{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T03:49:38Z","timestamp":1780631378653,"version":"3.54.1"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2009,5,16]],"date-time":"2009-05-16T00:00:00Z","timestamp":1242432000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"published-print":{"date-parts":[[2009,12]]},"DOI":"10.1186\/1471-2334-9-65","type":"journal-article","created":{"date-parts":[[2009,5,16]],"date-time":"2009-05-16T15:37:25Z","timestamp":1242488245000},"source":"Crossref","is-referenced-by-count":11,"title":["Effectiveness and economic analysis of the whole cell\/recombinant B subunit (WC\/rbs) inactivated oral cholera vaccine in the prevention of traveller's diarrhoea"],"prefix":"10.1186","volume":"9","author":[{"given":"Rosa","family":"L\u00f3pez-Gigosos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Garcia-Fortea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria J","family":"Calvo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilia","family":"Reina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa","family":"Diez-Diaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Plaza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2009,5,16]]},"reference":[{"key":"830_CR1","unstructured":"[\n                    http:\/\/wwwn.cdc.gov\/travel\/yellowBookCh4-Diarrhea.aspx\n                    \n                  ]"},{"issue":"2","key":"830_CR2","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1056\/NEJMoa051331","volume":"354","author":"DO Freedman","year":"2006","unstructured":"Freedman DO, Weld LH, Kozarsky PE, Fisk T, Robins R, Von Sonnenburg F, Keystone JS, Pandey P, Cetron MS: Spectrum of disease and relation to place of exposure among ill returned travelers. New Engl J Med. 2006, 354 (2): 119-130. 10.1056\/NEJMoa051331.","journal-title":"New Engl J Med"},{"key":"830_CR3","volume-title":"Enfermedades Infecciosas Importadas por Viajeros Intercontinentales Espa\u00f1oles. Experiencia de Una D\u00e9cada en Una Unidad de Medicina Tropical","author":"JL Portero","year":"2000","unstructured":"Portero JL: Enfermedades Infecciosas Importadas por Viajeros Intercontinentales Espa\u00f1oles. Experiencia de Una D\u00e9cada en Una Unidad de Medicina Tropical. 2000"},{"key":"830_CR4","first-page":"112","volume-title":"Ericsson CD. Travelers' diarrhea. Hamilton edition","author":"R Steffen","year":"2003","unstructured":"Steffen R, Sack RB: Epidemiology. Ericsson CD. Travelers' diarrhea. Hamilton edition. Edited by: DuPont HL, Steffen R. 2003, Ont.: BC Decker, 112-123."},{"issue":"2","key":"830_CR5","doi-asserted-by":"publisher","first-page":"102","DOI":"10.2310\/7060.2005.12207","volume":"12","author":"R Steffen","year":"2005","unstructured":"Steffen R, Castelli F, Dieter Nothdurft H, Rombo L, Zuckerman JN: Vaccination against enterotoxigenic Escherichia coli, a cause of travelers' diarrhea. J Travel Med. 2005, 12 (2): 102-107.","journal-title":"J Travel Med"},{"issue":"SUPPL 1","key":"830_CR6","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1159\/000089785","volume":"73","author":"J Gasc\u00f3n","year":"2006","unstructured":"Gasc\u00f3n J: Epidemiology, etiology and pathophysiology of traveler's diarrhea. Digestion. 