{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T02:24:47Z","timestamp":1790303087572,"version":"4.1.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2006,9,29]],"date-time":"2006-09-29T00:00:00Z","timestamp":1159488000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Cell Biol"],"published-print":{"date-parts":[[2006,12]]},"DOI":"10.1186\/1471-2121-7-36","type":"journal-article","created":{"date-parts":[[2006,9,29]],"date-time":"2006-09-29T18:26:31Z","timestamp":1159554391000},"source":"Crossref","is-referenced-by-count":15,"title":["Hernia fibroblasts lack \u03b2-estradiol induced alterations of collagen gene expression"],"prefix":"10.1186","volume":"7","author":[{"given":"Petra Lynen","family":"Jansen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raphael","family":"Rosch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Rezvani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter R","family":"Mertens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karsten","family":"Junge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Jansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uwe","family":"Klinge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2006,9,29]]},"reference":[{"key":"209_CR1","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1046\/j.1365-2362.1997.2050752.x","volume":"27","author":"A Pans","year":"1997","unstructured":"Pans A, Pierard GE, Albert A, Desaive C: Adult groin hernias: new insight into their biomechanical characteristics. Eur J Clin Invest. 1997, 27: 863-868. 10.1046\/j.1365-2362.1997.2050752.x.","journal-title":"Eur J Clin Invest"},{"key":"209_CR2","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1067\/mob.2002.124845","volume":"187","author":"PA Moalli","year":"2002","unstructured":"Moalli PA, Klingensmith WL, Meyn LA, Zyczynski HM: Regulation of matrix metalloproteinase expression by estrogen in fibroblasts that are derived from the pelvic floor. Am J Obstet Gynecol. 2002, 187: 72-79. 10.1067\/mob.2002.124845.","journal-title":"Am J Obstet Gynecol"},{"key":"209_CR3","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1067\/msy.2002.121376","volume":"131","author":"Z Si","year":"2002","unstructured":"Si Z, Bhardwaj R, Rosch R, Mertens PR, Klosterhalfen B, Klinge U: Impaired balance of type I and type III procollagen mRNA in cultured fibroblasts of patients with incisional hernia. Surgery. 2002, 131: 324-331. 10.1067\/msy.2002.121376.","journal-title":"Surgery"},{"key":"209_CR4","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1097\/00000658-200102000-00020","volume":"233","author":"JM Bellon","year":"2001","unstructured":"Bellon JM, Bajo A, Ga-Honduvilla N, Gimeno MJ, Pascual G, Guerrero A: Fibroblasts from the transversalis fascia of young patients with direct inguinal hernias show constitutive MMP-2 overexpression. Ann Surg. 2001, 233: 287-291. 10.1097\/00000658-200102000-00020.","journal-title":"Ann Surg"},{"key":"209_CR5","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1007\/s00104-002-0425-5","volume":"73","author":"J Hoer","year":"2002","unstructured":"Hoer J, Lawong G, Klinge U, Schumpelick V: [Factors influencing the development of incisional hernia. A retrospective study of 2,983 laparotomy patients over a period of 10 years]. Chirurg. 2002, 73: 474-480. 10.1007\/s00104-002-0425-5.","journal-title":"Chirurg"},{"key":"209_CR6","doi-asserted-by":"publisher","first-page":"1597","DOI":"10.1016\/j.ajog.2003.09.043","volume":"189","author":"MY Wong","year":"2003","unstructured":"Wong MY, Harmanli OH, Agar M, Dandolu V, Grody MH: Collagen content of nonsupport tissue in pelvic organ prolapse and stress urinary incontinence. Am J Obstet Gynecol. 2003, 189: 1597-1599. 10.1016\/j.ajog.2003.09.043.","journal-title":"Am J Obstet Gynecol"},{"key":"209_CR7","doi-asserted-by":"publisher","first-page":"1309","DOI":"10.1172\/JCI16288","volume":"111","author":"GS Ashcroft","year":"2003","unstructured":"Ashcroft GS, Mills SJ, Lei K, Gibbons L, Jeong MJ, Taniguchi M: Estrogen modulates cutaneous wound healing by downregulating macrophage migration inhibitory factor. J Clin Invest. 2003, 111: 1309-10.1172\/JCI200316288.","journal-title":"J Clin Invest"},{"key":"209_CR8","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1016\/j.ajog.2003.08.040","volume":"190","author":"P Moalli","year":"2004","unstructured":"Moalli P, Talarico L, Sung V, Klingensmith W, Shand S, Meyn L: Impact of menopause on collagen subtypes in the arcus tendineous fasciae pelvis. Am J Obstet Gynecol. 2004, 190: 620-627. 