{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T16:45:50Z","timestamp":1791477950379,"version":"4.3.4"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2006,6,9]],"date-time":"2006-06-09T00:00:00Z","timestamp":1149811200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"published-print":{"date-parts":[[2006,12]]},"DOI":"10.1186\/1471-2334-6-96","type":"journal-article","created":{"date-parts":[[2006,6,9]],"date-time":"2006-06-09T18:29:48Z","timestamp":1149877788000},"source":"Crossref","is-referenced-by-count":23,"title":["Immuno-epidemiology of human Schistosoma haematobiuminfection: preferential IgG3 antibody responsiveness to a recombinant antigen dependent on age and parasite burden"],"prefix":"10.1186","volume":"6","author":[{"given":"Francisca","family":"Mutapi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takafira","family":"Mduluza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Gomez-Escobar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William F","family":"Gregory","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia","family":"Fernandez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Midzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rick M","family":"Maizels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2006,6,9]]},"reference":[{"key":"360_CR1","first-page":"3","volume-title":"WHO technical report series, 2nd report:the control of schistosomiasis","author":"WH Organisation","year":"1993","unstructured":"Organisation WH: WHO technical report series, 2nd report:the control of schistosomiasis. Edited by: WHO . 1993, 3-"},{"key":"360_CR2","unstructured":"Organisation WH: Initiative for Vaccine Research. Parasitic diseases-[\n                    http:\/\/www.who.int\/vaccine_research\/diseases\/soa_parasitic\/en\/index5.html\n                    \n                  ]"},{"key":"360_CR3","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1007\/PL00008562","volume":"86","author":"FG Abath","year":"2000","unstructured":"Abath FG, Xavier EM, Allen R, Gomes YM, Lucena-Silva N, Baliza M, Simpson AJ: Characterization of Sm13, a tegumental antigen of Schistosoma mansoni. Parasitol Res. 2000, 86: 745-752. 10.1007\/PL00008562.","journal-title":"Parasitol Res"},{"key":"360_CR4","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1590\/S0074-02761992000800012","volume":"87 Suppl 4","author":"AM Agnew","year":"1992","unstructured":"Agnew AM, Murare HM, Sandoval SN, de Jong N, Krijer FW, Deelder AM, Doenhoff MJ: The susceptibility of adult schistosomes to immune attrition. Mem Inst Oswaldo Cruz. 1992, 87 Suppl 4: 87-93.","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"360_CR5","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1111\/j.1365-3024.1993.tb00609.x","volume":"15","author":"AM Agnew","year":"1993","unstructured":"Agnew AM, Murare HM, Doenhoff MJ: Immune attrition of adult schistosomes. Parasite Immunol. 1993, 15: 261-271.","journal-title":"Parasite Immunol"},{"key":"360_CR6","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1126\/science.3317823","volume":"238","author":"A Capron","year":"1987","unstructured":"Capron A, Dessaint JP, Capron M, Ouma JH, Butterworth AE: Immunity to schistosomes: progress toward vaccine. Science. 1987, 238: 1065-1072.","journal-title":"Science"},{"key":"360_CR7","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/S0035-9203(34)90066-3","volume":"28","author":"AC Fisher","year":"1934","unstructured":"Fisher AC: A study of schistosomiaisis in the Stanleyville district of Congo. Transactions of the Royal Society of Tropical Medicine and Hygiene. 1934, 28: 277-306. 10.1016\/S0035-9203(34)90066-3.","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"key":"360_CR8","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1111\/j.1365-3024.1992.tb00029.x","volume":"14","author":"MEJ Woolhouse","year":"1992","unstructured":"Woolhouse MEJ: A theoretical framework for the immuno-epidemiology of helminth infection. Parasite Immunology. 