{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T06:02:02Z","timestamp":1792735322433,"version":"4.5.0"},"reference-count":64,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Neurosci"],"published-print":{"date-parts":[[2010,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Mesial temporal lobe epilepsy (MTLE), the most common type of focal epilepsy in adults, is often caused by hippocampal sclerosis (HS). Patients with HS usually present memory dysfunction, which is material-specific according to the hemisphere involved and has been correlated to the degree of HS as measured by postoperative histopathology as well as by the degree of hippocampal atrophy on magnetic resonance imaging (MRI). Verbal memory is mostly affected by left-sided HS, whereas visuo-spatial memory is more affected by right HS. Some of these impairments may be related to abnormalities of the network in which individual hippocampus takes part. Functional connectivity can play an important role to understand how the hippocampi interact with other brain areas. It can be estimated via functional Magnetic Resonance Imaging (fMRI) resting state experiments by evaluating patterns of functional networks. In this study, we investigated the functional connectivity patterns of 9 control subjects, 9 patients with right MTLE and 9 patients with left MTLE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We detected differences in functional connectivity within and between hippocampi in patients with unilateral MTLE associated with ipsilateral HS by resting state fMRI. Functional connectivity resulted to be more impaired ipsilateral to the seizure focus in both patient groups when compared to control subjects. This effect was even more pronounced for the left MTLE group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The findings presented here suggest that left HS causes more reduction of functional connectivity than right HS in subjects with left hemisphere dominance for language.<\/jats:p><\/jats:sec>","DOI":"10.1186\/1471-2202-11-66","type":"journal-article","created":{"date-parts":[[2010,6,2]],"date-time":"2010-06-02T18:15:23Z","timestamp":1275502523000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":185,"title":["Asymmetrical hippocampal connectivity in mesial temporal lobe epilepsy: evidence from resting state fMRI"],"prefix":"10.1186","volume":"11","author":[{"given":"Fabr\u00edcio RS","family":"Pereira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9a","family":"Alessio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maur\u00edcio S","family":"Sercheli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiane","family":"Pedro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Bilevicius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane M","family":"Rondina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helka FB","family":"Ozelo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela","family":"Castellano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto JM","family":"Covolan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benito P","family":"Damasceno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Cendes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,6,2]]},"reference":[{"key":"1625_CR1","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1097\/WCO.0b013e3282f36ccd","volume":"21","author":"AT Berg","year":"2008","unstructured":"Berg AT: The natural history of mesial temporal lobe epilepsy. Curr Opin Neurol. 2008, 21: 173-178. 10.1097\/WCO.0b013e3282f36ccd.","journal-title":"Curr Opin Neurol"},{"key":"1625_CR2","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1097\/01.wco.0000162860.49842.90","volume":"18","author":"F Cendes","year":"2005","unstructured":"Cendes F: Progressive hippocampal and extrahippocampal atrophy in drug resistant epilepsy. Curr Opin Neurol. 2005, 18: 173-177. 