{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T23:47:51Z","timestamp":1791330471739,"version":"4.3.1"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2007,8,29]],"date-time":"2007-08-29T00:00:00Z","timestamp":1188345600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Neurosci"],"published-print":{"date-parts":[[2007,12]]},"DOI":"10.1186\/1471-2202-8-69","type":"journal-article","created":{"date-parts":[[2007,8,29]],"date-time":"2007-08-29T18:13:28Z","timestamp":1188411208000},"source":"Crossref","is-referenced-by-count":37,"title":["Glutamatergic alterations in the cortex of genetic absence epilepsy rats"],"prefix":"10.1186","volume":"8","author":[{"given":"Monique","family":"Touret","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandrine","family":"Parrot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc","family":"Denoroy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Fran\u00e7oise","family":"Belin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne","family":"Didier-Bazes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2007,8,29]]},"reference":[{"key":"367_CR1","first-page":"37","volume":"35","author":"C Marescaux","year":"1992","unstructured":"Marescaux C, Vergnes M, Depaulis A: Genetic absence epilepsy in rats from Strasbourg \u2013 a review. J Neural Transm Suppl. 1992, 35: 37-69.","journal-title":"J Neural Transm Suppl"},{"issue":"1","key":"367_CR2","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/S0301-0082(97)00091-9","volume":"55","author":"L Danober","year":"1998","unstructured":"Danober L, Deransart C, Depaulis A, Vergnes M, Marescaux C: Pathophysiological mechanisms of genetic absence epilepsy in the rat. Prog Neurobiol. 1998, 55 (1): 27-57. 10.1016\/S0301-0082(97)00091-9.","journal-title":"Prog Neurobiol"},{"issue":"4","key":"367_CR3","doi-asserted-by":"publisher","first-page":"1674","DOI":"10.1046\/j.1471-4159.1995.65041674.x","volume":"65","author":"DA Richards","year":"1995","unstructured":"Richards DA, Lemos T, Whitton PS, Bowery NG: Extracellular GABA in the ventrolateral thalamus of rats exhibiting spontaneous absence epilepsy: a microdialysis study. J Neurochem. 1995, 65 (4): 1674-1680.","journal-title":"J Neurochem"},{"issue":"5","key":"367_CR4","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1016\/S0197-0186(99)00046-7","volume":"34","author":"RJ Sutch","year":"1999","unstructured":"Sutch RJ, Davies CC, Bowery NG: GABA release and uptake measured in crude synaptosomes from Genetic Absence Epilepsy Rats from Strasbourg (GAERS). Neurochem Int. 1999, 34 (5): 415-425. 10.1016\/S0197-0186(99)00046-7.","journal-title":"Neurochem Int"},{"issue":"1","key":"367_CR5","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1002\/1098-1136(200010)32:1<15::AID-GLIA20>3.0.CO;2-#","volume":"32","author":"M Dutuit","year":"2000","unstructured":"Dutuit M, Didier-Bazes M, Vergnes M, Mutin M, Conjard A, Akaoka H, Belin MF, Touret M: Specific alteration in the expression of glial fibrillary acidic protein, glutamate dehydrogenase, and glutamine synthetase in rats with genetic absence epilepsy. Glia. 2000, 32 (1): 15-24. 10.1002\/1098-1136(200010)32:1<15::AID-GLIA20>3.0.CO;2-#.","journal-title":"Glia"},{"issue":"6","key":"367_CR6","doi-asserted-by":"publisher","first-page":"1029","DOI":"10.1046\/j.0022-3042.2002.00768.x","volume":"80","author":"M Dutuit","year":"2002","unstructured":"Dutuit M, Touret M, Szymocha R, Nehlig A, Belin MF, Didier-Bazes M: Decreased expression of glutamate transporters in genetic absence epilepsy rats before seizure occurrence. J Neurochem. 2002, 80 (6): 1029-1038. 10.1046\/j.0022-3042.2002.00768.x.","journal-title":"J Neurochem"},{"key":"367_CR7","first-page":"97","volume":"35","author":"R Pumain","year":"1992","unstructured":"Pumain R, Louvel J, Gastard M, Kurcewicz I, Vergnes M: Responses to N-methyl-D-aspartate are enhanced in rats with petit mal-like seizures. J Neural Transm Suppl. 