{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T14:58:10Z","timestamp":1780757890444,"version":"3.54.1"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2014,5,7]],"date-time":"2014-05-07T00:00:00Z","timestamp":1399420800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Neurol"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1186\/1471-2377-14-100","type":"journal-article","created":{"date-parts":[[2014,5,7]],"date-time":"2014-05-07T11:04:48Z","timestamp":1399460688000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Comparison of diffusion-weighted imaging and contrast-enhanced T1-weighted imaging on a single baseline MRI for demonstrating dissemination in time in multiple sclerosis"],"prefix":"10.1186","volume":"14","author":[{"given":"Chung-Ping","family":"Lo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hung-Wen","family":"Kao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shao-Yuan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi-Ming","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia-Chun","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-Chu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Chen","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dai-Wei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Lin","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,5,7]]},"reference":[{"key":"1022_CR1","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1002\/ana.22366","volume":"69","author":"CH Polman","year":"2011","unstructured":"Polman CH, Reingold SC, Banwell B, Clanet M, Cohen JA, Filippi M, Fujihara K, Havrdova E, Hutchinson M, Kappos L, Lublin FD, Montalban X, O\u2019Connor P, Sandberg-Wollheim M, Thompson AJ, Waubant E, Weinshenker B, Wolinsky JS: Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann Neurol. 2011, 69: 292-302. 10.1002\/ana.22366.","journal-title":"Ann Neurol"},{"key":"1022_CR2","doi-asserted-by":"publisher","first-page":"830","DOI":"10.1136\/jnnp.2005.073247","volume":"77","author":"JK Swanton","year":"2006","unstructured":"Swanton JK, Fernando K, Dalton CM, Miszkiel KA, Thompson AJ, Plant GT, Miller DH: Modification of MRI criteria for multiple sclerosis in patients with clinically isolated syndromes. J Neurol Neurosurg Psychiatry. 2006, 77: 830-833. 10.1136\/jnnp.2005.073247.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"1022_CR3","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1016\/S1474-4422(07)70176-X","volume":"6","author":"JK Swanton","year":"2007","unstructured":"Swanton JK, Rovira A, Tintor\u00e9 M, Altmann DR, Barkhof F, Filippi M, Huerga E, Miszkiel KA, Plant GT, Polman C, Rovaris M, Thompson AJ, Montalban X, Miller DH: MRI criteria for multiple sclerosis in patients presenting with clinically isolated syndromes: a multicentre retrospective study. Lancet Neurol. 2007, 6: 677-686. 10.1016\/S1474-4422(07)70176-X.","journal-title":"Lancet Neurol"},{"key":"1022_CR4","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1001\/archneurol.2009.49","volume":"66","author":"A Rovira","year":"2009","unstructured":"Rovira A, Swanton J, Tintor\u00e9 M, Huerga E, Barkhof F, Filippi M, Frederiksen JL, Langkilde A, Miszkiel K, Polman C, Rovaris M, Sastre-Garriga J, Miller D, Montalban X: A single, early magnetic resonance imaging study in the diagnosis of multiple sclerosis. Arch Neurol. 2009, 66: 587-592.","journal-title":"Arch Neurol"},{"key":"1022_CR5","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1007\/s00330-012-2597-9","volume":"23","author":"HS Thomsen","year":"2013","unstructured":"Thomsen HS, Morcos SK, Alm\u00e9n T, Bellin M-F, Bertolotto M, Bongartz G, Clement O, Leander P, Heinz-Peer G, Reimer P, Stacul F, van der Molen A, Webb JAW: Nephrogenic systemic fibrosis and gadolinium-based contrast media: updated ESUR Contrast Medium Safety Committee guidelines. Eur Radiol. 