{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T13:02:03Z","timestamp":1775307723160,"version":"3.50.1"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2012,3,21]],"date-time":"2012-03-21T00:00:00Z","timestamp":1332288000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Cancer"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1186\/1471-2407-12-102","type":"journal-article","created":{"date-parts":[[2012,3,22]],"date-time":"2012-03-22T23:09:18Z","timestamp":1332457758000},"source":"Crossref","is-referenced-by-count":35,"title":["Interleukin-10-819 promoter polymorphism in association with gastric cancer risk"],"prefix":"10.1186","volume":"12","author":[{"given":"Huiping","family":"Xue","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bing","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianfu","family":"An","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuyuan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gang","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,3,21]]},"reference":[{"issue":"5","key":"3166_CR1","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1097\/CEJ.0b013e3283465426","volume":"20","author":"V Jooste","year":"2011","unstructured":"Jooste V, Remontet L, Colonna M, Belot A, Launoy G, Binder F, Faivre J, Bouvier AM: Trends in the incidence of digestive cancers in France between 1980 and 2005 and projections for the year 2010. Eur J Cancer Prev. 2011, 20 (5): 375-380.","journal-title":"Eur J Cancer Prev"},{"issue":"12","key":"3166_CR2","doi-asserted-by":"publisher","first-page":"2893","DOI":"10.1002\/ijc.25516","volume":"127","author":"J Ferlay","year":"2010","unstructured":"Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM: Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010, 127 (12): 2893-2917. doi:10.1002\/ijc.25516","journal-title":"Int J Cancer"},{"key":"3166_CR3","volume-title":"J Surg Oncol","author":"V Valenti","year":"2011","unstructured":"Valenti V, Hernandez-Lizoa\u00edn JL, Beorlegui MC, Diaz-Gozalez JA, Regueira FM, Rodriguez JJ, Viudez A, Sola I, Cienfuegos JA: Morbidity, mortality, and pathological response in patients with gastric cancer preoperatively treated with chemotherapy or chemoradiotherapy. J Surg Oncol. 2011, doi: 10.1002\/jso.21947,"},{"issue":"1","key":"3166_CR4","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1111\/j.1440-1746.2008.05753.x","volume":"24","author":"K Wu","year":"2009","unstructured":"Wu K, Nie Y, Guo C, Chen Y, Ding J, Fan D: Molecular basis of therapeutic approaches to gastric cancer. J Gastroenterol Hepatol. 2009, 24 (1): 37-41. 10.1111\/j.1440-1746.2008.05686.x.","journal-title":"J Gastroenterol Hepatol"},{"issue":"1","key":"3166_CR5","doi-asserted-by":"publisher","first-page":"17","DOI":"10.3748\/wjg.v12.i1.17","volume":"12","author":"L Yang","year":"2006","unstructured":"Yang L: Incidence and mortality of gastric cancer in China. World J Gastroenterol. 2006, 12 (1): 17-20.","journal-title":"World J Gastroenterol"},{"issue":"15","key":"3166_CR6","doi-asserted-by":"publisher","first-page":"1175","DOI":"10.1056\/NEJMra020542","volume":"347","author":"S Suerbaum","year":"2002","unstructured":"Suerbaum S, Michetti P: Helicobacter pylori infection. N Engl J Med. 2002, 347 (15): 1175-1186.","journal-title":"N Engl J Med"},{"issue":"10","key":"3166_CR7","doi-asserted-by":"publisher","first-page":"1604","DOI":"10.1111\/j.1440-1746.2010.06428.x","volume":"25","author":"H Xue","year":"2010","unstructured":"Xue H, Lin B, Ni P, Xu H, Huang G: Interleukin-1B and interleukin-1 RN polymorphisms and gastric carcinoma risk: a meta-analysis. J Gastroenterol Hepatol. 