{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T03:30:30Z","timestamp":1648697430297},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2008,3,10]],"date-time":"2008-03-10T00:00:00Z","timestamp":1205107200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Cancer"],"published-print":{"date-parts":[[2008,12]]},"DOI":"10.1186\/1471-2407-8-71","type":"journal-article","created":{"date-parts":[[2008,3,11]],"date-time":"2008-03-11T07:15:48Z","timestamp":1205219748000},"source":"Crossref","is-referenced-by-count":5,"title":["Comprehensive analysis of NuMAvariation in breast cancer"],"prefix":"10.1186","volume":"8","author":[{"given":"Outi","family":"Kilpivaara","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matias","family":"Rantanen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anitta","family":"Tamminen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristiina","family":"Aittom\u00e4ki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carl","family":"Blomqvist","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heli","family":"Nevanlinna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,3,10]]},"reference":[{"key":"1009_CR1","doi-asserted-by":"publisher","first-page":"2004","DOI":"10.1073\/pnas.0409806102","volume":"102","author":"S Kammerer","year":"2005","unstructured":"Kammerer S, Roth RB, Hoyal CR, Reneland R, Marnellos G, Kiechle M, Schwarz-Boeger U, Griffiths LR, Ebner F, Rehbock J, Cantor CR, Nelson MR, Braun A: Association of the NuMA region on chromosome 11q13 with breast cancer susceptibility. Proc Natl Acad Sci USA. 2005, 102: 2004-2009. 10.1073\/pnas.0409806102.","journal-title":"Proc Natl Acad Sci USA"},{"issue":"11","key":"1009_CR2","doi-asserted-by":"crossref","first-page":"2447","DOI":"10.1002\/j.1460-2075.1995.tb07242.x","volume":"14","author":"J Harborth","year":"1995","unstructured":"Harborth J, Weber K, Osborn M: Epitope mapping and direct visualization of the parallel, in-register arrangement of the double-stranded coiled-coil in the NuMA protein. EMBO J. 1995, 14 (11): 2447-60.","journal-title":"EMBO J"},{"issue":"3","key":"1009_CR3","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1016\/S0092-8674(00)81365-3","volume":"87","author":"A Merdes","year":"1996","unstructured":"Merdes A, Ramyar K, Vechio JD, Cleveland DW: A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly. Cell. 1996, 87 (3): 447-58. 10.1016\/S0092-8674(00)81365-3.","journal-title":"Cell"},{"issue":"Pt 2","key":"1009_CR4","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1242\/jcs.108.2.621","volume":"108","author":"DA Compton","year":"1995","unstructured":"Compton DA, Luo C: Mutation of the predicted p34cdc2 phosphorylation sites in NuMA impair the assembly of the mitotic spindle and block mitosis. J Cell Sci. 1995, 108 (Pt 2): 621-633.","journal-title":"J Cell Sci"},{"key":"1009_CR5","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1006\/excr.1996.0171","volume":"225","author":"C Gueth-Hallonet","year":"1996","unstructured":"Gueth-Hallonet C, Weber K, Osborn M: NuMA: A bipartite nuclear location signal and other functional properties of the tail domain. Exp Cell Res. 1996, 225: 207-218. 10.1006\/excr.1996.0171.","journal-title":"Exp Cell Res"},{"issue":"Pt 6","key":"1009_CR6","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1242\/jcs.107.6.1389","volume":"107","author":"TK Tang","year":"1994","unstructured":"Tang TK, Tang CJ, Chao YJ, Wu CW: Nuclear mitotic apparatus protein (NuMA): Spindle association, nuclear targeting and differential subcellular localization of various NuMA isoforms. J Cell Sci. 1994, 107 (Pt 6): 1389-1402.","journal-title":"J Cell Sci"},{"key":"1009_CR7","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1083\/jcb.120.4.947","volume":"120","author":"DA Compton","year":"1993","unstructured":"Compton DA, Cleveland DW: NuMA is required for the proper completion of mitosis. J Cell Biol. 1993, 120: 947-957. 