{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T21:12:37Z","timestamp":1770412357272,"version":"3.49.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2007,3,12]],"date-time":"2007-03-12T00:00:00Z","timestamp":1173657600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Med Genet"],"published-print":{"date-parts":[[2007,12]]},"DOI":"10.1186\/1471-2350-8-12","type":"journal-article","created":{"date-parts":[[2007,3,13]],"date-time":"2007-03-13T06:30:18Z","timestamp":1173767418000},"source":"Crossref","is-referenced-by-count":16,"title":["Association between CFL1gene polymorphisms and spina bifida risk in a California population"],"prefix":"10.1186","volume":"8","author":[{"given":"Huiping","family":"Zhu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James O Ebot","family":"Enaw","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary M","family":"Shaw","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward J","family":"Lammer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard H","family":"Finnell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2007,3,12]]},"reference":[{"issue":"3","key":"206_CR1","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/j.ntt.2004.12.007","volume":"27","author":"ER Detrait","year":"2005","unstructured":"Detrait ER, George TM, Etchevers HC, Gilbert JR, Vekemans M, Speer MC: Human neural tube defects: developmental biology, epidemiology, and genetics. Neurotoxicol Teratol. 2005, 27 (3): 515-524. 10.1016\/j.ntt.2004.12.007.","journal-title":"Neurotoxicol Teratol"},{"issue":"9","key":"206_CR2","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1038\/nrn1986","volume":"7","author":"HJ Blom","year":"2006","unstructured":"Blom HJ, Shaw GM, den Heijer M, Finnell RH: Neural tube defects and folate: case far from closed. Nat Rev Neurosci. 2006, 7 (9): 724-731. 10.1038\/nrn1986.","journal-title":"Nat Rev Neurosci"},{"issue":"20","key":"206_CR3","doi-asserted-by":"publisher","first-page":"1485","DOI":"10.1056\/NEJM199911113412001","volume":"341","author":"RJ Berry","year":"1999","unstructured":"Berry RJ, Li Z, Erickson JD, Li S, Moore CA, Wang H, Mulinare J, Zhao P, Wong LY, Gindler J, Hong SX, Correa A: Prevention of neural-tube defects with folic acid in China. China-U.S. Collaborative Project for Neural Tube Defect Prevention. N Engl J Med. 1999, 341 (20): 1485-1490. 10.1056\/NEJM199911113412001.","journal-title":"N Engl J Med"},{"issue":"26","key":"206_CR4","doi-asserted-by":"publisher","first-page":"1832","DOI":"10.1056\/NEJM199212243272602","volume":"327","author":"AE Czeizel","year":"1992","unstructured":"Czeizel AE, Dudas I: Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J Med. 1992, 327 (26): 1832-1835.","journal-title":"N Engl J Med"},{"issue":"8760","key":"206_CR5","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/0140-6736(91)90133-A","volume":"338","author":"MRC","year":"1991","unstructured":"MRC: Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. MRC Vitamin Study Research Group. Lancet. 1991, 338 (8760): 131-137. 10.1016\/0140-6736(91)90133-A.","journal-title":"Lancet"},{"issue":"1","key":"206_CR6","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1006\/mgme.2000.2991","volume":"70","author":"R Barber","year":"2000","unstructured":"Barber R, Shalat S, Hendricks K, Joggerst B, Larsen R, Suarez L, Finnell R: Investigation of Folate Pathway Gene Polymorphisms and the Incidence of Neural Tube Defects in a Texas Hispanic Population. Molecular Genetics and Metabolism. 2000, 70 (1): 45-52. 