{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T13:01:40Z","timestamp":1780923700353,"version":"3.54.1"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2011,10,31]],"date-time":"2011-10-31T00:00:00Z","timestamp":1320019200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>The incidence rate of <jats:italic>Nocardia<\/jats:italic> keratitis is increasing, with new species identified thanks to molecular methods. We herein report a case of <jats:italic>Nocardia transvalensis<\/jats:italic> keratitis, illustrating this emerging pathology among travellers returning from Asia.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Case presentation<\/jats:title>\n            <jats:p>A 23-year-old man presented with a 10-week history of ocular pain, redness, and blurred vision in his right eye following a projectile foreign body impacting the cornea while motor biking in Tha\u00efland. At presentation, a central epithelial defect with a central whitish stromal infiltrate associated with pinhead satellite infiltrates was observed. Identification with 16S rRNA PCR sequencing and microbiological culture of corneal scraping and revealed <jats:italic>N. transvalensis<\/jats:italic> as the causative organism. Treatment was initiated with intensive topical amikacin, oral ketoconazole and oral doxycycline. After a four-week treatment period, the corneal infiltrate decreased so that only a faint subepithelial opacity remained.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>\n              <jats:italic>Nocardia<\/jats:italic> organisms should be suspected as the causative agent of any case of keratitis in travelers returning from Asia. With appropriate therapy, <jats:italic>Nocardia<\/jats:italic> keratitis resolves, resulting in good visual outcome.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1471-2334-11-296","type":"journal-article","created":{"date-parts":[[2011,12,8]],"date-time":"2011-12-08T20:33:12Z","timestamp":1323376392000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Nocardia transvalensis keratitis: an emerging pathology among travelers returning from Asia"],"prefix":"10.1186","volume":"11","author":[{"given":"Elodie","family":"Trichet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phan","family":"Cohen-Bacrie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Conrath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Drancourt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Hoffart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2011,10,31]]},"reference":[{"key":"1653_CR1","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1097\/ICU.0b013e32832c3bcc","volume":"20","author":"P Lalitha","year":"2009","unstructured":"Lalitha P: Nocardia keratitis. 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