{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T07:11:32Z","timestamp":1781075492565,"version":"3.54.1"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2012,8,21]],"date-time":"2012-08-21T00:00:00Z","timestamp":1345507200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Neurol"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1186\/1471-2377-12-78","type":"journal-article","created":{"date-parts":[[2012,8,21]],"date-time":"2012-08-21T04:15:03Z","timestamp":1345522503000},"source":"Crossref","is-referenced-by-count":18,"title":["Inflammatory-like presentation of CADASIL: a diagnostic challenge"],"prefix":"10.1186","volume":"12","author":[{"given":"Nicolas","family":"Collongues","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Derache","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Blanc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Labauge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00f4me","family":"de Seze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Defer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,8,21]]},"reference":[{"issue":"7","key":"636_CR1","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1016\/S1474-4422(09)70127-9","volume":"8","author":"H Chabriat","year":"2009","unstructured":"Chabriat H, Joutel A, Dichgans M, Tournier-Lasserve E, Bousser MG: Cadasil. Lancet Neurol. 2009, 8 (7): 643-653. 10.1016\/S1474-4422(09)70127-9.","journal-title":"Lancet Neurol"},{"issue":"1","key":"636_CR2","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1136\/jnnp.71.1.97","volume":"71","author":"SA Broadley","year":"2001","unstructured":"Broadley SA, Sawcer SJ, Chataway SJ, Coraddu F, Coles A, Gray J, Roxburgh R, Clayton D, Compston DA: No association between multiple sclerosis and the Notch3 gene responsible for cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). J Neurol Neurosurg Psychiatry. 2001, 71 (1): 97-99. 10.1136\/jnnp.71.1.97.","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"4","key":"636_CR3","doi-asserted-by":"publisher","first-page":"427","DOI":"10.2174\/156652407780831593","volume":"7","author":"R Rampal","year":"2007","unstructured":"Rampal R, Luther KB, Haltiwanger RS: Notch signaling in normal and disease States: possible therapies related to glycosylation. Curr Mol Med. 2007, 7 (4): 427-445. 10.2174\/156652407780831593.","journal-title":"Curr Mol Med"},{"issue":"6","key":"636_CR4","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1177\/1352458511404033","volume":"17","author":"A La Russa","year":"2011","unstructured":"La Russa A, Cittadella R, Andreoli V, Valentino P, Trecroci F, Caracciolo M, Gallo O, Gambardella A, Quattrone A: Leber\u2019s hereditary optic neuropathy associated with a multiple-sclerosis-like picture in a man. Mult Scler. 2011, 17 (6): 763-766. 10.1177\/1352458511404033.","journal-title":"Mult Scler"},{"issue":"9","key":"636_CR5","doi-asserted-by":"publisher","first-page":"1140","DOI":"10.1001\/archneurol.2010.219","volume":"67","author":"A Echaniz-Laguna","year":"2010","unstructured":"Echaniz-Laguna A, Chassagne M, de Seze J, Mohr M, Clerc-Renaud P, Tranchant C, Mousson de Camaret B: POLG1 variations presenting as multiple sclerosis. Arch Neurol. 2010, 67 (9): 1140-1143. 10.1001\/archneurol.2010.219.","journal-title":"Arch Neurol"},{"issue":"8","key":"636_CR6","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1136\/jnnp.2010.223297","volume":"82","author":"P Bentley","year":"2011","unstructured":"Bentley P, Wang T, Malik O, Nicholas R, Ban M, Sawcer S, Sharma P: CADASIL with cord involvement associated with a novel and atypical NOTCH3 mutation. J Neurol Neurosurg Psychiatry. 2011, 82 (8): 855-860. 10.1136\/jnnp.2010.223297.","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"10","key":"636_CR7","doi-asserted-by":"publisher","first-page":"1888","DOI":"10.1007\/s00415-011-6023-z","volume":"258","author":"C Vedeler","year":"2011","unstructured":"Vedeler C, Bindoff L: A family with atypical CADASIL. J Neurol. 2011, 258 (10): 1888-1889. 10.1007\/s00415-011-6023-z.","journal-title":"J Neurol"},{"issue":"1","key":"636_CR8","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1002\/bies.201000093","volume":"33","author":"A Joutel","year":"2011","unstructured":"Joutel A: Pathogenesis of CADASIL: transgenic and knock-out mice to probe function and dysfunction of the mutated gene, Notch3, in the cerebrovasculature. Bioessays. 2011, 33 (1): 73-80. 10.1002\/bies.201000093.","journal-title":"Bioessays"},{"issue":"4","key":"636_CR9","doi-asserted-by":"publisher","first-page":"2634","DOI":"10.4049\/jimmunol.180.4.2634","volume":"180","author":"M Jurynczyk","year":"2008","unstructured":"Jurynczyk M, Jurewicz A, Raine CS, Selmaj K: Notch3 inhibition in myelin-reactive T cells down-regulates protein kinase C theta and attenuates experimental autoimmune encephalomyelitis. J Immunol. 2008, 180 (4): 2634-2640.","journal-title":"J Immunol"},{"issue":"3","key":"636_CR10","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1007\/s00401-006-0116-2","volume":"112","author":"A Ishiko","year":"2006","unstructured":"Ishiko A, Shimizu A, Nagata E, Takahashi K, Tabira T, Suzuki N: Notch3 ectodomain is a major component of granular osmiophilic material (GOM) in CADASIL. Acta Neuropathol. 2006, 112 (3): 333-339. 10.1007\/s00401-006-0116-2.","journal-title":"Acta Neuropathol"}],"container-title":["BMC Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2377-12-78.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2377-12-78\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2377-12-78","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,7,11]],"date-time":"2016-07-11T20:23:25Z","timestamp":1468268605000},"score":1,"resource":{"primary":{"URL":"http:\/\/bmcneurol.biomedcentral.com\/articles\/10.1186\/1471-2377-12-78"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8,21]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["636"],"URL":"https:\/\/doi.org\/10.1186\/1471-2377-12-78","relation":{},"ISSN":["1471-2377"],"issn-type":[{"value":"1471-2377","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,8,21]]},"article-number":"78"}}