{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T14:40:14Z","timestamp":1785595214161,"version":"3.56.0"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2011,1,20]],"date-time":"2011-01-20T00:00:00Z","timestamp":1295481600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Neurol"],"published-print":{"date-parts":[[2011,12]]},"DOI":"10.1186\/1471-2377-11-7","type":"journal-article","created":{"date-parts":[[2011,1,20]],"date-time":"2011-01-20T19:19:45Z","timestamp":1295551185000},"source":"Crossref","is-referenced-by-count":29,"title":["A Cost-Consequences analysis of the effect of Pregabalin in the treatment of peripheral Neuropathic Pain in routine medical practice in Primary Care settings"],"prefix":"10.1186","volume":"11","author":[{"given":"Ana","family":"Navarro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda T","family":"Salda\u00f1a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Concepci\u00f3n","family":"P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Torrades","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Rejas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2011,1,20]]},"reference":[{"key":"414_CR1","first-page":"206","volume-title":"Classification of chronic pain syndromes and definitions of pain terms","author":"IASP Task Force in Taxonomy","year":"1994","unstructured":"IASP Task Force in Taxonomy: Pain Terms: A Current List with Definitions and Notes on Usage. Classification of chronic pain syndromes and definitions of pain terms. Edited by: Merksey H, Bogduk N. 1994, Seattle, Washington: IASP Press, 206-213. Second","edition":"Second"},{"key":"414_CR2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0014-2999(01)01302-4","volume":"429","author":"TS Jensen","year":"2001","unstructured":"Jensen TS, Gottrup H, Sindrup SH, et al: The clinical picture of neuropathic pain. Eur J Pharmacol. 2001, 429: 1-11. 10.1016\/S0014-2999(01)01302-4.","journal-title":"Eur J Pharmacol"},{"key":"414_CR3","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1093\/oxfordjournals.bmb.a072498","volume":"47","author":"D Bowsher","year":"1991","unstructured":"Bowsher D: Neurogenic pain syndromes and their management. Br Med Bull. 1991, 47: 644-666.","journal-title":"Br Med Bull"},{"key":"414_CR4","doi-asserted-by":"publisher","first-page":"760","DOI":"10.12968\/hosp.2000.61.11.1459","volume":"6","author":"TE Smith","year":"2000","unstructured":"Smith TE, Chong MS: Neuropathic pain. Hosp Med. 2000, 6: 760-766.","journal-title":"Hosp Med"},{"key":"414_CR5","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1097\/01.ajp.0000210956.31997.89","volume":"23","author":"BH Smith","year":"2007","unstructured":"Smith BH, Torrance N, Bennett MI, Lee AJ: Health and quality of life associated with chronic pain of predominantly neuropathic origin in the community. Clin J Pain. 2007, 23: 143-149. 10.1097\/01.ajp.0000210956.31997.89.","journal-title":"Clin J Pain"},{"key":"414_CR6","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1016\/j.jpainsymman.2005.04.009","volume":"30","author":"M Gore","year":"2005","unstructured":"Gore M, Brandenburg NA, Dukes E, Hoffman DL, Tai KS, Stacey B: Pain severity in diabetic peripheral neuropathy is associated with patient functioning, symptom levels of anxiety and depression, and sleep. J Pain Symptom Manage. 2005, 30: 374-385. 10.1016\/j.jpainsymman.2005.04.009.","journal-title":"J Pain Symptom Manage"},{"key":"414_CR7","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1097\/01.ajp.0000210945.27052.b3","volume":"23","author":"CE Argoff","year":"2007","unstructured":"Argoff CE: The coexistence of neuropathic pain, sleep, and psychiatric disorders: a novel treatment approach. Clin J Pain. 2007, 23: 15-22. 