10.1097\/01.wco.0000162860.49842.90.","journal-title":"Curr Opin Neurol"},{"key":"1625_CR3","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1111\/j.0013-9580.2004.09004.x","volume":"45","author":"HG Wieser","year":"2004","unstructured":"Wieser HG: ILAE Commission Report. Mesial temporal lobe epilepsy with hippocampal sclerosis. Epilepsia. 2004, 45: 695-714. 10.1111\/j.0013-9580.2004.09004.x.","journal-title":"Epilepsia"},{"key":"1625_CR4","first-page":"735","volume":"32","author":"A Aertsen","year":"1991","unstructured":"Aertsen A, Vaadia E, Abeles M, Ahissar E, Bergman H, Karmon B, Lavner Y, Margalit E, Nelken I, Rotter S: Neural interactions in the frontal cortex of a behaving monkey: signs of dependence on stimulus context and behavioral state. J Hirnforsch. 1991, 32: 735-743.","journal-title":"J Hirnforsch"},{"key":"1625_CR5","doi-asserted-by":"publisher","first-page":"1379","DOI":"10.1001\/archneur.61.9.1379","volume":"61","author":"L Bonilha","year":"2004","unstructured":"Bonilha L, Rorden C, Castellano G, Pereira F, Rio PA, Cendes F, Li LM: Voxel-based morphometry reveals gray matter network atrophy in refractory medial temporal lobe epilepsy. Arch Neurol. 2004, 61: 1379-1384. 10.1001\/archneur.61.9.1379.","journal-title":"Arch Neurol"},{"key":"1625_CR6","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.yebeh.2003.10.010","volume":"5","author":"A Alessio","year":"2004","unstructured":"Alessio A, Damasceno BP, Camargo CH, Kobayashi E, Guerreiro CA, Cendes F: Differences in memory performance and other clinical characteristics in patients with mesial temporal lobe epilepsy with and without hippocampal atrophy. Epilepsy Behav. 2004, 5: 22-27. 10.1016\/j.yebeh.2003.10.010.","journal-title":"Epilepsy Behav"},{"key":"1625_CR7","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/S0010-9452(80)80026-8","volume":"16","author":"RC Delaney","year":"1980","unstructured":"Delaney RC, Rosen AJ, Mattson RH, Novelly RA: Memory function in focal epilepsy: a comparison of non-surgical, unilateral temporal lobe and frontal lobe samples. Cortex. 1980, 16: 103-117.","journal-title":"Cortex"},{"key":"1625_CR8","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1037\/0894-4105.17.4.556","volume":"17","author":"H Kim","year":"2003","unstructured":"Kim H, Yi S, Son EI, Kim J: Differential effects of left versus right mesial temporal lobe epilepsy on Wechsler intelligence factors. Neuropsychology. 2003, 17: 556-565. 10.1037\/0894-4105.17.4.556.","journal-title":"Neuropsychology"},{"key":"1625_CR9","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/S0920-1211(96)00043-5","volume":"26","author":"J Engel","year":"1996","unstructured":"Engel J: Introduction to temporal lobe epilepsy. Epilepsy Res. 1996, 26: 141-150. 10.1016\/S0920-1211(96)00043-5.","journal-title":"Epilepsy Res"},{"key":"1625_CR10","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1007\/BF00231248","volume":"82","author":"CL Wilson","year":"1990","unstructured":"Wilson CL, Isokawa M, Babb TL, Crandall PH: Functional connections in the human temporal lobe. I. Analysis of limbic system pathways using neuronal responses evoked by electrical stimulation. Exp Brain Res. 1990, 82: 279-292. 10.1007\/BF00231248.","journal-title":"Exp Brain Res"},{"key":"1625_CR11","doi-asserted-by":"publisher","first-page":"1746","DOI":"10.1016\/S1388-2457(01)00591-0","volume":"112","author":"F Bartolomei","year":"2001","unstructured":"Bartolomei F, Wendling F, Bellanger JJ, Regis J, Chauvel P: Neural networks involving the medial temporal structures in temporal lobe epilepsy. Clin Neurophysiol. 2001, 112: 1746-1760. 10.1016\/S1388-2457(01)00591-0.","journal-title":"Clin Neurophysiol"},{"key":"1625_CR12","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1046\/j.1528-1157.2002.26901.x","volume":"43","author":"SS Spencer","year":"2002","unstructured":"Spencer SS: Neural networks in human epilepsy: evidence of and implications for treatment. Epilepsia. 