1992, 35: 97-108.","journal-title":"J Neural Transm Suppl"},{"issue":"1","key":"367_CR8","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/0920-1211(96)00015-0","volume":"25","author":"C Koerner","year":"1996","unstructured":"Koerner C, Danober L, Boehrer A, Marescaux C, Vergnes M: Thalamic NMDA transmission in a genetic model of absence epilepsy in rats. Epilepsy Res. 1996, 25 (1): 11-19. 10.1016\/0920-1211(96)00015-0.","journal-title":"Epilepsy Res"},{"issue":"3","key":"367_CR9","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/S0168-0102(01)00232-2","volume":"40","author":"F Dufour","year":"2001","unstructured":"Dufour F, Nalecz KA, Nalecz MJ, Nehlig A: Modulation of absence seizures by branched-chain amino acids: correlation with brain amino acid concentrations. Neurosci Res. 2001, 40 (3): 255-263. 10.1016\/S0168-0102(01)00232-2.","journal-title":"Neurosci Res"},{"issue":"5481","key":"367_CR10","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1126\/science.289.5481.957","volume":"289","author":"EE Bellocchio","year":"2000","unstructured":"Bellocchio EE, Reimer RJ, Fremeau RT, Edwards RH: Uptake of glutamate into synaptic vesicles by an inorganic phosphate transporter. Science. 2000, 289 (5481): 957-960. 10.1126\/science.289.5481.957.","journal-title":"Science"},{"issue":"3","key":"367_CR11","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1016\/S0896-6273(00)81122-8","volume":"24","author":"R Janz","year":"1999","unstructured":"Janz R, Sudhof TC, Hammer RE, Unni V, Siegelbaum SA, Bolshakov VY: Essential roles in synaptic plasticity for synaptogyrin I and synaptophysin I. Neuron. 1999, 24 (3): 687-700. 10.1016\/S0896-6273(00)81122-8.","journal-title":"Neuron"},{"issue":"10","key":"367_CR12","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1078\/0171-9335-00196","volume":"80","author":"B Hinz","year":"2001","unstructured":"Hinz B, Becher A, Mitter D, Schulze K, Heinemann U, Draguhn A, Ahnert-Hilger G: Activity-dependent changes of the presynaptic synaptophysin-synaptobrevin complex in adult rat brain. Eur J Cell Biol. 2001, 80 (10): 615-619. 10.1078\/0171-9335-00196.","journal-title":"Eur J Cell Biol"},{"issue":"3","key":"367_CR13","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1113\/jphysiol.2003.046573","volume":"552","author":"D Pinault","year":"2003","unstructured":"Pinault D: Cellular interactions in the rat somatosensory thalamocortical system during normal and epileptic 5\u20139 Hz. J Physiol. 2003, 552 (3): 881-905. 10.1113\/jphysiol.2003.046573.","journal-title":"J Physiol"},{"issue":"3","key":"367_CR14","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1001\/archneur.62.3.371","volume":"62","author":"H Meeren","year":"2005","unstructured":"Meeren H, van Luijtelaar G, Lopes da Silva F, Coenen A: Evolving concepts on the pathophysiology of absence seizures: the cortical focus theory. Arch Neurol. 2005, 62 (3): 371-376. 10.1001\/archneur.62.3.371.","journal-title":"Arch Neurol"},{"issue":"1","key":"367_CR15","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/j.neuroscience.2003.09.026","volume":"123","author":"JP Manning","year":"2004","unstructured":"Manning JP, Richards DA, Leresche N, Crunelli V, Bowery NG: Cortical-area specific block of genetically determined absence seizures by ethosuximide. Neuroscience. 2004, 123 (1): 5-9. 10.1016\/j.neuroscience.2003.09.026.","journal-title":"Neuroscience"},{"issue":"1","key":"367_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/1098-1136(200010)32:1<1::AID-GLIA10>3.0.CO;2-W","volume":"32","author":"CM Anderson","year":"2000","unstructured":"Anderson CM, Swanson RA: Astrocyte glutamate transport: review of properties, regulation, and physiological functions. Glia. 2000, 32 (1): 1-14. 