{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T12:52:17Z","timestamp":1789131137755,"version":"build-2803163510"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2010,1,12]],"date-time":"2010-01-12T00:00:00Z","timestamp":1263254400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Gastroenterol"],"published-print":{"date-parts":[[2010,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Ectopic biliary drainage is a rare congenital anomaly on which we have scarce data in the current literature.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>The data were collected from the records of 400 endoscopic retrograde cholangio-pancreatography (ERCP). In this report, we present 10 cases (male\/female: 9\/1, mean age 54 years, range 38-74) with ectopic biliary openings into the duodenum and\/or stomach diagnosed by endoscopic retrograde cholangio-pancreatography (ERCP).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>In our series, the frequency of ectopic biliary drainage is 2% (10 out of 400 ERCPs). Recurrent attacks of cholangitis and complicated ulcer formation in the distal stomach and bulbar duodenum were the most common signs in the present series. The sites of ectopic biliary drainage were the stomach in 1 case, the duodenum bulbus in 7 cases and the postbulbar duodenum in 2 cases. Bulbar ulcer, deformed pylorus and bulbus were present in 7 cases, apical bulbar stricture in 2, gastric ulcer in 1, pyloroplasty and\/or gastroenterostomy in 3 cases. One case had had previous bleeding episode. Some of them had undergone previous surgeries for gall-stone disease (cholecystectomy in 5 cases, bile duct operation in 3 cases) and ulcer complications (pyloroplasty\/gastroenterostomy in 3 cases). ERCP revealed dilatation of the biliary tree and hook shaped distal choledochus in all cases, choledocholithiasis in 7 and Mirizzi syndrome in 1. Endoscopic balloon dilatations for gastric outlet obstruction, extraction of bile stones after balloon dilating the ectopic site, surgery for difficult cases with large bile duct stones or with gastric outlet obstruction were preferred methods in this series of patients.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>With this report, we have to remind that ectopic biliary drainage must be considered in the differential diagnosis when the clinician faces cases with gastric outlet obstruction due to peptic ulcer formation accompanied by cholangitis\/cholestasis.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1471-230x-10-2","type":"journal-article","created":{"date-parts":[[2010,1,12]],"date-time":"2010-01-12T19:14:51Z","timestamp":1263323691000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["The clinical presentations of ectopic biliary drainage into duodenal bulbus and stomach with a thorough review of the current literature"],"prefix":"10.1186","volume":"10","author":[{"given":"Ulku","family":"Saritas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Altug","family":"Senol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yucel","family":"Ustundag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,1,12]]},"reference":[{"key":"393_CR1","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1055\/s-2003-39675","volume":"35","author":"E Ozaslan","year":"2003","unstructured":"Ozaslan E, Saritas U, Tatar G, Simsek H: Ectopic drainage of the common bile duct into the duodenal bulb: report of two cases. Endoscopy. 2003, 35: 545-10.1055\/s-2003-39675.","journal-title":"Endoscopy"},{"key":"393_CR2","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1097\/00000658-197407000-00018","volume":"180","author":"EV Quintana","year":"1974","unstructured":"Quintana EV, Labat R: Ectopic drainage of the common bile duct. Ann Surg. 1974, 180: 119-23. 