{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T20:56:16Z","timestamp":1770324976146,"version":"3.49.0"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2008,1,21]],"date-time":"2008-01-21T00:00:00Z","timestamp":1200873600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Geriatr"],"published-print":{"date-parts":[[2008,12]]},"DOI":"10.1186\/1471-2318-8-2","type":"journal-article","created":{"date-parts":[[2008,1,22]],"date-time":"2008-01-22T07:15:02Z","timestamp":1200986102000},"source":"Crossref","is-referenced-by-count":28,"title":["(Cost)-effectiveness of family meetings on indicated prevention of anxiety and depressive symptoms and disorders of primary family caregivers of patients with dementia: design of a randomized controlled trial"],"prefix":"10.1186","volume":"8","author":[{"given":"Karlijn J","family":"Joling","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hein PJ","family":"van Hout","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Scheltens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myrra","family":"Vernooij-Dassen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard","family":"van den Berg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith","family":"Bosmans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Freek","family":"Gillissen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Mittelman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harm WJ","family":"van Marwijk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,1,21]]},"reference":[{"key":"96_CR1","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1093\/ije\/20.3.736","volume":"20","author":"A Hofman","year":"1991","unstructured":"Hofman A, Rocca WA, Brayne C, Breteler MM, Clarke M, Cooper B, Copeland JR, Dartigues JF, da Silva DA, Hagnell O, .: The prevalence of dementia in Europe: a collaborative study of 1980-1990 findings. Eurodem Prevalence Research Group. Int J Epidemiol. 1991, 20: 736-748. 10.1093\/ije\/20.3.736.","journal-title":"Int J Epidemiol"},{"key":"96_CR2","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1016\/j.eurpsy.2003.03.003","volume":"18","author":"J Wancata","year":"2003","unstructured":"Wancata J, Musalek M, Alexandrowicz R, Krautgartner M: Number of dementia sufferers in Europe between the years 2000 and 2050. Eur Psychiatry. 2003, 18: 306-313. 10.1016\/j.eurpsy.2003.03.003.","journal-title":"Eur Psychiatry"},{"key":"96_CR3","doi-asserted-by":"publisher","first-page":"2215","DOI":"10.1001\/jama.282.23.2215","volume":"282","author":"R Schulz","year":"1999","unstructured":"Schulz R, Beach SR: Caregiving as a risk factor for mortality: the Caregiver Health Effects Study. JAMA. 1999, 282: 2215-2219. 10.1001\/jama.282.23.2215.","journal-title":"JAMA"},{"key":"96_CR4","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1037\/0882-7974.6.3.392","volume":"6","author":"PP Vitaliano","year":"1991","unstructured":"Vitaliano PP, Russo J, Young HM, Teri L, Maiuro RD: Predictors of burden in spouse caregivers of individuals with Alzheimer's disease. Psychol Aging. 1991, 6: 392-402. 10.1037\/0882-7974.6.3.392.","journal-title":"Psychol Aging"},{"key":"96_CR5","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1097\/00006842-199107000-00001","volume":"53","author":"JK Kiecolt-Glaser","year":"1991","unstructured":"Kiecolt-Glaser JK, Dura JR, Speicher CE, Trask OJ, Glaser R: Spousal caregivers of dementia victims: longitudinal changes in immunity and health. Psychosom Med. 1991, 53: 345-362.","journal-title":"Psychosom Med"},{"key":"96_CR6","doi-asserted-by":"publisher","first-page":"351","DOI":"10.3109\/00048679009077702","volume":"24","author":"H Brodaty","year":"1990","unstructured":"Brodaty H, Hadzi-Pavlovic D: Psychosocial effects on carers of living with persons with dementia. Aust N Z J Psychiatry. 1990, 24: 351-361. 