10.1016\/j.ajog.2003.08.040.","journal-title":"Am J Obstet Gynecol"},{"key":"209_CR9","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1067\/msy.2002.119986","volume":"131","author":"LN Jorgensen","year":"2002","unstructured":"Jorgensen LN, Sorensen LT, Kallehave F, Vange J, Gottrup F: Premenopausal women deposit more collagen than men during healing of an experimental wound. Surgery. 2002, 131: 338-343. 10.1067\/msy.2002.119986.","journal-title":"Surgery"},{"key":"209_CR10","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1046\/j.1524-475X.2002.10605.x","volume":"10","author":"E Pirila","year":"2002","unstructured":"Pirila E, Parikka M, Ramamurthy NS, Maisi P, McClain S, Kucine A: Chemically modified tetracycline (CMT-8) and estrogen promote wound healing in ovariectomized rats: effects on matrix metalloproteinase-2, membrane type 1 matrix metalloproteinase, and laminin-5 gamma2-chain. Wound Repair Regen. 2002, 10: 38-51. 10.1046\/j.1524-475X.2002.10605.x.","journal-title":"Wound Repair Regen"},{"key":"209_CR11","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1159\/000008740","volume":"32","author":"U Klinge","year":"2000","unstructured":"Klinge U, Si ZY, Zheng H, Schumpelick V, Bhardwaj RS, Klosterhalfen B: Abnormal collagen I to III distribution in the skin of patients with incisional hernia. Eur Surg Res. 2000, 32: 43-48. 10.1159\/000008740.","journal-title":"Eur Surg Res"},{"key":"209_CR12","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1159\/000008728","volume":"31","author":"U Klinge","year":"1999","unstructured":"Klinge U, Zheng H, Si Z, Schumpelick V, Bhardwaj RS, Muys L: Expression of the extracellular matrix proteins collagen I, collagen III and fibronectin and matrix metalloproteinase-1 and -13 in the skin of patients with inguinal hernia. Eur Surg Res. 1999, 31: 480-490. 10.1159\/000008728.","journal-title":"Eur Surg Res"},{"key":"209_CR13","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1007\/BF01194422","volume":"3","author":"U Klinge","year":"1999","unstructured":"Klinge U, Zheng H, Si ZY, Bhardwaj R, Klosterhalfen B, Schumpelick V: Altered collagen synthesis in fascia transversalis of patients with inguinal hernia. Hernia. 1999, 3: 181-187. 10.1007\/BF01194422.","journal-title":"Hernia"},{"key":"209_CR14","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1080\/089419301750072202","volume":"14","author":"U Klinge","year":"2001","unstructured":"Klinge U, Si ZY, Zheng H, Schumpelick V, Bhardwaj RS, Klosterhalfen B: Collagen I\/III and matrix metalloproteinases (MMP) 1 and 13 in the fascia of patients with incisional hernias. J Invest Surg. 2001, 14: 47-54. 10.1080\/089419301750072202.","journal-title":"J Invest Surg"},{"key":"209_CR15","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1016\/j.matbio.2004.07.004","volume":"23","author":"CY Lee","year":"2004","unstructured":"Lee CY, Liu X, Smith CL, Zhang X, Hsu HC, Wang DY: The combined regulation of estrogen and cyclic tension on fibroblast biosynthesis derived from anterior cruciate ligament. Matrix Biol. 2004, 23: 323-329. 10.1016\/j.matbio.2004.07.004.","journal-title":"Matrix Biol"},{"key":"209_CR16","first-page":"H617","volume":"232","author":"GM Fischer","year":"1977","unstructured":"Fischer GM, Swain ML: Effect of sex hormones on blood pressure and vascular connective tissue in castrated and noncastrated male rats. Am J Physiol. 1977, 232: H617-H621.","journal-title":"Am J Physiol"},{"key":"209_CR17","doi-asserted-by":"publisher","first-page":"473","DOI":"10.3109\/17453677608988723","volume":"47","author":"H Hama","year":"1976","unstructured":"Hama H, Yamamuro T, Takeda T: Experimental studies on connective tissue of the capsular ligament. Influences of aging and sex hormones. Acta Orthop Scand. 1976, 47: 473-479.","journal-title":"Acta Orthop Scand"},{"key":"209_CR18","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.1016\/0026-0495(90)90089-U","volume":"39","author":"C Hassager","year":"1990","unstructured":"Hassager C, Jensen LT, Podenphant J, Riis BJ, Christiansen C: Collagen synthesis in postmenopausal women during therapy with anabolic steroid or female sex hormones. Metabolism. 1990, 39: 1167-1169. 10.1016\/0026-0495(90)90089-U.","journal-title":"Metabolism"},{"key":"209_CR19","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/0026-0495(91)90176-W","volume":"40","author":"C Hassager","year":"1991","unstructured":"Hassager C, Jensen LT, Johansen JS, Riis BJ, Melkko J, Podenphant J: The carboxy-terminal propeptide of type I procollagen in serum as a marker of bone formation: the effect of nandrolone decanoate and female sex hormones. Metabolism. 1991, 40: 205-208. 