{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T03:36:20Z","timestamp":1774928180091,"version":"3.50.1"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Genomics"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1186\/1471-2164-15-644","type":"journal-article","created":{"date-parts":[[2014,8,3]],"date-time":"2014-08-03T01:02:31Z","timestamp":1407027751000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Prediction of miRNA-mRNA associations in Alzheimer\u2019s disease mice using network topology"],"prefix":"10.1186","volume":"15","author":[{"given":"Haneul","family":"Noh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charny","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soojun","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Seek","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soo Young","family":"Cho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyemyung","family":"Seo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,8,3]]},"reference":[{"issue":"2","key":"6339_CR1","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/S0301-0082(99)00023-4","volume":"60","author":"JC Vickers","year":"2000","unstructured":"Vickers JC, Dickson TC, Adlard PA, Saunders HL, King CE, McCormack G: The cause of neuronal degeneration in Alzheimer\u2019s disease. Prog Neurobiol. 2000, 60 (2): 139-165.","journal-title":"Prog Neurobiol"},{"issue":"9","key":"6339_CR2","doi-asserted-by":"publisher","first-page":"1235","DOI":"10.1016\/j.neurobiolaging.2005.05.022","volume":"26","author":"GK Gouras","year":"2005","unstructured":"Gouras GK, Almeida CG, Takahashi RH: Intraneuronal A\u03b2 accumulation and origin of plaques in Alzheimer\u2019s disease. Neurobiol Aging. 2005, 26 (9): 1235-1244.","journal-title":"Neurobiol Aging"},{"issue":"Pt 3","key":"6339_CR3","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1042\/bj3230577","volume":"323","author":"ML Billingsley","year":"1997","unstructured":"Billingsley ML, Kincaid RL: Regulated phosphorylation and dephosphorylation of tau protein: effects on microtubule interaction, intracellular trafficking and neurodegeneration. Biochem J. 1997, 323 (Pt 3): 577-591.","journal-title":"Biochem J"},{"issue":"1","key":"6339_CR4","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.expneurol.2004.03.016","volume":"188","author":"C Schwab","year":"2004","unstructured":"Schwab C, Hosokawa M, McGeer PL: Transgenic mice overexpressing amyloid beta protein are an incomplete model of Alzheimer disease. Exp Neurol. 2004, 188 (1): 52-64.","journal-title":"Exp Neurol"},{"issue":"2","key":"6339_CR5","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1016\/j.expneurol.2011.09.003","volume":"235","author":"J Satoh","year":"2012","unstructured":"Satoh J: Molecular network of microRNA targets in Alzheimer\u2019s disease brains. Exp Neurol. 2012, 235 (2): 436-446.","journal-title":"Exp Neurol"},{"issue":"8","key":"6339_CR6","doi-asserted-by":"publisher","first-page":"1316","DOI":"10.1016\/j.biocel.2009.09.016","volume":"42","author":"K Breving","year":"2010","unstructured":"Breving K, Esquela-Kerscher A: The complexities of microRNA regulation: mirandering around the rules. Int J Biochem Cell Biol. 2010, 42 (8): 1316-1329.","journal-title":"Int J Biochem Cell Biol"},{"issue":"40","key":"6339_CR7","doi-asserted-by":"publisher","first-page":"10129","DOI":"10.1523\/JNEUROSCI.1202-06.2006","volume":"26","author":"H Oakley","year":"2006","unstructured":"Oakley H, Cole SL, Logan S, Maus E, Shao P, Craft J, Guillozet-Bongaarts A, Ohno M, Disterhoft J, Van Eldik L, Berry R, Vassar R: Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer\u2019s disease mutations: potential factors in amyloid plaque formation. J Neurosci. 