{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T16:58:43Z","timestamp":1758819523286},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2010,3,12]],"date-time":"2010-03-12T00:00:00Z","timestamp":1268352000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"published-print":{"date-parts":[[2010,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Although, in South Korea, human immunodeficiency virus\/acquired immunodeficiency syndrome(HIV\/AIDS) keeps increasing and tuberculosis(TB) burden is still significant, there have been few reports on TB\/HIV cases. In this study, we investigated the burden and characteristics of TB\/HIV patients in South Korea, an area with intermediate burden of TB and a low prevalent area with HIV\/AIDS.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>We identified patients with TB and cases with HIV between January 1 2001 and December 31 2005, from nationwide reporting system (TBnet and HIV\/AIDS registry) through an electronic record linkage method. A questionnaire survey was also conducted and determined the rate of diagnosis of HIV among TB cases in public health units in 2005.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>The number of cases with both HIV and TB was 137 (0.07% among 197,562 TB cases) and the newly detected TB\/HIV cases per 100,000 population was increasing annually: 2001, 0.025; 2002, 0.031; 2003, 0.025; 2004, 0.071; 2005, 0.095. Males between 20 and 59 years of age accounted for 87.6% of TB\/HIV patients. Compared with patients with TB alone, those with TB\/HIV had a higher percentage of extrapulmonary TB (8.0% vs 19.0%; p &lt; 0.0001). The standardized prevalence ratio (SPR) of HIV among patients with TB was 18.46 (95% CI, 15.50-21.83). SPR of HIV among male TB patients aged 20-59 and extrapulmonary TB cases was 39.64 (95% CI, 32.87-47.40) and 43.21 (95% CI, 28.22-63.31) respectively. Through a questionnaire survey of public health units, six patients (0.08%) were confirmed as having HIV among 7,871 TB patients in public health centers in 2005, which is similar to the result from the study through nationwide reporting systems.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>The prevalence rate of TB\/HIV patients is still low but increasing in South Korea. Physicians should consider performing HIV tests among TB patients, especially in higher-risk groups, such as young males with extrapulmonary TB in South Korea.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1471-2334-10-66","type":"journal-article","created":{"date-parts":[[2010,5,14]],"date-time":"2010-05-14T12:00:20Z","timestamp":1273838420000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["The burden and characteristics of tuberculosis\/human immunodeficiency virus (TB\/HIV) in South Korea: a study from a population database and a survey"],"prefix":"10.1186","volume":"10","author":[{"given":"Chang-Hoon","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji-young","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dae-Kyu","family":"Oh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mee-Kyung","family":"Kee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eunjung","family":"Oh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jung-wook","family":"An","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinhyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heonsook","family":"Do","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hee-Jin","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Soon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hwahyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeong-Gu","family":"Nam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,3,12]]},"reference":[{"key":"1046_CR1","volume-title":"Global Tuberculosis Control: Surveillance, Planing, Financing: WHO report 2006","author":"World Health Organization","year":"2008","unstructured":"World Health Organization: Global Tuberculosis Control: Surveillance, Planing, Financing: WHO report 2006. 2008, Geneva, Switzerland: World Health Organization"},{"key":"1046_CR2","volume-title":"AIDS epdemic update 2007","author":"The Joint United Nations Programme on HIV\/AIDS","year":"2007","unstructured":"The Joint United Nations Programme on HIV\/AIDS: AIDS epdemic update 2007. 2007, Geneva, Switzerland: Joint United Nations Programme on HIV\/AIDS (UNAIDS) and World Health Organization (WHO)"},{"issue":"8678-8679","key":"1046_CR3","first-page":"1502","volume":"2","author":"G Di Perri","year":"1989","unstructured":"Di Perri G, Cruciani M, Danzi MC, Luzzati R, De Checchi G, Malena M, Pizzighella S, Mazzi R, Solbiati M, Concia E, et al: Nosocomial epidemic of active tuberculosis among HIV-infected patients. 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