{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T05:24:40Z","timestamp":1791869080570,"version":"4.3.4"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2011,1,28]],"date-time":"2011-01-28T00:00:00Z","timestamp":1296172800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Cancer"],"published-print":{"date-parts":[[2011,12]]},"DOI":"10.1186\/1471-2407-11-41","type":"journal-article","created":{"date-parts":[[2011,2,8]],"date-time":"2011-02-08T14:52:05Z","timestamp":1297176725000},"source":"Crossref","is-referenced-by-count":26,"title":["Phase II study evaluating consolidation whole abdominal intensity-modulated radiotherapy (IMRT) in patients with advanced ovarian cancer stage FIGO III - The OVAR-IMRT-02 Study"],"prefix":"10.1186","volume":"11","author":[{"given":"Nathalie","family":"Rochet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meinhard","family":"Kieser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Sterzing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonja","family":"Krause","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja","family":"Lindel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Harms","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael H","family":"Eichbaum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Schneeweiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christof","family":"Sohn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juergen","family":"Debus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2011,1,28]]},"reference":[{"key":"2551_CR1","doi-asserted-by":"publisher","first-page":"1248","DOI":"10.1200\/JCO.20.5.1248","volume":"20","author":"RE Bristow","year":"2002","unstructured":"Bristow RE, Tomacruz RS, Armstrong DK, Trimble EL, Montz FJ: Survival effect of maximal cytoreductive surgery for advanced ovarian carcinoma during the platinum era: a meta-analysis. J Clin Oncol. 2002, 20: 1248-1259. 10.1200\/JCO.20.5.1248.","journal-title":"J Clin Oncol"},{"key":"2551_CR2","doi-asserted-by":"publisher","first-page":"129s","DOI":"10.1200\/JCO.2003.04.003","volume":"21","author":"SA Cannistra","year":"2003","unstructured":"Cannistra SA, Bast RC, Berek JS, Bookman MA, Crum CP, DePriest PD, et al: Progress in the management of gynecologic cancer: consensus summary statement. J Clin Oncol. 2003, 21: 129s-132s. 10.1200\/JCO.2003.04.003.","journal-title":"J Clin Oncol"},{"key":"2551_CR3","doi-asserted-by":"publisher","first-page":"772","DOI":"10.1111\/j.1048-891X.2004.014507.x","volume":"14","author":"HE Lambert","year":"2004","unstructured":"Lambert HE, Gregory WM, Nelstrop AE, Rustin GJ: Long-term survival in 463 women treated with platinum analogs for advanced epithelial carcinoma of the ovary: life expectancy compared to women of an age-matched normal population. Int J Gynecol Cancer. 2004, 14: 772-778. 10.1111\/j.1048-891X.2004.014507.x.","journal-title":"Int J Gynecol Cancer"},{"key":"2551_CR4","doi-asserted-by":"publisher","first-page":"133s","DOI":"10.1200\/JCO.2003.01.066","volume":"21","author":"WP McGuire III","year":"2003","unstructured":"McGuire WP: Current status of taxane and platinum-based chemotherapy in ovarian cancer. J Clin Oncol. 2003, 21: 133s-135s. 10.1200\/JCO.2003.01.066.","journal-title":"J Clin Oncol"},{"key":"2551_CR5","doi-asserted-by":"publisher","first-page":"3194","DOI":"10.1200\/JCO.2003.02.153","volume":"21","author":"RF Ozols","year":"2003","unstructured":"Ozols RF, Bundy BN, Greer BE, Fowler JM, Clarke-Pearson D, Burger RA, et al: Phase III trial of carboplatin and paclitaxel compared with cisplatin and paclitaxel in patients with optimally resected stage III ovarian cancer: a Gynecologic Oncology Group study. J Clin Oncol. 2003, 21: 3194-3200. 10.1200\/JCO.2003.02.153.","journal-title":"J Clin Oncol"},{"key":"2551_CR6","doi-asserted-by":"publisher","first-page":"1219","DOI":"10.1038\/sj.bmt.1704473","volume":"33","author":"ML Donato","year":"2004","unstructured":"Donato ML, Aleman A, Champlin RE, Saliba RM, Wharton JT, Burke TW, et al: Analysis of 96 patients with advanced ovarian carcinoma treated with high-dose chemotherapy and autologous stem cell transplantation. Bone Marrow Transplant. 2004, 33: 1219-1224. 