10.3109\/00048679009077702.","journal-title":"Aust N Z J Psychiatry"},{"key":"96_CR7","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1080\/13607860500090078","volume":"9","author":"P Cuijpers","year":"2005","unstructured":"Cuijpers P: Depressive disorders in caregivers of dementia patients: a systematic review. Aging Ment Health. 2005, 9: 325-330. 10.1080\/13607860500090078.","journal-title":"Aging Ment Health"},{"key":"96_CR8","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1136\/bmj.312.7036.947","volume":"312","author":"CG Ballard","year":"1996","unstructured":"Ballard CG, Eastwood C, Gahir M, Wilcock G: A follow up study of depression in the carers of dementia sufferers. BMJ. 1996, 312: 947-","journal-title":"BMJ"},{"key":"96_CR9","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1177\/153331750401900202","volume":"19","author":"RL Akkerman","year":"2004","unstructured":"Akkerman RL, Ostwald SK: Reducing anxiety in Alzheimer's disease family caregivers: the effectiveness of a nine-week cognitive-behavioral intervention. Am J Alzheimers Dis Other Demen. 2004, 19: 117-123. 10.1177\/153331750401900202.","journal-title":"Am J Alzheimers Dis Other Demen"},{"key":"96_CR10","volume-title":"Family Caregiving in the US: Findings from a national survey.","author":"NA Caregiving","year":"1997","unstructured":"AARP, Caregiving NA: Family Caregiving in the US: Findings from a national survey. 1997, Bethesda, MD"},{"key":"96_CR11","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1037\/0021-843X.110.4.573","volume":"110","author":"S Robinson-Whelen","year":"2001","unstructured":"Robinson-Whelen S, Tada Y, MacCallum RC, McGuire L, Kiecolt-Glaser JK: Long-term caregiving: what happens when it ends?. J Abnorm Psychol. 2001, 110: 573-584. 10.1037\/0021-843X.110.4.573.","journal-title":"J Abnorm Psychol"},{"key":"96_CR12","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1002\/gps.1322","volume":"20","author":"H Brodaty","year":"2005","unstructured":"Brodaty H, Thomson C, Thompson C, Fine M: Why caregivers of people with dementia and memory loss don't use services. Int J Geriatr Psychiatry. 2005, 20: 537-546. 10.1002\/gps.1322.","journal-title":"Int J Geriatr Psychiatry"},{"key":"96_CR13","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1093\/geront\/42.3.356","volume":"42","author":"S Sorensen","year":"2002","unstructured":"Sorensen S, Pinquart M, Duberstein P: How effective are interventions with caregivers? An updated meta-analysis. Gerontologist. 2002, 42: 356-372.","journal-title":"Gerontologist"},{"key":"96_CR14","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1034\/j.1600-0579.2003.00210.x","volume":"51","author":"H Brodaty","year":"2003","unstructured":"Brodaty H, Green A, Koschera A: Meta-analysis of psychosocial interventions for caregivers of people with dementia. J Am Geriatr Soc. 2003, 51: 657-664. 10.1034\/j.1600-0579.2003.00210.x.","journal-title":"J Am Geriatr Soc"},{"key":"96_CR15","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1891\/0739-6686.20.1.149","volume":"20","author":"GJ Acton","year":"2002","unstructured":"Acton GJ, Winter MA: Interventions for family members caring for an elder with dementia. Annu Rev Nurs Res. 2002, 20: 149-179.","journal-title":"Annu Rev Nurs Res"},{"key":"96_CR16","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1093\/geront\/31.1.9","volume":"31","author":"CJ Whitlatch","year":"1991","unstructured":"Whitlatch CJ, Zarit SH, von Eye A: Efficacy of interventions with caregivers: a reanalysis. Gerontologist. 1991, 31: 9-14.","journal-title":"Gerontologist"},{"key":"96_CR17","doi-asserted-by":"publisher","first-page":"850","DOI":"10.1176\/appi.ajp.161.5.850","volume":"161","author":"MS Mittelman","year":"2004","unstructured":"Mittelman MS, Roth DL, Coon DW, Haley WE: Sustained benefit of supportive intervention for depressive symptoms in caregivers of patients with Alzheimer's disease. Am J Psychiatry. 