1992, 14: 563-578.","journal-title":"Parasite Immunology"},{"key":"360_CR9","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1111\/pim.1993.15.10.583","volume":"15","author":"MEJ Woolhouse","year":"1993","unstructured":"Woolhouse MEJ: A theoreticl framework for immune responses and predisposition to helminth infection. Parasite Immunology. 1993, 15: 583-594.","journal-title":"Parasite Immunology"},{"key":"360_CR10","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1017\/S003118209600858X","volume":"114","author":"M Webster","year":"1997","unstructured":"Webster M, LibrandaRamirez BDL, Aligui GD, Olveda RM, Ouma JH, Kariuki HC, Kimani G, Olds GR, Fulford AJC, Butterworth AE, Dunne DW: The influence of sex and age on antibody isotype responses to Schistosoma mansoni and Schistosoma japonicum in human populations in Kenya and the Philippines. Parasitology. 1997, 114: 383-393. 10.1017\/S003118209600858X.","journal-title":"Parasitology"},{"key":"360_CR11","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1046\/j.1365-3156.1998.00234.x","volume":"3","author":"M Webster","year":"1998","unstructured":"Webster M, Roberts M, Fulford AJ, Marguerite M, Gallisot MC, Diagne M, Niang M, Riveau G, Capron A, Dunne DW: Human IgE responses to rSm22.6 are associated with infection intensity rather than age per se, in a recently established focus of Schistosomiais mansoni. Trop Med Int Health. 1998, 3: 318-326. 10.1046\/j.1365-3156.1998.00234.x.","journal-title":"Trop Med Int Health"},{"key":"360_CR12","doi-asserted-by":"publisher","first-page":"1232","DOI":"10.1093\/infdis\/173.5.1232","volume":"173","author":"GJ van Dam","year":"1996","unstructured":"van Dam GJ, Stelma FF, Gryseels B, Falcao Ferreira ST, Talla I, Niang M, Rotmans JP, Deelder AM: Antibody response patterns against Schistosoma mansoni in a recently exposed community in Senegal. J Infect Dis. 1996, 173: 1232-1241.","journal-title":"J Infect Dis"},{"key":"360_CR13","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1046\/j.1365-3024.1996.d01-78.x","volume":"18","author":"P Ndhlovu","year":"1996","unstructured":"Ndhlovu P, Cadman H, Vennervald BJ, Christensen NO, Chidimu N, Chandiwana SK: Age-related antibody profiles in Schistosoma haematobium in a rural community in Zimbabwe. Parasite Immunology. 1996, 18: 181-191. 10.1046\/j.1365-3024.1996.d01-78.x.","journal-title":"Parasite Immunology"},{"key":"360_CR14","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1046\/j.1365-3024.1997.d01-206.x","volume":"19","author":"F Mutapi","year":"1997","unstructured":"Mutapi F, Hagan P, Ndhlovu P, Woolhouse MEJ: Comparison of humoral responses to Schistosoma haematobium in areas with high and low levels of infection. Parasite Immunology. 1997, 19: 255-263. 10.1046\/j.1365-3024.1997.d01-206.x.","journal-title":"Parasite Immunology"},{"key":"360_CR15","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1046\/j.1365-3156.2003.01056.x","volume":"8","author":"CW Naus","year":"2003","unstructured":"Naus CW, Booth M, Jones FM, Kemijumbi J, Vennervald BJ, Kariuki CH, Ouma JH, Kabatereine NB, Dunne DW: The relationship between age, sex, egg-count and specific antibody responses against Schistosoma mansoni antigens in a Ugandan fishing community. Trop Med Int Health. 2003, 8: 561-568. 10.1046\/j.1365-3156.2003.01056.x.","journal-title":"Trop Med Int Health"},{"key":"360_CR16","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1590\/S0074-02761995000200025","volume":"90","author":"B Gryseels","year":"1995","unstructured":"Gryseels B, Stelma F, Talla I, Polman K, Vandam G, Sow S, Diaw M, Sturrock RF, Decam C, Niang M, Deelder AM: Immuno-epidemiology of Schistosoma mansoni infections in a recently exposed community in Senegal. Memorias do Instituto Oswaldo Cruz. 1995, 90: 271-276.","journal-title":"Memorias do Instituto Oswaldo Cruz"},{"key":"360_CR17","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/S0001-706X(02)00177-8","volume":"84","author":"LP Acosta","year":"2002","unstructured":"Acosta LP, Waine G, Aligui GD, Tiu WU, Olveda RM, McManus DP: Immune correlate study on human Schistosoma japonicum in a well-defined population in Leyte, Philippines: II. Cellular immune responses to S. japonicum recombinant and native antigens. Acta Trop. 2002, 84: 137-149. 