{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T04:06:14Z","timestamp":1767585974910},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2005,8,23]],"date-time":"2005-08-23T00:00:00Z","timestamp":1124755200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Cancer"],"published-print":{"date-parts":[[2005,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Post-transplant lymphoproliferative disorder (PTLD) is a complication of solid organ and allogeneic hematopoietic stem cell transplantation (HSCT); following autologous HSCT only rare cases of PTLD have been reported.<\/jats:p>\n            <jats:p>Here, a case of Hodgkin's disease (HD), as unusual presentation of PTLD after autologous HSCT for malignant glioma is described.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Case presentation<\/jats:title>\n            <jats:p>60-years old man affected by cerebral anaplastic astrocytoma underwent subtotal neurosurgical excision and subsequent high-dose chemotherapy followed by autologous HSCT. During the post HSCT course, cranial irradiation and corticosteroids were administered as completion of therapeutic program.<\/jats:p>\n            <jats:p>At day +105 after HSCT, the patient developed HD, nodular sclerosis type, with polymorphic HD-like skin infiltration.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>The clinical and pathological findings were consistent with the diagnosis of PTLD.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1471-2407-5-109","type":"journal-article","created":{"date-parts":[[2005,8,24]],"date-time":"2005-08-24T18:13:57Z","timestamp":1124907237000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Hodgkin's disease as unusual presentation of post-transplant lymphoproliferative disorder after autologous hematopoietic cell transplantation for malignant glioma"],"prefix":"10.1186","volume":"5","author":[{"given":"Alberto","family":"Zambelli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Lilleri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fausto","family":"Baldanti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Scelsi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Villani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gian Antonio","family":"Da Prada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2005,8,23]]},"reference":[{"issue":"5 Suppl 14","key":"297_CR1","first-page":"21","volume":"26","author":"LJ Swinnen","year":"1999","unstructured":"Swinnen LJ: Overview of posttransplant B-cell lymphoproliferative disorders. Semin Oncol. 1999, 26 (5 Suppl 14): 21-25.","journal-title":"Semin Oncol"},{"issue":"6","key":"297_CR2","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1182\/blood.V91.6.1833","volume":"91","author":"J Deeg","year":"1998","unstructured":"Deeg J, Socie G: Malignancies after hematopoietic stem cell transplantation: many question, some answers. Blood. 1998, 91 (6): 1833-44.","journal-title":"Blood"},{"issue":"2","key":"297_CR3","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1128\/JCM.38.2.613-619.2000","volume":"38","author":"F Baldanti","year":"2000","unstructured":"Baldanti F, Grossi P, Furione M, Simoncini L, Sarasini A, Comoli P, Maccario R, Fiocchi R, Gerna G: High levels of Epstein-Barr virus DNA in blood of solid-organ transplant recipients and their value in predicting posttransplant lymphoproliferative disorders. J Clin Microbiol. 2000, 38 (2): 613-9.","journal-title":"J Clin Microbiol"},{"issue":"1","key":"297_CR4","first-page":"8","volume":"14","author":"NL Harris","year":"1997","unstructured":"Harris NL, Ferry JA, Swerdlow SH: Posttransplant lymphoproliferative disorders: summury of Society for Hematopathology Workshop. Semin Diagn Pathol. 1997, 14 (1): 8-14.","journal-title":"Semin Diagn Pathol"},{"issue":"10","key":"297_CR5","doi-asserted-by":"crossref","first-page":"3122","DOI":"10.1200\/JCO.1999.17.10.3122","volume":"17","author":"PA Rowlings","year":"1999","unstructured":"Rowlings PA, Curtis RE, Passweg JR, Deeg HJ, Socie G, Travis LB, Kingma DW, Jaffe ES, Sobocinski KA, Horowitz MM: Increased incidence of Hodgkin's disease after allogeneic bone marrow transplantation. 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Br J Haematol. 1997, 98 (2): 485-7. 10.1046\/j.1365-2141.1997.2153034.x.","journal-title":"Br J Haematol"},{"issue":"12","key":"297_CR10","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1038\/sj.bmt.1701258","volume":"21","author":"RJ Hauke","year":"1998","unstructured":"Hauke RJ, Greiner TC, Smir BN, Vose JM, Tarantolo SR, Bashir RM, Bierman PJ: Epstein-Barr virus-associated lymphoproliferative disorder after autologous bone marrow transplantation: report of two cases. Bone Marrow Transplant. 1998, 21 (12): 1271-4. 10.1038\/sj.bmt.1701258.","journal-title":"Bone Marrow Transplant"},{"issue":"1\u20132","key":"297_CR11","doi-asserted-by":"publisher","first-page":"195","DOI":"10.3109\/10428190009053554","volume":"39","author":"CA Lohrisch","year":"2000","unstructured":"Lohrisch CA, Nevill TJ, Barnett MJ, Hogge DE, Connors JM, Keown PA, Gascoyne RD: Development of a biologically distinct EBV-related lymphoproliferative disorder following autologous bone marrow transplantation for an EBV-negative post-renal allograft Burkitt's lymphoma. Leuk Lymphoma. 2000, 39 (1\u20132): 195-201.","journal-title":"Leuk Lymphoma"},{"issue":"3","key":"297_CR12","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1038\/sj.bmt.1701335","volume":"22","author":"AJ Peniket","year":"1998","unstructured":"Peniket AJ, Perry AR, Williams CD, MacMillan A, Watts MJ, Isaacson PG, Goldstone AH, Linch DC: A case of EBV-associated lymphoproliferative disease following high-dose therapy and CD34-purified autologous peripheral blood progenitor cell transplantation. Bone Marrow Transplant. 1998, 22 (3): 307-9. 10.1038\/sj.bmt.1701335.","journal-title":"Bone Marrow Transplant"},{"issue":"12","key":"297_CR13","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1038\/sj.bmt.1702721","volume":"26","author":"Y Yufu","year":"2000","unstructured":"Yufu Y, Kimura M, Kawano R, Noguchi Y, Takatsuki H, Uike N, Ohshima K: EBV associated T cell lymphoproliferative disorder following autologous blood stem cell transplantation for relapsed Hodgkin's disease. Bone Marrow Transplant. 2000, 26 (12): 1339-41. 10.1038\/sj.bmt.1702721.","journal-title":"Bone Marrow Transplant"},{"issue":"5","key":"297_CR14","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1038\/sj.bmt.1703603","volume":"30","author":"D Jenkins","year":"2002","unstructured":"Jenkins D, Difrancesco L, Chaudhry A, Morris D, Gluks S, Jones A, Woodman R, Brown CB, Russel J, Stewart DA: Successful traetment of post-transplantation lymphoproliferative disorder in autologous blood stem cell transplant recipients. Bone Marrow Transplant. 2002, 30 (5): 321-6. 10.1038\/sj.bmt.1703603.","journal-title":"Bone Marrow Transplant"}],"container-title":["BMC Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2407-5-109.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2407-5-109\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2407-5-109","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2407-5-109.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,31]],"date-time":"2021-08-31T22:06:00Z","timestamp":1630447560000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmccancer.biomedcentral.com\/articles\/10.1186\/1471-2407-5-109"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,8,23]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,12]]}},"alternative-id":["297"],"URL":"https:\/\/doi.org\/10.1186\/1471-2407-5-109","relation":{},"ISSN":["1471-2407"],"issn-type":[{"value":"1471-2407","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,8,23]]},"assertion":[{"value":"1 February 2005","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 August 2005","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 August 2005","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"109"}}