2004, 161: 850-856. 10.1176\/appi.ajp.161.5.850.","journal-title":"Am J Psychiatry"},{"key":"96_CR18","doi-asserted-by":"publisher","first-page":"792","DOI":"10.1093\/geront\/35.6.792","volume":"35","author":"MS Mittelman","year":"1995","unstructured":"Mittelman MS, Ferris SH, Shulman E, Steinberg G, Ambinder A, Mackell JA, Cohen J: A comprehensive support program: effect on depression in spouse-caregivers of AD patients. Gerontologist. 1995, 35: 792-802.","journal-title":"Gerontologist"},{"key":"96_CR19","doi-asserted-by":"publisher","first-page":"1725","DOI":"10.1001\/jama.1996.03540210033030","volume":"276","author":"MS Mittelman","year":"1996","unstructured":"Mittelman MS, Ferris SH, Shulman E, Steinberg G, Levin B: A family intervention to delay nursing home placement of patients with Alzheimer disease. A randomized controlled trial. JAMA. 1996, 276: 1725-1731. 10.1001\/jama.276.21.1725.","journal-title":"JAMA"},{"key":"96_CR20","doi-asserted-by":"publisher","first-page":"1592","DOI":"10.1212\/01.wnl.0000242727.81172.91","volume":"67","author":"MS Mittelman","year":"2006","unstructured":"Mittelman MS, Haley WE, Clay OJ, Roth DL: Improving caregiver well-being delays nursing home placement of patients with Alzheimer disease. Neurology. 2006, 67: 1592-1599. 10.1212\/01.wnl.0000242727.81172.91.","journal-title":"Neurology"},{"key":"96_CR21","volume-title":"Counseling the Alzheimer's caregiver: A resource for health care professionals","author":"MS Mittelman","year":"2003","unstructured":"Mittelman MS, Epstein C, Pierzchala A: Counseling the Alzheimer's caregiver: A resource for health care professionals. 2003, Chicago: AMA Press"},{"key":"96_CR22","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1017\/S104161020300927X","volume":"15 Suppl 1","author":"MS Mittelman","year":"2003","unstructured":"Mittelman MS: Psychosocial intervention for dementia caregivers: what can it accomplish?. Int Psychogeriatr. 2003, 15 Suppl 1: 247-249. 10.1017\/S104161020300927X.","journal-title":"Int Psychogeriatr"},{"key":"96_CR23","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890423349","volume-title":"Diagnostic and statistical manual of mental disorders. fourth edition","author":"AP Association","year":"2000","unstructured":"Association AP: Diagnostic and statistical manual of mental disorders. fourth edition. 2000, Washington DC, American Psychiatric Association, fourth edition","edition":"fourth edition"},{"key":"96_CR24","first-page":"22","volume":"59 Suppl 20","author":"DV Sheehan","year":"1998","unstructured":"Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, Hergueta T, Baker R, Dunbar GC: The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry. 1998, 59 Suppl 20: 22-33.","journal-title":"J Clin Psychiatry"},{"key":"96_CR25","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1177\/014662167700100306","volume":"1","author":"LS Radloff","year":"1977","unstructured":"Radloff LS: The CES-D Scale: a Self -Report Depression Scale for Research in the General Population. Applied Psychological Measurement. 1977, 1: 385-401. 10.1177\/014662167700100306.","journal-title":"Applied Psychological Measurement"},{"key":"96_CR26","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","volume":"67","author":"AS Zigmond","year":"1983","unstructured":"Zigmond AS, Snaith RP: The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983, 67: 361-370. 10.1111\/j.1600-0447.1983.tb09716.x.","journal-title":"Acta Psychiatr Scand"},{"key":"96_CR27","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1017\/S0033291796004382","volume":"27","author":"P Spinhoven","year":"1997","unstructured":"Spinhoven P, Ormel J, Sloekers PP, Kempen GI, Speckens AE, Van Hemert AM: A validation study of the Hospital Anxiety and Depression Scale (HADS) in different groups of Dutch subjects. Psychol Med. 1997, 27: 363-370. 