{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T23:23:49Z","timestamp":1791069829945,"version":"4.1.0"},"reference-count":58,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2010,11,20]],"date-time":"2010-11-20T00:00:00Z","timestamp":1290211200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2010,11,20]],"date-time":"2010-11-20T00:00:00Z","timestamp":1290211200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Genomics"],"published-print":{"date-parts":[[2010,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Widespread use of chromium (Cr) contaminated fields due to careless and inappropriate management practices of effluent discharge, mostly from industries related to metallurgy, electroplating, production of paints and pigments, tanning, and wood preservation elevates its concentration in surface soil and eventually into rice plants and grains. In spite of many previous studies having been conducted on the effects of chromium stress, the precise molecular mechanisms related to both the effects of chromium phytotoxicity, the defense reactions of plants against chromium exposure as well as translocation and accumulation in rice remain poorly understood.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Detailed analysis of genome-wide transcriptome profiling in rice root is reported here, following Cr-plant interaction. Such studies are important for the identification of genes responsible for tolerance, accumulation and defense response in plants with respect to Cr stress. Rice root metabolome analysis was also carried out to relate differential transcriptome data to biological processes affected by Cr (VI) stress in rice. To check whether the Cr-specific motifs were indeed significantly over represented in the promoter regions of Cr-responsive genes, occurrence of these motifs in whole genome sequence was carried out. In the background of whole genome, the lift value for these 14 and 13 motifs was significantly high in the test dataset. Though no functional role has been assigned to any of the motifs, but all of these are present as promoter motifs in the Database of orthologus promoters.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>These findings clearly suggest that a complex network of regulatory pathways modulates Cr-response of rice. The integrated matrix of both transcriptome and metabolome data after suitable normalization and initial calculations provided us a visual picture of the correlations between components. Predominance of different motifs in the subsets of genes suggests the involvement of motif-specific transcription modulating proteins in Cr stress response of rice.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1471-2164-11-648","type":"journal-article","created":{"date-parts":[[2010,11,20]],"date-time":"2010-11-20T07:14:12Z","timestamp":1290237252000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":175,"title":["Transcriptomic and metabolomic shifts in rice roots in response to Cr (VI) stress"],"prefix":"10.1186","volume":"11","author":[{"given":"Sonali","family":"Dubey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prashant","family":"Misra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Dwivedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandipan","family":"Chatterjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumit K","family":"Bag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shrikant","family":"Mantri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehar H","family":"Asif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arti","family":"Rai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smita","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manju","family":"Shri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preeti","family":"Tripathi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudra D","family":"Tripathi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prabodh K","family":"Trivedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debasis","family":"Chakrabarty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rakesh","family":"Tuli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,11,20]]},"reference":[{"key":"10099_CR1","volume-title":"Chromium in natural and human environments","author":"JO Nriagu","year":"1988","unstructured":"Nriagu JO, Neiborer E: Chromium in natural and human environments. 