10.1038\/sj.bmt.1704473.","journal-title":"Bone Marrow Transplant"},{"key":"2551_CR7","doi-asserted-by":"publisher","first-page":"1865","DOI":"10.1002\/1097-0142(19940401)73:7<1865::AID-CNCR2820730715>3.0.CO;2-T","volume":"73","author":"P Dufour","year":"1994","unstructured":"Dufour P, Bergerat JP, Barats JC, Giron C, Duclos B, Dellenbach P, et al: Intraperitoneal mitoxantrone as consolidation treatment for patients with ovarian carcinoma in pathologic complete remission. Cancer. 1994, 73: 1865-1869. 10.1002\/1097-0142(19940401)73:7<1865::AID-CNCR2820730715>3.0.CO;2-T.","journal-title":"Cancer"},{"key":"2551_CR8","doi-asserted-by":"publisher","first-page":"2849","DOI":"10.1200\/JCO.2003.11.018","volume":"21","author":"MA Varia","year":"2003","unstructured":"Varia MA, Stehman FB, Bundy BN, Benda JA, Clarke-Pearson DL, Alvarez RD, et al: Intraperitoneal radioactive phosphorus (32P) versus observation after negative second-look laparotomy for stage III ovarian carcinoma: a randomized trial of the Gynecologic Oncology Group. J Clin Oncol. 2003, 21: 2849-2855. 10.1200\/JCO.2003.11.018.","journal-title":"J Clin Oncol"},{"key":"2551_CR9","doi-asserted-by":"publisher","first-page":"2285","DOI":"10.1002\/1097-0142(19850501)55:9+<2285::AID-CNCR2820551436>3.0.CO;2-4","volume":"55","author":"AJ Dembo","year":"1985","unstructured":"Dembo AJ: Abdominopelvic radiotherapy in ovarian cancer. A 10-year experience. Cancer. 1985, 55: 2285-2290. 10.1002\/1097-0142(19850501)55:9+<2285::AID-CNCR2820551436>3.0.CO;2-4.","journal-title":"Cancer"},{"key":"2551_CR10","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1016\/0360-3016(92)90777-F","volume":"22","author":"AJ Dembo","year":"1992","unstructured":"Dembo AJ: Epithelial ovarian cancer: the role of radiotherapy. Int J Radiat Oncol Biol Phys. 1992, 22: 835-845. 10.1016\/0360-3016(92)90777-F.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2551_CR11","first-page":"149","volume":"42","author":"JP Smith","year":"1975","unstructured":"Smith JP, Rutledge FN, Delclos L: Postoperative treatment of early cancer of the ovary: a random trial between postoperative irradiation and chemotherapy. Natl Cancer Inst Monogr. 1975, 42: 149-153.","journal-title":"Natl Cancer Inst Monogr"},{"key":"2551_CR12","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1006\/gyno.1999.5477","volume":"74","author":"KS Kapp","year":"1999","unstructured":"Kapp KS, Kapp DS, Poschauko J, Stucklschweiger GF, Hackl A, Pickel H, et al: The prognostic significance of peritoneal seeding and size of postsurgical residual in patients with stage III epithelial ovarian cancer treated with surgery, chemotherapy, and high-dose radiotherapy. Gynecol Oncol. 1999, 74: 400-407. 10.1006\/gyno.1999.5477.","journal-title":"Gynecol Oncol"},{"key":"2551_CR13","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1023\/A:1008256431090","volume":"8","author":"HE Lambert","year":"1997","unstructured":"Lambert HE, Rustin GJ, Gregory WM, Nelstrop AE: A randomized trial of five versus eight courses of cisplatin or carboplatin in advanced epithelial ovarian carcinoma. A North Thames Ovary Group Study. Ann Oncol. 1997, 8: 327-333. 10.1023\/A:1008256431090.","journal-title":"Ann Oncol"},{"key":"2551_CR14","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1006\/gyno.1999.5541","volume":"75","author":"A MacGibbon","year":"1999","unstructured":"MacGibbon A, Bucci J, MacLeod C, Solomon J, Dalrymple C, Firth I, et al: Whole abdominal radiotherapy following second-look laparotomy for ovarian carcinoma. Gynecol Oncol. 1999, 75: 62-67. 10.1006\/gyno.1999.5541.","journal-title":"Gynecol Oncol"},{"key":"2551_CR15","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1006\/gyno.1998.5184","volume":"72","author":"H Pickel","year":"1999","unstructured":"Pickel H, Lahousen M, Petru E, Stettner H, Hackl A, Kapp K, et al: Consolidation radiotherapy after carboplatin-based chemotherapy in radically operated advanced ovarian cancer. Gynecol Oncol. 1999, 72: 215-219. 10.1006\/gyno.1998.5184.","journal-title":"Gynecol Oncol"},{"key":"2551_CR16","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1006\/gyno.1993.1253","volume":"51","author":"GM Thomas","year":"1993","unstructured":"Thomas GM: Is there a role for consolidation or salvage radiotherapy after chemotherapy in advanced epithelial ovarian cancer?. Gynecol Oncol. 1993, 51: 97-103. 10.1006\/gyno.1993.1253.","journal-title":"Gynecol Oncol"},{"key":"2551_CR17","doi-asserted-by":"publisher","first-page":"1710","DOI":"10.1002\/cncr.2820710441","volume":"71","author":"GM Thomas","year":"1993","unstructured":"Thomas GM, Dembo AJ: Integrating radiation therapy into the management of ovarian cancer. Cancer. 