{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T14:50:24Z","timestamp":1790261424132,"version":"4.1.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2013,10,19]],"date-time":"2013-10-19T00:00:00Z","timestamp":1382140800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Cancer"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1186\/1471-2407-13-484","type":"journal-article","created":{"date-parts":[[2013,10,19]],"date-time":"2013-10-19T03:01:40Z","timestamp":1382151700000},"source":"Crossref","is-referenced-by-count":71,"title":["Germline mutation in the RAD51B gene confers predisposition to breast cancer"],"prefix":"10.1186","volume":"13","author":[{"given":"Lisa","family":"Golmard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginie","family":"Caux-Moncoutier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gr\u00e9goire","family":"Davy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Essam","family":"Al Ageeli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Poirot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carole","family":"Tirapo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doroth\u00e9e","family":"Michaux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Barbaroux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine Dubois","family":"d\u2019Enghien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Nicolas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Cast\u00e9ra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Sastre-Garau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc-Henri","family":"Stern","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claude","family":"Houdayer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Stoppa-Lyonnet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,10,19]]},"reference":[{"key":"4118_CR1","doi-asserted-by":"publisher","first-page":"69","DOI":"10.3322\/caac.20107","volume":"61","author":"A Jemal","year":"2011","unstructured":"Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D: Global cancer statistics. CA Cancer J Clin. 2011, 61: 69-90. 10.3322\/caac.20107.","journal-title":"CA Cancer J Clin"},{"key":"4118_CR2","first-page":"232","volume":"48","author":"EB Claus","year":"1991","unstructured":"Claus EB, Risch N, Thompson WD: Genetic analysis of breast cancer in the cancer and steroid hormone study. Am J Hum Genet. 1991, 48: 232-242.","journal-title":"Am J Hum Genet"},{"key":"4118_CR3","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1126\/science.7545954","volume":"266","author":"Y Miki","year":"1994","unstructured":"Miki Y, Swensen J, Shattuck-Eidens D, Futreal PA, Harshman K, Tavtigian S, Liu Q, Cochran C, Bennett LM, Ding W, Bell R, Rosenthal J, Hussey C, Tran T, McClure M, Frye C, Hattier T, Phelps R, Haugen-Strano A, Katcher H, Yakumo K, Gholami Z, Shaffer D, Stone S, Bayer S, Wray C, Bogden R, Dayananth P, Ward J, Tonin P, et al: A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science. 1994, 266: 66-71. 10.1126\/science.7545954.","journal-title":"Science"},{"key":"4118_CR4","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1038\/378789a0","volume":"378","author":"R Wooster","year":"1995","unstructured":"Wooster R, Bignell G, Lancaster J, Swift S, Seal S, Mangion J, Collins N, Gregory S, Gumbs C, Micklem G: Identification of the breast cancer susceptibility gene BRCA2. Nature. 1995, 378: 789-792. 