10.1097\/01.ajp.0000210945.27052.b3.","journal-title":"Clin J Pain"},{"key":"414_CR8","doi-asserted-by":"publisher","first-page":"892","DOI":"10.1016\/j.jpain.2006.04.013","volume":"7","author":"M Gore","year":"2006","unstructured":"Gore M, Brandenburg NA, Hoffman DL, Tai KS, Stacey B: Burden of illness in painful diabetic peripheral neuropathy: the patients' perspectives. J Pain. 2006, 7: 892-900. 10.1016\/j.jpain.2006.04.013.","journal-title":"J Pain"},{"key":"414_CR9","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.ejpain.2005.01.014","volume":"10","author":"AM McDermott","year":"2006","unstructured":"McDermott AM, Toelle TR, Rowbotham DJ, Schaefer CP, Dukes EM: The burden of neuropathic pain: results from a cross-sectional survey. Eur J Pain. 2006, 10: 127-135. 10.1016\/j.ejpain.2005.01.014.","journal-title":"Eur J Pain"},{"issue":"5 Suppl","key":"414_CR10","doi-asserted-by":"publisher","first-page":"S12","DOI":"10.1016\/S0885-3924(03)00065-4","volume":"25","author":"N Harden","year":"2003","unstructured":"Harden N, Cohen M: Unmet needs in the management of neuropathic pain. J Pain Symptom Manage. 2003, 25 (5 Suppl): S12-7. 10.1016\/S0885-3924(03)00065-4.","journal-title":"J Pain Symptom Manage"},{"key":"414_CR11","doi-asserted-by":"publisher","first-page":"771","DOI":"10.2165\/00044011-200727110-00004","volume":"27","author":"MJ Rodr\u00edguez","year":"2007","unstructured":"Rodr\u00edguez MJ, Garc\u00eda AJ: A Registry of the Aetiology and Costs of Neuropathic Pain in Pain Clinics: Results of the Registry of aEtiologies and Costs (REC) in Neuropathic Pain Disorders Study. Clin Drug Invest. 2007, 27: 771-782.","journal-title":"Clin Drug Invest"},{"key":"414_CR12","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.jdiacomp.2005.09.007","volume":"20","author":"T Tolle","year":"2006","unstructured":"Tolle T, Xu X, Sadosky AB: Painful diabetic neuropathy: a cross-sectional survey of health state impairment and treatment patterns. J Diabetes Complications. 2006, 20: 26-33. 10.1016\/j.jdiacomp.2005.09.007.","journal-title":"J Diabetes Complications"},{"key":"414_CR13","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1111\/j.1533-2500.2006.00079.x","volume":"6","author":"T Tolle","year":"2006","unstructured":"Tolle T, Dukes E, Sadosky A: Patient burden of trigeminal neuralgia: results from a cross-sectional survey of health state impairment and treatment patterns in six European countries. Pain Pract. 2006, 6: 153-160. 10.1111\/j.1533-2500.2006.00079.x.","journal-title":"Pain Pract"},{"key":"414_CR14","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1093\/ageing\/afj048","volume":"35","author":"R van Seventer","year":"2006","unstructured":"van Seventer R, Sadosky A, Lucero M, Dukes E: A cross-sectional survey of health state impairment and treatment patterns in patients with postherpetic neuralgia. Age Ageing. 2006, 35: 132-137. 10.1093\/ageing\/afj048.","journal-title":"Age Ageing"},{"key":"414_CR15","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.jpain.2003.12.004","volume":"5","author":"A Berger","year":"2004","unstructured":"Berger A, Dukes EM, Oster G: Clinical characteristics and economic costs of patients with painful neuropathic disorders. J Pain. 2004, 5: 143-149. 10.1016\/j.jpain.2003.12.004.","journal-title":"J Pain"},{"issue":"9 Suppl","key":"414_CR16","first-page":"S263","volume":"12","author":"BH McCarberg","year":"2006","unstructured":"McCarberg BH, Billington R: Consequences of neuropathic pain: quality-of-life issues and associated costs. Am J Manag Care. 2006, 12 (9 Suppl): S263-8.","journal-title":"Am J Manag Care"},{"key":"414_CR17","first-page":"12","volume":"3","author":"S Pal","year":"2005","unstructured":"Pal S: Prevalence of chronic pain and migraine. Pharmacist. 2005, 3: 12-15.","journal-title":"Pharmacist"},{"key":"414_CR18","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/j.pain.2005.08.013","volume":"118","author":"NB Finnerup","year":"2005","unstructured":"Finnerup NB, Otto M, McQuay HJ, Jensen TS, Sindrup SH: Algorithm for neuropathic pain treatment: an evidence based proposal. Pain. 2005, 118: 289-305. 