{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T06:02:03Z","timestamp":1791093723269,"version":"4.1.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Genet"],"published-print":{"date-parts":[[2006,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Panda (<jats:italic>s<\/jats:italic>) is an autosomal recessive mutation, which displays overall white plumage color with spots of wild-type plumage in the Japanese quail (<jats:italic>Coturnix japonica<\/jats:italic>). In a previous study, the <jats:italic>s<\/jats:italic> locus was included in the same linkage group as serum albumin (<jats:italic>Alb<\/jats:italic>) and vitamin-D binding protein (<jats:italic>GC<\/jats:italic>) which are mapped on chicken (<jats:italic>Gallus gallus<\/jats:italic>) chromosome 4 (GGA4). In this study, we mapped the <jats:italic>s<\/jats:italic> locus on the microsatellite linkage map of the Japanese quail by linkage analysis.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Segregation data on the <jats:italic>s<\/jats:italic> locus were obtained from three-generation families (<jats:italic>n<\/jats:italic> = 106). Two microsatellite markers derived from the Japanese quail chromosome 4 (CJA04) and three microsatellite markers derived from GGA4 were genotyped in the three-generation families. We mapped the <jats:italic>s<\/jats:italic> locus between <jats:italic>GUJ0026<\/jats:italic> and <jats:italic>ABR0544<\/jats:italic> on CJA04. By comparative mapping with chicken, this locus was mapped between 10.0 Mb and 14.5 Mb region on GGA4. In this region, the endothelin receptor B subtype 2 gene (<jats:italic>EDNRB2<\/jats:italic>), an avian-specific paralog of the mammalian endothelin receptor B gene (<jats:italic>EDNRB<\/jats:italic>), is located. Because <jats:italic>EDNRB<\/jats:italic> is responsible for aganglionic megacolon and spot coat color in mouse, rat and equine, <jats:italic>EDNRB2<\/jats:italic> is suggested to be a candidate gene for the <jats:italic>s<\/jats:italic> locus.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>The <jats:italic>s<\/jats:italic> locus and the five microsatellite markers were mapped on CJA04 of the Japanese quail. <jats:italic>EDNRB2<\/jats:italic> was suggested to be a candidate gene for the <jats:italic>s<\/jats:italic> locus.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1471-2156-7-2","type":"journal-article","created":{"date-parts":[[2006,1,23]],"date-time":"2006-01-23T12:36:56Z","timestamp":1138019816000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Mapping of panda plumage color locus on the microsatellite linkage map of the Japanese quail"],"prefix":"10.1186","volume":"7","author":[{"given":"Mitsuru","family":"Miwa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miho","family":"Inoue-Murayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boniface Baboreka","family":"Kayang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Mizutani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin'ichi","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2006,1,12]]},"reference":[{"key":"425_CR1","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1538\/expanim1957.23.2_59","volume":"23","author":"M Mizutani","year":"1974","unstructured":"Mizutani M, Chino K, Umezawa H, Kuramasu S: Genetic analysis of a new plumage \u2013 panda in Japanese quail. 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