1993, 71: 1710-1718. 10.1002\/1097-0142(19930315)71:6<1977::AID-CNCR2820710609>3.0.CO;2-D.","journal-title":"Cancer"},{"key":"2551_CR18","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1046\/j.1525-1438.2003.13193.x","volume":"13","author":"B Sorbe","year":"2003","unstructured":"Sorbe B: Consolidation treatment of advanced (FIGO stage III) ovarian carcinoma in complete surgical remission after induction chemotherapy: a randomized, controlled, clinical trial comparing whole abdominal radiotherapy, chemotherapy, and no further treatment. Int J Gynecol Cancer. 2003, 13: 278-286. 10.1046\/j.1525-1438.2003.13193.x.","journal-title":"Int J Gynecol Cancer"},{"key":"2551_CR19","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/S0167-8140(99)00144-9","volume":"53","author":"N Einhorn","year":"1999","unstructured":"Einhorn N, Lundell M, Nilsson B, Ragnarsson-Olding B, Sjovall K: Is there place for radiotherapy in the treatment of advanced ovarian cancer?. Radiother Oncol. 1999, 53: 213-218. 10.1016\/S0167-8140(99)00144-9.","journal-title":"Radiother Oncol"},{"key":"2551_CR20","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1080\/02841860310014426","volume":"42","author":"N Einhorn","year":"2003","unstructured":"Einhorn N, Trope C, Ridderheim M, Boman K, Sorbe B, Cavallin-Stahl E: A systematic overview of radiation therapy effects in ovarian cancer. Acta Oncol. 2003, 42: 562-566. 10.1080\/02841860310014426.","journal-title":"Acta Oncol"},{"key":"2551_CR21","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1016\/S0360-3016(98)00066-2","volume":"41","author":"AW Fyles","year":"1998","unstructured":"Fyles AW, Thomas GM, Pintilie M, Ackerman I, Levin W: A randomized study of two doses of abdominopelvic radiation therapy for patients with optimally debulked Stage I, II, and III ovarian cancer. Int J Radiat Oncol Biol Phys. 1998, 41: 543-549. 10.1016\/S0360-3016(98)00066-2.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2551_CR22","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.ijrobp.2004.09.010","volume":"62","author":"R Dinniwell","year":"2005","unstructured":"Dinniwell R, Lock M, Pintilie M, Fyles A, Laframboise S, Depetrillo D, et al: Consolidative abdominopelvic radiotherapy after surgery and carboplatin\/paclitaxel chemotherapy for epithelial ovarian cancer. Int J Radiat Oncol Biol Phys. 2005, 62: 104-110. 10.1016\/j.ijrobp.2004.09.010.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2551_CR23","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1016\/0360-3016(92)90779-H","volume":"22","author":"TJ Whelan","year":"1992","unstructured":"Whelan TJ, Dembo AJ, Bush RS, Sturgeon JF, Fine S, Pringle JF, et al: Complications of whole abdominal and pelvic radiotherapy following chemotherapy for advanced ovarian cancer. Int J Radiat Oncol Biol Phys. 1992, 22: 853-858. 10.1016\/0360-3016(92)90779-H.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2551_CR24","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1200\/JCO.1987.5.6.897","volume":"5","author":"DB Fuller","year":"1987","unstructured":"Fuller DB, Sause WT, Plenk HP, Menlove RL: Analysis of postoperative radiation therapy in stage I through III epithelial ovarian carcinoma. J Clin Oncol. 1987, 5: 897-905.","journal-title":"J Clin Oncol"},{"key":"2551_CR25","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1016\/S0360-3016(03)00663-1","volume":"57","author":"W Duthoy","year":"2003","unstructured":"Duthoy W, De Gersem W, Vergote K, Coghe M, Boterberg T, De Deene Y, et al: Whole abdominopelvic radiotherapy (WAPRT) using intensity-modulated arc therapy (IMAT): first clinical experience. Int J Radiat Oncol Biol Phys. 2003, 57: 1019-1032. 10.1016\/S0360-3016(03)00663-1.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2551_CR26","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1007\/s00066-008-1772-z","volume":"184","author":"N Rochet","year":"2008","unstructured":"Rochet N, Sterzing F, Jensen A, Dinkel J, Herfarth K, Schubert K, et al: Helical tomotherapy as a new treatment technique for whole abdominal irradiation. Strahlenther Onkol. 2008, 184: 145-149. 