1988, New York: Wiley"},{"key":"10099_CR2","volume-title":"The biological and environmental chemistry of chromium","author":"SA Katz","year":"1994","unstructured":"Katz SA, Salem H: The biological and environmental chemistry of chromium. 1994, New York: VHC Publishers"},{"key":"10099_CR3","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1039\/b904571f","volume":"1","author":"AK Shanker","year":"2009","unstructured":"Shanker AK, Djanaguiraman M, Venkateswarlu B: Chromium interactions in plants: current status and future strategies. Metallomics. 2009, 1: 375-383. 10.1039\/b904571f.","journal-title":"Metallomics"},{"key":"10099_CR4","first-page":"167","volume":"12","author":"HT Lin","year":"2004","unstructured":"Lin HT, Wong SS, Li GC: Heavy metal content of rice and Shellfish in Taiwan. J Food and Drug Analysis. 2004, 12: 167-174.","journal-title":"J Food and Drug Analysis"},{"key":"10099_CR5","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.envint.2005.02.003","volume":"31","author":"AK Shanker","year":"2005","unstructured":"Shanker AK, Cervantes C, Tavera H, Avudainayagam S: Chromium toxicity in plants. Enviorn Int. 2005, 31: 739-753. 10.1016\/j.envint.2005.02.003.","journal-title":"Enviorn Int"},{"key":"10099_CR6","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1016\/j.chemosphere.2005.02.024","volume":"60","author":"P Bhattacharyya","year":"2005","unstructured":"Bhattacharyya P, Chakraborty A, Chakrabarti K, Tripathy S, Powell MS: Chromium uptake by rice and accumulation in soil amended with municipal solid waste compost. Chemosphere. 2005, 60: 1481-1486. 10.1016\/j.chemosphere.2005.02.024.","journal-title":"Chemosphere"},{"key":"10099_CR7","first-page":"60","volume":"1","author":"MA Zazouli","year":"2006","unstructured":"Zazouli MA, Shokrzadeh M, Mohseni A, Bazrafshan E: Study of chromium concentration in tarrom rice cultivated in the Qaemshahr region and its daily intake. World Applied Sciences Journal. 2006, 1: 60-65.","journal-title":"World Applied Sciences Journal"},{"key":"10099_CR8","first-page":"61","volume-title":"Chromium, environment health criteria","author":"WHO","year":"1988","unstructured":"WHO: Chromium, environment health criteria. 1988, World Health Organization, Geneva, Switzerland, 61-"},{"key":"10099_CR9","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1023\/A:1022871131698","volume":"46","author":"SK Panda","year":"2003","unstructured":"Panda SK, Chaudhury I, Khan MH: Heavy metals induce lipid peroxidation and affects antioxidants in wheat leaves. Biol Plant. 2003, 46: 289-296. 10.1023\/A:1022871131698.","journal-title":"Biol Plant"},{"key":"10099_CR10","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1590\/S1677-04202005000100008","volume":"17","author":"SK Panda","year":"2005","unstructured":"Panda SK, Choudhury S: Chromium stress in plants. Braz Plant Physiol. 2005, 17: 95-102.","journal-title":"Braz Plant Physiol"},{"key":"10099_CR11","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/j.jplph.2007.01.012","volume":"164","author":"SK Panda","year":"2007","unstructured":"Panda SK: Chromium-mediated oxidative stress and ultrastructural changes in root cells of developing rice seedlings. Journal of Plant Physiology. 2007, 164: 1419-1428. 10.1016\/j.jplph.2007.01.012.","journal-title":"Journal of Plant Physiology"},{"key":"10099_CR12","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1111\/j.1469-8137.1982.tb03395.x","volume":"92","author":"SP Mc Grath","year":"1982","unstructured":"Mc Grath SP: The uptake and translocation of tin and hexavalent chromium and effects on growth of oat in flowering nutrient solution and in soil. New Phytol. 