2006, 73 (SUPPL 1): 102-108.","journal-title":"Digestion"},{"issue":"5","key":"830_CR7","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1093\/clind\/16.5.616","volume":"16","author":"CD Ericsson","year":"1993","unstructured":"Ericsson CD, DuPont HL: Travelers' diarrhea: Approaches to prevention and treatment. Clin Infect Dis. 1993, 16 (5): 616-626.","journal-title":"Clin Infect Dis"},{"issue":"15","key":"830_CR8","doi-asserted-by":"publisher","first-page":"2732","DOI":"10.1016\/j.vaccine.2005.10.014","volume":"24","author":"MP Girard","year":"2006","unstructured":"Girard MP, Steele D, Chaignat C, Kieny MP: A review of vaccine research and development: Human enteric infections. Vaccine. 2006, 24 (15): 2732-2750. 10.1016\/j.vaccine.2005.10.014.","journal-title":"Vaccine"},{"key":"830_CR9","first-page":"223","volume":"63","author":"DA Sack","year":"2005","unstructured":"Sack DA, Sack RB, Nair GB, Siddique AK: Cholera. Lancet. 2005, 63: 223-233.","journal-title":"Lancet"},{"issue":"16","key":"830_CR10","first-page":"117","volume":"76","author":"Who","year":"2001","unstructured":"Who: Cholera vaccines. Week Epidem Rec. 2001, 76 (16): 117-125.","journal-title":"Week Epidem Rec"},{"issue":"8","key":"830_CR11","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1016\/S1473-3099(07)70138-X","volume":"7","author":"JN Zuckerman","year":"2007","unstructured":"Zuckerman JN, Rombo L, Fisch A: The true burden and risk of cholera: implications for prevention and control. Lancet Infect Dis. 2007, 7 (8): 521-530. 10.1016\/S1473-3099(07)70138-X.","journal-title":"Lancet Infect Dis"},{"issue":"4","key":"830_CR12","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1111\/j.1708-8305.2008.00210.x","volume":"15","author":"A Tarantola","year":"2008","unstructured":"Tarantola A, Vaucel J, Laviolle C, Quilici M, Thiolet J, Fournier J: A cluster of Vibrio cholerae O1 infections in French travelers to Rajasthan (India), May 2006. J Travel Med. 2008, 15 (4): 273-277. 10.1111\/j.1708-8305.2008.00210.x.","journal-title":"J Travel Med"},{"issue":"5","key":"830_CR13","first-page":"456","volume":"91","author":"B Ivanoff","year":"1998","unstructured":"Ivanoff B: Which vaccines for traveller's diarrheas?. B Soc Pat Ex. 1998, 91 (5): 456-460.","journal-title":"B Soc Pat Ex"},{"key":"830_CR14","unstructured":"Ministerio de Sanidad y Consumo: Informe sobre atenci\u00f3n a los ciudadanos durante 2006, 2005, 2008 (May 14)."},{"issue":"6","key":"830_CR15","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/S1473-3099(06)70494-7","volume":"6","author":"DR Hill","year":"2006","unstructured":"Hill DR, Ford L, Lalloo DG: Oral cholera vaccines: use in clinical practice. Lancet Infect Dis. 2006, 6 (6): 361-373. 10.1016\/S1473-3099(06)70494-7.","journal-title":"Lancet Infect Dis"},{"key":"830_CR16","volume-title":"Edited by Anonymous","author":"SBL Vaccines. Dukoral\u00ae","year":"2005","unstructured":"SBL Vaccines. Dukoral\u00ae: Product monograph. Edited by Anonymous. 2005"},{"issue":"8499","key":"830_CR17","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1016\/S0140-6736(86)91944-6","volume":"2","author":"JD Clemens","year":"1986","unstructured":"Clemens JD, Harris JR, Khan MR: Field trial of oral cholera vaccines in Bangladesh. Lancet. 1986, 2 (8499): 124-127. 10.1016\/S0140-6736(86)91944-6.","journal-title":"Lancet"},{"issue":"2","key":"830_CR18","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1093\/infdis\/158.2.372","volume":"158","author":"JD Clemens","year":"1988","unstructured":"Clemens JD, Sack DA, Harris JR, Chakraborty J, Neogy PK, Stanton B, Huda N, Khan MU, Kay BA, Khan MR, Ansaruzzaman M, Yunus M, Rao MR, Svennerholm A, Holmgren J: Cross-protection by B subunit-whole cell cholera vaccine against diarrhea associated with heat-labile toxin-producing enterotoxigenic Escherichia coli: Results of a large-scale field trial. J Infect Dis. 1988, 158 (2): 372-377.","journal-title":"J Infect Dis"},{"issue":"8778","key":"830_CR19","doi-asserted-by":"publisher","first-page":"1285","DOI":"10.1016\/0140-6736(91)92590-X","volume":"338","author":"H Peltola","year":"1991","unstructured":"Peltola H, Siitonen A, Kyronseppa H, Simula I, Mattila L, Oksanen P, Kataja MJ, Cadoz M: Prevention of travellers' diarrhoea by oral B-subunit\/whole-cell cholera vaccine. Lancet. 