2010, 25 (10): 1604-1617.","journal-title":"J Gastroenterol Hepatol"},{"issue":"4","key":"3166_CR8","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1093\/aje\/kwq378","volume":"173","author":"H Xue","year":"2011","unstructured":"Xue H, Ni P, Lin B, Xu H, Huang G: X-Ray Repair Cross-Complementing Group 1 (XRCC1) Genetic Polymorphisms and Gastric Cancer Risk: A HuGE Review and Meta-Analysis. Am J Epidemiol. 2011, 173 (4): 363-375. 10.1093\/aje\/kwq378. Epub 2011 Jan 7","journal-title":"Am J Epidemiol"},{"issue":"11","key":"3166_CR9","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1089\/dna.2011.1257","volume":"30","author":"Y Cui","year":"2011","unstructured":"Cui Y, Xue H, Lin B, Ni P, Fang JY: A Meta-Analysis of CDH1 C-160A Genetic Polymorphism and Gastric Cancer Risk. DNA Cell Biol. 2011, 30 (11): 937-945. 10.1089\/dna.2011.1257. Epub 2011 May 25","journal-title":"DNA Cell Biol"},{"issue":"5","key":"3166_CR10","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1189\/jlb.0705358","volume":"78","author":"S Mocellin","year":"2005","unstructured":"Mocellin S, Marincola FM, Young HA: Interleukin-10 and the immune response against cancer: a counterpoint. J Leukoc Biol. 2005, 78 (5): 1043-1051. 10.1189\/jlb.0705358. Epub 2005 Oct 4","journal-title":"J Leukoc Biol"},{"issue":"2","key":"3166_CR11","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1007\/BF02303803","volume":"4","author":"K Avradopoulos","year":"1997","unstructured":"Avradopoulos K, Mehta S, Blackinton D, Wanebo HJ: Interleukin-10 as a possible mediator of immunosuppressive effect in patients with squamous cell carcinoma of the head and neck. Ann Surg Oncol. 1997, 4 (2): 184-190.","journal-title":"Ann Surg Oncol"},{"issue":"1","key":"3166_CR12","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1182\/blood.V93.1.208","volume":"93","author":"GQ Perrin","year":"1999","unstructured":"Perrin GQ, Johnson HM, Subramaniam PS: Mechanism of interleukin-10 inhibition of T-helper cell activation by superantigen at the level of the cell cycle. Blood. 1999, 93 (1): 208-216.","journal-title":"Blood"},{"issue":"1","key":"3166_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1365-2370.1997.tb00001.x","volume":"24","author":"DM Turner","year":"1997","unstructured":"Turner DM, Williams DM, Sankaran D, Lazarus M, Sinnott PJ, Hutchinson IV: An investigation of polymorphism in the interleukin-10 gene promoter. Eur J Immunogenet. 1997, 24 (1): 1-8. 10.1111\/j.1365-2370.1997.tb00001.x.","journal-title":"Eur J Immunogenet"},{"issue":"5","key":"3166_CR14","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1002\/ijc.10987","volume":"104","author":"MS Wu","year":"2003","unstructured":"Wu MS, Wu CY, Chen CJ, Lin MT, Shun CT, Lin JT: Interleukin-10 genotypes associate with the risk of gastric carcinoma in Taiwanese Chinese. Int J Cancer. 2003, 104 (5): 617-623. 10.1002\/ijc.10987.","journal-title":"Int J Cancer"},{"issue":"9","key":"3166_CR15","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1158\/1055-9965.1547.13.9","volume":"13","author":"SA Savage","year":"2004","unstructured":"Savage SA, Abnet CC, Haque K, Mark SD, Qiao YL, Dong ZW, Dawsey SM, Taylor PR, Chanock SJ: Polymorphisms in interleukin -2, -6, and -10 are not associated with gastric cardia or esophageal cancer in a high-risk chinese population. Cancer Epidemiol Biomarkers Prev. 2004, 13 (9): 1547-1549.","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"4","key":"3166_CR16","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1007\/s10238-005-0082-3","volume":"5","author":"W Alp\u00edzar-Alp\u00edzar","year":"2005","unstructured":"Alp\u00edzar-Alp\u00edzar W, P\u00e9rez-P\u00e9rez GI, Une C, Cuenca P, Sierra R: Association of interleukin-1B and interleukin-1RN polymorphisms with gastric cancer in a high-risk population of Costa Rica. Clin Exp Med. 2005, 5 (4): 169-176. 