1982, 92: 381-390. 10.1111\/j.1469-8137.1982.tb03395.x.","journal-title":"New Phytol"},{"key":"10099_CR13","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.gene.2007.07.021","volume":"402","author":"S Quaggiotti","year":"2007","unstructured":"Quaggiotti S, Barcaccia G, Schiavon M, Nicol\u00e9 S, Galla G, Rossignolo V, Soattin M, Malagoli M: Phytoremediation of chromium using Salix species: Cloning ESTs and candidate genes involved in the Cr response. Gene. 2007, 402: 68-80. 10.1016\/j.gene.2007.07.021.","journal-title":"Gene"},{"key":"10099_CR14","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1104\/pp.104.900188","volume":"140","author":"AK Grennan","year":"2006","unstructured":"Grennan AK: Abiotic Stress in Rice. An \"Omic\" Approach. Plant Physiology. 2006, 140: 1139-1141. 10.1104\/pp.104.900188.","journal-title":"Plant Physiology"},{"key":"10099_CR15","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.pbi.2006.05.014","volume":"9","author":"M Fujita","year":"2006","unstructured":"Fujita M, Fujita Y, Noutoshi Y, Takahashi F, Narusaka Y, Yamaguchi K, Shinozaki : Crosstalk between abiotic and biotic stress responses: a current view from the points of convergence in the stress signaling networks. Current Opinion in Plant Biology. 2006, 9: 436-442. 10.1016\/j.pbi.2006.05.014.","journal-title":"Current Opinion in Plant Biology"},{"key":"10099_CR16","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/j.chemosphere.2008.09.082","volume":"74","author":"D Chakrabarty","year":"2009","unstructured":"Chakrabarty D, Trivedi PK, Misra P, Tiwari M, Shri M, Shukla D, Kumar S, Rai A, Pandey A, Nigam D, Tripathi RD, Tuli R: Comparative transcriptome analysis of arsenate and arsenite stresses in rice seedlings. Chemosphere. 2009, 74: 688-702. 10.1016\/j.chemosphere.2008.09.082.","journal-title":"Chemosphere"},{"key":"10099_CR17","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/S0981-9428(01)01289-X","volume":"39","author":"C Bailly","year":"2001","unstructured":"Bailly C, Corbineau F, Doorn WG: Free radical scavenging and senescence in Iris tepals. Plant Physiology and Biochemistry. 2001, 39: 649-656. 10.1016\/S0981-9428(01)01289-X.","journal-title":"Plant Physiology and Biochemistry"},{"key":"10099_CR18","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.aquatox.2007.11.001","volume":"86","author":"S Mishra","year":"2008","unstructured":"Mishra S, Srivastava S, Tripathi RD, Trivedi PK: Thiol metabolism and antioxidant systems complement each other during arsenate detoxification in Ceratophyllum demersum L. Aquatic Toxicology. 2008, 86: 205-215. 10.1016\/j.aquatox.2007.11.001.","journal-title":"Aquatic Toxicology"},{"key":"10099_CR19","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1016\/j.ecoenv.2008.09.022","volume":"72","author":"Shri Manju","year":"2009","unstructured":"Manju Shri, Kumar S, Chakrabarty D, Trivedi PK, Mallick S, Misra P, Shukla D, Mishra S, Srivastava S, Tripathi RD, Tuli R: Effect of arsenic on growth, oxidative stress and antioxidant system in rice seedlings. Ecotoxicology and Environmental Safety. 2009, 72: 1102-1110. 10.1016\/j.ecoenv.2008.09.022.","journal-title":"Ecotoxicology and Environmental Safety"},{"key":"10099_CR20","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1111\/j.1399-3054.1986.tb05764.x","volume":"67","author":"A Paulin","year":"1986","unstructured":"Paulin A, Droillard M, Bureau JM: Effect of a free radical scavenger, 3,4,5-trichlorophenol, on ethylene production and on changes in lipids and membrane integrity during senescence of petals of cut carnations (Dianthus carvophyllus). Physiologia Plantarum. 1986, 67: 465-71. 10.1111\/j.1399-3054.1986.tb05764.x.","journal-title":"Physiologia Plantarum"},{"key":"10099_CR21","volume-title":"Bioresourse Technology","author":"R Singh","year":"2010","unstructured":"Singh R, Tripathi RD, Dwivedi S, Kumar A, Trivedi PK, Chakrabarty D: Lead bioaccumulation potential of an aquatic macrophyte Najas indica are related 3 to antioxidant system. Bioresourse Technology. 