{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T17:36:00Z","timestamp":1696613760853},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2012,3,25]],"date-time":"2012-03-25T00:00:00Z","timestamp":1332633600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Hematol"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1186\/1471-2326-12-3","type":"journal-article","created":{"date-parts":[[2012,3,25]],"date-time":"2012-03-25T08:13:58Z","timestamp":1332663238000},"source":"Crossref","is-referenced-by-count":2,"title":["Hemoglobin E syndromes in Pakistani population"],"prefix":"10.1186","volume":"12","author":[{"given":"Bushra","family":"Moiz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mashhooda Rasool","family":"Hashmi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amna","family":"Nasir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anila","family":"Rashid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tariq","family":"Moatter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,3,25]]},"reference":[{"issue":"3120","key":"54_CR1","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1126\/science.120.3120.605","volume":"120","author":"AI Chernoff","year":"1954","unstructured":"Chernoff AI, Minnich V, Chongchareonsuk S: Hemoglobin E, a hereditary abnormality of human hemoglobin. Science. 1954, 120 (3120): 605-606. 10.1126\/science.120.3120.605.","journal-title":"Science"},{"issue":"4","key":"54_CR2","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1182\/blood.V100.4.1172.h81602001172_1172_1176","volume":"100","author":"K Chotivanich","year":"2002","unstructured":"Chotivanich K, Udomsangpetch R, Pattanapanyasat K, Chierakul W, Simpson J, Looareesuwan S, White N: Hemoglobin E: a balanced polymorphism protective against high parasitemias and thus severe P falciparum malaria. Blood. 2002, 100 (4): 1172-1176.","journal-title":"Blood"},{"issue":"8","key":"54_CR3","first-page":"704","volume":"79","author":"DJ Weatherall","year":"2001","unstructured":"Weatherall DJ, Clegg JB: Inherited haemoglobin disorders: an increasing global health problem. Bull World Health Organ. 2001, 79 (8): 704-712.","journal-title":"Bull World Health Organ"},{"issue":"3-4","key":"54_CR4","doi-asserted-by":"crossref","first-page":"112","DOI":"10.14238\/pi15.3-4.1975.112-9","volume":"15","author":"JH Jonxis","year":"1975","unstructured":"Jonxis JH: Haemoglobinopathies and their occurrence in South East Asia. Paediatr Indones. 1975, 15 (3-4): 112-119.","journal-title":"Paediatr Indones"},{"issue":"1","key":"54_CR5","first-page":"39","volume":"137","author":"E Katsanis","year":"1987","unstructured":"Katsanis E, Luke KH, Hsu E, Yates JR: Hemoglobin E: a common hemoglobinopathy among children of Southeast Asian origin. CMAJ. 1987, 137 (1): 39-42.","journal-title":"CMAJ"},{"key":"54_CR6","doi-asserted-by":"publisher","DOI":"10.1002\/9780470988787","volume-title":"Hemoglobinopathy diagnosis","author":"JB Bain","year":"2006","unstructured":"Bain JB: Hemoglobinopathy diagnosis. 2006, London: Blackwell Publishing, second","edition":"second"},{"issue":"4","key":"54_CR7","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1080\/10245330701255247","volume":"12","author":"B Kishore","year":"2007","unstructured":"Kishore B, Khare P, Gupta RJ, Bisht S, Majumdar K: Hemoglobin E disease in North Indian population: a report of 11 cases. Hematology. 2007, 12 (4): 343-347. 