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In this study we use multilocus variable number of tandem repeats (VNTRs) analysis (MLVA) to discriminate between isolates of the 7th pandemic clone of <jats:italic>Vibrio cholerae.<\/jats:italic>\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>MLVA of six VNTRs selected from previously published data distinguished 66 <jats:italic>V. cholerae<\/jats:italic> isolates collected between 1961\u20131999 into 60 unique MLVA profiles. Only 4 MLVA profiles consisted of more than 2 isolates. The discriminatory power was 0.995. Phylogenetic analysis showed that, except for the closely related profiles, the relationships derived from MLVA profiles were in conflict with that inferred from Single Nucleotide Polymorphism (SNP) typing. The six SNP groups share consensus VNTR patterns and two SNP groups contained isolates which differed by only one VNTR locus.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>MLVA is highly discriminatory in differentiating 7th pandemic <jats:italic>V. cholerae<\/jats:italic> isolates and MLVA data was most useful in resolving the genetic relationships among isolates within groups previously defined by SNPs. Thus MLVA is best used in conjunction with SNP typing in order to best determine the evolutionary relationships among the 7th pandemic <jats:italic>V. cholerae<\/jats:italic> isolates and for longer term epidemiological typing.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1471-2180-12-82","type":"journal-article","created":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T11:26:29Z","timestamp":1338549989000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Multi-locus variable number tandem repeat analysis of 7th pandemic Vibrio cholerae"],"prefix":"10.1186","volume":"12","author":[{"given":"Connie","family":"Lam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Octavia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter R","family":"Reeves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruiting","family":"Lan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,5,24]]},"reference":[{"key":"1675_CR1","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.bbadis.2003.08.004","volume":"1639","author":"SN Chatterjee","year":"2003","unstructured":"Chatterjee SN, Chaudhuri K: Lipopolysaccharides ofVibrio cholerae. 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