2006, 26 (40): 10129-10140.","journal-title":"J Neurosci"},{"issue":"11","key":"6339_CR8","doi-asserted-by":"publisher","first-page":"1671","DOI":"10.1016\/j.bbadis.2012.07.004","volume":"1822","author":"VM Vitvitsky","year":"2012","unstructured":"Vitvitsky VM, Garg SK, Keep RF, Albin RL, Banerjee R: Na\u2009+\u2009and K\u2009+\u2009ion imbalances in Alzheimer\u2019s disease. Biochim Biophys Acta. 2012, 1822 (11): 1671-1681.","journal-title":"Biochim Biophys Acta"},{"issue":"2","key":"6339_CR9","first-page":"107","volume":"38","author":"GJ Brewer","year":"2012","unstructured":"Brewer GJ: Copper excess, zinc deficiency, and cognition loss in Alzheimer\u2019s disease. Bio factors. 2012, 38 (2): 107-113.","journal-title":"Bio factors"},{"issue":"4","key":"6339_CR10","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/j.jtemb.2011.08.144","volume":"25","author":"AB Bowman","year":"2011","unstructured":"Bowman AB, Kwakye GF, Herrero Hern\u00e1ndez E, Aschner M: Role of manganese in neurodegenerative diseases. J Trace Elem Med Biol. 2011, 25 (4): 191-203.","journal-title":"J Trace Elem Med Biol"},{"issue":"7","key":"6339_CR11","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1016\/j.tips.2009.05.002","volume":"30","author":"P Zatta","year":"2009","unstructured":"Zatta P, Drago D, Bolognin S, Sensi SL: Alzheimer\u2019s disease, metal ions and metal homeostatic therapy. Trends Pharmacol Sci. 2009, 30 (7): 346-355.","journal-title":"Trends Pharmacol Sci"},{"issue":"17","key":"6339_CR12","doi-asserted-by":"publisher","first-page":"13107","DOI":"10.1074\/jbc.M110.100420","volume":"285","author":"A Caccamo","year":"2010","unstructured":"Caccamo A, Majumder S, Richardson A, Strong R, Oddo S: Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments. J Biol Chem. 2010, 285 (17): 13107-13120.","journal-title":"J Biol Chem"},{"issue":"8","key":"6339_CR13","doi-asserted-by":"crossref","first-page":"2661","DOI":"10.1523\/JNEUROSCI.21-08-02661.2001","volume":"21","author":"Y Yang","year":"2001","unstructured":"Yang Y, Geldmacher DS, Herrup K: DNA replication precedes neuronal cell death in Alzheimer\u2019s disease. J Neurosci. 2001, 21 (8): 2661-2668.","journal-title":"J Neurosci"},{"issue":"5","key":"6339_CR14","doi-asserted-by":"publisher","first-page":"1598","DOI":"10.2353\/ajpath.2006.050840","volume":"168","author":"TL Spires","year":"2006","unstructured":"Spires TL, Orne JD, SantaCruz K, Pitstick R, Carlson GA, Ashe KH, Hyman BT: Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy. Am J Pathol. 2006, 168 (5): 1598-1607.","journal-title":"Am J Pathol"},{"issue":"2","key":"6339_CR15","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1172\/JCI30070","volume":"117","author":"FA High","year":"2007","unstructured":"High FA, Zhang M, Proweller A, Tu L, Parmacek MS, Pear WS, Epstein JA: An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation. J Clin Invest. 2007, 117 (2): 353-363.","journal-title":"J Clin Invest"},{"issue":"4","key":"6339_CR16","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1016\/j.bbrc.2009.10.093","volume":"390","author":"HN Woo","year":"2009","unstructured":"Woo HN, Park JS, Gwon AR, Arumugam TV, Jo DG: Alzheimer\u2019s disease and Notch signaling. Biochem Biophys Res Commun. 