2002, 43: 219-227. 10.1046\/j.1528-1157.2002.26901.x.","journal-title":"Epilepsia"},{"key":"1625_CR13","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1016\/j.neuroimage.2007.12.031","volume":"40","author":"NK Focke","year":"2008","unstructured":"Focke NK, Yogarajah M, Bonelli SB, Bartlett PA, Symms MR, Duncan JS: Voxel-based diffusion tensor imaging in patients with mesial temporal lobe epilepsy and hippocampal sclerosis. Neuroimage. 2008, 40: 728-737. 10.1016\/j.neuroimage.2007.12.031.","journal-title":"Neuroimage"},{"key":"1625_CR14","doi-asserted-by":"publisher","first-page":"1755","DOI":"10.1016\/j.neuroimage.2007.12.046","volume":"40","author":"M Yogarajah","year":"2008","unstructured":"Yogarajah M, Powell HW, Parker GJ, Alexander DC, Thompson PJ, Symms MR, Boulby P, Wheeler-Kingshott CA, Barker GJ, Koepp MJ, Duncan JS: Tractography of the parahippocampal gyrus and material specific memory impairment in unilateral temporal lobe epilepsy. Neuroimage. 2008, 40: 1755-1764. 10.1016\/j.neuroimage.2007.12.046.","journal-title":"Neuroimage"},{"key":"1625_CR15","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1002\/hbm.460020107","volume":"2","author":"K Friston","year":"1994","unstructured":"Friston K: Functional and effective connectivity in neuroimaging: A synthesis. Human Brain Mapping. 1994, 2: 56-78. 10.1002\/hbm.460020107.","journal-title":"Human Brain Mapping"},{"key":"1625_CR16","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1038\/nn2017","volume":"11","author":"MT Colonnese","year":"2008","unstructured":"Colonnese MT, Phillips MA, Constantine-Paton M, Kaila K, Jasanoff A: Development of hemodynamic responses and functional connectivity in rat somatosensory cortex. Nat Neurosci. 2008, 11: 72-79. 10.1038\/nn2017.","journal-title":"Nat Neurosci"},{"key":"1625_CR17","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1038\/nn.2232","volume":"12","author":"I Nauhaus","year":"2009","unstructured":"Nauhaus I, Busse L, Carandini M, Ringach DL: Stimulus contrast modulates functional connectivity in visual cortex. Nat Neurosci. 2009, 12: 70-76. 10.1038\/nn.2232.","journal-title":"Nat Neurosci"},{"key":"1625_CR18","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1038\/jcbfm.1993.4","volume":"13","author":"KJ Friston","year":"1993","unstructured":"Friston KJ, Frith CD, Liddle PF, Frackowiak RS: Functional connectivity: the principal-component analysis of large (PET) data sets. J Cereb Blood Flow Metab. 1993, 13: 5-14.","journal-title":"J Cereb Blood Flow Metab"},{"key":"1625_CR19","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1111\/j.1528-1167.2006.00895.x","volume":"48","author":"WN Loscher","year":"2007","unstructured":"Loscher WN, Dobesberger J, Szubski C, Trinka E: rTMS reveals premotor cortex dysfunction in frontal lobe epilepsy. Epilepsia. 2007, 48: 359-365. 10.1111\/j.1528-1167.2006.00895.x.","journal-title":"Epilepsia"},{"key":"1625_CR20","doi-asserted-by":"publisher","first-page":"2316","DOI":"10.1093\/brain\/awh246","volume":"127","author":"R Matsumoto","year":"2004","unstructured":"Matsumoto R, Nair DR, LaPresto E, Najm I, Bingaman W, Shibasaki H, Luders HO: Functional connectivity in the human language system: a cortico-cortical evoked potential study. Brain. 2004, 127: 2316-2330. 10.1093\/brain\/awh246.","journal-title":"Brain"},{"key":"1625_CR21","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1177\/155005949002100114","volume":"21","author":"J Montplaisir","year":"1990","unstructured":"Montplaisir J, Nielsen T, Cote J, Boivin D, Rouleau I, Lapierre G: Interhemispheric EEG coherence before and after partial callosotomy. Clin Electroencephalogr. 1990, 21: 42-47.","journal-title":"Clin Electroencephalogr"},{"key":"1625_CR22","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1002\/(SICI)1099-1492(199706\/08)10:4\/5<165::AID-NBM454>3.0.CO;2-7","volume":"10","author":"BB Biswal","year":"1997","unstructured":"Biswal BB, Van Kylen J, Hyde JS: Simultaneous assessment of flow and BOLD signals in resting-state functional connectivity maps. NMR Biomed. 