10.1083\/jcb.120.4.947.","journal-title":"J Cell Biol"},{"key":"1009_CR8","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1038\/ng0997-109","volume":"17","author":"RA Wells","year":"1997","unstructured":"Wells RA, Catzavelos C, Kamel-Reid S: Fusion of retinoic acid receptor alpha to NuMA, the nuclear mitotic apparatus protein, by a variant translocation in acute promyelocytic leukaemia. Nat Genet. 1997, 17: 109-113. 10.1038\/ng0997-109.","journal-title":"Nat Genet"},{"key":"1009_CR9","doi-asserted-by":"publisher","first-page":"31979","DOI":"10.1074\/jbc.M000994200","volume":"275","author":"J Harborth","year":"2000","unstructured":"Harborth J, Weber K, Osborn M: GAS41, a highly conserved protein in eukaryotic nuclei, binds to NuMA. J Biol Chem. 2000, 275: 31979-31985. 10.1074\/jbc.M000994200.","journal-title":"J Biol Chem"},{"key":"1009_CR10","doi-asserted-by":"publisher","first-page":"1817","DOI":"10.1093\/hmg\/6.11.1817","volume":"6","author":"U Fischer","year":"1997","unstructured":"Fischer U, Heckel D, Michel A, Janka M, Hulsebos T, Meese E: Cloning of a novel transcription factor-like gene amplified in human glioma including astrocytoma grade I. Hum Mol Genet. 1997, 6: 1817-1822. 10.1093\/hmg\/6.11.1817.","journal-title":"Hum Mol Genet"},{"key":"1009_CR11","doi-asserted-by":"publisher","first-page":"1529","DOI":"10.1093\/jnci\/92.18.1529","volume":"92","author":"K Syrjakoski","year":"2000","unstructured":"Syrjakoski K, Vahteristo P, Eerola H, Tamminen A, Kivinummi K, Sarantaus L, Holli K, Blomqvist C, Kallioniemi OP, Kainu T, Nevanlinna H: Population-based study of BRCA1 and BRCA2 mutations in 1035 unselected finnish breast cancer patients. J Natl Cancer Inst. 2000, 92: 1529-1531. 10.1093\/jnci\/92.18.1529.","journal-title":"J Natl Cancer Inst"},{"key":"1009_CR12","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1002\/ijc.20638","volume":"113","author":"O Kilpivaara","year":"2005","unstructured":"Kilpivaara O, Bartkova J, Eerola H, Syrjakoski K, Vahteristo P, Lukas J, Blomqvist C, Holli K, Heikkila P, Sauter G, Kallioniemi OP, Bartek J, Nevanlinna H: Correlation of CHEK2 protein expression and c.1100delC mutation status with tumor characteristics among unselected breast cancer patients. Int J Cancer. 2005, 113: 575-580. 10.1002\/ijc.20638.","journal-title":"Int J Cancer"},{"key":"1009_CR13","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1016\/S0959-8049(00)00093-9","volume":"36","author":"H Eerola","year":"2000","unstructured":"Eerola H, Blomqvist C, Pukkala E, Pyrhonen S, Nevanlinna H: Familial breast cancer in southern finland: How prevalent are breast cancer families and can we trust the family history reported by patients?. Eur J Cancer. 2000, 36: 1143-1148. 10.1016\/S0959-8049(00)00093-9.","journal-title":"Eur J Cancer"},{"key":"1009_CR14","doi-asserted-by":"publisher","first-page":"2309","DOI":"10.1093\/hmg\/6.13.2309","volume":"6","author":"P Vehmanen","year":"1997","unstructured":"Vehmanen P, Friedman LS, Eerola H, McClure M, Ward B, Sarantaus L, Kainu T, Syrjakoski K, Pyrhonen S, Kallioniemi OP, Muhonen T, Luce M, Frank TS, Nevanlinna H: Low proportion of BRCA1 and BRCA2 mutations in finnish breast cancer families: Evidence for additional susceptibility genes. Hum Mol Genet. 1997, 6: 2309-2315. 10.1093\/hmg\/6.13.2309.","journal-title":"Hum Mol Genet"},{"key":"1009_CR15","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1054\/bjoc.2000.1626","volume":"84","author":"P Vahteristo","year":"2001","unstructured":"Vahteristo P, Eerola H, Tamminen A, Blomqvist C, Nevanlinna H: A probability model for predicting BRCA1 and BRCA2 mutations in breast and breast-ovarian cancer families. Br J Cancer. 2001, 84: 704-708. 10.1054\/bjoc.2000.1626.","journal-title":"Br J Cancer"},{"key":"1009_CR16","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1086\/341943","volume":"71","author":"P Vahteristo","year":"2002","unstructured":"Vahteristo P, Bartkova J, Eerola H, Syrjakoski K, Ojala S, Kilpivaara O, Tamminen A, Kononen J, Aittomaki K, Heikkila P, Holli K, Blomqvist C, Bartek J, Kallioniemi OP, Nevanlinna H: A CHEK2 genetic variant contributing to a substantial fraction of familial breast cancer. Am J Hum Genet. 