10.1016\/S0001-706X(02)00177-8.","journal-title":"Acta Trop"},{"key":"360_CR18","doi-asserted-by":"publisher","first-page":"816","DOI":"10.1034\/j.1600-0463.2001.091203.x","volume":"109","author":"F Abebe","year":"2001","unstructured":"Abebe F, Gaarder PI, Petros B, Gundersen SG: Age and sex-related diffrences in antibody responses against Schistosoma mansoni soluble egg antigens in a cohort of school children in Ethiopia. APMIS. 2001, 109: 816-824. 10.1034\/j.1600-0463.2001.091203.x.","journal-title":"APMIS"},{"key":"360_CR19","doi-asserted-by":"publisher","first-page":"1545","DOI":"10.1016\/S0264-410X(97)00071-6","volume":"15","author":"MS Chan","year":"1997","unstructured":"Chan MS, Woolhouse MEJ, Bundy DAP: Human schistosomiasis: potential long term consequences of vaccination programmes. Vaccine. 1997, 15: 1545-1550. 10.1016\/S0264-410X(97)00071-6.","journal-title":"Vaccine"},{"key":"360_CR20","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1038\/351757a0","volume":"351","author":"MEJ Woolhouse","year":"1991","unstructured":"Woolhouse MEJ, Taylor P, Matanhire D, Chandiwana SK: Acquired immunity and epidemiology of Schistosoma haematobium. Nature. 1991, 351: 757-759. 10.1038\/351757a0.","journal-title":"Nature"},{"key":"360_CR21","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1017\/S003118209900534X","volume":"120","author":"MS Chan","year":"2000","unstructured":"Chan MS, Mutapi F, Woolhouse MEJ, Isham V: Stochastic simulation and detection of immunity to schistosome infection. Parasitology. 2000, 120: 161-169. 10.1017\/S003118209900534X.","journal-title":"Parasitology"},{"issue":"4","key":"360_CR22","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/S1473-3099(02)00240-2","volume":"2","author":"F Mutapi","year":"2002","unstructured":"Mutapi F, Roddam A: p-values for pathogens: statistical inference from infectious-disease data. Lancet Infect Dis. 2002, 2 (4): 219-230. 10.1016\/S1473-3099(02)00240-2.","journal-title":"Lancet Infect Dis"},{"key":"360_CR23","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1016\/0035-9203(94)90144-9","volume":"88","author":"MEJ Woolhouse","year":"1994","unstructured":"Woolhouse MEJ, Ndamba J, Bradely DJ: On the interpretation of intensity of infection data for Schistosoma haematobium. Transactions of the Royal Society of Tropical Medicine and Hygiene. 1994, 88: 520-526. 10.1016\/0035-9203(94)90144-9.","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"key":"360_CR24","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/0169-4758(94)90030-2","volume":"10","author":"MEJ Woolhouse","year":"1994","unstructured":"Woolhouse MEJ: Immunoepidemiology of human schistosomes: taking the theory into the field. Parasitology Today. 1994, 10: 196-202. 10.1016\/0169-4758(94)90030-2.","journal-title":"Parasitology Today"},{"key":"360_CR25","first-page":"1","volume":"12","author":"VV Clarke","year":"1966","unstructured":"Clarke VV: The influence of acquired resistance in the epidemiology of Bilharziasis. The Central African Journal of Medicine. 1966, 12: 1-30.","journal-title":"The Central African Journal of Medicine"},{"key":"360_CR26","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1111\/j.0141-9838.2004.00727.x","volume":"26","author":"RJ Quinnell","year":"2004","unstructured":"Quinnell RJ, Bethony J, Pritchard DI: The immunoepidemiology of human hookworm infection. Parasite Immunol. 2004, 26: 443-454. 10.1111\/j.0141-9838.2004.00727.x.","journal-title":"Parasite Immunol"},{"key":"360_CR27","first-page":"397","volume":"14","author":"N Katz","year":"1972","unstructured":"Katz N, Chaves A, Pellegrino J: A simple device for quantitative stool thick smear technique in schistosomiasis mansoni. Revista do Instituto de Medicina Tropical de Sao Paulo. 1972, 14: 397-400.","journal-title":"Revista do Instituto de Medicina Tropical de Sao Paulo"},{"key":"360_CR28","first-page":"101","volume":"76","author":"KE Mott","year":"1983","unstructured":"Mott KE: A reusable polyamide filter for diagnisis of S. haematobium infection by urine filtration. Bulletin de la Societe de Pathologie Exotique. 