1997, 10: 165-170. 10.1002\/(SICI)1099-1492(199706\/08)10:4\/5<165::AID-NBM454>3.0.CO;2-7.","journal-title":"NMR Biomed"},{"key":"1625_CR23","doi-asserted-by":"publisher","first-page":"3517","DOI":"10.1152\/jn.00048.2006","volume":"96","author":"JL Vincent","year":"2006","unstructured":"Vincent JL, Snyder AZ, Fox MD, Shannon BJ, Andrews JR, Raichle ME, Buckner RL: Coherent spontaneous activity identifies a hippocampal-parietal memory network. J Neurophysiol. 2006, 96: 3517-3531. 10.1152\/jn.00048.2006.","journal-title":"J Neurophysiol"},{"key":"1625_CR24","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1016\/j.mri.2007.10.011","volume":"26","author":"J Kim","year":"2008","unstructured":"Kim J, Horwitz B: Investigating the neural basis for fMRI-based functional connectivity in a blocked design: application to interregional correlations and psycho-physiological interactions. Magn Reson Imaging. 2008, 26: 583-593. 10.1016\/j.mri.2007.10.011.","journal-title":"Magn Reson Imaging"},{"key":"1625_CR25","doi-asserted-by":"publisher","first-page":"1258","DOI":"10.1126\/science.1546327","volume":"255","author":"DP Corina","year":"1992","unstructured":"Corina DP, Vaid J, Bellugi U: The linguistic basis of left hemisphere specialization. Science. 1992, 255: 1258-1260. 10.1126\/science.1546327.","journal-title":"Science"},{"key":"1625_CR26","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1038\/381699a0","volume":"381","author":"G Hickok","year":"1996","unstructured":"Hickok G, Bellugi U, Klima ES: The neurobiology of sign language and its implications for the neural basis of language. Nature. 1996, 381: 699-702. 10.1038\/381699a0.","journal-title":"Nature"},{"key":"1625_CR27","doi-asserted-by":"publisher","first-page":"13516","DOI":"10.1523\/JNEUROSCI.1680-09.2009","volume":"29","author":"G Josse","year":"2009","unstructured":"Josse G, Kherif F, Flandin G, Seghier ML, Price CJ: Predicting language lateralization from gray matter. J Neurosci. 2009, 29: 13516-13523. 10.1523\/JNEUROSCI.1680-09.2009.","journal-title":"J Neurosci"},{"key":"1625_CR28","doi-asserted-by":"publisher","first-page":"2033","DOI":"10.1016\/j.neuroimage.2009.10.055","volume":"49","author":"TM Ellmore","year":"2010","unstructured":"Ellmore TM, Beauchamp MS, Breier JI, Slater JD, Kalamangalam GP, O'Neill TJ, Disano MA, Tandon N: Temporal lobe white matter asymmetry and language laterality in epilepsy patients. Neuroimage. 2010, 49: 2033-2044. 10.1016\/j.neuroimage.2009.10.055.","journal-title":"Neuroimage"},{"key":"1625_CR29","doi-asserted-by":"publisher","first-page":"1705","DOI":"10.1007\/s00415-009-5187-2","volume":"256","author":"Z Zhang","year":"2009","unstructured":"Zhang Z, Lu G, Zhong Y, Tan Q, Liao W, Chen Z, Shi J, Liu Y: Impaired perceptual networks in temporal lobe epilepsy revealed by resting fMRI. J Neurol. 2009, 256: 1705-1713. 10.1007\/s00415-009-5187-2.","journal-title":"J Neurol"},{"key":"1625_CR30","doi-asserted-by":"publisher","first-page":"1580","DOI":"10.1002\/hbm.20625","volume":"30","author":"G Bettus","year":"2009","unstructured":"Bettus G, Guedj E, Joyeux F, Confort-Gouny S, Soulier E, Laguitton V, Cozzone PJ, Chauvel P, Ranjeva JP, Bartolomei F, Guye M: Decreased basal fMRI functional connectivity in epileptogenic networks and contralateral compensatory mechanisms. Hum Brain Mapp. 2009, 30: 1580-1591. 10.1002\/hbm.20625.","journal-title":"Hum Brain Mapp"},{"key":"1625_CR31","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1212\/WNL.0b013e3181b783dd","volume":"73","author":"AC Coan","year":"2009","unstructured":"Coan AC, Appenzeller S, Bonilha L, Li LM, Cendes F: Seizure frequency and lateralization affect progression of atrophy in temporal lobe epilepsy. Neurology. 2009, 73: 834-842. 