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We analyzed <jats:italic>P. rettgeri<\/jats:italic> clinical isolates with resistance to carbapenems and aminoglycosides in a hospital in Nepal.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>Five clinical isolates of multidrug-resistant <jats:italic>P. rettgeri<\/jats:italic> were obtained in a hospital in Nepal. Antimicrobial susceptibilities were determined using the microdilution method and entire genomes were sequenced to determine drug-resistant genes. Epidemiological analysis was performed by pulsed-field gel electrophoresis.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Four of the 5 isolates were resistant to carbapenems (imipenem and meropenem), with MICs \u226516\u00a0mg\/L, with the remaining isolate showing intermediate resistance to imipenem, with an MIC of 2\u00a0mg\/L and susceptibility to meropenem with an MIC \u22641\u00a0mg\/L. All 5 isolates had <jats:italic>bla<\/jats:italic>\n              <jats:sub>VEB-1<\/jats:sub>. Of the 4 carbapenem-resistant strains, 3 had <jats:italic>bla<\/jats:italic>\n              <jats:sub>NDM-1<\/jats:sub> and 1 had <jats:italic>bla<\/jats:italic>\n              <jats:sub>OXA-72<\/jats:sub>. All isolates were highly resistant to aminoglycosides (MICs \u22651,024\u00a0mg\/L) and harbored <jats:italic>armA<\/jats:italic>. As the result of pulsed-field gel electrophoresis pattern analysis in the 5 <jats:italic>P. rettgeri<\/jats:italic> isolates, 4 had identical PFGE patterns and the fifth showed 95.7% similarity.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>This is the first report describing multidrug-resistant <jats:italic>P. rettgeri<\/jats:italic> strains harboring <jats:italic>bla<\/jats:italic>\n              <jats:sub>NDM-1<\/jats:sub> or <jats:italic>bla<\/jats:italic>\n              <jats:sub>OXA-72<\/jats:sub> and <jats:italic>armA<\/jats:italic> isolated from patients in Nepal.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1471-2334-14-56","type":"journal-article","created":{"date-parts":[[2014,2,3]],"date-time":"2014-02-03T06:00:58Z","timestamp":1391407258000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["NDM-1 Metallo-\u03b2-Lactamase and ArmA 16S rRNA methylase producing Providencia rettgeri clinical isolates in Nepal"],"prefix":"10.1186","volume":"14","author":[{"given":"Tatsuya","family":"Tada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tohru","family":"Miyoshi-Akiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajan K","family":"Dahal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manoj K","family":"Sah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Ohara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kayo","family":"Shimada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teruo","family":"Kirikae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bharat M","family":"Pokhrel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,2,3]]},"reference":[{"key":"3009_CR1","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1099\/00222615-47-7-629","volume":"47","author":"I Stock","year":"1998","unstructured":"Stock I, Wiedemann B: Natural antibiotic susceptibility of Providencia stuartii, P. rettgeri, P. alcalifaciens and P. rustigianii strains. 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