{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:50:20Z","timestamp":1788310220268,"version":"build-2803163510"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2014,1,10]],"date-time":"2014-01-10T00:00:00Z","timestamp":1389312000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Cancer"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1186\/1471-2407-14-14","type":"journal-article","created":{"date-parts":[[2014,1,10]],"date-time":"2014-01-10T20:01:42Z","timestamp":1389384102000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Remodeling of the pulmonary artery induced by metastatic gastric carcinoma: a histopathological analysis of 51 autopsy cases"],"prefix":"10.1186","volume":"14","author":[{"given":"Takao","family":"Ishiwatari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoichiro","family":"Okubo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naobumi","family":"Tochigi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megumi","family":"Wakayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuo","family":"Nemoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junko","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minoru","family":"Shinozaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoko","family":"Aki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Sasai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiro","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruo","family":"Nakayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazutoshi","family":"Shibuya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,1,10]]},"reference":[{"key":"5200_CR1","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1007\/978-3-642-31629-6_17","volume":"196","author":"WB Robb","year":"2012","unstructured":"Robb WB, Mariette C: Predicting the response to chemotherapy in gastric adenocarcinoma: who benefits from neoadjuvant chemotherapy?. Recent Results Cancer Res. 2012, 196: 241-268. 10.1007\/978-3-642-31629-6_17.","journal-title":"Recent Results Cancer Res"},{"issue":"127","key":"5200_CR2","first-page":"2893","volume":"2010","author":"J Ferlay","year":"2008","unstructured":"Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM: Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2008, 2010 (127): 2893-2917.","journal-title":"Int J Cancer"},{"key":"5200_CR3","first-page":"249","volume":"14","author":"L Herszenyi","year":"2010","unstructured":"Herszenyi L, Tulassay Z: Epidemiology of gastrointestinal and liver tumors. Eur Rev Med Pharmacol Sci. 2010, 14: 249-258.","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"5200_CR4","doi-asserted-by":"publisher","first-page":"e79137","DOI":"10.1371\/journal.pone.0079137","volume":"8","author":"S Yu","year":"2013","unstructured":"Yu S, Yu Y, Zhao N, Cui J, Li W, Liu T: c-Met as a prognostic marker in gastric cancer: a systematic review and meta-analysis. PLoS One. 2013, 8: e79137-10.1371\/journal.pone.0079137.","journal-title":"PLoS One"},{"key":"5200_CR5","doi-asserted-by":"publisher","first-page":"4131","DOI":"10.3748\/wjg.v11.i27.4131","volume":"11","author":"J Shang","year":"2005","unstructured":"Shang J, Pena AS: Multidisciplinary approach to understand the pathogenesis of gastric cancer. World J Gastroenterol. 2005, 11: 4131-4139.","journal-title":"World J Gastroenterol"},{"key":"5200_CR6","first-page":"1133","volume":"69","author":"JC Layke","year":"2004","unstructured":"Layke JC, Lopez PP: Gastric cancer: diagnosis and treatment options. Am Fam Physician. 2004, 69: 1133-1140.","journal-title":"Am Fam Physician"},{"key":"5200_CR7","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1097\/01.sla.0000149300.28588.23","volume":"241","author":"BJ Dicken","year":"2005","unstructured":"Dicken BJ, Bigam DL, Cass C, Mackey JR, Joy AA, Hamilton SM: Gastric adenocarcinoma: review and considerations for future directions. Ann Surg. 2005, 241: 27-39.","journal-title":"Ann Surg"},{"key":"5200_CR8","doi-asserted-by":"publisher","first-page":"W152","DOI":"10.2214\/AJR.11.6407","volume":"198","author":"A Khashper","year":"2012","unstructured":"Khashper A, Discepola F, Kosiuk J, Qanadli SD, Mesurolle B: Nonthrombotic pulmonary embolism. AJR Am J Roentgenol. 