10.1097\/00000658-197407000-00018.","journal-title":"Ann Surg"},{"key":"393_CR3","first-page":"238","volume":"17","author":"K Hekimoglu","year":"2008","unstructured":"Hekimoglu K, Ustundag Y, Saritas U: Ectopic openings of the bilio-pancreatic ducts in the stomach in an elderly case presenting with choledocholithiasis and acute cholangitis. J Gastrointestin Liver Dis. 2008, 17: 238-9.","journal-title":"J Gastrointestin Liver Dis"},{"key":"393_CR4","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1001\/archsurg.1985.01390330083018","volume":"120","author":"J Doty","year":"1985","unstructured":"Doty J, Hassal E, Fonkalsrud EW: Anomalous drainage of the common bile duct into the fourth portion of the duodenum. Arch Surg. 1985, 120: 1077-9.","journal-title":"Arch Surg"},{"key":"393_CR5","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1055\/s-2007-1001224","volume":"30","author":"Y Ko\u015far","year":"1998","unstructured":"Ko\u015far Y, G\u00fcrkaynak G, Tezel A, O\u011fuz D, Sahin B: Biliary opening anomalies: ectopic drainage of pancreaticobiliary ducts. Endoscopy. 1998, 30: S4-5.","journal-title":"Endoscopy"},{"key":"393_CR6","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1016\/j.gie.2006.06.023","volume":"65","author":"MH Song","year":"2007","unstructured":"Song MH, Jun DW, Kim SH, Lee HH, Jo YJ, Park YS: Recurrent duodenal ulcer and cholangitis associated with ectopic opening of bile duct in the duodenal bulb. Gastrointest Endosc. 2007, 65: 324-5. 10.1016\/j.gie.2006.06.023.","journal-title":"Gastrointest Endosc"},{"key":"393_CR7","doi-asserted-by":"publisher","first-page":"1853","DOI":"10.2169\/internalmedicine.46.0190","volume":"46","author":"HY Sung","year":"2007","unstructured":"Sung HY, Kim JI, Park YB, Cheung DY, Cho SH, Park SH, Han JY, Kim JK: The papilla of Vater just below the pylorus presenting as recurrent duodenal ulcer bleeding. Intern Med. 2007, 46: 1853-6. 10.2169\/internalmedicine.46.0190.","journal-title":"Intern Med"},{"key":"393_CR8","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1067\/mge.2003.210","volume":"57","author":"SS Lee","year":"2003","unstructured":"Lee SS, Kim MH, Lee SK, Kim KP, Kim HJ, Bae JS, Kim HJ, Seo DW, Ha HK, Kim JS, Kim CD, Chung JP, Min YI: Ectopic opening of the common bile duct in the duodenal bulb: clinical implications. Gastrointest Endosc. 2003, 57: 679-82. 10.1067\/mge.2003.210.","journal-title":"Gastrointest Endosc"},{"key":"393_CR9","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1007\/s00276-001-0269-6","volume":"23","author":"P Bernard","year":"2001","unstructured":"Bernard P, Le Borgne J, Dupas B, Kohnen-Shari N, Raoult S, Hamel A: Double common bile duct with ectopic drainage into the stomach. Case report and review of the literature. Surg Radiol Anat. 2001, 23: 269-72. 10.1007\/s00276-001-0269-6.","journal-title":"Surg Radiol Anat"},{"key":"393_CR10","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1097\/SLE.0b013e3181257256","volume":"17","author":"P Katsinelos","year":"2007","unstructured":"Katsinelos P, Papaziogas B, Paraskevas G, Chatzimavroudis G, Koutelidakis J, Katsinelos T, Paroutoglou G: Ectopic papilla of vater in the stomach, blind antrum with aberrant pyloric opening, and congenital gastric diverticula: an unreported association. Surg Laparosc Endosc Percutan Tech. 2007, 17: 434-7. 10.1097\/SLE.0b013e3181257256.","journal-title":"Surg Laparosc Endosc Percutan Tech"},{"key":"393_CR11","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1007\/BF01888503","volume":"17","author":"M Kanematsu","year":"1992","unstructured":"Kanematsu M, Imaeda T, Seki M, Goto H, Doi H, Shimokawa K: Accessory bile duct draining into the stomach: case report and review. Gastrointest Radiol. 1992, 17: 27-30. 10.1007\/BF01888503.","journal-title":"Gastrointest Radiol"},{"key":"393_CR12","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1002\/1097-0142(19860101)57:1<138::AID-CNCR2820570128>3.0.CO;2-M","volume":"57","author":"K Kondo","year":"1986","unstructured":"Kondo K, Yokoyama I, Yokoyama Y, Harada A, Nagayo T: Two cases of gastric cancer-bearing double choledochus with ectopic drainage into the stomach. Cancer. 1986, 57: 138-41. 10.1002\/1097-0142(19860101)57:1<138::AID-CNCR2820570128>3.0.CO;2-M.","journal-title":"Cancer"},{"key":"393_CR13","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/1471-230X-7-26","volume":"7","author":"S Disibeyaz","year":"2007","unstructured":"Disibeyaz S, Parlak E, Cicek B, Cengiz C, Kuran SO, Oguz D, G\u00fczel H, Sahin B: Anomalous opening of the common bile duct into the duodenal bulb: endoscopic treatment. BMC Gastroenterol. 