2010"},{"key":"10099_CR22","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1023\/A:1002873531707","volume":"43","author":"MMF Mansour","year":"2000","unstructured":"Mansour MMF: Nitrogen containing compounds and adaptation of plants to salinity stress. Biol Plant. 2000, 43: 491-500. 10.1023\/A:1002873531707.","journal-title":"Biol Plant"},{"key":"10099_CR23","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/S0981-9428(98)80028-4","volume":"36","author":"MMF Mansour","year":"1998","unstructured":"Mansour MMF: Protection of plasma membrane of onion epidermal cells by glycine betaine and proline against NaCl stress. Plant Physiol Biochem. 1998, 36: 767-772. 10.1016\/S0981-9428(98)80028-4.","journal-title":"Plant Physiol Biochem"},{"key":"10099_CR24","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/j.jplph.2007.01.012","volume":"164","author":"SK Panda","year":"2007","unstructured":"Panda SK: Chromium-mediated oxidative stress and ultrastructural changes in root cells of developing rice seedlings. Journal of Plant Physiology. 2007, 164: 1419-1428. 10.1016\/j.jplph.2007.01.012.","journal-title":"Journal of Plant Physiology"},{"key":"10099_CR25","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1021\/tx00024a003","volume":"4","author":"AM Standeven","year":"1991","unstructured":"Standeven AM, Wetterhahn KE: Is there a role for reactive oxygen species in the mechanism of chromium(VI) carcinogenesis?. Chemical research in toxicology. 1991, 4: 616-625. 10.1021\/tx00024a003.","journal-title":"Chemical research in toxicology"},{"key":"10099_CR26","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s00425-006-0473-z","volume":"226","author":"L Li","year":"2007","unstructured":"Li L, Cheng H, Gai J, Yu D: Genome-wide identiWcation and characterization of putative cytochrome P450 genes in the model legume Medicago truncatula. Planta. 2007, 226: 109-123. 10.1007\/s00425-006-0473-z.","journal-title":"Planta"},{"key":"10099_CR27","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.envexpbot.2009.03.016","volume":"67","author":"T Liu","year":"2009","unstructured":"Liu T, Liu S, Guan H, Ma L, Chen Z, Gu H, Qu LJ: Transcriptional profiling of Arabidopsis seedlings in response to heavy metal lead (Pb). Environmental and Experimental Botany. 2009, 67: 377-386. 10.1016\/j.envexpbot.2009.03.016.","journal-title":"Environmental and Experimental Botany"},{"key":"10099_CR28","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1159\/000121332","volume":"15","author":"H Kawahigashi","year":"2008","unstructured":"Kawahigashi H, Hirose S, Ohkawa H, Ohkawa Y: Transgenic Rice Plants Expressing Human P450 Genes Involved in Xenobiotic Metabolism for Phytoremediation. J Mol Micro & Biotech. 2008, 15: 212-219.","journal-title":"J Mol Micro & Biotech"},{"key":"10099_CR29","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s10722-009-9451-1","volume":"57","author":"N Iqbal","year":"2010","unstructured":"Iqbal N, Farooq S, Arshad S, Hameed A: Differential accumulation of high and low molecular weight heat shock proteins in Basmati rice (Oryza sativa L.) cultivars. Genetic Resources and Crop Evolution. 2010, 57: 65-70. 10.1007\/s10722-009-9451-1.","journal-title":"Genetic Resources and Crop Evolution"},{"key":"10099_CR30","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1016\/j.jplph.2009.01.015","volume":"166","author":"P Goupila","year":"2009","unstructured":"Goupila P, Souguira D, Ferjani E, Faure O, Hitmi A, Ledoigt G: Expression of stress-related genes in tomato plants exposed to arsenic and chromium in nutrient solution. J Plant Physiol. 2009, 166: 1446--1452. 