2012, 198: W152-W159.","journal-title":"AJR Am J Roentgenol"},{"key":"5200_CR9","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/1746-1596-6-27","volume":"6","author":"Y Okubo","year":"2011","unstructured":"Okubo Y, Wakayama M, Kitahara K, Nemoto T, Yokose T, Abe F, Hiruta N, Sasai D, Shinozaki M, Nakayama H, Ishiwatari T, Shibuya K: Pulmonary tumor thrombotic microangiopathy induced by gastric carcinoma: morphometric and immunohistochemical analysis of six autopsy cases. Diagn Pathol. 2011, 6: 27-10.1186\/1746-1596-6-27.","journal-title":"Diagn Pathol"},{"key":"5200_CR10","doi-asserted-by":"publisher","first-page":"1317","DOI":"10.2169\/internalmedicine.52.9472","volume":"52","author":"H Uruga","year":"2013","unstructured":"Uruga H, Fujii T, Kurosaki A, Hanada S, Takaya H, Miyamoto A, Morokawa N, Homma S, Kishi K: Pulmonary tumor thrombotic microangiopathy: a clinical analysis of 30 autopsy cases. Intern Med. 2013, 52: 1317-1323. 10.2169\/internalmedicine.52.9472.","journal-title":"Intern Med"},{"key":"5200_CR11","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1002\/1097-0142(19900801)66:3<587::AID-CNCR2820660330>3.0.CO;2-J","volume":"66","author":"A von Herbay","year":"1990","unstructured":"von Herbay A, Illes A, Waldherr R, Otto HF: Pulmonary tumor thrombotic microangiopathy with pulmonary hypertension. Cancer. 1990, 66: 587-592. 10.1002\/1097-0142(19900801)66:3<587::AID-CNCR2820660330>3.0.CO;2-J.","journal-title":"Cancer"},{"key":"5200_CR12","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1016\/j.prp.2010.05.002","volume":"206","author":"K Chinen","year":"2010","unstructured":"Chinen K, Tokuda Y, Fujiwara M, Fujioka Y: Pulmonary tumor thrombotic microangiopathy in patients with gastric carcinoma: an analysis of 6 autopsy cases and review of the literature. Pathol Res Pract. 2010, 206: 682-689. 10.1016\/j.prp.2010.05.002.","journal-title":"Pathol Res Pract"},{"key":"5200_CR13","doi-asserted-by":"publisher","first-page":"212","DOI":"10.4103\/2045-8932.83453","volume":"1","author":"Z Wang","year":"2011","unstructured":"Wang Z, Chesler NC: Pulmonary vascular wall stiffness: an important contributor to the increased right ventricular afterload with pulmonary hypertension. Pulm Circ. 2011, 1: 212-223. 10.4103\/2045-8932.83453.","journal-title":"Pulm Circ"},{"key":"5200_CR14","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1186\/1465-9921-13-103","volume":"13","author":"K Shimodaira","year":"2012","unstructured":"Shimodaira K, Okubo Y, Ochiai E, Nakayama H, Katano H, Wakayama M, Shinozaki M, Ishiwatari T, Sasai D, Tochigi N, Nemoto T, Saji T, Kamei K, Shibuya K: Gene expression analysis of a murine model with pulmonary vascular remodeling compared to end-stage IPAH lungs. Respir Res. 2012, 13: 103-10.1186\/1465-9921-13-103.","journal-title":"Respir Res"},{"key":"5200_CR15","doi-asserted-by":"publisher","first-page":"S43","DOI":"10.1016\/j.jacc.2009.04.012","volume":"54","author":"G Simonneau","year":"2009","unstructured":"Simonneau G, Robbins IM, Beghetti M, Channick RN, Delcroix M, Denton CP, Elliott CG, Gaine SP, Gladwin MT, Jing ZC, Krowka MJ, Langleben D, Nakanishi N, Souza R: Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol. 2009, 54: S43-S54. 10.1016\/j.jacc.2009.04.012.","journal-title":"J Am Coll Cardiol"},{"key":"5200_CR16","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1056\/NEJM199608293350901","volume":"335","author":"L Abenhaim","year":"1996","unstructured":"Abenhaim L, Moride Y, Brenot F, Rich S, Benichou J, Kurz X, Higenbottam T, Oakley C, Wouters E, Aubier M, Simonneau G, Begaud B: Appetite-suppressant drugs and the risk of primary pulmonary hypertension. International primary pulmonary hypertension study group. N Engl J Med. 1996, 335: 609-616. 10.1056\/NEJM199608293350901.","journal-title":"N Engl J Med"},{"key":"5200_CR17","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1016\/j.ahj.2006.02.020","volume":"152","author":"AM Walker","year":"2006","unstructured":"Walker AM, Langleben D, Korelitz JJ, Rich S, Rubin LJ, Strom BL, Gonin R, Keast S, Badesch D, Barst RJ, Bourge RC, Channick R, Frost A, Gaine S, McGoon M, McLaughlin V, Murali S, Oudiz RJ, Robbins IM, Tapson V, Abenhaim L, Constantine G: Temporal trends and drug exposures in pulmonary hypertension: an american experience. Am Heart J. 2006, 152: 521-526. 