1991, 338 (8778): 1285-1289. 10.1016\/0140-6736(91)92590-X.","journal-title":"Lancet"},{"issue":"1","key":"830_CR20","doi-asserted-by":"publisher","first-page":"159","DOI":"10.2307\/2529310","volume":"33","author":"JR Landis","year":"1977","unstructured":"Landis JR, Koch GG: The measurement of observer agreement for categorical data. Biometrics. 1977, 33 (1): 159-174. 10.2307\/2529310.","journal-title":"Biometrics"},{"key":"830_CR21","volume-title":"Estimates of Unit Costs for Patient Services for Spain. Choosing Interventions that are Cost Effective (WHO-CHOICE)","author":"World Health Organization","year":"2007","unstructured":"World Health Organization: Estimates of Unit Costs for Patient Services for Spain. Choosing Interventions that are Cost Effective (WHO-CHOICE). 2007, WHO"},{"key":"830_CR22","volume-title":"Environmental health risks: Treatment of diarrhoea. In: International Travel and Health 2008. Geneva: 2008: 13\u201314","author":"World Health Organization","year":"2008","unstructured":"World Health Organization: Environmental health risks: Treatment of diarrhoea. In: International Travel and Health 2008. Geneva: 2008: 13\u201314. 2008, WHO"},{"issue":"6","key":"830_CR23","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1016\/j.tmaid.2007.06.001","volume":"5","author":"R L\u00f3pez-Gigosos","year":"2007","unstructured":"L\u00f3pez-Gigosos R, Garci\u00eda-Fortea P, Reina-Do\u00f1a E, Plaza-Marti\u00edn E: Effectiveness in prevention of travellers' diarrhoea by an oral cholera vaccine WC\/rBS. Travel Med Infect Dis. 2007, 5 (6): 380-384. 10.1016\/j.tmaid.2007.06.001.","journal-title":"Travel Med Infect Dis"},{"issue":"2","key":"830_CR24","first-page":"26","volume":"3","author":"E Hassan","year":"2006","unstructured":"Hassan E: Recall Bias can be a Threat to Retrospective and Prospective Research Designs. Internet J Epidemiol. 2006, 3 (2): 26-","journal-title":"Internet J Epidemiol"},{"issue":"5\u20136","key":"830_CR25","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1007\/s10354-007-0390-1","volume":"157","author":"H Kollaritsch","year":"2007","unstructured":"Kollaritsch H, Wiedermann U: Examples for vaccines against diarrheal diseases \u2013 Rotavirus and traveller's diarrhea. Wien Med Wochenschr. 2007, 157 (5\u20136): 102-106. 10.1007\/s10354-007-0390-1.","journal-title":"Wien Med Wochenschr"},{"issue":"3","key":"830_CR26","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1007\/s00508-006-0671-5","volume":"118","author":"U Wiedermann","year":"2006","unstructured":"Wiedermann U, Kollaritsch H: Vaccines against traveler's diarrhoea and rotavirus disease \u2013 A review. Wien Klin Wochenschr. 2006, 118 (3): 2-8. 10.1007\/s00508-006-0671-5.","journal-title":"Wien Klin Wochenschr"},{"issue":"65","key":"830_CR27","first-page":"1240","volume":"2","author":"P Landry","year":"2006","unstructured":"Landry P: Diarrhoea and vaccines: Current developments. Rev Med Suisse. 