10.1016\/j.jplph.2009.01.015.","journal-title":"J Plant Physiol"},{"key":"10099_CR31","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1111\/j.1399-3054.1996.tb00546.x","volume":"97","author":"TJ Close","year":"1996","unstructured":"Close TJ: Dehydrins: emergence of a biochemical role of a family of plant dehydration proteins. Physiol Plant. 1996, 97: 795-803. 10.1111\/j.1399-3054.1996.tb00546.x.","journal-title":"Physiol Plant"},{"key":"10099_CR32","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1007\/s00300-005-0718-5","volume":"28","author":"NO Concha","year":"2005","unstructured":"Concha NO, Bravo LA, Lara SR, Corcuera LJ: Differential accumulation of dehydrin-like proteins by abiotic stresses in Deschampsia antarctica Desv. Polar Biology. 2005, 28: 506-512. 10.1007\/s00300-005-0718-5.","journal-title":"Polar Biology"},{"key":"10099_CR33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jexbot\/53.366.1","volume":"53","author":"JL Hall","year":"2002","unstructured":"Hall JL: Cellular mechanisms for heavy metal detoxification and tolerance. Journal of Experimental Botany. 2002, 53: 1-11. 10.1093\/jexbot\/53.366.1.","journal-title":"Journal of Experimental Botany"},{"key":"10099_CR34","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1093\/carcin\/12.9.1733","volume":"12","author":"AM Standeven","year":"1991","unstructured":"Standeven AM, Wetterhahn KE: Ascorbate is the principal reductant of chromium(VI) in rat liver and kidney ultrafiltrates. Carcinogenesis. 1991, 12: 1733-1737. 10.1093\/carcin\/12.9.1733.","journal-title":"Carcinogenesis"},{"key":"10099_CR35","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1104\/pp.105.076240","volume":"141","author":"FF Nocito","year":"2006","unstructured":"Nocito FF, Lancilli C, Crema B, Fourcroy P, Davidian J, Sacchi GA: Heavy metal stress and sulfate uptake in maize roots. Plant Physiology. 2006, 141: 1138-1148. 10.1104\/pp.105.076240.","journal-title":"Plant Physiology"},{"key":"10099_CR36","doi-asserted-by":"crossref","first-page":"726","DOI":"10.2134\/jeq2005.0119","volume":"35","author":"SD Lindblom","year":"2006","unstructured":"Lindblom SD, Abdel-Ghany S, Hanson BR, Hwang S, Terry N, Pilon-Smits EAH: Constitutive expression of a high-affinity sulfate transporter in Indian mustard affects metal tolerance and accumulation. Journal of Environmental Quality. 2006, 35: 726-733. 10.2134\/jeq2005.0119.","journal-title":"Journal of Environmental Quality"},{"key":"10099_CR37","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1105\/tpc.010376","volume":"14","author":"C Nawrath","year":"2002","unstructured":"Nawrath C, et al: EDS5, an essential component of salicylic acid-dependent signaling for disease resistance in Arabidopsis, is a member of the MATE transporter family. Plant Cell. 2002, 14: 275-286. 10.1105\/tpc.010376.","journal-title":"Plant Cell"},{"key":"10099_CR38","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.1574-6976.2001.tb00581.x","volume":"25","author":"C Cervantes","year":"2001","unstructured":"Cervantes C, Garcia JC, Devars S, Corona FG, Tavera HL, Torres-guzman JC: Interactions of chromium with micro-organisms and plants. FEMS Microbiol Rev. 2001, 25: 335-47. 10.1111\/j.1574-6976.2001.tb00581.x.","journal-title":"FEMS Microbiol Rev"},{"key":"10099_CR39","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/S1360-1385(01)02103-3","volume":"6","author":"S Zhang","year":"2001","unstructured":"Zhang S, Klessig DF: MAPK cascades in plant defense signaling. Trends in Plant Science. 2001, 6: 520-527. 10.1016\/S1360-1385(01)02103-3.","journal-title":"Trends in Plant Science"},{"key":"10099_CR40","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1007\/s10142-009-0118-y","volume":"9","author":"MH Asif","year":"2009","unstructured":"Asif MH, Trivedi PK, Misra P, Nath P: Prolyl-4-hydroxylase (AtP4H1) mediates and mimics low oxygen response in Arabidopsis thaliana. Functional and Integrative Genomics. 2009, 9: 525-535. 