2009, 390 (4): 1093-1097.","journal-title":"Biochem Biophys Res Commun"},{"issue":"2","key":"6339_CR17","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/S1534-5807(02)00121-1","volume":"2","author":"EE Wanker","year":"2002","unstructured":"Wanker EE: Hip1 and Hippi participate in a novel cell death-signaling pathway. Dev Cell. 2002, 2 (2): 126-128.","journal-title":"Dev Cell"},{"issue":"20","key":"6339_CR18","doi-asserted-by":"publisher","first-page":"4299","DOI":"10.1038\/emboj.2011.327","volume":"30","author":"A Zovoilis","year":"2011","unstructured":"Zovoilis A, Agbemenyah HY, Agis-Balboa RC, Stilling RM, Edbauer D, Rao P, Farinelli L, Delalle I, Schmitt A, Falkai P, Burkhardt S, Sanabenesi F, Fischer A: microRNA-34c is a novel target to treat dementias. EMBO J. 2011, 30 (20): 4299-4308.","journal-title":"EMBO J"},{"issue":"11","key":"6339_CR19","doi-asserted-by":"publisher","first-page":"2225","DOI":"10.1093\/hmg\/ddr111","volume":"20","author":"PM Gaughwin","year":"2011","unstructured":"Gaughwin PM, Ciesla M, Lahiri N, Tabrizi SJ, Brundin P, Bjorkqvist M: Hsa-miR-34b is a plasma-stable microRNA that is elevated in pre-manifest Huntington\u2019s disease. Hum Mol Genet. 2011, 20 (11): 2225-2237.","journal-title":"Hum Mol Genet"},{"issue":"15","key":"6339_CR20","doi-asserted-by":"publisher","first-page":"3067","DOI":"10.1093\/hmg\/ddr210","volume":"20","author":"E Minones-Moyano","year":"2011","unstructured":"Minones-Moyano E, Porta S, Escaramis G, Rabionet R, Iraola S, Kagerbauer B, Espinosa-Parrilla Y, Ferrer I, Estivill X, Marti E: MicroRNA profiling of Parkinson\u2019s disease brains identifies early downregulation of miR-34b\/c which modulate mitochondrial function. Hum Mol Genet. 2011, 20 (15): 3067-3078.","journal-title":"Hum Mol Genet"},{"issue":"1","key":"6339_CR21","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3233\/JAD-2008-14103","volume":"14","author":"JP Cogswell","year":"2008","unstructured":"Cogswell JP, Ward J, Taylor IA, Waters M, Shi Y, Cannon B, Kelnar K, Kemppainen J, Brown D, Chen C, Prinjha RK, Richardson JC, Saunders AM, Roses AD, Richards CA: Identification of miRNA changes in Alzheimer\u2019s disease brain and CSF yields putative biomarkers and insights into disease pathways. J Alzheimers Dis. 2008, 14 (1): 27-41.","journal-title":"J Alzheimers Dis"},{"issue":"6","key":"6339_CR22","doi-asserted-by":"publisher","first-page":"2481","DOI":"10.1523\/JNEUROSCI.4440-12.2013","volume":"33","author":"D Gomez-Nicola","year":"2013","unstructured":"Gomez-Nicola D, Fransen NL, Suzzi S, Perry VH: Regulation of microglial proliferation during chronic neurodegeneration. J Neurosci. 2013, 33 (6): 2481-2493.","journal-title":"J Neurosci"},{"issue":"3","key":"6339_CR23","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1097\/01.jnen.0000202887.22082.63","volume":"65","author":"JR Conde","year":"2006","unstructured":"Conde JR, Streit WJ: Microglia in the aging brain. J Neuropathol Exp Neurol. 2006, 65 (3): 199-203.","journal-title":"J Neuropathol Exp Neurol"},{"issue":"7386","key":"6339_CR24","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1038\/nature10810","volume":"482","author":"N Liu","year":"2012","unstructured":"Liu N, Landreh M, Cao K, Abe M, Hendriks GJ, Kennerdell JR, Zhu Y, Wang LS, Bonini NM: The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila. Nature. 