{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T00:09:50Z","timestamp":1792714190536,"version":"4.5.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Microbiol"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Capsular serotypes K1 and K2 of <jats:italic>Klebsiella pneumoniae<\/jats:italic> are thought to the major virulence determinants responsible for liver abscess. The intestine is one of the major reservoirs of <jats:italic>K. pneumoniae<\/jats:italic>, and epidemiological studies have suggested that the majority of <jats:italic>K. pneumoniae<\/jats:italic> infections are preceded by colonization of the gastrointestinal tract. The possibility of fecal-oral transmission in liver abscess has been raised on the basis of molecular typing of isolates. Data on the serotype distribution of <jats:italic>K. pneumoniae<\/jats:italic> in stool samples from healthy individuals has not been previously reported. This study investigated the seroepidemiology of <jats:italic>K. pneumoniae<\/jats:italic> isolates from the intestinal tract of healthy Chinese in Asian countries. Stool specimens from healthy adult Chinese residents of Taiwan, Japan, Hong Kong, China, Thailand, Malaysia, Singapore, and Vietnam were collected from August 2004 to August 2010 for analysis.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Serotypes K1\/K2 accounted for 9.8% of all <jats:italic>K. pneumoniae<\/jats:italic> isolates from stools in all countries. There was no significant difference in the prevalence of K1\/K2 isolates among the countries excluding Thailand and Vietnam. The antimicrobial susceptibility pattern was nearly the same in <jats:italic>K. pneumoniae<\/jats:italic> isolates. The result of pulsed-field gel electrophoresis revealed no major clonal cluster of serotype K1 isolates.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>The result showed that Chinese ethnicity itself might be a major factor predisposing to intestinal colonization by serotype K1\/K2 <jats:italic>K. pneumoniae<\/jats:italic> isolates. The prevalent serotype K1\/K2 isolates may partially correspond to the prevalence of <jats:italic>K. pneumoniae<\/jats:italic> liver abscess in Asian countries.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1471-2180-12-13","type":"journal-article","created":{"date-parts":[[2012,1,19]],"date-time":"2012-01-19T19:28:58Z","timestamp":1327001338000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":169,"title":["Seroepidemiology of Klebsiella pneumoniae colonizing the intestinal tract of healthy chinese and overseas chinese adults in Asian countries"],"prefix":"10.1186","volume":"12","author":[{"given":"Yi-Tsung","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L Kristopher","family":"Siu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung-Chung","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Te-Li","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Peng","family":"Tseng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuo-Ming","family":"Yeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng-Yee","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-Phone","family":"Fung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,1,19]]},"reference":[{"key":"1571_CR1","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1128\/CMR.11.4.589","volume":"11","author":"R Podschun","year":"1998","unstructured":"Podschun R, Ullmann U: Klebsiellspp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors. 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