10.1212\/WNL.0b013e3181b783dd.","journal-title":"Neurology"},{"key":"1625_CR32","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1136\/jnnp.2006.103994","volume":"78","author":"L Bonilha","year":"2007","unstructured":"Bonilha L, Rorden C, Halford JJ, Eckert M, Appenzeller S, Cendes F, Li LM: Asymmetrical extra-hippocampal grey matter loss related to hippocampal atrophy in patients with medial temporal lobe epilepsy. J Neurol Neurosurg Psychiatry. 2007, 78: 286-294. 10.1136\/jnnp.2006.103994.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"1625_CR33","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1212\/01.wnl.0000324264.96100.e0","volume":"71","author":"F Riederer","year":"2008","unstructured":"Riederer F, Lanzenberger R, Kaya M, Prayer D, Serles W, Baumgartner C: Network atrophy in temporal lobe epilepsy: a voxel-based morphometry study. Neurology. 2008, 71: 419-425. 10.1212\/01.wnl.0000324264.96100.e0.","journal-title":"Neurology"},{"key":"1625_CR34","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1001\/archneur.1997.00550160019010","volume":"54","author":"BP Hermann","year":"1997","unstructured":"Hermann BP, Seidenberg M, Schoenfeld J, Davies K: Neuropsychological characteristics of the syndrome of mesial temporal lobe epilepsy. Arch Neurol. 1997, 54: 369-376.","journal-title":"Arch Neurol"},{"key":"1625_CR35","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1016\/j.yebeh.2007.12.011","volume":"12","author":"NK Focke","year":"2008","unstructured":"Focke NK, Thompson PJ, Duncan JS: Correlation of cognitive functions with voxel-based morphometry in patients with hippocampal sclerosis. Epilepsy Behav. 2008, 12: 472-476. 10.1016\/j.yebeh.2007.12.011.","journal-title":"Epilepsy Behav"},{"key":"1625_CR36","doi-asserted-by":"publisher","first-page":"1512","DOI":"10.1111\/j.1528-1167.2007.01053.x","volume":"48","author":"HW Powell","year":"2007","unstructured":"Powell HW, Richardson MP, Symms MR, Boulby PA, Thompson PJ, Duncan JS, Koepp MJ: Reorganization of verbal and nonverbal memory in temporal lobe epilepsy due to unilateral hippocampal sclerosis. Epilepsia. 2007, 48: 1512-1525. 10.1111\/j.1528-1167.2007.01053.x.","journal-title":"Epilepsia"},{"key":"1625_CR37","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1684\/j.1950-6945.2002.tb00479.x","volume":"4","author":"FA Lado","year":"2002","unstructured":"Lado FA, Laureta EC, Moshe SL: Seizure-induced hippocampal damage in the mature and immature brain. Epileptic Disord. 2002, 4: 83-97.","journal-title":"Epileptic Disord"},{"key":"1625_CR38","doi-asserted-by":"publisher","first-page":"6174","DOI":"10.1523\/JNEUROSCI.1392-08.2008","volume":"28","author":"N Villain","year":"2008","unstructured":"Villain N, Desgranges B, Viader F, de la Sayette V, Mezenge F, Landeau B, Baron JC, Eustache F, Chetelat G: Relationships between hippocampal atrophy, white matter disruption, and gray matter hypometabolism in Alzheimer's disease. J Neurosci. 2008, 28: 6174-6181. 10.1523\/JNEUROSCI.1392-08.2008.","journal-title":"J Neurosci"},{"key":"1625_CR39","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1126\/science.1157086","volume":"321","author":"KB Kjelstrup","year":"2008","unstructured":"Kjelstrup KB, Solstad T, Brun VH, Hafting T, Leutgeb S, Witter MP, Moser EI, Moser MB: Finite scale of spatial representation in the hippocampus. Science. 2008, 321: 140-143. 10.1126\/science.1157086.","journal-title":"Science"},{"key":"1625_CR40","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1523\/JNEUROSCI.18-05-01841.1998","volume":"18","author":"G Fernandez","year":"1998","unstructured":"Fernandez G, Weyerts H, Schrader-Bolsche M, Tendolkar I, Smid HG, Tempelmann C, Hinrichs H, Scheich H, Elger CE, Mangun GR, Heinze HJ: Successful verbal encoding into episodic memory engages the posterior hippocampus: a parametrically analyzed functional magnetic resonance imaging study. J Neurosci. 