10.1007\/s10142-009-0118-y.","journal-title":"Functional and Integrative Genomics"},{"key":"10099_CR41","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1016\/S0006-3495(96)79410-9","volume":"71","author":"A Wang","year":"1996","unstructured":"Wang A, Bolen DW: Effect of proline on lactate dehydrogenase activity: testing the generality and scope of the compatibility paradigm. Biophys J. 1996, 71: 2117-2122. 10.1016\/S0006-3495(96)79410-9.","journal-title":"Biophys J"},{"key":"10099_CR42","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/s11738-008-0251-6","volume":"31","author":"KV Chaitanya","year":"2009","unstructured":"Chaitanya KV, Rasineni GK, Reddy AR: Biochemical responses to drought stress in mulberry (Morus alba L.): evaluation of proline, glycine betaine and abscisic acid accumulation in five cultivars. Acta Physiol Plant. 2009, 31: 437-443. 10.1007\/s11738-008-0251-6.","journal-title":"Acta Physiol Plant"},{"key":"10099_CR43","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.plantsci.2008.12.006","volume":"176","author":"Y Sato","year":"2009","unstructured":"Sato Y, Ashihar H: Long-term effect of NaCl on the activity of uridine and uracil salvage for nucleotide synthesis in cultured mangrove (Bruguiera sexangula) cells. Plant Science. 2009, 176: 383-389. 10.1016\/j.plantsci.2008.12.006.","journal-title":"Plant Science"},{"key":"10099_CR44","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1099\/00221287-147-8-2255","volume":"147","author":"ME Guerzoni","year":"2001","unstructured":"Guerzoni ME, Lanciotti R, Cocconcelli PS: Alteration in cellular fatty acid composition as a response to salt, acid, oxidative and thermal stresses in Lactobacillus helveticus. Microbiology. 2001, 147: 2255-2264.","journal-title":"Microbiology"},{"key":"10099_CR45","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.phytochem.2009.01.014","volume":"70","author":"L L\u00f3pez-P\u00e9rez","year":"2009","unstructured":"L\u00f3pez-P\u00e9rez L, Mart\u00ednez-Ballesta MC, Maurel C, Carvajal M: Changes in plasma membrane lipids, aquaporins and proton pump of broccoli roots, as an adaptation mechanism to salinity. Phytochemistry. 2009, 70: 492-500. 10.1016\/j.phytochem.2009.01.014.","journal-title":"Phytochemistry"},{"key":"10099_CR46","first-page":"78","volume":"2","author":"C Badea","year":"2009","unstructured":"Badea C, Basu SK: The effect of low temperature on metabolism of membrane lipids in plants and associated gene expression. Plant Omics Journal. 2009, 2: 78-84.","journal-title":"Plant Omics Journal"},{"key":"10099_CR47","first-page":"8","volume":"27","author":"K Doi","year":"2008","unstructured":"Doi K, Hosaka A, Nagata T, Satoh K, Suzuki K, Mauleon R, Mendoza MJ, Bruskiewich R, Kikuchi S: Development of a novel data mining tool to find cis-elements in rice gene promoter regions. BMC Plant Biol. 2008, 27: 8-20.","journal-title":"BMC Plant Biol"},{"key":"10099_CR48","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1104\/pp.104.057984","volume":"138","author":"K Tatematsu","year":"2005","unstructured":"Tatematsu K, Ward S, Leyser O, Kamiya Y, Nambara E: Identification of cis-Elements That Regulate Gene Expression during Initiation of Axillary Bud Outgrowth in Arabidopsis. Plant Physiology. 2005, 138: 757-766. 10.1104\/pp.104.057984.","journal-title":"Plant Physiology"},{"key":"10099_CR49","doi-asserted-by":"crossref","first-page":"10120","DOI":"10.1074\/jbc.273.17.10120","volume":"273","author":"CA Lu","year":"1998","unstructured":"Lu CA, Lim EK, Yu SM: Sugar response sequence in the promoter of a rice -amylase gene serves as a transcriptional enhancer. J Biol Chem. 1998, 273: 10120-10131. 10.1074\/jbc.273.17.10120.","journal-title":"J Biol Chem"},{"key":"10099_CR50","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0003-9861(68)90654-1","volume":"125","author":"RL Heath","year":"1968","unstructured":"Heath RL, Packer L: Photoperoxidation in isolated chloroplasts. I. Kinetics and stoichiometry of fatty acid peroxidation. Archieves of Biochemistry and Biophysics. 1968, 125: 189-198. 