10.1038\/378789a0.","journal-title":"Nature"},{"key":"4118_CR5","doi-asserted-by":"publisher","first-page":"2796","DOI":"10.1056\/NEJMsa0708739","volume":"358","author":"PD Pharoah","year":"2008","unstructured":"Pharoah PD, Antoniou AC, Easton DF, Ponder BA: Polygenes, risk prediction, and targeted prevention of breast cancer. N Engl J Med. 2008, 358: 2796-2803. 10.1056\/NEJMsa0708739.","journal-title":"N Engl J Med"},{"key":"4118_CR6","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.ccr.2007.01.010","volume":"11","author":"T Walsh","year":"2007","unstructured":"Walsh T, King MC: Ten genes for inherited breast cancer. Cancer Cell. 2007, 11: 103-105. 10.1016\/j.ccr.2007.01.010.","journal-title":"Cancer Cell"},{"key":"4118_CR7","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1038\/ng1902","volume":"38","author":"S Seal","year":"2006","unstructured":"Seal S, Thompson D, Renwick A, Elliott A, Kelly P, Barfoot R, Chagtai T, Jayatilake H, Ahmed M, Spanova K, North B, McGuffog L, Evans DG, Eccles D, Easton DF, Stratton MR, Rahman N, Breast Cancer Susceptibility Collaboration (UK): Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles. Nat Genet. 2006, 38: 1239-1241. 10.1038\/ng1902.","journal-title":"Nat Genet"},{"key":"4118_CR8","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1038\/ng1959","volume":"39","author":"N Rahman","year":"2007","unstructured":"Rahman N, Seal S, Thompson D, Kelly P, Renwick A, Elliott A, Reid S, Spanova K, Barfoot R, Chagtai T, Jayatilake H, McGuffog L, Hanks S, Evans DG, Eccles D, Easton DF, Stratton MR, Breast Cancer Susceptibility Collaboration (UK): PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene. Nat Genet. 2007, 39: 165-167. 10.1038\/ng1959.","journal-title":"Nat Genet"},{"key":"4118_CR9","doi-asserted-by":"publisher","first-page":"2143","DOI":"10.1056\/NEJMra0802968","volume":"359","author":"WD Foulkes","year":"2008","unstructured":"Foulkes WD: Inherited susceptibility to common cancers. N Engl J Med. 2008, 359: 2143-2153. 10.1056\/NEJMra0802968.","journal-title":"N Engl J Med"},{"key":"4118_CR10","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1126\/science.1073834","volume":"297","author":"NG Howlett","year":"2002","unstructured":"Howlett NG, Taniguchi T, Olson S, Cox B, Waisfisz Q, De Die-Smulders C, Persky N, Grompe M, Joenje H, Pals G, Ikeda H, Fox EA, D\u2019Andrea AD: Biallelic inactivation of BRCA2 in Fanconi anemia. Science. 2002, 297: 606-609. 10.1126\/science.1073834.","journal-title":"Science"},{"key":"4118_CR11","doi-asserted-by":"publisher","first-page":"934","DOI":"10.1038\/ng1625","volume":"37","author":"M Levitus","year":"2005","unstructured":"Levitus M, Waisfisz Q, Godthelp BC, de Vries Y, Hussain S, Wiegant WW, Elghalbzouri-Maghrani E, Steltenpool J, Rooimans MA, Pals G, Arwert F, Mathew CG, Zdzienicka MZ, Hiom K, De Winter JP, Joenje H: The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J. Nat Genet. 2005, 37: 934-935. 10.1038\/ng1625.","journal-title":"Nat Genet"},{"key":"4118_CR12","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1038\/ng1947","volume":"39","author":"S Reid","year":"2007","unstructured":"Reid S, Schindler D, Hanenberg H, Barker K, Hanks S, Kalb R, Neveling K, Kelly P, Seal S, Freund M, Wurm M, Batish SD, Lach FP, Yetgin S, Neitzel H, Ariffin H, Tischkowitz M, Mathew CG, Auerbach AD, Rahman N: Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer. Nat Genet. 