2012, 482 (7386): 519-523.","journal-title":"Nature"},{"issue":"4","key":"6339_CR25","doi-asserted-by":"publisher","first-page":"1186","DOI":"10.1182\/blood-2002-12-3775","volume":"102","author":"C Hundhausen","year":"2003","unstructured":"Hundhausen C, Misztela D, Berkhout TA, Broadway N, Saftig P, Reiss K, Hartmann D, Fahrenholz F, Postina R, Matthews V, Kallen KJ, Rose-John S, Ludwig A: The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion. Blood. 2003, 102 (4): 1186-1195.","journal-title":"Blood"},{"issue":"2","key":"6339_CR26","first-page":"167","volume":"61","author":"T Yokota","year":"2009","unstructured":"Yokota T: [MicroRNA and central nervous system]. Brain and Nerve \/ No to Shinkei. 2009, 61 (2): 167-176.","journal-title":"Brain and Nerve \/ No to Shinkei"},{"issue":"6","key":"6339_CR27","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1038\/emboj.2009.10","volume":"28","author":"R Fiore","year":"2009","unstructured":"Fiore R, Khudayberdiev S, Christensen M, Siegel G, Flavell SW, Kim TK, Greenberg ME, Schratt G: Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels. EMBO J. 2009, 28 (6): 697-710.","journal-title":"EMBO J"},{"issue":"2\u20133","key":"6339_CR28","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.lfs.2003.09.003","volume":"74","author":"H Kurose","year":"2003","unstructured":"Kurose H: Galpha12 and Galpha13 as key regulatory mediator in signal transduction. Life Sci. 2003, 74 (2\u20133): 155-161.","journal-title":"Life Sci"},{"issue":"1","key":"6339_CR29","doi-asserted-by":"publisher","first-page":"e14494","DOI":"10.1371\/journal.pone.0014494","volume":"6","author":"A Podolska","year":"2011","unstructured":"Podolska A, Kaczkowski B, Kamp Busk P, Sokilde R, Litman T, Fredholm M, Cirera S: MicroRNA expression profiling of the porcine developing brain. PLoS One. 2011, 6 (1): e14494-","journal-title":"PLoS One"},{"issue":"1","key":"6339_CR30","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1158\/0008-5472.CAN-10-1850","volume":"71","author":"J Lu","year":"2011","unstructured":"Lu J, He ML, Wang L, Chen Y, Liu X, Dong Q, Chen YC, Peng Y, Yao KT, Kung HF, Li XP: MiR-26a inhibits cell growth and tumorigenesis of nasopharyngeal carcinoma through repression of EZH2. Cancer Res. 2011, 71 (1): 225-233.","journal-title":"Cancer Res"},{"issue":"36","key":"6339_CR31","doi-asserted-by":"publisher","first-page":"5032","DOI":"10.1038\/onc.2010.250","volume":"29","author":"KM Draheim","year":"2010","unstructured":"Draheim KM, Chen HB, Tao Q, Moore N, Roche M, Lyle S: ARRDC3 suppresses breast cancer progression by negatively regulating integrin beta4. Oncogene. 2010, 29 (36): 5032-5047.","journal-title":"Oncogene"},{"issue":"37","key":"6339_CR32","doi-asserted-by":"publisher","first-page":"24996","DOI":"10.1074\/jbc.M109.018093","volume":"284","author":"P Patwari","year":"2009","unstructured":"Patwari P, Chutkow WA, Cummings K, Verstraeten VL, Lammerding J, Schreiter ER, Lee RT: Thioredoxin-independent regulation of metabolism by the alpha-arrestin proteins. J Biol Chem. 2009, 284 (37): 24996-25003.","journal-title":"J Biol Chem"},{"issue":"5","key":"6339_CR33","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1016\/j.cmet.2011.08.011","volume":"14","author":"P Patwari","year":"2011","unstructured":"Patwari P, Emilsson V, Schadt EE, Chutkow WA, Lee S, Marsili A, Zhang Y, Dobrin R, Cohen DE, Larsen PR, Zavacki AM, Fong LG, Young SG, Lee RT: The arrestin domain-containing 3 protein regulates body mass and energy expenditure. Cell Metab. 