10.1016\/j.pain.2005.08.013.","journal-title":"Pain"},{"key":"414_CR19","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.clinthera.2007.01.013","volume":"29","author":"DM Tassone","year":"2007","unstructured":"Tassone DM, Boyce E, Guyer J, Nuzum D: Pregabalin: A novel gamma-aminobutyric acid analogue in the treatment of neuropathic pain, partial-onset seizures, and anxiety disorders. Clin Ther. 2007, 29: 26-48. 10.1016\/j.clinthera.2007.01.013.","journal-title":"Clin Ther"},{"key":"414_CR20","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1097\/ACO.0b013e3282effaa7","volume":"20","author":"I Gilron","year":"2007","unstructured":"Gilron I: Gabapentin and pregabalin for chronic neuropathic and early postsurgical pain: current evidence and future directions. Curr Opin Anaesthesiol. 2007, 20: 456-472. 10.1097\/ACO.0b013e3282effaa7.","journal-title":"Curr Opin Anaesthesiol"},{"key":"414_CR21","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1016\/j.pain.2005.02.032","volume":"115","author":"R Freynhagen","year":"2005","unstructured":"Freynhagen R, Strojek K, Griesing T, Whalen E, Balkenohl M: Efficacy of pregabalin in neuropathic pain evaluated in a 12-week, randomised, double-blind, multicentre, placebo-controlled trial of flexible- and fixed-dose regimens. Pain. 2005, 115: 254-263. 10.1016\/j.pain.2005.02.032.","journal-title":"Pain"},{"key":"414_CR22","doi-asserted-by":"publisher","first-page":"1274","DOI":"10.1212\/01.WNL.0000055433.55136.55","volume":"60","author":"RH Dworkin","year":"2003","unstructured":"Dworkin RH, Corbin AE, Young JP, Sharma U, LaMoreaux L, Bockbrader H, Garofalo EA, Poole RM: Pregabalin for the treatment of postherpetic neuralgia: a randomized, placebo-controlled trial. Neurology. 2003, 60: 1274-1283.","journal-title":"Neurology"},{"key":"414_CR23","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.pain.2004.01.001","volume":"109","author":"R Sabatowski","year":"2004","unstructured":"Sabatowski R, Galvez R, Cherry DA, Jacquot F, Vincent E, Maisonobe P, Versavel M, 1008-045 Study Group: Pregabalin reduces pain and improves sleep and mood disturbances in patients with post-herpetic neuralgia: results of a randomised, placebo-controlled clinical trial. Pain. 2004, 109: 26-35. 10.1016\/j.pain.2004.01.001.","journal-title":"Pain"},{"key":"414_CR24","volume-title":"Pharmacoepidemiology","author":"PD Stolley","year":"2000","unstructured":"Stolley PD, Laporte J: The Public Health, the University, and Pharmacoepidemiology. Pharmacoepidemiology. Edited by: Strom BL. 2000, John Wiley & Sons, Third","edition":"Third"},{"key":"414_CR25","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1111\/j.1526-4637.2004.04036.x","volume":"5","author":"RM Gallagher","year":"2004","unstructured":"Gallagher RM: Naturalistic study designs in samples with refractory pain: advantages and limitations. Pain Med. 2004, 5: 143-145. 10.1111\/j.1526-4637.2004.04036.x.","journal-title":"Pain Med"},{"key":"414_CR26","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1111\/j.1526-4637.2010.00824.x","volume":"11","author":"A Navarro","year":"2010","unstructured":"Navarro A, Salda\u00f1a MT, P\u00e9rez C, Torrades S, Rejas J: Patient-reported outcomes in subjects with neuropathic pain receiving pregabalin: evidence from medical practice in primary care settings. Pain Med. 2010, 11: 719-731. 10.1111\/j.1526-4637.2010.00824.x.","journal-title":"Pain Med"},{"key":"414_CR27","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1186\/1477-7525-5-66","volume":"5","author":"C Perez","year":"2007","unstructured":"Perez C, Galvez R, Huelbes S, Insausti J, Bouhassira D, Diaz S, Rejas J: Validity and reliability of the Spanish version of the DN4 (Douleur Neuropathique 4 questions) questionnaire for differential diagnosis of pain syndromes associated to a neuropathic or somatic component. Health Qual Life Outcomes. 