2007, 39: 162-164. 10.1038\/ng1947.","journal-title":"Nat Genet"},{"key":"4118_CR13","doi-asserted-by":"publisher","first-page":"898","DOI":"10.1016\/j.semcdb.2011.07.019","volume":"22","author":"N Suwaki","year":"2011","unstructured":"Suwaki N, Klare K, Tarsounas M: RAD51 paralogs: roles in DNA damage signalling, recombinational repair and tumorigenesis. Semin Cell Dev Biol. 2011, 22: 898-905. 10.1016\/j.semcdb.2011.07.019.","journal-title":"Semin Cell Dev Biol"},{"key":"4118_CR14","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1038\/ng.570","volume":"42","author":"F Vaz","year":"2010","unstructured":"Vaz F, Hanenberg H, Schuster B, Barker K, Wiek C, Erven V, Neveling K, Endt D, Kesterton I, Autore F, Fraternali F, Freund M, Hartmann L, Grimwade D, Roberts RG, Schaal H, Mohammed S, Rahman N, Schindler D, Mathew CG: Mutation of the RAD51C gene in a Fanconi anemia-like disorder. Nat Genet. 2010, 42: 406-409. 10.1038\/ng.570.","journal-title":"Nat Genet"},{"key":"4118_CR15","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1136\/jmedgenet-2011-100585","volume":"49","author":"HE Shamseldin","year":"2012","unstructured":"Shamseldin HE, Elfaki M, Alkuraya FS: Exome sequencing reveals a novel Fanconi group defined by XRCC2 mutation. J Med Genet. 2012, 49: 184-186. 10.1136\/jmedgenet-2011-100585.","journal-title":"J Med Genet"},{"key":"4118_CR16","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1038\/ng.569","volume":"42","author":"A Meindl","year":"2010","unstructured":"Meindl A, Hellebrand H, Wiek C, Erven V, Wappenschmidt B, Niederacher D, Freund M, Lichtner P, Hartmann L, Schaal H, Ramser J, Honisch E, Kubisch C, Wichmann HE, Kast K, Deissler H, Engel C, M\u00fcller-Myhsok B, Neveling K, Kiechle M, Mathew CG, Schindler D, Schmutzler RK, Hanenberg H: Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. Nat Genet. 2010, 42: 410-414. 10.1038\/ng.569.","journal-title":"Nat Genet"},{"key":"4118_CR17","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1038\/ng.893","volume":"43","author":"C Loveday","year":"2011","unstructured":"Loveday C, Turnbull C, Ramsay E, Hughes D, Ruark E, Frankum JR, Bowden G, Kalmyrzaev B, Warren-Perry M, Snape K, Adlard JW, Barwell J, Berg J, Brady AF, Brewer C, Brice G, Chapman C, Cook J, Davidson R, Donaldson A, Douglas F, Greenhalgh L, Henderson A, Izatt L, Kumar A, Lalloo F, Miedzybrodzka Z, Morrison PJ, Paterson J, Porteous M, et al: Germline mutations in RAD51D confer susceptibility to ovarian cancer. Nat Genet. 2011, 43: 879-882. 10.1038\/ng.893.","journal-title":"Nat Genet"},{"key":"4118_CR18","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1016\/j.ajhg.2012.02.027","volume":"90","author":"DJ Park","year":"2012","unstructured":"Park DJ, Lesueur F, Nguyen-Dumont T, Pertesi M, Odefrey F, Hammet F, Neuhausen SL, John EM, Andrulis IL, Terry MB, Daly M, Buys S, Le Calvez-Kelm F, Lonie A, Pope BJ, Tsimiklis H, Voegele C, Hilbers FM, Hoogerbrugge N, Barroso A, Osorio A, Giles GG, Devilee P, Benitez J, Hopper JL, Tavtigian SV, Goldgar DE, Southey MC, Breast Cancer Family Registry: Rare mutations in XRCC2 increase the risk of breast cancer. Am J Hum Genet. 2012, 90: 734-739. 10.1016\/j.ajhg.2012.02.027. 