2011, 14 (5): 671-683.","journal-title":"Cell Metab"},{"issue":"4","key":"6339_CR34","doi-asserted-by":"publisher","first-page":"e35678","DOI":"10.1371\/journal.pone.0035678","volume":"7","author":"YD Ke","year":"2012","unstructured":"Ke YD, Dramiga J, Schutz U, Kril JJ, Ittner LM, Schroder H, Gotz J: Tau-mediated nuclear depletion and cytoplasmic accumulation of SFPQ in Alzheimer\u2019s and Pick\u2019s disease. PLoS One. 2012, 7 (4): e35678-","journal-title":"PLoS One"},{"issue":"20","key":"6339_CR35","doi-asserted-by":"publisher","first-page":"4366","DOI":"10.1016\/j.febslet.2010.09.040","volume":"584","author":"GM Shen","year":"2010","unstructured":"Shen GM, Zhang FL, Liu XL, Zhang JW: Hypoxia-inducible factor 1-mediated regulation of PPP1R3C promotes glycogen accumulation in human MCF-7 cells under hypoxia. FEBS Lett. 2010, 584 (20): 4366-4372.","journal-title":"FEBS Lett"},{"issue":"9","key":"6339_CR36","doi-asserted-by":"publisher","first-page":"4025","DOI":"10.1093\/nar\/gkr1289","volume":"40","author":"C Sumanasekera","year":"2012","unstructured":"Sumanasekera C, Kelemen O, Beullens M, Aubol BE, Adams JA, Sunkara M, Morris A, Bollen M, Andreadis A, Stamm S: C6 pyridinium ceramide influences alternative pre-mRNA splicing by inhibiting protein phosphatase-1. Nucleic Acids Res. 2012, 40 (9): 4025-4039.","journal-title":"Nucleic Acids Res"},{"issue":"3","key":"6339_CR37","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1016\/j.neurobiolaging.2006.10.012","volume":"29","author":"ER Bychkov","year":"2008","unstructured":"Bychkov ER, Gurevich VV, Joyce JN, Benovic JL, Gurevich EV: Arrestins and two receptor kinases are upregulated in Parkinson\u2019s disease with dementia. Neurobiol Aging. 2008, 29 (3): 379-396.","journal-title":"Neurobiol Aging"},{"issue":"2","key":"6339_CR38","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1038\/nrneurol.2012.278","volume":"9","author":"H Wood","year":"2013","unstructured":"Wood H: Alzheimer disease: Arrestin\u2019 Alzheimer disease progression? [beta]-arrestin 2 is a potential therapeutic target. Nat Rev Neurol. 2013, 9 (2): 60-","journal-title":"Nat Rev Neurol"},{"issue":"1","key":"6339_CR39","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1038\/nm.3023","volume":"19","author":"A Thathiah","year":"2013","unstructured":"Thathiah A, Horre K, Snellinx A, Vandewyer E, Huang Y, Ciesielska M, De Kloe G, Munck S, De Strooper B: [beta]-arrestin 2 regulates A [beta] generation and [gamma]-secretase activity in Alzheimer\u2019s disease. Nat Med. 2013, 19 (1): 43-49.","journal-title":"Nat Med"},{"issue":"33","key":"6339_CR40","doi-asserted-by":"publisher","first-page":"3996","DOI":"10.2174\/092986710793205363","volume":"17","author":"M Fardilha","year":"2010","unstructured":"Fardilha M, Esteves SL, Korrodi-Gregorio L, da Cruz-e Silva OA, da Cruz-e Silva FF: The physiological relevance of protein phosphatase 1 and its interacting proteins to health and disease. Curr Med Chem. 2010, 17 (33): 3996-4017.","journal-title":"Curr Med Chem"},{"issue":"3","key":"6339_CR41","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1093\/bioinformatics\/btg405","volume":"20","author":"L Gautier","year":"2004","unstructured":"Gautier L, Cope L, Bolstad BM, Irizarry RA: affy\u2013analysis of Affymetrix GeneChip data at the probe level. Bioinformatics. 2004, 20 (3): 307-315.","journal-title":"Bioinformatics"},{"issue":"4","key":"6339_CR42","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1038\/nmeth.1923","volume":"9","author":"B Langmead","year":"2012","unstructured":"Langmead B, Salzberg SL: Fast gapped-read alignment with Bowtie 2. Nat Methods. 