10.1017\/S0033291796004382.","journal-title":"Psychol Med"},{"key":"96_CR28","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1111\/j.1532-5415.1999.tb04588.x","volume":"47","author":"MJ Vernooij-Dassen","year":"1999","unstructured":"Vernooij-Dassen MJ, Felling AJ, Brummelkamp E, Dauzenberg MG, van den Bos GA, Grol R: Assessment of caregiver's competence in dealing with the burden of caregiving for a dementia patient: a Short Sense of Competence Questionnaire (SSCQ) suitable for clinical practice. J Am Geriatr Soc. 1999, 47: 256-257.","journal-title":"J Am Geriatr Soc"},{"key":"96_CR29","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1002\/nur.4770150406","volume":"15","author":"CW Given","year":"1992","unstructured":"Given CW, Given B, Stommel M, Collins C, King S, Franklin S: The caregiver reaction assessment (CRA) for caregivers to persons with chronic physical and mental impairments. Res Nurs Health. 1992, 15: 271-283. 10.1002\/nur.4770150406.","journal-title":"Res Nurs Health"},{"key":"96_CR30","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1191\/0269215504cr743oa","volume":"18","author":"NJ van Exel","year":"2004","unstructured":"van Exel NJ, Scholte op Reimer WJ, Brouwer WB, van den BB, Koopmanschap MA, van den Bos GA: Instruments for assessing the burden of informal caregiving for stroke patients in clinical practice: a comparison of CSI, CRA, SCQ and self-rated burden. Clin Rehabil. 2004, 18: 203-214. 10.1191\/0269215504cr723oa.","journal-title":"Clin Rehabil"},{"key":"96_CR31","volume-title":"How to score the SF-12 Physical and mental health summaries: a user's manual","author":"JE Ware","year":"1995","unstructured":"Ware JE, Kolinski M, Keller SD: How to score the SF-12 Physical and mental health summaries: a user's manual. 1995, Boston, The Health Institute, New England Medical Centre"},{"key":"96_CR32","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1097\/00005650-199603000-00003","volume":"34","author":"JE Ware Jr.","year":"1996","unstructured":"Ware JE, Kosinski M, Keller SD: A 12-item short form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care. 1996, 34: 220-233. 10.1097\/00005650-199603000-00003.","journal-title":"Med Care"},{"key":"96_CR33","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1177\/014662168500900307","volume":"9","author":"J Jong Gierveld","year":"1985","unstructured":"Jong Gierveld J, Kamphuis FH: The development of a Rasch-type Loneliness scale. Applied Psychological Measurement. 1985, 9: 289-299. 10.1177\/014662168500900307.","journal-title":"Applied Psychological Measurement"},{"key":"96_CR34","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","volume":"12","author":"MF Folstein","year":"1975","unstructured":"Folstein MF, Folstein SE, McHugh PR: \"Mini-mental state\". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975, 12: 189-198. 10.1016\/0022-3956(75)90026-6.","journal-title":"J Psychiatr Res"},{"key":"96_CR35","doi-asserted-by":"publisher","first-page":"2308","DOI":"10.1212\/WNL.44.12.2308","volume":"44","author":"JL Cummings","year":"1994","unstructured":"Cummings JL, Mega M, Gray K, Rosenberg-Thompson S, Carusi DA, Gornbein J: The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia. Neurology. 