13","journal-title":"Am J Hum Genet"},{"key":"4118_CR19","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1136\/jmedgenet-2012-101191","volume":"49","author":"FS Hilbers","year":"2012","unstructured":"Hilbers FS, Wijnen JT, Hoogerbrugge N, Oosterwijk JC, Collee MJ, Peterlongo P, Radice P, Manoukian S, Feroce I, Capra F, Couch FJ, Wang X, Guidugli L, Offit K, Shah S, Campbell IG, Thompson ER, James PA, Trainer AH, Gracia J, Benitez J, van Asperen CJ, Devilee P: Rare variants in XRCC2 as breast cancer susceptibility alleles. J Med Genet. 2012, 49: 618-620. 10.1136\/jmedgenet-2012-101191.","journal-title":"J Med Genet"},{"key":"4118_CR20","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1007\/s10549-011-1539-6","volume":"129","author":"J Johnson","year":"2011","unstructured":"Johnson J, Healey S, Khanna KK, Chenevix-Trench G, kConFab: Mutation analysis of RAD51L1 (RAD51B\/REC2) in multiple-case, non-BRCA1\/2 breast cancer families. Breast Cancer Res Treat. 2011, 129: 255-263. 10.1007\/s10549-011-1539-6.","journal-title":"Breast Cancer Res Treat"},{"key":"4118_CR21","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1002\/humu.21414","volume":"32","author":"V Caux-Moncoutier","year":"2011","unstructured":"Caux-Moncoutier V, Cast\u00e9ra L, Tirapo C, Michaux D, R\u00e9mon MA, Laug\u00e9 A, Rouleau E, De Pauw A, Buecher B, Gauthier-Villars M, Viovy JL, Stoppa-Lyonnet D, Houdayer C: EMMA, a cost- and time-effective diagnostic method for simultaneous detection of point mutations and large-scale genomic rearrangements: application to BRCA1 and BRCA2 in 1,525 patients. Hum Mutat. 2011, 32: 325-334. 10.1002\/humu.21414.","journal-title":"Hum Mutat"},{"key":"4118_CR22","unstructured":"Align-GVGD. http:\/\/agvgd.iarc.fr\/agvgd_input.php ,"},{"key":"4118_CR23","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1136\/jmg.2005.033878","volume":"43","author":"SV Tavtigian","year":"2006","unstructured":"Tavtigian SV, Deffenbaugh AM, Yin L, Judkins T, Scholl T, Samollow PB, de Silva D, Zharkikh A, Thomas A: Comprehensive statistical study of 452 BRCA1 missense substitutions with classification of eight recurrent substitutions as neutral. J Med Genet. 2006, 43: 295-305.","journal-title":"J Med Genet"},{"key":"4118_CR24","unstructured":"SIFT. http:\/\/sift.jcvi.org\/ ,"},{"key":"4118_CR25","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1038\/nprot.2009.86","volume":"4","author":"P Kumar","year":"2009","unstructured":"Kumar P, Henikoff S, Ng PC: Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm. Nat Protoc. 2009, 4: 1073-1081. 10.1038\/nprot.2009.86.","journal-title":"Nat Protoc"},{"key":"4118_CR26","unstructured":"Polyphen-2. http:\/\/genetics.bwh.harvard.edu\/pph2\/ ,"},{"key":"4118_CR27","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1038\/nmeth0410-248","volume":"7","author":"IA Adzhubei","year":"2010","unstructured":"Adzhubei IA, Schmidt S, Peshkin L, Ramensky VE, Gerasimova A, Bork P, Kondrashov AS, Sunyaev SR: A method and server for predicting damaging missense mutations. Nat Methods. 2010, 7: 248-249. 10.1038\/nmeth0410-248.","journal-title":"Nat Methods"},{"key":"4118_CR28","unstructured":"Exome Variant Server. http:\/\/evs.gs.washington.edu\/EVS\/ ,"},{"key":"4118_CR29","unstructured":"1000 Genomes. http:\/\/www.1000genomes.org\/ ,"},{"key":"4118_CR30","doi-asserted-by":"publisher","first-page":"1228","DOI":"10.1002\/humu.22101","volume":"33","author":"C Houdayer","year":"2012","unstructured":"Houdayer C, Caux-Moncoutier V, Krieger S, Barrois M, Bonnet F, Bourdon V, Bronner M, Buisson M, Coulet F, Gaildrat P, Lefol C, L\u00e9one M, Mazoyer S, Muller D, Remenieras A, R\u00e9villion F, Rouleau E, Sokolowska J, Vert JP, Lidereau R, Soubrier F, Sobol H, Sevenet N, Bressac-de Paillerets B, Hardouin A, Tosi M, Sinilnikova OM, Stoppa-Lyonnet D: Guidelines for splicing analysis in molecular diagnosis derived from a set of 327 combined in silico\/in vitro studies on BRCA1 and BRCA2 variants. Hum Mutat. 