10.1006\/mgme.2000.2991.","journal-title":"Molecular Genetics and Metabolism"},{"issue":"9","key":"206_CR7","doi-asserted-by":"publisher","first-page":"862","DOI":"10.1093\/oxfordjournals.aje.a010290","volume":"151","author":"LD Botto","year":"2000","unstructured":"Botto LD, Yang Q: 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review. American Journal Of Epidemiology. 2000, 151 (9): 862-877.","journal-title":"American Journal Of Epidemiology"},{"issue":"3","key":"206_CR8","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/S1096-7192(03)00008-8","volume":"78","author":"H Zhu","year":"2003","unstructured":"Zhu H, Wicker NJ, Shaw GM, Lammer EJ, Hendricks K, Suarez L, Canfield M, Finnell RH: Homocysteine remethylation enzyme polymorphisms and increased risks for neural tube defects. Molecular Genetics and Metabolism. 2003, 78 (3): 216-221. 10.1016\/S1096-7192(03)00008-8.","journal-title":"Molecular Genetics and Metabolism"},{"issue":"1","key":"206_CR9","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1093\/oxfordjournals.aje.a009555","volume":"148","author":"GM Shaw","year":"1998","unstructured":"Shaw GM, Rozen R, Finnell RH, Wasserman CR, Lammer EJ: Maternal vitamin use, genetic variation of infant methylenetetrahydrofolate reductase, and risk for spina bifida. American Journal Of Epidemiology. 1998, 148 (1): 30-37.","journal-title":"American Journal Of Epidemiology"},{"issue":"5","key":"206_CR10","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1002\/(SICI)1096-9926(199911)60:5<292::AID-TERA10>3.0.CO;2-6","volume":"60","author":"MJ Harris","year":"1999","unstructured":"Harris MJ, Juriloff DM: Mini-review: toward understanding mechanisms of genetic neural tube defects in mice. Teratology. 1999, 60 (5): 292-305. 10.1002\/(SICI)1096-9926(199911)60:5<292::AID-TERA10>3.0.CO;2-6.","journal-title":"Teratology"},{"issue":"1","key":"206_CR11","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.ydbio.2004.11.010","volume":"278","author":"CB Gurniak","year":"2005","unstructured":"Gurniak CB, Perlas E, Witke W: The actin depolymerizing factor n-cofilin is essential for neural tube morphogenesis and neural crest cell migration. Dev Biol. 2005, 278 (1): 231-241. 10.1016\/j.ydbio.2004.11.010.","journal-title":"Dev Biol"},{"key":"206_CR12","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1111\/j.1469-1809.1996.tb00423.x","volume":"60 ( Pt 3)","author":"GT Gillett","year":"1996","unstructured":"Gillett GT, Fox MF, Rowe PS, Casimir CM, Povey S: Mapping of human non-muscle type cofilin (CFL1) to chromosome 11q13 and muscle-type cofilin (CFL2) to chromosome 14. Ann Hum Genet. 1996, 60 ( Pt 3): 201-211.","journal-title":"Ann Hum Genet"},{"issue":"4","key":"206_CR13","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1111\/j.1365-3016.1991.tb00728.x","volume":"5","author":"LA Croen","year":"1991","unstructured":"Croen LA, Shaw GM, Jensvold NG, Harris JA: Birth defects monitoring in California: a resource for epidemiological research. Paediatr Perinat Epidemiol. 1991, 5 (4): 423-427.","journal-title":"Paediatr Perinat Epidemiol"},{"issue":"1","key":"206_CR14","first-page":"1","volume":"42","author":"J Schulman","year":"1993","unstructured":"Schulman J, Edmonds LD, McClearn AB, Jensvold N, Shaw GM: Surveillance for and comparison of birth defect prevalences in two geographic areas--United States, 1983-88. MMWR CDC Surveill Summ. 1993, 42 (1): 1-7.","journal-title":"MMWR CDC Surveill Summ"},{"key":"206_CR15","first-page":"365","volume":"132","author":"S Rozen","year":"2000","unstructured":"Rozen S, Skaletsky H: Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol. 2000, 132: 365-386.","journal-title":"Methods Mol Biol"},{"issue":"5576","key":"206_CR16","doi-asserted-by":"publisher","first-page":"2225","DOI":"10.1126\/science.1069424","volume":"296","author":"SB Gabriel","year":"2002","unstructured":"Gabriel SB, Schaffner SF, Nguyen H, Moore JM, Roy J, Blumenstiel B, Higgins J, DeFelice M, Lochner A, Faggart M, Liu-Cordero SN, Rotimi C, Adeyemo A, Cooper R, Ward R, Lander ES, Daly MJ, Altshuler D: The structure of haplotype blocks in the human genome. Science. 