2013, 23: 307-318. 10.1007\/s00330-012-2597-9.","journal-title":"Eur Radiol"},{"key":"1022_CR6","unstructured":"ACR manual on contrast media: Version 9, 2013 [Internet] Reston, VA: American College of Radiology, ACR Committee on Drugs and Contrast Media; c2013. [cited 2013 March 21]. Available from: \n                    http:\/\/www.acr.org\/~\/media\/ACR\/Documents\/PDF\/QualitySafety\/Resources\/Contrast%20Manual\/2013_Contrast_Media.pdf\n                    \n                  .,"},{"key":"1022_CR7","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1177\/1352458511417828","volume":"18","author":"M G\u00f3mez-Moreno","year":"2012","unstructured":"G\u00f3mez-Moreno M, D\u00edaz-S\u00e1nchez M, Ramos-Gonz\u00e1lez A: Application of the 2010 McDonald criteria for the diagnosis of multiple sclerosis in a Spanish cohort of patients with clinically isolated syndromes. Mult Scler. 2012, 18: 39-44. 10.1177\/1352458511417828.","journal-title":"Mult Scler"},{"key":"1022_CR8","first-page":"1006","volume":"27","author":"C Rosso","year":"2006","unstructured":"Rosso C, Remy P, Creange A, Brugieres P, Cesaro P, Hosseini H: Diffusion-weighted MR imaging characteristics of an acute stroke-like form of multiple sclerosis. AJNR Am J Neuroradiol. 2006, 27: 1006-1008.","journal-title":"AJNR Am J Neuroradiol"},{"key":"1022_CR9","first-page":"869","volume":"21","author":"S Roychowdhury","year":"2000","unstructured":"Roychowdhury S, Maldjian JA, Grossman RI: Multiple sclerosis: comparison of trace apparent diffusion coefficients with MR enhancement pattern of lesions. AJNR Am J Neuroradiol. 2000, 21: 869-874.","journal-title":"AJNR Am J Neuroradiol"},{"key":"1022_CR10","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.3174\/ajnr.A2975","volume":"33","author":"P Eisele","year":"2012","unstructured":"Eisele P, Szabo K, Griebe M, Ro\u00dfmanith C, F\u00f6rster A, Hennerici M, Gass A: Reduced diffusion is a subset of acute MS lesions: a serial multiparametric MRI study. AJNR Am J Neuroradiol. 2012, 33: 1369-1373. 10.3174\/ajnr.A2975.","journal-title":"AJNR Am J Neuroradiol"},{"key":"1022_CR11","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1148\/radiology.217.2.r00nv24331","volume":"217","author":"PW Schaefer","year":"2000","unstructured":"Schaefer PW, Grant PE, Gonzalez RG: Diffusion-weighted MR imaging of the brain1. Radiology. 2000, 217: 331-345. 10.1148\/radiology.217.2.r00nv24331.","journal-title":"Radiology"},{"key":"1022_CR12","doi-asserted-by":"publisher","first-page":"764","DOI":"10.1007\/s00234-002-0806-y","volume":"44","author":"A Castriota-Scanderbeg","year":"2002","unstructured":"Castriota-Scanderbeg A, Sabatini U, Fasano F, Floris R, Fraracci L, Mario MD, Nocentini U, Caltagirone C: Diffusion of water in large demyelinating lesions: a follow-up study. Neuroradiology. 2002, 44: 764-767. 10.1007\/s00234-002-0806-y.","journal-title":"Neuroradiology"},{"key":"1022_CR13","doi-asserted-by":"publisher","first-page":"e7","DOI":"10.1148\/rg.e7","volume":"23","author":"T Stadnik","year":"2003","unstructured":"Stadnik T, Demaerel P, Luypaert R, Chaskis C, Van Rompaey KL, Michotte A, Osteaux MJ: Imaging tutorial: differential diagnosis of bright lesions on diffusion-weighted MR images. Radiographics. 2003, 23: e7-10.1148\/rg.e7.","journal-title":"Radiographics"},{"key":"1022_CR14","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1046\/j.1365-2990.2000.00217.x","volume":"26","author":"P van der Valk","year":"2000","unstructured":"van der Valk P, De Groot CJA: Staging of multiple sclerosis (MS) lesions: pathology of the time frame of MS. Neuropathol Appl Neurobiol. 