10.1002\/1098-1136(200010)32:1<1::AID-GLIA10>3.0.CO;2-W.","journal-title":"Glia"},{"issue":"1","key":"367_CR17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0301-0082(00)00067-8","volume":"65","author":"NC Danbolt","year":"2001","unstructured":"Danbolt NC: Glutamate uptake. Prog Neurobiol. 2001, 65 (1): 1-105. 10.1016\/S0301-0082(00)00067-8.","journal-title":"Prog Neurobiol"},{"issue":"1\u20132","key":"367_CR18","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/S0169-328X(00)00194-7","volume":"83","author":"S Hisano","year":"2000","unstructured":"Hisano S, Hoshi K, Ikeda Y, Maruyama D, Kanemoto M, Ichijo H, Kojima I, Takeda J, Nogami H: Regional expression of a gene encoding a neuron-specific Na(+)-dependent inorganic phosphate cotransporter (DNPI) in the rat forebrain. Brain Res Mol Brain Res. 2000, 83 (1\u20132): 34-43. 10.1016\/S0169-328X(00)00194-7.","journal-title":"Brain Res Mol Brain Res"},{"issue":"1","key":"367_CR19","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1002\/cne.10129","volume":"444","author":"T Kaneko","year":"2002","unstructured":"Kaneko T, Fujiyama F, Hioki H: Immunohistochemical localization of candidates for vesicular glutamate transporters in the rat brain. J Comp Neurol. 2002, 444 (1): 39-62. 10.1002\/cne.10129.","journal-title":"J Comp Neurol"},{"issue":"1","key":"367_CR20","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1523\/JNEUROSCI.22-01-00142.2002","volume":"22","author":"H Varoqui","year":"2002","unstructured":"Varoqui H, Schafer MK, Zhu H, Weihe E, Erickson JD: Identification of the differentiation-associated Na+\/PI transporter as a novel vesicular glutamate transporter expressed in a distinct set of glutamatergic synapses. J Neurosci. 2002, 22 (1): 142-155.","journal-title":"J Neurosci"},{"issue":"8","key":"367_CR21","doi-asserted-by":"crossref","first-page":"5789","DOI":"10.1523\/JNEUROSCI.15-08-05789.1995","volume":"15","author":"B Ni","year":"1995","unstructured":"Ni B, Wu X, Yan GM, Wang J, Paul SM: Regional expression and cellular localization of the Na(+)-dependent inorganic phosphate cotransporter of rat brain. J Neurosci. 1995, 15 (8): 5789-5799.","journal-title":"J Neurosci"},{"issue":"2","key":"367_CR22","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/S0165-3806(02)00617-X","volume":"140","author":"A Minelli","year":"2003","unstructured":"Minelli A, Edwards RH, Manzoni T, Conti F: Postnatal development of the glutamate vesicular transporter VGLUT1 in rat cerebral cortex. Brain Res Dev Brain Res. 2003, 140 (2): 309-314. 10.1016\/S0165-3806(02)00617-X.","journal-title":"Brain Res Dev Brain Res"},{"issue":"3","key":"367_CR23","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1002\/cne.20354","volume":"480","author":"JL Boulland","year":"2004","unstructured":"Boulland JL, Qureshi T, Seal RP, Rafiki A, Gundersen V, Bergersen LH, Fremeau RT, Edwards RH, Storm-Mathisen J, Chaudhry FA: Expression of the vesicular glutamate transporters during development indicates the widespread corelease of multiple neurotransmitters. J Comp Neurol. 2004, 480 (3): 264-280. 10.1002\/cne.20354.","journal-title":"J Comp Neurol"},{"issue":"6","key":"367_CR24","doi-asserted-by":"publisher","first-page":"1223","DOI":"10.1016\/0896-6273(95)90002-0","volume":"15","author":"AS LaMantia","year":"1995","unstructured":"LaMantia AS: The usual suspects: GABA and glutamate may regulate proliferation in the neocortex. Neuron. 1995, 15 (6): 1223-1225. 10.1016\/0896-6273(95)90002-0.","journal-title":"Neuron"},{"issue":"5","key":"367_CR25","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1002\/glia.440030503","volume":"3","author":"AH Cornell-Bell","year":"1990","unstructured":"Cornell-Bell AH, Thomas PG, Smith SJ: The excitatory neurotransmitter glutamate causes filopodia formation in cultured hippocampal astrocytes. Glia. 1990, 3 (5): 322-334. 