1994, 44: 2308-2314.","journal-title":"Neurology"},{"key":"96_CR36","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1093\/geront\/9.3_Part_1.179","volume":"9","author":"MP Lawton","year":"1969","unstructured":"Lawton MP, Brody EM: Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist. 1969, 9: 179-186.","journal-title":"Gerontologist"},{"key":"96_CR37","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1001\/jama.1963.03060120024016","volume":"185","author":"S Katz","year":"1963","unstructured":"Katz S, FORD AB, MOSKOWITZ RW, JACKSON BA, JAFFE MW: Studies of illness in the aged. The index of ADL: a standardized measure of biological and psychosocial function. JAMA. 1963, 185: 914-919.","journal-title":"JAMA"},{"key":"96_CR38","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1111\/j.1532-5415.1999.tb03848.x","volume":"47","author":"MT Hoyl","year":"1999","unstructured":"Hoyl MT, Alessi CA, Harker JO, Josephson KR, Pietruszka FM, Koelfgen M, Mervis JR, Fitten LJ, Rubenstein LZ: Development and testing of a five-item version of the Geriatric Depression Scale. J Am Geriatr Soc. 1999, 47: 873-878.","journal-title":"J Am Geriatr Soc"},{"key":"96_CR39","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1097\/01.mlr.0000135827.18610.0d","volume":"42","author":"JE Brazier","year":"2004","unstructured":"Brazier JE, Roberts J: The estimation of a preference-based measure of health from the SF-12. Med Care. 2004, 42: 851-859. 10.1097\/01.mlr.0000135827.18610.0d.","journal-title":"Med Care"},{"key":"96_CR40","doi-asserted-by":"publisher","first-page":"443","DOI":"10.2165\/00019053-200220070-00002","volume":"20","author":"JB Oostenbrink","year":"2002","unstructured":"Oostenbrink JB, Koopmanschap MA, Rutten FF: Standardisation of costs: the Dutch Manual for Costing in economic evaluations. Pharmacoeconomics. 2002, 20: 443-454. 10.2165\/00019053-200220070-00002.","journal-title":"Pharmacoeconomics"},{"key":"96_CR41","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/0167-6296(94)00044-5","volume":"14","author":"MA Koopmanschap","year":"1995","unstructured":"Koopmanschap MA, Rutten FF, van Ineveld BM, van Roijen L: The friction cost method for measuring indirect costs of disease. J Health Econ. 1995, 14: 171-189. 10.1016\/0167-6296(94)00044-5.","journal-title":"J Health Econ"},{"key":"96_CR42","volume-title":"Handleiding voor kostenonderzoek: Methoden en standaard kostprijzen voor economische evaluaties in de gezondheidszorg","author":"JB Oostenbrink","year":"2004","unstructured":"Oostenbrink JB, Bouwmans CAM, Koopmanschap MA, Rutten FF: Handleiding voor kostenonderzoek: Methoden en standaard kostprijzen voor economische evaluaties in de gezondheidszorg. 2004, Diemen, College voor Zorgverzekeringen, Geactualiseerde versie 2004","edition":"Geactualiseerde"},{"key":"96_CR43","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4899-4541-9","volume-title":"An introduction to the bootstrap","author":"B Efron","year":"1993","unstructured":"Efron B, Tibshirani RJ: An introduction to the bootstrap. 1993, New York London, Chapman & Hall"},{"key":"96_CR44","doi-asserted-by":"publisher","first-page":"1447","DOI":"10.1002\/(SICI)1097-0258(19960715)15:13<1447::AID-SIM267>3.0.CO;2-V","volume":"15","author":"MA Chaudhary","year":"1996","unstructured":"Chaudhary MA, Stearns SC: Estimating confidence intervals for cost-effectiveness ratios: an example from a randomized trial. Stat Med. 1996, 15: 1447-1458. 10.1002\/(SICI)1097-0258(19960715)15:13<1447::AID-SIM267>3.0.CO;2-V.","journal-title":"Stat Med"}],"container-title":["BMC Geriatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2318-8-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2318-8-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2318-8-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2318-8-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,22]],"date-time":"2019-01-22T02:37:36Z","timestamp":1548124656000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcgeriatr.biomedcentral.com\/articles\/10.1186\/1471-2318-8-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1,21]]},"references-count":44,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["96"],"URL":"https:\/\/doi.org\/10.1186\/1471-2318-8-2","relation":{},"ISSN":["1471-2318"],"issn-type":[{"value":"1471-2318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,1,21]]},"article-number":"2"}}