1983, 76: 101-104.","journal-title":"Bulletin de la Societe de Pathologie Exotique"},{"key":"360_CR29","doi-asserted-by":"publisher","first-page":"1108","DOI":"10.1086\/432553","volume":"192","author":"F Mutapi","year":"2005","unstructured":"Mutapi F, Burchmore R, Foucher A, Harcus Y, Nicoll G, Midzi N, Turner CM, Maizels R: Praziquantel treatment of people exposed to Schistosoma haematobium enhances serological recognition of defined parasite antigens. Journal of Infectious Diseases. 2005, 192: 1108-1118. 10.1086\/432553.","journal-title":"Journal of Infectious Diseases"},{"key":"360_CR30","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/S0166-6851(02)00098-1","volume":"122","author":"C Fernandez","year":"2002","unstructured":"Fernandez C, Gregory WF, Loke P, Maizels RM: Full-length-enriched cDNA libraries from Echinococcus granulosus contain separate populations of oligo-capped and trans-spliced transcripts and a high level of predicted signal peptide sequences. Mol Biochem Parasitol. 2002, 122: 171-180. 10.1016\/S0166-6851(02)00098-1.","journal-title":"Mol Biochem Parasitol"},{"key":"360_CR31","volume-title":"Molecular Clonning: a laboratory manual","author":"J Sambrook","year":"2001","unstructured":"Sambrook J, Russell DW: Molecular Clonning: a laboratory manual. 2001, 3: 3rd","edition":"3rd"},{"key":"360_CR32","volume-title":"Biostatistical Analysis","author":"JH Zar","year":"1998","unstructured":"Zar JH: Biostatistical Analysis. 1998, , Prentice Hall, 4th","edition":"4th"},{"key":"360_CR33","unstructured":"[\n                    http:\/\/www.expasy.org\/\n                    \n                  ]"},{"key":"360_CR34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/protein\/10.1.1","volume":"10","author":"H Nielsen","year":"1997","unstructured":"Nielsen H, Engelbrecht J, Brunak S, von Heijne G: Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Eng. 1997, 10: 1-6. 10.1093\/protein\/10.1.1.","journal-title":"Protein Eng"},{"key":"360_CR35","first-page":"166","volume":"374","author":"K Hofmann","year":"1993","unstructured":"Hofmann K, Stoffel W: TMbase - A database of membrane spanning proteins segments. Biol Chem. 1993, 374: 166-","journal-title":"Biol Chem"},{"key":"360_CR36","unstructured":"http:\/\/www.ch.embnet.org\/software\/TMPRED_form.html: . [\n                    http:\/\/www.ch.embnet.org\/software\/TMPRED_form.html\n                    \n                  ]"},{"key":"360_CR37","volume-title":"Guidelines for the evaluation of soil-transmitted helminthiasis and schistosomiasis at community level.","author":"A Montresor","year":"1998","unstructured":"Montresor A, Crompton DWT, Bundy DAP, Hall A, Savioli L: Guidelines for the evaluation of soil-transmitted helminthiasis and schistosomiasis at community level. 1998, Geneva, World health Organisation"},{"key":"360_CR38","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/S0001-706X(03)00195-5","volume":"88","author":"M Al-Sherbiny","year":"2003","unstructured":"Al-Sherbiny M, Osman A, Barakat R, El Morshedy H, Bergquist R, Olds R: In vitro cellular and humoral responses to Schistosoma mansoni vaccine candidate antigens. Acta Trop. 2003, 88: 117-130. 10.1016\/S0001-706X(03)00195-5.","journal-title":"Acta Trop"},{"key":"360_CR39","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1517\/14712598.3.8.1271","volume":"3","author":"P Hagan","year":"2003","unstructured":"Hagan P, Sharaf O: Schistosomiasis vaccines. Expert Opin Biol Ther. 2003, 3: 1271-1278. 10.1517\/14712598.3.8.1271.","journal-title":"Expert Opin Biol Ther"},{"key":"360_CR40","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1016\/S1471-4922(01)02118-3","volume":"17","author":"F Mutapi","year":"2001","unstructured":"Mutapi F: Heterogeneities in anti-schistosome humoral responses following chemotherapy. Trends in Parasitology. 2001, 17: 518-524. 