10.1080\/10245330701255247.","journal-title":"Hematology"},{"key":"54_CR8","first-page":"171","volume":"64","author":"KA Khaleque","year":"1961","unstructured":"Khaleque KA: Haemoglobin E, thalassaemia, and their combination in a Muslim family of East Pakistan. J Trop Med Hyg. 1961, 64: 171-174.","journal-title":"J Trop Med Hyg"},{"issue":"1","key":"54_CR9","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1093\/tropej\/36.1.43","volume":"36","author":"CK Nguyen","year":"1990","unstructured":"Nguyen CK, Le TT, Duong BT, Dinh PH, Ta TH, Tran HH: Beta-thalassemia\/haemoglobin E disease in Vietnam. J Trop Pediatr. 1990, 36 (1): 43-45.","journal-title":"J Trop Pediatr"},{"issue":"2","key":"54_CR10","first-page":"123","volume":"36","author":"E George","year":"1984","unstructured":"George E, Khuziah R: Malays with thalassaemia in West Malaysia. Trop Geogr Med. 1984, 36 (2): 123-125.","journal-title":"Trop Geogr Med"},{"issue":"4","key":"54_CR11","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1002\/ajh.2830250411","volume":"25","author":"NA Lachant","year":"1987","unstructured":"Lachant NA: Hemoglobin E: an emerging hemoglobinopathy in the United States. Am J Hematol. 1987, 25 (4): 449-462. 10.1002\/ajh.2830250411.","journal-title":"Am J Hematol"},{"issue":"10","key":"54_CR12","first-page":"1092","volume":"88","author":"S Fucharoen","year":"2003","unstructured":"Fucharoen S, Sanchaisuriya K, Fucharoen G, Panyasai S, Devenish R, Luy L: Interaction of hemoglobin E and several forms of alpha-thalassemia in Cambodian families. Haematologica. 2003, 88 (10): 1092-1098.","journal-title":"Haematologica"},{"issue":"2","key":"54_CR13","doi-asserted-by":"publisher","first-page":"698","DOI":"10.1016\/0006-291X(90)92147-R","volume":"170","author":"G Fucharoen","year":"1990","unstructured":"Fucharoen G, Fucharoen S, Jetsrisuparb A, Fukumaki Y: Molecular basis of HbE-beta-thalassemia and the origin of HbE in northeast Thailand: identification of one novel mutation using amplified DNA from buffy coat specimens. Biochem Biophys Res Commun. 1990, 170 (2): 698-704. 10.1016\/0006-291X(90)92147-R.","journal-title":"Biochem Biophys Res Commun"},{"key":"54_CR14","first-page":"79","volume-title":"Hematology Am Soc Hematol Educ Program","author":"E Vichinsky","year":"2007","unstructured":"Vichinsky E: Hemoglobin e syndromes. Hematology Am Soc Hematol Educ Program. 2007, 79-83."},{"issue":"5","key":"54_CR15","first-page":"364","volume":"82","author":"G Fucharoen","year":"2004","unstructured":"Fucharoen G, Sanchaisuriya K, Sae-ung N, Dangwibul S, Fucharoen S: A simplified screening strategy for thalassaemia and haemoglobin E in rural communities in south-east Asia. Bull World Health Organ. 2004, 82 (5): 364-372.","journal-title":"Bull World Health Organ"},{"issue":"10","key":"54_CR16","doi-asserted-by":"publisher","first-page":"1736","DOI":"10.1373\/clinchem.2004.034991","volume":"50","author":"A Joutovsky","year":"2004","unstructured":"Joutovsky A, Hadzi-Nesic J, Nardi MA: HPLC retention time as a diagnostic tool for hemoglobin variants and hemoglobinopathies: a study of 60000 samples in a clinical diagnostic laboratory. Clin Chem. 2004, 50 (10): 1736-1747. 10.1373\/clinchem.2004.034991.","journal-title":"Clin Chem"},{"issue":"2","key":"54_CR17","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1159\/000041025","volume":"103","author":"SC Wong","year":"2000","unstructured":"Wong SC, Aw TC, Suri R, Wong CK, Plaseska D, Efremov GD: Differential diagnosis of Hb EE and Hb E-beta(0)-thalassemia by protein and DNA analyses. Acta Haematol. 2000, 103 (2): 84-89. 10.1159\/000041025.","journal-title":"Acta Haematol"},{"issue":"1","key":"54_CR18","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1111\/j.1751-553X.2007.01006.x","volume":"31","author":"S Sangkitporn","year":"2009","unstructured":"Sangkitporn S, Sangkitporn SK, Sangnoi A, Duangruang S: Detection of Hb E mutation (beta(26), GAG-AAG, Glu-Lys) using allelic discrimination analysis. Int J Lab Hematol. 2009, 31 (1): 74-80. 