2007, 5: 66-10.1186\/1477-7525-5-66.","journal-title":"Health Qual Life Outcomes"},{"key":"414_CR28","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/0304-3959(87)91074-8","volume":"30","author":"R Melzack","year":"1987","unstructured":"Melzack R: The short-form McGill Pain Questionnaire. Pain. 1987, 30: 191-197. 10.1016\/0304-3959(87)91074-8.","journal-title":"Pain"},{"key":"414_CR29","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1046\/j.1468-2982.1996.1604231.x","volume":"16","author":"WF Stewart","year":"1996","unstructured":"Stewart WF, Lipton RB, Simon D: Work-related disability: results from the American migraine study. Cephalalgia. 1996, 16: 231-238. 10.1046\/j.1468-2982.1996.1604231.x.","journal-title":"Cephalalgia"},{"key":"414_CR30","doi-asserted-by":"publisher","first-page":"1805","DOI":"10.1185\/030079904X10151","volume":"20","author":"T Vicente-Herrero","year":"2004","unstructured":"Vicente-Herrero T, Burke TA, La\u00ednez MJ: The impact of a worksite migraine intervention program on work productivity, productivity costs, and non-workplace impairment among Spanish postal service employees from an employer perspective. Curr Med Res Opin. 2004, 20: 1805-1814. 10.1185\/030079904X10151.","journal-title":"Curr Med Res Opin"},{"key":"414_CR31","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.ejpain.2005.02.007","volume":"10","author":"MT van Leeuwen","year":"2006","unstructured":"van Leeuwen MT, Blyth FM, March LM, Nicholas MK, Cousins MJ: Chronic pain and reduced work effectiveness: the hidden cost to Australian employers. Eur J Pain. 2006, 10: 161-166. 10.1016\/j.ejpain.2005.02.007.","journal-title":"Eur J Pain"},{"key":"414_CR32","volume-title":"Consejo General de Colegios Oficiales de Farmac\u00e9uticos, Madrid","author":"Cat\u00e1logo de Especialidades Farmac\u00e9uticas 2006","year":"2006","unstructured":"Cat\u00e1logo de Especialidades Farmac\u00e9uticas 2006: Consejo General de Colegios Oficiales de Farmac\u00e9uticos, Madrid. 2006"},{"key":"414_CR33","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.jpain.2005.09.004","volume":"7","author":"MS Cepeda","year":"2006","unstructured":"Cepeda MS, Farrar JT: Economic evaluation of oral treatments for neuropathic pain. J Pain. 2006, 7: 119-128. 10.1016\/j.jpain.2005.09.004.","journal-title":"J Pain"},{"key":"414_CR34","doi-asserted-by":"publisher","first-page":"2585","DOI":"10.1185\/030079907X233151","volume":"23","author":"MJ Rodr\u00edguez","year":"2007","unstructured":"Rodr\u00edguez MJ, D\u00edaz S, Vera-Llonch M, Dukes E, Rejas J: Cost-effectiveness analysis of pregabalin versus gabapentin in the management of neuropathic pain due to diabetic polyneuropathy or post-herpetic neuralgia. Curr Med Res Opin. 2007, 23: 2585-2596.","journal-title":"Curr Med Res Opin"},{"key":"414_CR35","doi-asserted-by":"publisher","first-page":"1922","DOI":"10.1016\/j.clinthera.2006.11.017","volume":"28","author":"JE Tarride","year":"2006","unstructured":"Tarride JE, Gordon A, Vera-Llonch M, et al: Cost-effectiveness of Pregabalin for the Management of Neuropathic Pain Associated with Diabetic Peripheral neuropathy and Postherpetic Neuralgia: A Canadian Perspective. Clin Ther. 2006, 28: 1922-1934. 