2012, 9 (4): 357-359.","journal-title":"Nat Methods"},{"issue":"Database issue","key":"6339_CR43","doi-asserted-by":"publisher","first-page":"D152","DOI":"10.1093\/nar\/gkq1027","volume":"39","author":"A Kozomara","year":"2011","unstructured":"Kozomara A, Griffiths-Jones S: miRBase: integrating microRNA annotation and deep-sequencing data. Nucleic Acids Res. 2011, 39 (Database issue): D152-D157.","journal-title":"Nucleic Acids Res"},{"key":"6339_CR44","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1186\/1471-2105-9-559","volume":"9","author":"P Langfelder","year":"2008","unstructured":"Langfelder P, Horvath S: WGCNA: an R package for weighted correlation network analysis. BMC Bioinformatics. 2008, 9: 559-","journal-title":"BMC Bioinformatics"},{"issue":"1","key":"6339_CR45","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1038\/nprot.2008.211","volume":"4","author":"W da Huang","year":"2009","unstructured":"da Huang W, Sherman BT, Lempicki RA: Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc. 2009, 4 (1): 44-57.","journal-title":"Nat Protoc"},{"issue":"Database issue","key":"6339_CR46","first-page":"D149","volume":"36","author":"D Betel","year":"2008","unstructured":"Betel D, Wilson M, Gabow A, Marks DS, Sander C: The microRNA.org resource: targets and expression. Nucleic Acids Res. 2008, 36 (Database issue): D149-D153.","journal-title":"Nucleic Acids Res"},{"issue":"10","key":"6339_CR47","doi-asserted-by":"publisher","first-page":"1139","DOI":"10.1038\/nsmb.2115","volume":"18","author":"DM Garcia","year":"2011","unstructured":"Garcia DM, Baek D, Shin C, Bell GW, Grimson A, Bartel DP: Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs. Nat Struct Mol Biol. 2011, 18 (10): 1139-1146.","journal-title":"Nat Struct Mol Biol"},{"issue":"1\u20137","key":"6339_CR48","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/S0169-7552(98)00110-X","volume":"30","author":"S Brin","year":"1998","unstructured":"Brin S, Page L: The anatomy of a large-scale hypertextual Web search engine. Comput Networks Isdn. 1998, 30 (1\u20137): 107-117.","journal-title":"Comput Networks Isdn"},{"issue":"2","key":"6339_CR49","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1016\/j.expneurol.2004.11.017","volume":"193","author":"H Seo","year":"2005","unstructured":"Seo H, Isacson O: Abnormal APP, cholinergic and cognitive function in Ts65Dn Down\u2019s model mice. Exp Neurol. 2005, 193 (2): 469-480.","journal-title":"Exp Neurol"},{"key":"6339_CR50","doi-asserted-by":"publisher","first-page":"3846","DOI":"10.1038\/srep03846","volume":"4","author":"YH Soung","year":"2014","unstructured":"Soung YH, Pruitt K, Chung J: Epigenetic silencing of ARRDC3 expression in basal-like breast cancer cells. Sci Rep. 2014, 4: 3846-","journal-title":"Sci Rep"}],"container-title":["BMC Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2164-15-644.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T05:21:28Z","timestamp":1630560088000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcgenomics.biomedcentral.com\/articles\/10.1186\/1471-2164-15-644"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8,3]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["6339"],"URL":"https:\/\/doi.org\/10.1186\/1471-2164-15-644","relation":{},"ISSN":["1471-2164"],"issn-type":[{"value":"1471-2164","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,8,3]]},"assertion":[{"value":"23 January 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 July 2014","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 August 2014","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"644"}}