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The purpose of this study has been to explore the accuracy of TE and clinical parameters in predicting the presence of esophageal\/gastric varices in children with biliary atresia (BA) following portoenterostomy.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>Patients with BA status post portoenterostomy and normal children were recruited. Splenomegaly and presence of EV\/GV were determined by physical examination and endoscopy, respectively. Aspartate transaminase to platelet ratio index (APRI) was used as a serum fibrosis marker. TE was performed by using FibroScan. Data was expressed as mean \u00b1 SD.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Seventy-three BA patients (male:female = 32:41; age 9.11 \u00b1 5.64 years) and 50 normal controls (male:female = 19:31; age 11.00 \u00b1 3.31 years) were enrolled. The liver stiffness score of BA patients was significantly higher than that of normal controls (27.37 \u00b1 22.48 and 4.69 \u00b1 1.03 kPa; <jats:italic>p<\/jats:italic> &lt; 0.001). Patients with EV\/GV had significantly higher liver stiffness score and APRI than those without EV\/GV. As for EV\/GV diagnosis, the areas under the receiver operating characteristic curve were 0.89 (95% CI 0.80 to 0.98) for TE and 0.87 (95% CI 0.78 to 0.96) for APRI, respectively. The sensitivity (and specificity) of TE (using a cut-off value of 12.7 kPa) and APRI (using a cut-off value of 1.92) in predicting EV\/GV were 84% (77%) and 84% (83%), respectively, whereas the sensitivity (and specificity) of splenomegaly in predicting EV\/GV were 92% (85%).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Transient elastography is a useful tool for predicting the presence of EV\/GV. In addition, basic physical examination, routine biochemical and hematological tests, are still worthwhile and correlate well with the presence of EV\/GV in patients with BA post portoenterostomy.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1471-230x-11-41","type":"journal-article","created":{"date-parts":[[2011,5,6]],"date-time":"2011-05-06T18:31:20Z","timestamp":1304706680000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":70,"title":["Transient elastography for predicting esophageal\/gastric varices in children with biliary atresia"],"prefix":"10.1186","volume":"11","author":[{"given":"Voranush","family":"Chongsrisawat","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paisarn","family":"Vejapipat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nipaporn","family":"Siripon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Poovorawan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,4,18]]},"reference":[{"issue":"3","key":"570_CR1","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1016\/S0889-8553(03)00049-9","volume":"32","author":"BA Haber","year":"2003","unstructured":"Haber BA, Russo P: Biliary atresia. 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