2012, 33: 1228-1238. 10.1002\/humu.22101.","journal-title":"Hum Mutat"},{"key":"4118_CR31","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/0165-4608(88)90305-6","volume":"32","author":"S Heim","year":"1988","unstructured":"Heim S, Nilbert M, Vanni R, Floderus UM, Mandahl N, Liedgren S, Lecca U, Mitelman F: A specific translocation, t(12;14)(q14-15;q23-24), characterizes a subgroup of uterine leiomyomas. Cancer Genet Cytogenet. 1988, 32: 13-17. 10.1016\/0165-4608(88)90305-6.","journal-title":"Cancer Genet Cytogenet"},{"key":"4118_CR32","first-page":"19","volume":"59","author":"EF Schoenmakers","year":"1999","unstructured":"Schoenmakers EF, Huysmans C, van de Ven WJ: Allelic knockout of novel splice variants of human recombination repair gene RAD51B in t(12;14) uterine leiomyomas. Cancer Res. 1999, 59: 19-23.","journal-title":"Cancer Res"},{"key":"4118_CR33","doi-asserted-by":"publisher","first-page":"6018","DOI":"10.1158\/0008-5472.CAN-05-2803","volume":"66","author":"O Date","year":"2006","unstructured":"Date O, Katsura M, Ishida M, Yoshihara T, Kinomura A, Sueda T, Miyagawa K: Haploinsufficiency of RAD51B causes centrosome fragmentation and aneuploidy in human cells. Cancer Res. 2006, 66: 6018-6024. 10.1158\/0008-5472.CAN-05-2803.","journal-title":"Cancer Res"},{"key":"4118_CR34","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1038\/ng.353","volume":"41","author":"G Thomas","year":"2009","unstructured":"Thomas G, Jacobs KB, Kraft P, Yeager M, Wacholder S, Cox DG, Hankinson SE, Hutchinson A, Wang Z, Yu K, Chatterjee N, Garcia-Closas M, Gonzalez-Bosquet J, Prokunina-Olsson L, Orr N, Willett WC, Colditz GA, Ziegler RG, Berg CD, Buys SS, McCarty CA, Feigelson HS, Calle EE, Thun MJ, Diver R, Prentice R, Jackson R, Kooperberg C, Chlebowski R, Lissowska J, et al: A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat Genet. 2009, 41: 579-584. 10.1038\/ng.353.","journal-title":"Nat Genet"},{"key":"4118_CR35","doi-asserted-by":"publisher","first-page":"1182","DOI":"10.1038\/ng.2417","volume":"44","author":"N Orr","year":"2012","unstructured":"Orr N, Lemnrau A, Cooke R, Fletcher O, Tomczyk K, Jones M, Johnson N, Lord CJ, Mitsopoulos C, Zvelebil M, McDade SS, Buck G, Blancher C, Trainer AH, James PA, Bojesen SE, Bokmand S, Nevanlinna H, Mattson J, Friedman E, Laitman Y, Palli D, Masala G, Zanna I, Ottini L, Giannini G, Hollestelle A, Ouweland AM, Novakovi\u0107 S, Krajc M, KConFab Consortium, et al: Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk. Nat Genet. 2012, 44: 1182-1184. 10.1038\/ng.2417.","journal-title":"Nat Genet"},{"key":"4118_CR36","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1056\/NEJMoa032909","volume":"351","author":"TM Zucchero","year":"2004","unstructured":"Zucchero TM, Cooper ME, Maher BS, Daack-Hirsch S, Nepomuceno B, Ribeiro L, Caprau D, Christensen K, Suzuki Y, Machida J, Natsume N, Yoshiura K, Vieira AR, Orioli IM, Castilla EE, Moreno L, Arcos-Burgos M, Lidral AC, Field LL, Liu YE, Ray A, Goldstein TH, Schultz RE, Shi M, Johnson MK, Kondo S, Schutte BC, Marazita ML, Murray JC: Interferon regulatory factor 6 (IRF6) gene variants and the risk of isolated cleft lip or palate. N Engl J Med. 2004, 351: 769-780. 