10.1016\/j.ahj.2006.02.020.","journal-title":"Am Heart J"},{"key":"5200_CR18","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1161\/01.CIR.18.4.533","volume":"18","author":"D Heath","year":"1958","unstructured":"Heath D, Edwards JE: The pathology of hypertensive pulmonary vascular disease; a description of six grades of structural changes in the pulmonary arteries with special reference to congenital cardiac septal defects. Circulation. 1958, 18: 533-547. 10.1161\/01.CIR.18.4.533.","journal-title":"Circulation"},{"key":"5200_CR19","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/apm.1965.64.1.31","volume":"64","author":"P Lauren","year":"1965","unstructured":"Lauren P: The Two histological main types of gastric carcinoma: diffuse and So-called intestinal-type carcinoma. An attempt at a histo-clinical classification. Acta Pathol Microbiol Scand. 1965, 64: 31-49.","journal-title":"Acta Pathol Microbiol Scand"},{"key":"5200_CR20","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1001\/archsurg.2008.502","volume":"144","author":"JY An","year":"2009","unstructured":"An JY, Ha TK, Noh JH, Sohn TS, Kim S: Proposal to subclassify stage IV gastric cancer into IVA, IVB, and IVM. Arch Surg. 2009, 144: 38-45. 10.1001\/archsurg.2008.502. discussion 45","journal-title":"Arch Surg"},{"key":"5200_CR21","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1186\/1471-2407-12-346","volume":"12","author":"H Ito","year":"2012","unstructured":"Ito H, Inoue H, Sando N, Kimura S, Gohda K, Sato J, Murakami K, Ito S, Odaka N, Satodate H, Kudo SE: Prognostic impact of detecting viable circulating tumour cells in gastric cancer patients using a telomerase-specific viral agent: a prospective study. BMC Cancer. 2012, 12: 346-10.1186\/1471-2407-12-346.","journal-title":"BMC Cancer"},{"key":"5200_CR22","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1055\/s-0029-1233307","volume":"30","author":"RM Tuder","year":"2009","unstructured":"Tuder RM: Pathology of pulmonary arterial hypertension. Semin Respir Crit Care Med. 2009, 30: 376-385. 10.1055\/s-0029-1233307.","journal-title":"Semin Respir Crit Care Med"},{"key":"5200_CR23","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1242\/dmm.003616","volume":"3","author":"AL Firth","year":"2010","unstructured":"Firth AL, Mandel J, Yuan JX: Idiopathic pulmonary arterial hypertension. Dis Model Mech. 2010, 3: 268-273. 10.1242\/dmm.003616.","journal-title":"Dis Model Mech"},{"key":"5200_CR24","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1111\/j.1440-1827.2007.02111.x","volume":"57","author":"N Sakashita","year":"2007","unstructured":"Sakashita N, Yokose C, Fujii K, Matsumoto M, Ohnishi K, Takeya M: Pulmonary tumor thrombotic microangiopathy resulting from metastatic signet ring cell carcinoma of the stomach. Pathol Int. 2007, 57: 383-387. 10.1111\/j.1440-1827.2007.02111.x.","journal-title":"Pathol Int"}],"container-title":["BMC Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2407-14-14.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2407-14-14\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2407-14-14","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2407-14-14.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T10:10:00Z","timestamp":1630577400000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmccancer.biomedcentral.com\/articles\/10.1186\/1471-2407-14-14"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,10]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["5200"],"URL":"https:\/\/doi.org\/10.1186\/1471-2407-14-14","relation":{},"ISSN":["1471-2407"],"issn-type":[{"value":"1471-2407","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,10]]},"assertion":[{"value":"25 September 2013","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 January 2014","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 January 2014","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"14"}}