2002, 71: 432-438. 10.1086\/341943.","journal-title":"Am J Hum Genet"},{"key":"1009_CR17","unstructured":"SIFT. [ http:\/\/blocks.fhcrc.org\/sift\/SIFT.html ]"},{"key":"1009_CR18","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1101\/gr.212802","volume":"12","author":"PC Ng","year":"2002","unstructured":"Ng PC, Henikoff S: Accounting for human polymorphisms predicted to affect protein function. Genome Res. 2002, 12: 436-446. 10.1101\/gr.212802.","journal-title":"Genome Res"},{"key":"1009_CR19","unstructured":"PolyPhen. [ http:\/\/www.bork.embl-heidelberg.de\/PolyPhen\/ ]"},{"key":"1009_CR20","doi-asserted-by":"publisher","first-page":"3894","DOI":"10.1093\/nar\/gkf493","volume":"30","author":"V Ramensky","year":"2002","unstructured":"Ramensky V, Bork P, Sunyaev S: Human non-synonymous SNPs: Server and survey. Nucleic Acids Res. 2002, 30: 3894-3900. 10.1093\/nar\/gkf493.","journal-title":"Nucleic Acids Res"},{"key":"1009_CR21","unstructured":"PHASE Software for Haplotype Estimation. [ http:\/\/www.stat.washington.edu\/stephens\/software.html ]"},{"key":"1009_CR22","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1086\/319501","volume":"68","author":"M Stephens","year":"2001","unstructured":"Stephens M, Smith NJ, Donnelly P: A new statistical method for haplotype reconstruction from population data. Am J Hum Genet. 2001, 68: 978-989. 10.1086\/319501.","journal-title":"Am J Hum Genet"},{"key":"1009_CR23","doi-asserted-by":"publisher","first-page":"1162","DOI":"10.1086\/379378","volume":"73","author":"M Stephens","year":"2003","unstructured":"Stephens M, Donnelly P: A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet. 2003, 73: 1162-1169. 10.1086\/379378.","journal-title":"Am J Hum Genet"},{"issue":"3","key":"1009_CR24","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1038\/ng1981","volume":"39","author":"A Cox","year":"2007","unstructured":"Cox A, Dunning AM, Garcia-Closas M, Balasubramanian S, Reed MW, Pooley KA, Scollen S, Baynes C, Ponder BA, Chanock S, Lissowska J, Brinton L, Peplonska B, Southey MC, Hopper JL, McCredie MR, Giles GG, Fletcher O, Johnson N, dos Santos Silva I, Gibson L, Bojesen SE, Nordestgaard BG, Axelsson CK, Torres D, Hamann U, Justenhoven C, Brauch H, Chang-Claude J, Kropp S, Risch A, Wang-Gohrke S, Schurmann P, Bogdanova N, Dork T, Fagerholm R, Aaltonen K, Blomqvist C, Nevanlinna H, Seal S, Renwick A, Stratton MR, Rahman N, Sangrajrang S, Hughes D, Odefrey F, Brennan P, Spurdle AB, Chenevix-Trench G, Kathleen Cunningham Foundation Consortium for Research into Familial Breast Cancer, Beesley J, Mannermaa A, Hartikainen J, Kataja V, Kosma VM, Couch FJ, Olson JE, Goode EL, Broeks A, Schmidt MK, Hogervorst FB, Van't Veer LJ, Kang D, Yoo KY, Noh DY, Ahn SH, Wedren S, Hall P, Low YL, Liu J, Milne RL, Ribas G, Gonzalez-Neira A, Benitez J, Sigurdson AJ, Stredrick DL, Alexander BH, Struewing JP, Pharoah PD, Easton DF, Breast Cancer Association Consortium: A common coding variant in CASP8 is associated with breast cancer risk. Nat Genet. 2007, 39 (3): 352-358. 10.1038\/ng1981.","journal-title":"Nat Genet"}],"container-title":["BMC Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2407-8-71\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2407-8-71.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2407-8-71","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2407-8-71.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,5]],"date-time":"2021-09-05T16:40:54Z","timestamp":1630860054000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmccancer.biomedcentral.com\/articles\/10.1186\/1471-2407-8-71"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3,10]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["1009"],"URL":"https:\/\/doi.org\/10.1186\/1471-2407-8-71","relation":{},"ISSN":["1471-2407"],"issn-type":[{"value":"1471-2407","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,3,10]]},"article-number":"71"}}