{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T20:53:20Z","timestamp":1778273600305,"version":"3.51.4"},"reference-count":7,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2006,5,24]],"date-time":"2006-05-24T00:00:00Z","timestamp":1148428800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Nephrol"],"published-print":{"date-parts":[[2006,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Cisplatin is a well-known nephrotoxic antineoplastic drug. Chronic hypokalemic metabolic alkalosis with hypomagnesemia and hypocalciuria is one of the rare complications associated with its use.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Case presentation<\/jats:title>\n            <jats:p>A 42- year-old woman presented with a 20 year-history of hypokalemic metabolic alkalosis with hypomagnesemia and hypocalciuria after cisplatin-based chemotherapy for ovarian cancer. This patient has had chronic muscle aches and fatigue and has had episodic seizure-like activity and periodic paralysis. Only thirteen other patients with similar electrolyte abnormalities have been described in the literature. This case has the longest follow-up.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Cisplatin can cause permanent nephrotoxicity, including Gitelman-like syndrome. This drug should be considered among the possible causes of chronic unexplained electrolyte disorders.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1471-2369-7-10","type":"journal-article","created":{"date-parts":[[2006,5,25]],"date-time":"2006-05-25T06:49:26Z","timestamp":1148539766000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["Gitelman-like syndrome after cisplatin therapy: a case report and literature review"],"prefix":"10.1186","volume":"7","author":[{"given":"Kessarin","family":"Panichpisal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Freddy","family":"Angulo-Pernett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharmila","family":"Selhi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth M","family":"Nugent","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2006,5,24]]},"reference":[{"key":"68_CR1","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1016\/S0270-9295(03)00089-5","volume":"23","author":"I Arany","year":"2003","unstructured":"Arany I, Safirstein RL: Cisplatin nephrotoxicity. 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Am J Nephrol. 1991, 11: 127-130.","journal-title":"Am J Nephrol"},{"key":"68_CR6","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1097\/00000441-200112000-00004","volume":"322","author":"AJ Shaer","year":"2001","unstructured":"Shaer AJ: Inherited Primary Renal Tubular HypokalemicAlkalosis: A Review of Gitelman and Bartter Syndromes. Am J Med Sci. 2001, 322: 316-332. 10.1097\/00000441-200112000-00004.","journal-title":"Am J Med Sci"},{"key":"68_CR7","doi-asserted-by":"publisher","first-page":"73","DOI":"10.5414\/CNP58073","volume":"58","author":"H Mayan","year":"2002","unstructured":"Mayan H, Gurevitz O, Farfei Z: Successful treatment by cyclooxygenase-2 inhibitor of refractory hypokalemia in a patient with Gitelman'syndrome. 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