10.1007\/s10238-005-0082-3.","journal-title":"Clin Exp Med"},{"issue":"4","key":"3166_CR17","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.cyto.2004.10.013","volume":"29","author":"CF Zambon","year":"2005","unstructured":"Zambon CF, Basso D, Navaglia F, Belluco C, Falda A, Fogar P, Greco E, Gallo N, Rugge M, Di Mario F, Plebani M: Pro- and anti-inflammatory cytokines gene polymorphisms and Helicobacter pylori infection: interactions influence outcome. Cytokine. 2005, 29 (4): 141-152. 10.1016\/j.cyto.2004.10.013. Epub 2004 Dec 8","journal-title":"Cytokine"},{"issue":"1","key":"3166_CR18","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1007\/s10552-005-0439-7","volume":"17","author":"F Kamangar","year":"2006","unstructured":"Kamangar F, Abnet CC, Hutchinson AA, Newschaffer CJ, Helzlsouer K, Shugart YY, Pietinen P, Dawsey SM, Albanes D, Virtamo J, Taylor PR: Polymorphisms in inflammation-related genes and risk of gastric cancer (Finland). Cancer Causes Control. 2006, 17 (1): 117-125. 10.1007\/s10552-005-0439-7.","journal-title":"Cancer Causes Control"},{"issue":"9","key":"3166_CR19","doi-asserted-by":"publisher","first-page":"1443","DOI":"10.1111\/j.1440-1746.2006.04613.x","volume":"22","author":"M Sugimoto","year":"2007","unstructured":"Sugimoto M, Furuta T, Shirai N, Nakamura A, Kajimura M, Sugimura H, Hishida A: Effects of interleukin-10 gene polymorphism on the development of gastric cancer and peptic ulcer in Japanese subjects. J Gastroenterol Hepatol. 2007, 22 (9): 1443-1449. 10.1111\/j.1440-1746.2006.04613.x.","journal-title":"J Gastroenterol Hepatol"},{"issue":"11","key":"3166_CR20","doi-asserted-by":"publisher","first-page":"1894","DOI":"10.1093\/annonc\/mdn400","volume":"19","author":"JB Crusius","year":"2008","unstructured":"Crusius JB, Canzian F, Capell\u00e1 G, Pe\u00f1a AS, Pera G, Sala N, Agudo A, Rico F, Del Giudice G, Palli D, Plebani M, Boeing H, Bueno-de-Mesquita HB, Carneiro F, Pala V, Save VE, Vineis P, Tumino R, Panico S, Berglund G, Manjer J, Stenling R, Hallmans G, Mart\u00ednez C, Dorronsoro M, Barricarte A, Navarro C, Quir\u00f3s JR, Allen N, Key TJ, Binghan S, Caldas C, Linseisen J, Kaaks R, Overvad K, Tj\u00f8nneland A, B\u00fcchner FC, Peeters PH, Numans ME, Clavel-Chapelon F, Trichopoulou A, Lund E, Jenab M, Rinaldi S, Ferrari P, Riboli E, Gonz\u00e1lez CA: Cytokine gene polymorphisms and the risk of adenocarcinoma of the stomach in the European prospective investigation into cancer and nutrition (EPIC-EURGAST). Ann Oncol. 2008, 19 (11): 1894-1902. 10.1093\/annonc\/mdn400. Epub 2008 Jul 14","journal-title":"Ann Oncol"},{"issue":"4","key":"3166_CR21","first-page":"423","volume":"26","author":"H Xiao","year":"2009","unstructured":"Xiao H, Jiang Y, Li R, Xia B: Association of IL-10 gene polymorphisms with gastroduodenal diseases in Hubei Han population. Chin J Med Genet. 