10.1016\/S1471-4922(01)02118-3.","journal-title":"Trends in Parasitology"},{"key":"360_CR41","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1017\/S0950268800058453","volume":"115","author":"MS Chan","year":"1995","unstructured":"Chan MS, Guyatt HL, Bundy DAP, Booth M, Fulford AJC, Medley GF: The development of an age structured model for schistosomiasis transmission dynamics and control and its validation for Schistosoma mansoni. Epidemiology and Infection. 1995, 115: 325-344.","journal-title":"Epidemiology and Infection"},{"key":"360_CR42","doi-asserted-by":"publisher","first-page":"1225","DOI":"10.1038\/15169","volume":"5","author":"MEJ Woolhouse","year":"1999","unstructured":"Woolhouse MEJ, Hagan P: Seeking the ghost of worms past. Nature Medicine. 1999, 5: 1225-1227. 10.1038\/15169.","journal-title":"Nature Medicine"},{"key":"360_CR43","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1017\/S0031182099005156","volume":"120 ( Pt 1)","author":"ME Woolhouse","year":"2000","unstructured":"Woolhouse ME, Mutapi F, Ndhlovu PD, Chandiwana SK, Hagan P: Exposure, infection and immune responses to Schistosoma haematobium in young children. Parasitology. 2000, 120 ( Pt 1): 37-44. 10.1017\/S0031182099005156.","journal-title":"Parasitology"},{"key":"360_CR44","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1111\/j.1365-3024.1995.tb00897.x","volume":"17","author":"RJ Quinnell","year":"1995","unstructured":"Quinnell RJ, Woolhouse MEJ, Walsh EA, Pritchard DJ: Immunoepidemiology of human necatorisis: correlations between antibody responses and parasite burdens. Parasite Immunology. 1995, 17: 313-318.","journal-title":"Parasite Immunology"},{"key":"360_CR45","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1016\/0035-9203(73)90079-5","volume":"67","author":"FS McCullough","year":"1973","unstructured":"McCullough FS, Bradley DJ: Egg output stability and the epidemiology of Schistosoma haematobium. I. Variation and stability in Schistosoma haematobium egg counts. Trans R Soc Trop Med Hyg. 1973, 67: 475-490. 10.1016\/0035-9203(73)90079-5.","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"360_CR46","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/0035-9203(84)90282-7","volume":"78","author":"PH Goll","year":"1984","unstructured":"Goll PH, Wilkins HA, Marshall TF: Dynamics of schistosoma haematobium infection in a Gambian community. II. The effect on transmission of the control of Bulinus senegalensis by the use of niclosamide. Trans R Soc Trop Med Hyg. 1984, 78: 222-226. 10.1016\/0035-9203(84)90282-7.","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"360_CR47","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1016\/0035-9203(73)90080-1","volume":"67","author":"DJ Bradley","year":"1973","unstructured":"Bradley DJ, McCullough FS: Egg output stability and the epidemiology of Schistosoma haematobium. II. An analysis of the epidemiology of endemic S. haematobium. Trans R Soc Trop Med Hyg. 1973, 67: 491-500. 10.1016\/0035-9203(73)90080-1.","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"360_CR48","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1017\/S0031182000060364","volume":"102","author":"SK Chandiwana","year":"1991","unstructured":"Chandiwana SK, Woolhouse MEJ, Bradley M: Factors affecting the intensity of reinfection with Schistosoma haematobium following treatment with praziquantel. Parasitology. 1991, 102: 73-83.","journal-title":"Parasitology"}],"container-title":["BMC Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2334-6-96\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2334-6-96.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2334-6-96","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2334-6-96.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,22]],"date-time":"2019-01-22T03:16:12Z","timestamp":1548126972000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/1471-2334-6-96"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,6,9]]},"references-count":48,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["360"],"URL":"https:\/\/doi.org\/10.1186\/1471-2334-6-96","relation":{},"ISSN":["1471-2334"],"issn-type":[{"value":"1471-2334","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,6,9]]},"article-number":"96"}}