1998, 18: 1841-1847.","journal-title":"J Neurosci"},{"key":"1625_CR41","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1038\/nn868","volume":"5","author":"S Knecht","year":"2002","unstructured":"Knecht S, Floel A, Drager B, Breitenstein C, Sommer J, Henningsen H, Ringelstein EB, Pascual-Leone A: Degree of language lateralization determines susceptibility to unilateral brain lesions. Nat Neurosci. 2002, 5: 695-699.","journal-title":"Nat Neurosci"},{"key":"1625_CR42","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1006\/nimg.2001.0978","volume":"15","author":"N Tzourio-Mazoyer","year":"2002","unstructured":"Tzourio-Mazoyer N, Landeau B, Papathanassiou D, Crivello F, Etard O, Delcroix N, Mazoyer B, Joliot M: Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage. 2002, 15: 273-289. 10.1006\/nimg.2001.0978.","journal-title":"Neuroimage"},{"key":"1625_CR43","first-page":"152","volume":"48","author":"T Butler","year":"2007","unstructured":"Butler T, Pan H, Pavony M, Xie XH, Ponticello L, Kandula P, Harden C, Labar D, Stern E, Silbersweig D: Resting state hippocampal functional connectivity in temporal lobe epilepsy. Epilepsia. 2007, 48: 152-153.","journal-title":"Epilepsia"},{"key":"1625_CR44","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1002\/ana.20733","volume":"59","author":"AB Waites","year":"2006","unstructured":"Waites AB, Briellmann RS, Saling MM, Abbott DF, Jackson GD: Functional connectivity networks are disrupted in left temporal lobe epilepsy. Ann Neurol. 2006, 59: 335-343. 10.1002\/ana.20733.","journal-title":"Ann Neurol"},{"key":"1625_CR45","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/0028-3932(71)90067-4","volume":"9","author":"RC Oldfield","year":"1971","unstructured":"Oldfield RC: The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia. 1971, 9: 97-113. 10.1016\/0028-3932(71)90067-4.","journal-title":"Neuropsychologia"},{"key":"1625_CR46","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1080\/01688638308401171","volume":"5","author":"D Fromm-Auch","year":"1983","unstructured":"Fromm-Auch D, Yeudall LT: Normative data for the Halstead-Reitan neuropsychological tests. J Clin Neuropsychol. 1983, 5: 221-238. 10.1080\/01688638308401171.","journal-title":"J Clin Neuropsychol"},{"key":"1625_CR47","volume-title":"Boston Naming Test","author":"EF Kaplan","year":"1983","unstructured":"Kaplan EF, Goodglass H, Weintaub S: Boston Naming Test. 1983, Philadelphia: Lea & Febiger"},{"key":"1625_CR48","first-page":"423","volume-title":"A compendium of neuropsychological tests: administration, norms and commentary","author":"O Spreen","year":"1998","unstructured":"Spreen O, Strauss E: Language tests. A compendium of neuropsychological tests: administration, norms and commentary. Edited by: Spreen O, Strauss E. 1998, New York: Oxford University Press, 423-480."},{"key":"1625_CR49","volume-title":"Mental status examination in neurology","author":"RL Strub","year":"1993","unstructured":"Strub RL, Black FW: Mental status examination in neurology. 1993, Philadelphia: F. A. Davis Company"},{"key":"1625_CR50","volume-title":"Wechsler Adult Intelligence Scale - revised","author":"D Wechsler","year":"1981","unstructured":"Wechsler D: Wechsler Adult Intelligence Scale - revised. 1981, New York: Pshychological Corp"},{"key":"1625_CR51","volume-title":"Wechsler Memory Scale - revised: manual","author":"D Wechsler","year":"1987","unstructured":"Wechsler D: Wechsler Memory Scale - revised: manual. 1987, San Diego: Pshychological Corp.\/Harcourt Brace Jovanovich"},{"key":"1625_CR52","unstructured":"Display - 3 D and Volume Program. [http:\/\/www.bic.mni.mcgill.ca\/ServicesSoftwareVisualization\/HomePage]"},{"key":"1625_CR53","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1002\/hbm.20023","volume":"22","author":"L Bonilha","year":"2004","unstructured":"Bonilha L, Kobayashi E, Cendes F, Min Li L: Protocol for volumetric segmentation of medial temporal structures using high-resolution 3-D magnetic resonance imaging. Hum Brain Mapp. 2004, 22: 145-154. 