2009, 26 (4): 423-426. Published in China","journal-title":"Chin J Med Genet"},{"issue":"9","key":"3166_CR22","first-page":"811","volume":"22","author":"SP SU","year":"2010","unstructured":"SU SP, Yang ZB, Tian YL, Xiang Y, Wu M, Ma XJ: Association between IL -10-819 C\/C and TNF-\u03b1-1031 C\/C genes and susceptibility of gastroduodenal diseases. Chin J Microecology. 2010, 22 (9): 811-815. [Published in China]","journal-title":"Chin J Microecology"},{"issue":"10","key":"3166_CR23","doi-asserted-by":"publisher","first-page":"1362","DOI":"10.3748\/wjg.v17.i10.1362","volume":"17","author":"J Liu","year":"2011","unstructured":"Liu J, Song B, Wang JL, Li ZJ, Li WH, Wang ZH: Polymorphisms of interleukin-10 promoter are not associated with prognosis of advanced gastric cancer. World J Gastroenterol. 2011, 17 (10): 1362-1367.","journal-title":"World J Gastroenterol"},{"issue":"5","key":"3166_CR24","doi-asserted-by":"publisher","first-page":"1008","DOI":"10.3945\/jn.108.101865","volume":"139","author":"KP Ko","year":"2009","unstructured":"Ko KP, Park SK, Cho LY, Gwack J, Yang JJ, Shin A, Kim CS, Kim Y, Kang D, Chang SH, Shin HR, Yoo KY: Soybean product intake modifies the association between interleukin-10 genetic polymorphisms and gastric cancer risk. J Nutr. 2009, 139 (5): 1008-1012. 10.3945\/jn.108.101865. Epub 2009 Mar 25","journal-title":"J Nutr"},{"issue":"2","key":"3166_CR25","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1007\/BF03256358","volume":"14","author":"F Sun","year":"2010","unstructured":"Sun F, Sun Y, Yu Z, Zhang D, Zhang J, Song B, Zheng H: Interleukin-10 gene polymorphisms influence susceptibility to cachexia in patients with low-third gastric cancer in a Chinese population. Mol Diagn Ther. 2010, 14 (2): 95-100.","journal-title":"Mol Diagn Ther"},{"issue":"1","key":"3166_CR26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1177\/147323001003800101","volume":"38","author":"KF Chen","year":"2010","unstructured":"Chen KF, Li B, Wei YG, Peng CJ: Interleukin-10-819 promoter polymorphism associated with gastric cancer among Asians. J Int Med Res. 2010, 38 (1): 1-8.","journal-title":"J Int Med Res"},{"issue":"3","key":"3166_CR27","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1093\/aje\/kwi184","volume":"162","author":"A Thakkinstian","year":"2005","unstructured":"Thakkinstian A, McEvoy M, Minelli C, Gibson P, Hancox B, Duffy D, Thompson J, Hall I, Kaufman J, Leung TF, Helms PJ, Hakonarson H, Halpi E, Navon R, Attia J: Systematic review and metaanalysis of the association between{h}2-adrenoceptor polymorphisms and asthma: a HuGE review. Am J Epidemiol. 2005, 162 (3): 201-211.","journal-title":"Am J Epidemiol"},{"issue":"9","key":"3166_CR28","doi-asserted-by":"publisher","first-page":"1674","DOI":"10.1158\/1055-9965.EPI-06-0189","volume":"15","author":"MC Camargo","year":"2006","unstructured":"Camargo MC, Mera R, Correa P, Peek RM, Fontham ET, Goodman KJ, Piazuelo MB, Sicinschi L, Zabaleta J, Schneider BG: Interleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms and gastric cancer: a meta-analysis. Cancer Epidemiol Biomarkers Prev. 2006, 15 (9): 1674-1687.","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"9","key":"3166_CR29","doi-asserted-by":"publisher","first-page":"1291","DOI":"10.1002\/sim.2010","volume":"24","author":"A Thakkinstian","year":"2005","unstructured":"Thakkinstian A, McElduff P, D'Este C, Duffy D, Attia J: A method for meta-analysis of molecular association studies. Stat Med. 2005, 24 (9): 1291-1306.","journal-title":"Stat Med"},{"issue":"12","key":"3166_CR30","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1007\/BF01200731","volume":"120","author":"G Heidl","year":"1993","unstructured":"Heidl G, Langhans P, Mellin W, Bunte H, Grundmann E: Adeno-carcinomas of esophagus and cardia in comparison with gastric carcinoma. J Cancer Res Clin Oncol. 