10.1111\/j.1751-553X.2007.01006.x.","journal-title":"Int J Lab Hematol"},{"issue":"4","key":"54_CR19","first-page":"855","volume":"33","author":"R Ghani","year":"2002","unstructured":"Ghani R, Manji MA, Ahmed N: Hemoglobinopathies among five major ethnic groups in Karachi, Pakistan. Southeast Asian J Trop Med Public Health. 2002, 33 (4): 855-861.","journal-title":"Southeast Asian J Trop Med Public Health"},{"issue":"10","key":"54_CR20","first-page":"246","volume":"41","author":"Z Rehman","year":"1991","unstructured":"Rehman Z, Saleem M, Alvi AA, Anwar M, Ahmed PA, Ahmad M: Alpha-thalassaemia: prevalence and pattern in northern Pakistan. J Pak Med Assoc. 1991, 41 (10): 246-247.","journal-title":"J Pak Med Assoc"},{"issue":"2","key":"54_CR21","first-page":"32","volume":"42","author":"MF Khattak","year":"1992","unstructured":"Khattak MF, Saleem M: Prevalence of heterozygous beta-thalassemia in northern areas of Pakistan. J Pak Med Assoc. 1992, 42 (2): 32-34.","journal-title":"J Pak Med Assoc"},{"issue":"3","key":"54_CR22","first-page":"476","volume":"94","author":"S Ahmed","year":"1996","unstructured":"Ahmed S, Petrou M, Saleem M: Molecular genetics of beta-thalassaemia in Pakistan: a basis for prenatal diagnosis. Br J Haematol. 1996, 94 (3): 476-482.","journal-title":"Br J Haematol"},{"issue":"8","key":"54_CR23","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1007\/s00277-008-0495-7","volume":"87","author":"NK Hashmi","year":"2008","unstructured":"Hashmi NK, Moiz B, Nusrat M, Hashmi MR: Chromatographic analysis of Hb S for the diagnosis of various sickle cell disorders in Pakistan. Ann Hematol. 2008, 87 (8): 639-645. 10.1007\/s00277-008-0495-7.","journal-title":"Ann Hematol"},{"issue":"4","key":"54_CR24","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1097\/00043426-198824000-00009","volume":"10","author":"ST Dawod","year":"1988","unstructured":"Dawod ST, Abulaban M, Kamel K, Huisman TH: Hemoglobin D-beta (0) thalassemia. A case report and family study. Am J Pediatr Hematol Oncol. 1988, 10 (4): 316-318. 10.1097\/00043426-198824000-00009.","journal-title":"Am J Pediatr Hematol Oncol"},{"issue":"14-15","key":"54_CR25","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.1016\/j.clinbiochem.2008.06.015","volume":"41","author":"B Moiz","year":"2008","unstructured":"Moiz B, Hashmi MR, Sadaf S: Performance evaluation of ion exchange and affinity chromatography for HbA1c estimation in diabetic patients with HbD: a study of 129 samples. Clin Biochem. 2008, 41 (14-15): 1204-1210. 10.1016\/j.clinbiochem.2008.06.015.","journal-title":"Clin Biochem"},{"issue":"5","key":"54_CR26","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1007\/s00277-007-0431-2","volume":"87","author":"B Moiz","year":"2008","unstructured":"Moiz B, Moatter T, Hashmi MR, Hashmi N, Kauser T, Nasir A, Khurshid M: Identification of hemoglobin Q India (alpha 1-64 Asp-His) through ARMS-PCR. First report from Pakistan. Ann Hematol. 2008, 87 (5): 385-389. 10.1007\/s00277-007-0431-2.","journal-title":"Ann Hematol"},{"issue":"1","key":"54_CR27","doi-asserted-by":"publisher","first-page":"31","DOI":"10.3109\/03630260009002271","volume":"24","author":"SN Khan","year":"2000","unstructured":"Khan SN, Butt FI, Riazuddin S, Galanello R: Hb Sallanches [alpha104(G11) Cys- > Tyr]: a rare alpha2-globin chain variant found in the homozygous state in three members of a Pakistani family. Hemoglobin. 2000, 24 (1): 31-35. 10.3109\/03630260009002271.","journal-title":"Hemoglobin"},{"issue":"9","key":"54_CR28","doi-asserted-by":"crossref","first-page":"3199","DOI":"10.1182\/blood.V94.9.3199","volume":"94","author":"DC Rees","year":"1999","unstructured":"Rees DC, Porter JB, Clegg JB, Weatherall DJ: Why are hemoglobin F levels increased in HbE\/beta thalassemia?. Blood. 