10.1002\/hbm.20023.","journal-title":"Hum Brain Mapp"},{"key":"1625_CR54","unstructured":"The Mathworks. [http:\/\/www.mathworks.com]"},{"key":"1625_CR55","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1002\/mrm.1910380114","volume":"38","author":"MH Buonocore","year":"1997","unstructured":"Buonocore MH, Gao L: Ghost artifact reduction for echo planar imaging using image phase correction. Magn Reson Med. 1997, 38: 89-100. 10.1002\/mrm.1910380114.","journal-title":"Magn Reson Med"},{"key":"1625_CR56","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1155\/2000\/421719","volume":"12","author":"C Rorden","year":"2000","unstructured":"Rorden C, Brett M: Stereotaxic display of brain lesions. Behav Neurol. 2000, 12: 191-200.","journal-title":"Behav Neurol"},{"key":"1625_CR57","unstructured":"MRIcro & MRIcron. [http:\/\/www.sph.sc.edu\/comd\/rorden\/]"},{"key":"1625_CR58","unstructured":"Statistical Parametric Mapping. [http:\/\/www.fil.ion.ucl.ac.uk\/spm\/]"},{"key":"1625_CR59","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1073\/pnas.0135058100","volume":"100","author":"MD Greicius","year":"2003","unstructured":"Greicius MD, Krasnow B, Reiss AL, Menon V: Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Proc Natl Acad Sci USA. 2003, 100: 253-258. 10.1073\/pnas.0135058100.","journal-title":"Proc Natl Acad Sci USA"},{"key":"1625_CR60","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1006\/cbmr.1996.0014","volume":"29","author":"RW Cox","year":"1996","unstructured":"Cox RW: AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. Comput Biomed Res. 1996, 29: 162-173. 10.1006\/cbmr.1996.0014.","journal-title":"Comput Biomed Res"},{"key":"1625_CR61","unstructured":"AFNI and NIfTI Server at the NIMH in Bethesda, MD USA. [http:\/\/afni.nimh.nih.gov\/afni]"},{"key":"1625_CR62","first-page":"162","volume-title":"Basics and clinical biostatistics","author":"B Dawson-Saunders","year":"1994","unstructured":"Dawson-Saunders B, Trapp RG: Association and Prediction. Basics and clinical biostatistics. Edited by: Dolan J, Langan C, Hornyak K. 1994, Norwalk, Connecticut: Appleton & Lange, 162-187."},{"key":"1625_CR63","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1006\/nimg.1997.0315","volume":"7","author":"MJ Lowe","year":"1998","unstructured":"Lowe MJ, Mock BJ, Sorenson JA: Functional connectivity in single and multislice echoplanar imaging using resting-state fluctuations. Neuroimage. 1998, 7: 119-132. 10.1006\/nimg.1997.0315.","journal-title":"Neuroimage"},{"key":"1625_CR64","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1016\/j.neuroimage.2005.12.033","volume":"31","author":"L Wang","year":"2006","unstructured":"Wang L, Zang Y, He Y, Liang M, Zhang X, Tian L, Wu T, Jiang T, Li K: Changes in hippocampal connectivity in the early stages of Alzheimer's disease: evidence from resting state fMRI. Neuroimage. 2006, 31: 496-504. 10.1016\/j.neuroimage.2005.12.033.","journal-title":"Neuroimage"}],"container-title":["BMC Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2202-11-66.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T15:39:28Z","timestamp":1740152368000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcneurosci.biomedcentral.com\/articles\/10.1186\/1471-2202-11-66"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6,2]]},"references-count":64,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["1625"],"URL":"https:\/\/doi.org\/10.1186\/1471-2202-11-66","relation":{},"ISSN":["1471-2202"],"issn-type":[{"value":"1471-2202","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,6,2]]},"assertion":[{"value":"4 September 2009","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 June 2010","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 June 2010","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"66"}}