10.1016\/j.clinthera.2006.11.017.","journal-title":"Clin Ther"},{"key":"414_CR36","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1179\/acb.2008.027","volume":"63","author":"L Annemans","year":"2008","unstructured":"Annemans L, Caekelbergh K, Morlion B, Hans G, De Cock P, Marbaix S: A cost-utility analysis of pregabalin in the management of peripheral neuropathic pain. Acta Clin Belg. 2008, 63: 170-178.","journal-title":"Acta Clin Belg"},{"key":"414_CR37","doi-asserted-by":"publisher","first-page":"1176","DOI":"10.1111\/j.1532-5415.2007.01246.x","volume":"55","author":"AB O'Connor","year":"2007","unstructured":"O'Connor AB, Noyes K, Holloway RG: A cost-effectiveness comparison of desipramine, gabapentin, and pregabalin for treating postherpetic neuralgia. J Am Geriatr Soc. 2007, 55: 1176-1184.","journal-title":"J Am Geriatr Soc"},{"key":"414_CR38","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1016\/j.pain.2004.05.001","volume":"110","author":"J Rosenstock","year":"2004","unstructured":"Rosenstock J, Tuchman M, LaMoreaux L, Sharma U: Pregabalin for the treatment of painful diabetic peripheral neuropathy: a double-blind, placebo-controlled trial. Pain. 2004, 110: 628-638. 10.1016\/j.pain.2004.05.001.","journal-title":"Pain"},{"key":"414_CR39","doi-asserted-by":"publisher","first-page":"2104","DOI":"10.1212\/01.WNL.0000145767.36287.A1","volume":"63","author":"H Lesser","year":"2004","unstructured":"Lesser H, Sharma U, LaMoreaux L, Poole RM: Pregabalin relieves symptoms of painful diabetic neuropathy: a randomized controlled trial. Neurology. 2004, 63: 2104-2110.","journal-title":"Neurology"},{"key":"414_CR40","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/j.jpain.2004.12.007","volume":"6","author":"RW Richter","year":"2005","unstructured":"Richter RW, Portenoy R, Sharma U, Lamoreaux L, Bockbrader H, Knapp LE: Relief of painful diabetic peripheral neuropathy with pregabalin: a randomized, placebo-controlled trial. J Pain. 2005, 6: 253-260. 10.1016\/j.jpain.2004.12.007.","journal-title":"J Pain"},{"key":"414_CR41","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1185\/030079906X80404","volume":"22","author":"R van Seventer","year":"2006","unstructured":"van Seventer R, Feister HA, Young JP, Stoker M, Versavel M, Rigaudy L: Efficacy and tolerability of twice-daily pregabalin for treating pain and related sleep interference in postherpetic neuralgia: a 13-week, randomized trial. Curr Med Res Opin. 2006, 22: 375-384. 10.1185\/030079906X80404.","journal-title":"Curr Med Res Opin"},{"key":"414_CR42","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1503\/cmaj.060146","volume":"175","author":"I Gilron","year":"2006","unstructured":"Gilron I, Watson CP, Cahill CM, Moulin DE: Neuropathic pain: a practical guide for the clinician. CMAJ. 2006, 175: 265-275.","journal-title":"CMAJ"},{"key":"414_CR43","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1016\/j.berh.2005.03.007","volume":"19","author":"N van der Roer","year":"2005","unstructured":"van der Roer N, Goossens ME, Evers SM, van Tulder MW: What is the most cost-effective treatment for patients with low back pain? A systematic review. Best Pract Res Clin Rheumatol. 2005, 19: 671-684. 10.1016\/j.berh.2005.03.007.","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"414_CR44","volume-title":"Pharmacoepidemiology","author":"J Collet","year":"2000","unstructured":"Collet J, Boivin J: Bias and Confounding in Pharmacoepidemiology. Pharmacoepidemiology. Edited by: Strom BL. 2000, John Wiley & Sons, Third","edition":"Third"}],"container-title":["BMC Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2377-11-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2377-11-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2377-11-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,19]],"date-time":"2017-06-19T18:41:26Z","timestamp":1497897686000},"score":1,"resource":{"primary":{"URL":"http:\/\/bmcneurol.biomedcentral.com\/articles\/10.1186\/1471-2377-11-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1,20]]},"references-count":44,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["414"],"URL":"https:\/\/doi.org\/10.1186\/1471-2377-11-7","relation":{},"ISSN":["1471-2377"],"issn-type":[{"value":"1471-2377","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,1,20]]},"article-number":"7"}}