2007, 7: 26-10.1186\/1471-230X-7-26.","journal-title":"BMC Gastroenterol"},{"key":"393_CR14","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1097\/00000658-197611000-00017","volume":"184","author":"HH Lindner","year":"1976","unstructured":"Lindner HH, Pena VA, Ruggeri RA: A clinical and anatomical study of anomalous termination of the common bile duct into the duodenum. Ann Surg. 1976, 184: 626-32. 10.1097\/00000658-197611000-00017.","journal-title":"Ann Surg"},{"key":"393_CR15","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1067\/msy.2002.124025","volume":"131","author":"K Yamashita","year":"2002","unstructured":"Yamashita K, Oka Y, Urakami A, Iwamoto S, Tsunoda T, Eto T: Double common bile duct: a case report and a review of the Japanese literature. Surgery. 2002, 131: 676-81. 10.1067\/msy.2002.124025.","journal-title":"Surgery"},{"key":"393_CR16","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1007\/s00383-002-0914-0","volume":"19","author":"L Li","year":"2003","unstructured":"Li L, Yamataka A, Wang YX, Wang DY, Wang K, Li ZX, Shimizu T, Yamashiro Y, Zhang JZ, Lane GJ, Miyano T: Anomalous pancreatic duct anatomy, ectopic distal location of the papilla of Vater and congenital biliary dilatation: a new developmental triad?. Pediatr Surg Int. 2003, 19: 180-5.","journal-title":"Pediatr Surg Int"},{"key":"393_CR17","first-page":"51","volume":"64","author":"G Paraskevas","year":"2005","unstructured":"Paraskevas G, Papaziogas B, Natsis K, Katsinelos P, Gigis P, Atmatzidis K: Abnormal location of papilla of Vater: a cadaveric study. Folia Morphol (Warsz). 2005, 64: 51-3.","journal-title":"Folia Morphol (Warsz)"},{"key":"393_CR18","doi-asserted-by":"publisher","first-page":"79","DOI":"10.2169\/internalmedicine1962.27.79","volume":"27","author":"T Kubota","year":"1988","unstructured":"Kubota T, Fujioka T, Honda S, Suetsuna J, Matsunaga K, Terao H, Nasu M: The papilla of Vater emptying into the duodenal bulb. Report of two cases. Jpn J Med. 1988, 27: 79-82.","journal-title":"Jpn J Med"},{"key":"393_CR19","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1097\/00004728-200201000-00024","volume":"26","author":"Y Amano","year":"2002","unstructured":"Amano Y, Takahashi M, Oishi T, Kumazaki T: MR cholangiopancreatography of double common bile duct with ectopic drainage into stomach. J Comput Assist Tomogr. 2002, 26: 141-2. 10.1097\/00004728-200201000-00024.","journal-title":"J Comput Assist Tomogr"},{"key":"393_CR20","doi-asserted-by":"publisher","first-page":"5068","DOI":"10.3748\/wjg.v11.i32.5068","volume":"11","author":"M Krstic","year":"2005","unstructured":"Krstic M, Stimec B, Krstic R, Ugljesic M, Knezevic S, Jovanovic I: EUS diagnosis of ectopic opening of the common bile duct in the duodenal bulb: a case report. World J Gastroenterol. 2005, 11: 5068-71.","journal-title":"World J Gastroenterol"},{"key":"393_CR21","doi-asserted-by":"publisher","first-page":"517","DOI":"10.2214\/ajr.169.2.9242767","volume":"169","author":"HJ Lee","year":"1997","unstructured":"Lee HJ, Ha HK, Kim MH, Jeong YK, Kim PN, Lee MG, Kim JS, Suh DJ, Lee SG, Min YI, Auh YH: ERCP and CT findings of ectopic drainage of the common bile duct into the duodenal bulb. Am J Roentgenol. 1997, 169: 517-20.","journal-title":"Am J Roentgenol"}],"container-title":["BMC Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-230X-10-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-230X-10-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-230X-10-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-230X-10-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T06:13:22Z","timestamp":1630476802000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/10.1186\/1471-230X-10-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1,12]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["393"],"URL":"https:\/\/doi.org\/10.1186\/1471-230x-10-2","relation":{},"ISSN":["1471-230X"],"issn-type":[{"value":"1471-230X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1,12]]},"assertion":[{"value":"19 January 2009","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 January 2010","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 January 2010","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"2"}}