10.1056\/NEJMoa032909.","journal-title":"N Engl J Med"},{"key":"4118_CR37","doi-asserted-by":"publisher","first-page":"e1000294","DOI":"10.1371\/journal.pbio.1000294","volume":"8","author":"SP Dickson","year":"2010","unstructured":"Dickson SP, Wang K, Krantz I, Hakonarson H, Goldstein DB: Rare variants create synthetic genome-wide associations. PLoS Biol. 2010, 8: e1000294-10.1371\/journal.pbio.1000294.","journal-title":"PLoS Biol"},{"key":"4118_CR38","unstructured":"dbSNP. http:\/\/www.ncbi.nlm.nih.gov\/SNP\/ ,"},{"key":"4118_CR39","doi-asserted-by":"publisher","first-page":"5125","DOI":"10.1007\/s11033-011-1308-y","volume":"39","author":"XF He","year":"2012","unstructured":"He XF, Wei W, Su J, Yang ZX, Liu Y, Zhang Y, Ding DP, Wang W: Association between the XRCC3 polymorphisms and breast cancer risk: meta-analysis based on case\u2013control studies. Mol Biol Rep. 2012, 39: 5125-5134. 10.1007\/s11033-011-1308-y.","journal-title":"Mol Biol Rep"},{"key":"4118_CR40","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1002\/humu.21625","volume":"33","author":"ER Thompson","year":"2012","unstructured":"Thompson ER, Boyle SE, Johnson J, Ryland GL, Sawyer S, Choong DY, Chenevix-Trench G, Trainer AH, Lindeman GJ, Mitchell G, James PA, Campbell IG, kConFab: Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients. Hum Mutat. 2012, 33: 95-99. 10.1002\/humu.21625.","journal-title":"Hum Mutat"},{"key":"4118_CR41","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1007\/s10549-011-1543-x","volume":"129","author":"A Romero","year":"2011","unstructured":"Romero A, P\u00e9rez-Segura P, Tosar A, Garc\u00eda-Saenz JA, D\u00edaz-Rubio E, Cald\u00e9s T, de la Hoya M: A HRM-based screening method detects RAD51C germ-line deleterious mutations in Spanish breast and ovarian cancer families. Breast Cancer Res Treat. 2011, 129: 939-946. 10.1007\/s10549-011-1543-x.","journal-title":"Breast Cancer Res Treat"},{"key":"4118_CR42","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1038\/ng.2224","volume":"44","author":"C Loveday","year":"2012","unstructured":"Loveday C, Turnbull C, Ruark E, Xicola RM, Ramsay E, Hughes D, Warren-Perry M, Snape K, Eccles D, Evans DG, Gore M, Renwick A, Seal S, Antoniou AC, Rahman N, Breast Cancer Susceptibility Collaboration (UK): Germline RAD51C mutations confer susceptibility to ovarian cancer. Nat Genet. 2012, 44: 475-476. 10.1038\/ng.2224. author reply 476","journal-title":"Nat Genet"}],"container-title":["BMC Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2407-13-484.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2407-13-484\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2407-13-484","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,7,12]],"date-time":"2016-07-12T16:06:55Z","timestamp":1468339615000},"score":1,"resource":{"primary":{"URL":"http:\/\/bmccancer.biomedcentral.com\/articles\/10.1186\/1471-2407-13-484"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,19]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["4118"],"URL":"https:\/\/doi.org\/10.1186\/1471-2407-13-484","relation":{},"ISSN":["1471-2407"],"issn-type":[{"value":"1471-2407","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,19]]},"article-number":"484"}}