-asserted-by":"publisher","first-page":"i297","DOI":"10.1093\/bioinformatics\/bth943","volume":"20","author":"KN Srinivasan","year":"2004","unstructured":"Srinivasan KN, Zhang GL, Khan AM, August JT, Brusic V: Prediction of Class I T-cell epitopes: evidence of presence of immunological hot spots inside antigens. Bioinformatics 2004, 20(Suppl 1):i297-i302. 10.1093\/bioinformatics\/bth943","journal-title":"Bioinformatics"},{"issue":"6","key":"2563_CR32","doi-asserted-by":"publisher","first-page":"e65","DOI":"10.1371\/journal.pcbi.0020065","volume":"2","author":"B Peters","year":"2006","unstructured":"Peters B, Bui HH, Frankild S, Nielson M, Lundegaard C, Kostem E, Basch D, Lamberth K, Harndahl M, Fleri W, et al.: A community resource benchmarking predictions of peptide binding to MHC-I molecules. PLoS Comput Biol 2006, 2(6):e65. 10.1371\/journal.pcbi.0020065","journal-title":"PLoS Comput Biol"},{"key":"2563_CR33","doi-asserted-by":"publisher","first-page":"W172","DOI":"10.1093\/nar\/gki452","volume":"33","author":"GL Zhang","year":"2005","unstructured":"Zhang GL, Khan AM, Srinivasan KN, August JT, Brusic V: MULTIPRED: a computational system for prediction of promiscuous HLA binding peptides. Nucleic Acids Res 2005, 33: W172-W179. 10.1093\/nar\/gki452","journal-title":"Nucleic Acids Res"},{"issue":"2","key":"2563_CR34","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/S0198-8859(02)00787-5","volume":"64","author":"JH Kessler","year":"2003","unstructured":"Kessler JH, Mommaas B, Mutis T, Huijbers I, Vissers D, Benckhuijsen WE, Schreuder GM, Offringa R, Goulmy E, Melief CJ, et al.: Competition-based cellular peptide binding assays for 13 prevalent HLA class I alleles using fluorescein-labeled synthetic peptides. Hum Immunol 2003, 64(2):245\u2013255. 10.1016\/S0198-8859(02)00787-5","journal-title":"Hum Immunol"},{"key":"2563_CR35","first-page":"6","volume":"5","author":"MM Bachinsky","year":"2005","unstructured":"Bachinsky MM, Guillen DE, Patel SR, Singleton J, Chen C, Soltis DA, Tussey LG: Mapping and binding analysis of peptides derived from the tumor-associated antigen survivin for eight HLA alleles. Cancer Immun 2005, 5: 6.","journal-title":"Cancer Immun"},{"issue":"1","key":"2563_CR36","doi-asserted-by":"publisher","first-page":"548","DOI":"10.4049\/jimmunol.169.1.548","volume":"169","author":"R Weissert","year":"2002","unstructured":"Weissert R, Kuhle J, de Graaf KL, Wienhold W, Herrmann MM, Muller C, Forsthuber TG, Wiesmuller KH, Melms A: High immunogenicity of intracellular myelin oligodendrocyte glycoprotein epitopes. J Immunol 2002, 169(1):548\u2013556.","journal-title":"J Immunol"},{"issue":"3","key":"2563_CR37","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/S0198-8859(99)00153-6","volume":"61","author":"F Borras-Cuesta","year":"2000","unstructured":"Borras-Cuesta F, Golvano J, Garcia-Granero M, Sarobe P, Riezu-Boj J, Huarte E, Lasarte J: Specific and general HLA-DR binding motifs: comparison of algorithms. Hum Immunol 2000, 61(3):266\u2013278. 10.1016\/S0198-8859(99)00153-6","journal-title":"Hum Immunol"},{"key":"2563_CR38","volume-title":"PhD thesis","author":"S Tongchusak","year":"2006","unstructured":"Tongchusak S: In silico prediction and immunological validation of candida albicans secretory aspartyl proteinase 2 peptides bound to multiple HLA-DRB1 supertypes. PhD thesis. Mahidol University; 2006."},{"issue":"1","key":"2563_CR39","doi-asserted-by":"crossref","first-page":"163","DOI":"10.4049\/jimmunol.152.1.163","volume":"152","author":"KC Parker","year":"1994","unstructured":"Parker KC, Bednarek MA, Coligan JE: Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains. J Immunol 1994, 152(1):163\u2013175.","journal-title":"J Immunol"},{"issue":"8","key":"2563_CR40","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1093\/bioinformatics\/btg108","volume":"19","author":"H Singh","year":"2003","unstructured":"Singh H, Raghava GP: ProPred1: prediction of promiscuous MHC Class-I binding sites. Bioinformatics 2003, 19(8):1009\u20131014. 10.1093\/bioinformatics\/btg108","journal-title":"Bioinformatics"},{"key":"2563_CR41","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1186\/1471-2105-6-132","volume":"6","author":"B Peters","year":"2005","unstructured":"Peters B, Sette A: Generating quantitative models describing the sequence specificity of biological processes with the stabilized matrix method. BMC Bioinformatics 2005, 6: 132. 