1999, 94 (9): 3199-3204.","journal-title":"Blood"},{"issue":"10","key":"54_CR29","first-page":"498","volume":"54","author":"TS Shamsi","year":"2004","unstructured":"Shamsi TS: Beta-thalassaemia-a major health problem in Pakistan. J Pak Med Assoc. 2004, 54 (10): 498-","journal-title":"J Pak Med Assoc"},{"issue":"11","key":"54_CR30","first-page":"1677","volume":"9","author":"STR Intorasoot","year":"2008","unstructured":"Intorasoot STR, Tragoolpua K, Chottayaporn M: Hemoglobin E detection using PCR with confronting two pair primers. J Med Assoc Thai. 2008, 9 (11): 1677-1680.","journal-title":"J Med Assoc Thai"},{"issue":"2","key":"54_CR31","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1136\/jmg.24.2.110","volume":"24","author":"SL Thein","year":"1987","unstructured":"Thein SL, Lynch JR, Old JM, Weatherall DJ: Direct detection of haemoglobin E with MnlI. J Med Genet. 1987, 24 (2): 110-111. 10.1136\/jmg.24.2.110.","journal-title":"J Med Genet"},{"issue":"6","key":"54_CR32","doi-asserted-by":"crossref","first-page":"2141","DOI":"10.1182\/blood.V92.6.2141","volume":"92","author":"DC Rees","year":"1998","unstructured":"Rees DC, Clegg JB, Weatherall DJ: Is hemoglobin instability important in the interaction between hemoglobin E and beta thalassemia?. Blood. 1998, 92 (6): 2141-2146.","journal-title":"Blood"},{"issue":"12","key":"54_CR33","first-page":"284","volume":"44","author":"IH Thaver","year":"1994","unstructured":"Thaver IH, Baig L, Inam ul H, Iqbal R: Anaemia in children: Part II. Should primary health care providers prescribe iron supplements by the observation and presence of assumed symptoms?. J Pak Med Assoc. 1994, 44 (12): 284-285.","journal-title":"J Pak Med Assoc"},{"issue":"4","key":"54_CR34","first-page":"90","volume":"44","author":"SA Karim","year":"1994","unstructured":"Karim SA, Khurshid M, Memon AM, Jafarey SN: Anaemia in pregnancy-its cause in the underprivileged class of Karachi. J Pak Med Assoc. 1994, 44 (4): 90-92.","journal-title":"J Pak Med Assoc"},{"issue":"7","key":"54_CR35","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1185\/03007998709112407","volume":"10","author":"P Hamedani","year":"1987","unstructured":"Hamedani P, Hashmi KZ, Manji M: Iron depletion and anaemia: prevalence, consequences, diagnostic and therapeutic implications in a developing Pakistani population. Curr Med Res Opin. 1987, 10 (7): 480-485. 10.1185\/03007998709112407.","journal-title":"Curr Med Res Opin"},{"issue":"1","key":"54_CR36","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1080\/10245330310001638983","volume":"9","author":"S Tyagi","year":"2004","unstructured":"Tyagi S, Pati HP, Choudhry VP, Saxena R: Clinico-haematological profile of HbE syndrome in adults and children. Hematology. 2004, 9 (1): 57-60. 10.1080\/10245330310001638983.","journal-title":"Hematology"}],"container-title":["BMC Blood Disorders"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2326-12-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2326-12-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2326-12-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2326-12-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,4]],"date-time":"2020-07-04T20:21:31Z","timestamp":1593894091000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmchematol.biomedcentral.com\/articles\/10.1186\/1471-2326-12-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3,25]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["54"],"URL":"https:\/\/doi.org\/10.1186\/1471-2326-12-3","relation":{},"ISSN":["1471-2326"],"issn-type":[{"value":"1471-2326","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,3,25]]},"article-number":"3"}}