2002, 296 (5576): 2225-2229. 10.1126\/science.1069424.","journal-title":"Science"},{"key":"206_CR17","unstructured":"Lowry R: VassarStats (http:\/\/faculty.vassar.edu\/lowry\/VassarStats.html)."},{"issue":"Web Server issu","key":"206_CR18","doi-asserted-by":"publisher","first-page":"W635","DOI":"10.1093\/nar\/gkl236","volume":"34","author":"HY Yuan","year":"2006","unstructured":"Yuan HY, Chiou JJ, Tseng WH, Liu CH, Liu CK, Lin YJ, Wang HH, Yao A, Chen YT, Hsu CN: FASTSNP: an always up-to-date and extendable service for SNP function analysis and prioritization. Nucleic Acids Res. 2006, 34 (Web Server issue): W635-41. 10.1093\/nar\/gkl236.","journal-title":"Nucleic Acids Res"},{"issue":"22","key":"206_CR19","doi-asserted-by":"publisher","first-page":"5307","DOI":"10.1021\/bi00317a032","volume":"23","author":"E Nishida","year":"1984","unstructured":"Nishida E, Maekawa S, Sakai H: Cofilin, a protein in porcine brain that binds to actin filaments and inhibits their interactions with myosin and tropomyosin. Biochemistry. 1984, 23 (22): 5307-5313. 10.1021\/bi00317a032.","journal-title":"Biochemistry"},{"issue":"4","key":"206_CR20","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1093\/oxfordjournals.jbchem.a122919","volume":"106","author":"H Abe","year":"1989","unstructured":"Abe H, Ohshima S, Obinata T: A cofilin-like protein is involved in the regulation of actin assembly in developing skeletal muscle. J Biochem (Tokyo). 1989, 106 (4): 696-702.","journal-title":"J Biochem (Tokyo)"},{"issue":"10","key":"206_CR21","doi-asserted-by":"crossref","first-page":"5768","DOI":"10.1016\/S0021-9258(19)39429-3","volume":"265","author":"K Moriyama","year":"1990","unstructured":"Moriyama K, Nishida E, Yonezawa N, Sakai H, Matsumoto S, Iida K, Yahara I: Destrin, a mammalian actin-depolymerizing protein, is closely related to cofilin. Cloning and expression of porcine brain destrin cDNA. J Biol Chem. 1990, 265 (10): 5768-5773.","journal-title":"J Biol Chem"},{"issue":"6753","key":"206_CR22","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1038\/44183","volume":"401","author":"TP Loisel","year":"1999","unstructured":"Loisel TP, Boujemaa R, Pantaloni D, Carlier MF: Reconstitution of actin-based motility of Listeria and Shigella using pure proteins. Nature. 1999, 401 (6753): 613-616. 10.1038\/44183.","journal-title":"Nature"}],"container-title":["BMC Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2350-8-12.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2350-8-12\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2350-8-12","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,11]],"date-time":"2021-08-11T04:25:22Z","timestamp":1628655922000},"score":1,"resource":{"primary":{"URL":"http:\/\/bmcmedgenet.biomedcentral.com\/articles\/10.1186\/1471-2350-8-12"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3,12]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,12]]}},"alternative-id":["206"],"URL":"https:\/\/doi.org\/10.1186\/1471-2350-8-12","relation":{},"ISSN":["1471-2350"],"issn-type":[{"value":"1471-2350","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,3,12]]},"article-number":"12"}}