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To date, the use of a phage to prevent infections caused by MDRAB has not been demonstrated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The MDRAB-specific phage \u03d5AB2 was stable at 4\u00b0C and pH 7 in 0.5% chloroform solution, and showed a slight decrease in plaque-forming units (PFU)\/ml of 0.3\u20130.9 log after 330 days of storage. The addition of \u03d5AB2 at a concentration of at least 10<jats:sup>5<\/jats:sup>PFU\/ml to an<jats:italic>A. baumannii<\/jats:italic>M3237 suspension killed &gt;99.9% of<jats:italic>A. baumannii<\/jats:italic>M3237 after 5 min, regardless of<jats:italic>A. baumannii<\/jats:italic>M3237 concentration (10<jats:sup>4<\/jats:sup>, 10<jats:sup>5<\/jats:sup>, or 10<jats:sup>6<\/jats:sup>colony-forming units (CFU)\/ml). The addition of \u03d5AB2 at a concentration of 10<jats:sup>8<\/jats:sup>PFU\/slide (&gt;10<jats:sup>7<\/jats:sup>PFU\/cm<jats:sup>2<\/jats:sup>) to glass slides containing<jats:italic>A. baumannii<\/jats:italic>M3237 at 10<jats:sup>4<\/jats:sup>, 10<jats:sup>5<\/jats:sup>, or 10<jats:sup>6<\/jats:sup>CFU\/slide, significantly reduced bacterial numbers by 93%, 97%, and 99%, respectively. Thus, this concentration is recommended for decontamination of glass surfaces. Moreover, infusion of \u03d5AB2 into 10% glycerol exhibited strong anti-MDRAB activity (99.9% reduction), even after 90 days of storage. Treatment of a 10% paraffin oil-based lotion with \u03d5AB2 significantly reduced (99%)<jats:italic>A. baumannii<\/jats:italic>M3237 after 1 day of storage. However, \u03d5AB2 had no activity in the lotion after 1 month of storage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Phages may be useful for reducing MDRAB contamination in liquid suspensions or on hard surfaces. Phages may also be inoculated into a solution to produce an antiseptic hand wash. 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