10.1016\/0026-0495(91)90176-W.","journal-title":"Metabolism"},{"key":"209_CR20","first-page":"268","volume-title":"Clin Orthop","author":"WD Yu","year":"2001","unstructured":"Yu WD, Panossian V, Hatch JD, Liu SH, Finerman GA: Combined effects of estrogen and progesterone on the anterior cruciate ligament. Clin Orthop. 2001, 268-281."},{"key":"209_CR21","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1067\/msy.2003.24","volume":"133","author":"MD Basson","year":"2003","unstructured":"Basson MD: Invited research review: Cell-matrix interactions in the gut epithelium. Surgery. 2003, 133: 263-267. 10.1067\/msy.2003.24.","journal-title":"Surgery"},{"issue":"Suppl","key":"209_CR22","doi-asserted-by":"publisher","first-page":"S47","DOI":"10.1007\/PL00007453","volume":"290","author":"UK Saarialho-Kere","year":"1998","unstructured":"Saarialho-Kere UK: Patterns of matrix metalloproteinase and TIMP expression in chronic ulcers. Arch Dermatol Res. 1998, 290 (Suppl): S47-S54. 10.1007\/PL00007453.","journal-title":"Arch Dermatol Res"},{"key":"209_CR23","doi-asserted-by":"publisher","first-page":"3606","DOI":"10.1074\/jbc.M107571200","volume":"277","author":"E Olaso","year":"2002","unstructured":"Olaso E, Labrador JP, Wang L, Ikeda K, Eng FJ, Klein R: Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2. J Biol Chem. 2002, 277: 3606-3613. 10.1074\/jbc.M107571200.","journal-title":"J Biol Chem"},{"key":"209_CR24","first-page":"1","volume-title":"Hernia","author":"R Rosch","year":"2006","unstructured":"Rosch R, Lynen-Jansen P, Junge K, Knops M, Klosterhalfen B, Klinge U: Biomaterial-dependent MMP-2 expression in fibroblasts from patients with recurrent incisional hernias. Hernia. 2006, 1-6."},{"key":"209_CR25","volume-title":"Calcified Tissue International","author":"KG Zecchin","year":"2005","unstructured":"Zecchin KG, Pereira MC, Coletta RD, Graner E, Jorge J: Ovariectomy Reduces the Gelatinolytic Activity and Expression of Matrix Metalloproteinases and Collagen in Rat Molar Extraction Wounds. Calcified Tissue International. 2005"},{"key":"209_CR26","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1111\/j.1471-0528.2002.01052.x","volume":"109","author":"S Jackson","year":"2002","unstructured":"Jackson S, James M, Abrams P: The effect of oestradiol on vaginal collagen metabolism in postmenopausal women with genuine stress incontinence. BJOG. 2002, 109: 339-344.","journal-title":"BJOG"},{"key":"209_CR27","doi-asserted-by":"publisher","first-page":"2701","DOI":"10.1074\/jbc.M205692200","volume":"278","author":"M Razandi","year":"2003","unstructured":"Razandi M, Pedram A, Park ST, Levin ER: Proximal Events in Signaling by Plasma Membrane Estrogen Receptors. J Biol Chem. 2003, 278: 2701-2712. 10.1074\/jbc.M205692200.","journal-title":"J Biol Chem"},{"key":"209_CR28","doi-asserted-by":"crossref","first-page":"F309","DOI":"10.1152\/ajprenal.2000.279.2.F309","volume":"279","author":"J Neugarten","year":"2000","unstructured":"Neugarten J, Acharya A, Lei J, Silbiger S: Selective estrogen receptor modulators suppress mesangial cell collagen synthesis. Am J Physiol Renal Physiol. 2000, 279: F309-F318.","journal-title":"Am J Physiol Renal Physiol"},{"key":"209_CR29","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1007\/s00268-001-0239-5","volume":"26","author":"H Zheng","year":"2002","unstructured":"Zheng H, Si Z, Kasperk R, Bhardwaj RS, Schumpelick V, Klinge U: Recurrent inguinal hernia: disease of the collagen matrix?. World J Surg. 2002, 26: 401-408. 10.1007\/s00268-001-0239-5.","journal-title":"World J Surg"},{"key":"209_CR30","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1177\/036354659702500521","volume":"25","author":"SH Liu","year":"1997","unstructured":"Liu SH, Al Shaikh RA, Panossian V, Finerman GA, Lane JM: Estrogen affects the cellular metabolism of the anterior cruciate ligament. A potential explanation for female athletic injury. Am J Sports Med. 1997, 25: 704-709.","journal-title":"Am J Sports Med"}],"container-title":["BMC Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2121-7-36.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2121-7-36\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2121-7-36.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,22]],"date-time":"2019-01-22T21:08:50Z","timestamp":1548191330000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcmolcellbiol.biomedcentral.com\/articles\/10.1186\/1471-2121-7-36"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,9,29]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["209"],"URL":"https:\/\/doi.org\/10.1186\/1471-2121-7-36","relation":{},"ISSN":["1471-2121"],"issn-type":[{"value":"1471-2121","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,9,29]]},"article-number":"36"}}