2006, 2 (65): 1240-1244.","journal-title":"Rev Med Suisse"},{"issue":"18","key":"830_CR28","doi-asserted-by":"publisher","first-page":"3865","DOI":"10.1016\/j.vaccine.2006.03.039","volume":"24","author":"MM Levine","year":"2006","unstructured":"Levine MM: Enteric infections and the vaccines to counter them: Future directions. Vaccine. 2006, 24 (18): 3865-3873. 10.1016\/j.vaccine.2006.03.039.","journal-title":"Vaccine"},{"issue":"4 SPEC","key":"830_CR29","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1016\/j.coi.2005.06.007","volume":"17","author":"J S\u00e1nchez","year":"2005","unstructured":"S\u00e1nchez J, Holmgren J: Virulence factors, pathogenesis and vaccine protection in cholera and ETEC diarrhea. Curr Opin Immunol. 2005, 17 (4 SPEC): 388-398. 10.1016\/j.coi.2005.06.007.","journal-title":"Curr Opin Immunol"},{"issue":"1","key":"830_CR30","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1111\/j.1708-8305.2008.00270.x","volume":"16","author":"J Lundkvist","year":"2009","unstructured":"Lundkvist J, Steffen R, J\u00f6nsson B: Cost-benefit of WC\/rBS oral cholera vaccine for vaccination against ETEC-caused travelers' diarrhea. J Travel Med. 2009, 16 (1): 28-34. 10.1111\/j.1708-8305.2008.00270.x.","journal-title":"J Travel Med"},{"issue":"5","key":"830_CR31","doi-asserted-by":"publisher","first-page":"382","DOI":"10.2165\/00019053-199609050-00002","volume":"9","author":"MA Thomson","year":"1996","unstructured":"Thomson MA, Booth IW: Treatment of Traveller's Diarrhoea Economic Aspects. Pharmacoeconomics. 1996, 9 (5): 382-391. 10.2165\/00019053-199609050-00002.","journal-title":"Pharmacoeconomics"},{"issue":"6","key":"830_CR32","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1016\/j.tmaid.2006.05.003","volume":"6","author":"T Weinke","year":"2008","unstructured":"Weinke T, Liebold I, Burchard GD, Fr\u00fchwein N, Grobusch MP, Hatz C, Kollaritsch H, Nothdurft HD, Reisinger E, Rieke B, Sch\u00f6nfeld C, Steffen R, Stich A: Prophylactic immunisation against traveller's diarrhoea caused by enterotoxin-forming strains of Escherichia coli and against cholera: Does it make sense and for whom?. Travel Med Infect Dis. 2008, 6 (6): 362-367. 10.1016\/j.tmaid.2006.05.003.","journal-title":"Travel Med Infect Dis"},{"issue":"2","key":"830_CR33","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1093\/oxfordjournals.bmb.a072609","volume":"49","author":"D Reid","year":"1993","unstructured":"Reid D, Cossar JH: Epidemiology of travel. Brit Med Bull. 1993, 49 (2): 257-268.","journal-title":"Brit Med Bull"},{"issue":"2","key":"830_CR34","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1111\/j.1708-8305.2008.00189.x","volume":"15","author":"M Wang","year":"2008","unstructured":"Wang M, Szucs TD, Steffen R: Economic aspects of travelers' diarrhea. J Travel Med. 2008, 15 (2): 110-118. 10.1111\/j.1708-8305.2008.00189.x.","journal-title":"J Travel Med"}],"container-title":["BMC Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2334-9-65\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2334-9-65.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2334-9-65","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2334-9-65.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,22]],"date-time":"2019-01-22T01:49:29Z","timestamp":1548121769000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/1471-2334-9-65"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5,16]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["830"],"URL":"https:\/\/doi.org\/10.1186\/1471-2334-9-65","relation":{},"ISSN":["1471-2334"],"issn-type":[{"value":"1471-2334","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5,16]]},"article-number":"65"}}