10.1016\/0003-9861(68)90654-1.","journal-title":"Archieves of Biochemistry and Biophysics"},{"key":"10099_CR51","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1111\/j.1469-8137.1994.tb03999.x","volume":"128","author":"J Patra","year":"1994","unstructured":"Patra J, Lenka M, Panda B: Tolerance and co-tolerance of the grass Chloris barbata Sw. to mercury, cadmium and zinc. New Phytol. 1994, 128: 165-171. 10.1111\/j.1469-8137.1994.tb03999.x.","journal-title":"New Phytol"},{"key":"10099_CR52","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/BF00018060","volume":"39","author":"LS Bates","year":"1973","unstructured":"Bates LS, Waldren RP, Teare ID: Rapid determination of free proline for water-stress studies. Plant Soil. 1973, 39: 205-207. 10.1007\/BF00018060.","journal-title":"Plant Soil"},{"key":"10099_CR53","doi-asserted-by":"crossref","first-page":"7130","DOI":"10.1016\/S0021-9258(19)42083-8","volume":"25","author":"WH Habig","year":"1974","unstructured":"Habig WH, Pabst MJ, Jakoby WB: Glutathione S-transferases: The first enzymatic step in mercapturic acid formation. Journal of Biological Chemistry. 1974, 25: 7130-7139.","journal-title":"Journal of Biological Chemistry"},{"key":"10099_CR54","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1073\/pnas.98.1.31","volume":"98","author":"C Li","year":"2001","unstructured":"Li C, Wang WH: Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. Proceedings of the National Academy of Sciences of the USA. 2001, 98: 31-36. 10.1073\/pnas.011404098.","journal-title":"Proceedings of the National Academy of Sciences of the USA"},{"key":"10099_CR55","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/1471-2105-8-87","volume":"8","author":"N Goffard","year":"2007","unstructured":"Goffard N, Weiller G: GeneBins: a database for classifying gene expression data: Application to plant genome arrays. BMC Bioinformatics. 2007, 8: 47-10.1186\/1471-2105-8-87.","journal-title":"BMC Bioinformatics"},{"key":"10099_CR56","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s11306-008-0130-6","volume":"4","author":"SK Bharti","year":"2008","unstructured":"Bharti SK, Sinha N, Joshi BS, Mandal SK, Roy R, Khetrapal CL: Improved Quantification from 1H-NMR Spectra Using Reduced Repetition Times. Metabolomics. 2008, 4: 367-376. 10.1007\/s11306-008-0130-6.","journal-title":"Metabolomics"},{"key":"10099_CR57","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1002\/mrc.1618","volume":"43","author":"AP Sobolev","year":"2005","unstructured":"Sobolev AP, Brosio E, Gianferri R, Segre A: Metabolic profile of lettuce leaves by high-field NMR spectra. Magn Reson Chem. 2005, 43: 625-638. 10.1002\/mrc.1618.","journal-title":"Magn Reson Chem"},{"key":"10099_CR58","first-page":"15","volume":"19","author":"BWK Diehl","year":"2007","unstructured":"Diehl BWK, Maiz F, Holzgrabe U: Quantitative NMR spectroscopy in the quality evaluation of active pharmaceutical in gredients and excipients. Spectroscopy Europe. 2007, 19: 15-19.","journal-title":"Spectroscopy Europe"}],"container-title":["BMC Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2164-11-648.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/1471-2164-11-648\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2164-11-648.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T06:51:14Z","timestamp":1630479074000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcgenomics.biomedcentral.com\/articles\/10.1186\/1471-2164-11-648"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11,20]]},"references-count":58,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["10099"],"URL":"https:\/\/doi.org\/10.1186\/1471-2164-11-648","relation":{},"ISSN":["1471-2164"],"issn-type":[{"value":"1471-2164","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,11,20]]},"assertion":[{"value":"25 May 2010","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 November 2010","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 November 2010","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"648"}}