1993, 120 (12): 95-99.","journal-title":"J Cancer Res Clin Oncol"},{"issue":"7","key":"3166_CR31","doi-asserted-by":"publisher","first-page":"1439","DOI":"10.1002\/cncr.20966","volume":"103","author":"MA Kim","year":"2005","unstructured":"Kim MA, Lee HS, Yang HK, Kim WH: Clinicopathologic and protein expression differences betweencardia carcinoma and noncardia carcinoma of the stomach. Cancer. 2005, 103 (7): 1439-1446.","journal-title":"Cancer"},{"issue":"10","key":"3166_CR32","doi-asserted-by":"publisher","first-page":"1864","DOI":"10.1007\/s00268-005-0582-z","volume":"30","author":"H Saito","year":"2006","unstructured":"Saito H, Fukumoto Y, Osaki T, Fukuda K, Tatebe S, Tsujitani S, Ikeguchi M: Distinct recurrence pattern and outcome of adenocarcinoma of the gastric cardia in comparison with carcinoma of other regions of the stomach. World J Surg. 2006, 30 (10): 1864-1869.","journal-title":"World J Surg"},{"issue":"11","key":"3166_CR33","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1056\/NEJMoa001999","volume":"345","author":"N Uemura","year":"2001","unstructured":"Uemura N, Okamoto S, Yamamoto S, Matsumura N, Yamaguchi S, Yamakido M, Taniyama K, Sasaki N, Schlemper RJ: Helicobacter pylori infection and the development of gastric cancer. N Engl J Med. 2001, 345 (11): 784-789.","journal-title":"N Engl J Med"},{"key":"3166_CR34","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1186\/1471-2407-10-456","volume":"10","author":"J Liu","year":"2010","unstructured":"Liu J, Song B, Bai X, Liu W, Li Z, Wang J, Zheng Y, Wang Z: Association of genetic polymorphisms in the interleukin-10 promoter with risk of prostate cancer in Chinese. BMC Cancer. 2010, 10: 456-10.1186\/1471-2407-10-456.","journal-title":"BMC Cancer"},{"issue":"12","key":"3166_CR35","first-page":"3369","volume":"62","author":"SL McCarron","year":"2002","unstructured":"McCarron SL, Edwards S, Evans PR, Gibbs R, Dearnaley DP, Dowe A, Southgate C, Easton DF, Eeles RA, Howell WM: Influence of cytokine gene polymorphisms on the development of prostate cancer. Cancer Res. 2002, 62 (12): 3369-3372.","journal-title":"Cancer Res"},{"issue":"1","key":"3166_CR36","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1093\/ije\/dym234","volume":"37","author":"C Minelli","year":"2008","unstructured":"Minelli C, Thompson JR, Abrams KR, Thakkinstian A, Attia J: How should we use information about HWE in the meta-analyses of genetic association studies?. Int J Epidemiol. 2008, 37 (1): 136-146. 10.1093\/ije\/dym277.","journal-title":"Int J Epidemiol"}],"container-title":["BMC Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2407-12-102.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2407-12-102\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2407-12-102","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,21]],"date-time":"2023-06-21T10:22:15Z","timestamp":1687342935000},"score":1,"resource":{"primary":{"URL":"http:\/\/bmccancer.biomedcentral.com\/articles\/10.1186\/1471-2407-12-102"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3,21]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["3166"],"URL":"https:\/\/doi.org\/10.1186\/1471-2407-12-102","relation":{},"ISSN":["1471-2407"],"issn-type":[{"value":"1471-2407","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,3,21]]},"article-number":"102"}}