10.1007\/s00066-008-1772-z.","journal-title":"Strahlenther Onkol"},{"key":"2551_CR27","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1159\/000061325","volume":"36","author":"J Debus","year":"2002","unstructured":"Debus J, Zierhut D, Didinger B, Schlegel W, Wannenmacher M: Inverse planning and intensity-modulated radiotherapy in patients with prostate cancer. Front Radiat Ther Oncol. 2002, 36: 25-34. full_text.","journal-title":"Front Radiat Ther Oncol"},{"key":"2551_CR28","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1016\/S0360-3016(02)02921-8","volume":"54","author":"L Hong","year":"2002","unstructured":"Hong L, Alektiar K, Chui C, LoSasso T, Hunt M, Spirou S, et al: IMRT of large fields: whole-abdomen irradiation. Int J Radiat Oncol Biol Phys. 2002, 54: 278-289. 10.1016\/S0360-3016(02)03298-4.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2551_CR29","doi-asserted-by":"publisher","first-page":"1709","DOI":"10.1118\/1.596958","volume":"20","author":"TR Mackie","year":"1993","unstructured":"Mackie TR, Holmes T, Swerdloff S, Reckwerdt P, Deasy JO, Yang J, et al: Tomotherapy: a new concept for the delivery of dynamic conformal radiotherapy. Med Phys. 1993, 20: 1709-1719. 10.1118\/1.596958.","journal-title":"Med Phys"},{"key":"2551_CR30","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1186\/1471-2407-7-227","volume":"7","author":"N Rochet","year":"2007","unstructured":"Rochet N, Jensen AD, Sterzing F, Munter MW, Eichbaum MH, Schneeweiss A, et al: Adjuvant whole abdominal intensity modulated radiotherapy (IMRT) for high risk stage FIGO III patients with ovarian cancer (OVAR-IMRT-01) - Pilot trial of a phase I\/II study: study protocol. BMC Cancer. 2007, 7: 227-10.1186\/1471-2407-7-227.","journal-title":"BMC Cancer"},{"key":"2551_CR31","doi-asserted-by":"publisher","first-page":"1382","DOI":"10.1016\/j.ijrobp.2009.03.061","volume":"76","author":"N Rochet","year":"2010","unstructured":"Rochet N, Sterzing F, Jensen AD, Dinkel J, Herfarth KK, Schubert K, et al: Intensity-modulated whole abdominal radiotherapy after surgery and carboplatin\/taxane chemotherapy for advanced ovarian cancer: phase I study. Int J Radiat Oncol Biol Phys. 2010, 76: 1382-1389. 10.1016\/j.ijrobp.2009.03.061.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2551_CR32","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/S0360-3016(03)00510-8","volume":"57","author":"S Firat","year":"2003","unstructured":"Firat S, Murray K, Erickson B: High-dose whole abdominal and pelvic irradiation for treatment of ovarian carcinoma: long-term toxicity and outcomes. Int J Radiat Oncol Biol Phys. 2003, 57: 201-207. 10.1016\/S0360-3016(03)00510-8.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2551_CR33","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1016\/0360-3016(92)90778-G","volume":"22","author":"AW Fyles","year":"1992","unstructured":"Fyles AW, Dembo AJ, Bush RS, Levin W, Manchul LA, Pringle JF, et al: Analysis of complications in patients treated with abdomino-pelvic radiation therapy for ovarian carcinoma. Int J Radiat Oncol Biol Phys. 1992, 22: 847-851. 10.1016\/0360-3016(92)90778-G.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2551_CR34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0197-2456(89)90015-9","volume":"10","author":"R Simon","year":"1989","unstructured":"Simon R: Optimal two-stage designs for phase II clinical trials. Control Clin Trials. 1989, 10: 1-10. 10.1016\/0197-2456(89)90015-9.","journal-title":"Control Clin Trials"},{"key":"2551_CR35","volume-title":"Adaptive designs for single-arm, phase II trials in oncology, Internal Report","author":"S Englert","year":"2010","unstructured":"Englert S, Kieser M: Adaptive designs for single-arm, phase II trials in oncology, Internal Report. 2010"}],"container-title":["BMC Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2407-11-41.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2407-11-41\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2407-11-41","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,19]],"date-time":"2017-06-19T19:31:50Z","timestamp":1497900710000},"score":1,"resource":{"primary":{"URL":"http:\/\/bmccancer.biomedcentral.com\/articles\/10.1186\/1471-2407-11-41"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1,28]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["2551"],"URL":"https:\/\/doi.org\/10.1186\/1471-2407-11-41","relation":{},"ISSN":["1471-2407"],"issn-type":[{"value":"1471-2407","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,1,28]]},"article-number":"41"}}