10.1002\/glia.440030503.","journal-title":"Glia"},{"issue":"5","key":"367_CR26","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1002\/jnr.10797","volume":"74","author":"H Monnerie","year":"2003","unstructured":"Monnerie H, Shashidhara S, Le Roux PD: Effect of excess extracellular glutamate on dendrite growth from cerebral cortical neurons at 3 days in vitro: Involvement of NMDA receptors. J Neurosci Res. 2003, 74 (5): 688-700. 10.1002\/jnr.10797.","journal-title":"J Neurosci Res"},{"key":"367_CR27","first-page":"119","volume-title":"Neurosci Res","author":"AV Karpova","year":"2005","unstructured":"Karpova AV, Bikbaev AF, Coenen AML, van Luijtelaar G: Morphometric Golgi study of cortical location in WAG\/Rij rats: the cortical focus theory. Neurosci Res. 2005, 119-128. 10.1016\/j.neures.2004.10.004."},{"key":"367_CR28","volume-title":"The rat brain in stereotaxic coordinates, New York","author":"G Paxinos","year":"1998","unstructured":"Paxinos G, Watson C: The rat brain in stereotaxic coordinates, New York. 1998, 4","edition":"4"},{"issue":"1\u20132","key":"367_CR29","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.jneumeth.2004.04.042","volume":"140","author":"L Bert","year":"2004","unstructured":"Bert L, Favale D, Jego G, Greve P, Guilloux JP, Guiard BP, Gardier AM, Suaud-Chagny MF, Lestage P: Rapid and precise method to locate microdialysis probe implantation in the rodent brain. J Neurosci Methods. 2004, 140 (1\u20132): 53-57. 10.1016\/j.jneumeth.2004.04.042.","journal-title":"J Neurosci Methods"},{"issue":"3","key":"367_CR30","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/0165-0270(93)90097-B","volume":"48","author":"JB Justice","year":"1993","unstructured":"Justice JB: Quantitative microdialysis of neurotransmitters. J Neurosci Methods. 1993, 48 (3): 263-276. 10.1016\/0165-0270(93)90097-B.","journal-title":"J Neurosci Methods"},{"issue":"3","key":"367_CR31","first-page":"189","volume":"8","author":"LH Parsons","year":"1994","unstructured":"Parsons LH, Justice JB: Quantitative approaches to in vivo brain microdialysis. Crit Rev Neurobiol. 1994, 8 (3): 189-220.","journal-title":"Crit Rev Neurobiol"},{"issue":"18","key":"367_CR32","doi-asserted-by":"publisher","first-page":"3187","DOI":"10.1002\/elps.200305565","volume":"24","author":"V Sauvinet","year":"2003","unstructured":"Sauvinet V, Parrot S, Benturquia N, Bravo-Moraton E, Renaud B, Denoroy L: In vivo simultaneous monitoring of gamma-aminobutyric acid, glutamate, and L-aspartate using brain microdialysis and capillary electrophoresis with laser-induced fluorescence detection: Analytical developments and in vitro\/in vivo validations. Electrophoresis. 2003, 24 (18): 3187-3196. 10.1002\/elps.200305565.","journal-title":"Electrophoresis"},{"issue":"1\u20132","key":"367_CR33","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0006-8993(97)00519-2","volume":"766","author":"GM Alexander","year":"1997","unstructured":"Alexander GM, Grothusen JR, Gordon SW, Schwartzman RJ: Intracerebral microdialysis study of glutamate reuptake in awake, behaving rats. Brain Res. 1997, 766 (1\u20132): 1-10. 10.1016\/S0006-8993(97)00519-2.","journal-title":"Brain Res"}],"container-title":["BMC Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2202-8-69.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2202-8-69\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2202-8-69.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,21]],"date-time":"2019-01-21T19:02:25Z","timestamp":1548097345000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcneurosci.biomedcentral.com\/articles\/10.1186\/1471-2202-8-69"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8,29]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,12]]}},"alternative-id":["367"],"URL":"https:\/\/doi.org\/10.1186\/1471-2202-8-69","relation":{},"ISSN":["1471-2202"],"issn-type":[{"value":"1471-2202","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,8,29]]},"article-number":"69"}}