2000, 26: 2-10. 10.1046\/j.1365-2990.2000.00217.x.","journal-title":"Neuropathol Appl Neurobiol"},{"key":"1022_CR15","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1002\/1531-8249(200006)47:6<707::AID-ANA3>3.0.CO;2-Q","volume":"47","author":"C Lucchinetti","year":"2000","unstructured":"Lucchinetti C, Br\u00fcck W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H: Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination. Ann Neurol. 2000, 47: 707-717. 10.1002\/1531-8249(200006)47:6<707::AID-ANA3>3.0.CO;2-Q.","journal-title":"Ann Neurol"},{"key":"1022_CR16","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1017\/S0317167100014074","volume":"39","author":"H Rigby","year":"2012","unstructured":"Rigby H, Maloney W, Bhan V: Diagnostic considerations in acute MS lesions with restricted diffusion on MRI. Can J Neurol Sci. 2012, 39: 525-526.","journal-title":"Can J Neurol Sci"},{"key":"1022_CR17","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1111\/j.1552-6569.2009.00443.x","volume":"21","author":"KE Balashov","year":"2011","unstructured":"Balashov KE, Aung LL, Dhib-Jalbut S, Keller IA: Acute multiple sclerosis lesion: conversion of restricted diffusion due to vasogenic edema. J Neuroimaging. 2011, 21: 202-204. 10.1111\/j.1552-6569.2009.00443.x.","journal-title":"J Neuroimaging"},{"key":"1022_CR18","doi-asserted-by":"publisher","first-page":"1996","DOI":"10.1016\/j.ejrad.2013.07.026","volume":"82","author":"C Koelblinger","year":"2013","unstructured":"Koelblinger C, Fruehwald-Pallamar J, Kubin K, Wallner-Blazek M, van den Hauwe L, Macedo L, Puchner SB, Thurnher MM: Atypical idiopathic inflammatory demyelinating lesions (IIDL): conventional and diffusion-weighted MR imaging (DWI) findings in 42 cases. Eur J Radiol. 2013, 82: 1996-2004. 10.1016\/j.ejrad.2013.07.026.","journal-title":"Eur J Radiol"},{"key":"1022_CR19","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1016\/j.ejrad.2007.05.002","volume":"65","author":"I Yurtsever","year":"2008","unstructured":"Yurtsever I, Hakyemez B, Taskapilioglu O, Erdogan C, Turan OF, Parlak M: The contribution of diffusion-weighted MR imaging in multiple sclerosis during acute attack. Eur J Radiol. 2008, 65: 421-426. 10.1016\/j.ejrad.2007.05.002.","journal-title":"Eur J Radiol"},{"key":"1022_CR20","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1056\/NEJM199801293380502","volume":"15","author":"BD Trapp","year":"1998","unstructured":"Trapp BD, Peterson J, Ransohoff RM, Rudick R, M\u00f6rk S, B\u00f6 L: Axonal transection in the lesions of multiple sclerosis. N Engl J Med. 1998, 15: 278-285.","journal-title":"N Engl J Med"}],"container-title":["BMC Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2377-14-100.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2377-14-100\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2377-14-100","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2377-14-100.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,23]],"date-time":"2019-01-23T06:44:23Z","timestamp":1548225863000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcneurol.biomedcentral.com\/articles\/10.1186\/1471-2377-14-100"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,7]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["1022"],"URL":"https:\/\/doi.org\/10.1186\/1471-2377-14-100","relation":{},"ISSN":["1471-2377"],"issn-type":[{"value":"1471-2377","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,7]]},"assertion":[{"value":"5 January 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 March 2014","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 May 2014","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"100"}}