10.1186\/1471-2105-6-132","journal-title":"BMC Bioinformatics"},{"issue":"3","key":"2563_CR42","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/S1093-3263(03)00160-8","volume":"22","author":"CK Hattotuwagama","year":"2004","unstructured":"Hattotuwagama CK, Guan P, Doytchinova IA, Zygouri C, Flower DR: Quantitative online prediction of peptide binding to the major histocompatibility complex. J Mol Graph Model 2004, 22(3):195\u2013207. 10.1016\/S1093-3263(03)00160-8","journal-title":"J Mol Graph Model"},{"key":"2563_CR43","doi-asserted-by":"publisher","first-page":"W194","DOI":"10.1093\/nar\/gkl284","volume":"34","author":"P Donnes","year":"2006","unstructured":"Donnes P, Kohlbacher O: SVMHC: a server for prediction of MHC-binding peptides. Nucleic Acids Res 2006, (34 Web Server):W194\u2013197. 10.1093\/nar\/gkl284","journal-title":"Nucleic Acids Res"},{"issue":"1","key":"2563_CR44","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1186\/1471-2105-3-25","volume":"3","author":"P Donnes","year":"2002","unstructured":"Donnes P, Elofsson A: Prediction of MHC class I binding peptides, using SVMHC. BMC Bioinformatics 2002, 3(1):25\u201338. 10.1186\/1471-2105-3-25","journal-title":"BMC Bioinformatics"},{"issue":"4","key":"2563_CR45","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.ymeth.2004.06.005","volume":"34","author":"N Petrovsky","year":"2004","unstructured":"Petrovsky N, Brusic V: Virtual models of the HLA class I antigen processing pathway. Methods 2004, 34(4):429\u2013435. 10.1016\/j.ymeth.2004.06.005","journal-title":"Methods"},{"issue":"8","key":"2563_CR46","doi-asserted-by":"publisher","first-page":"2295","DOI":"10.1002\/eji.200425811","volume":"35","author":"M Larsen","year":"2005","unstructured":"Larsen M, Lundegaard C, Lamberth K, Buus S, Brunak S, Lund O, Nielsen M: An integrative approach to CTL epitope prediction: a combined algorithm integrating MHC class I binding, TAP transport efficiency, and proteasomal cleavage predictions. Eur J Immunol 2005, 35(8):2295\u20132303. 10.1002\/eji.200425811","journal-title":"Eur J Immunol"},{"issue":"9","key":"2563_CR47","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1007\/s00018-005-4528-2","volume":"62","author":"S Tenzer","year":"2005","unstructured":"Tenzer S, Peters B, Bulik S, Schoor O, Lemmel C, Schatz MM, Kloetzel PM, Rammensee HG, Schild H, Holzhutter HG: Modeling the MHC class I pathway by combining predictions of proteasomal cleavage, TAP transport and MHC class I binding. Cell Mol Life Sci 2005, 62(9):1025\u20131037. 10.1007\/s00018-005-4528-2","journal-title":"Cell Mol Life Sci"},{"issue":"3\u20134","key":"2563_CR48","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/S0161-5890(02)00101-3","volume":"39","author":"M Gromme","year":"2002","unstructured":"Gromme M, Neefjes J: Antigen degradation or presentation by MHC class I molecules via classical and non-classical pathways. Mol Immunol 2002, 39(3\u20134):181\u2013202. 10.1016\/S0161-5890(02)00101-3","journal-title":"Mol Immunol"},{"issue":"2","key":"2563_CR49","doi-asserted-by":"crossref","first-page":"109","DOI":"10.3233\/ISB-00010","volume":"1","author":"V Brusic","year":"1999","unstructured":"Brusic V, van Endert P, Zeleznikow J, Daniel S, Hammer J, Petrovsky N: A neural network model approach to the study of human TAP transporter. In Silico Biol 1999, 1(2):109\u2013121.","journal-title":"In Silico Biol"},{"issue":"4","key":"2563_CR50","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1007\/s10989-005-9268-5","volume":"11","author":"S Tongchusak","year":"2005","unstructured":"Tongchusak S, Chaiyaroj SC, Veeramani A, Koh JLY, Brusic V: CandiVF \u2013 Candida albicans virulence factor database. Int J Pep Res Ther 2005, 11(4):271\u2013277. 10.1007\/s10989-005-9268-5","journal-title":"Int J Pep Res Ther"}],"container-title":["BMC Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2105-9-S1-S19.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2105-9-S1-S19\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2105-9-S1-S19.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T15:35:38Z","timestamp":1738078538000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcbioinformatics.biomedcentral.com\/articles\/10.1186\/1471-2105-9-S1-S19"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2]]},"references-count":50,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[2008,2]]}},"alternative-id":["2563"],"URL":"https:\/\/doi.org\/10.1186\/1471-2105-9-s1-s19","relation":{},"ISSN":["1471-2105"],"issn-type":[{"type":"electronic","value":"1471-2105"}],"subject":[],"published":{"date-parts":[[2008,2]]},"article-number":"S19"}}