{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T13:53:00Z","timestamp":1793109180948,"version":"4.5.0"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2009,6,18]],"date-time":"2009-06-18T00:00:00Z","timestamp":1245283200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Cancer"],"published-print":{"date-parts":[[2009,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Teratomas are the commonest germ cell tumours and are most frequently found in the testes and ovary. Extragonadal teratomas are rare and mainly occur in midline structures. Uterine teratomas are extremely rare with only a few previous case reports, usually involving mature teratomas of the uterine cervix.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Case Presentation<\/jats:title>\n            <jats:p>We report an 82-year-old lady presenting with post-menopausal bleeding. Initial investigations revealed a benign teratoma of the uterus which was removed. Her symptoms persisted and a recurrent, now malignant, teratoma of the uterine corpus was resected at hysterectomy. Six months after surgery she relapsed with para-aortic lymphadenopathy and was treated with a taxane, etoposide and cisplatin-containing chemotherapy regimen followed by retroperitoneal lymph node dissection.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>In this report we discuss the aetiology, diagnosis and management of uterine teratomas, and review previous case studies.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1471-2407-9-195","type":"journal-article","created":{"date-parts":[[2009,6,19]],"date-time":"2009-06-19T06:14:52Z","timestamp":1245392092000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Case report: Malignant teratoma of the uterine corpus"],"prefix":"10.1186","volume":"9","author":[{"given":"Thomas","family":"Newsom-Davis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Poulter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Gray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Ameen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iain","family":"Lindsay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyriakos","family":"Papanikolaou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Butler-Manuel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Christmas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Townsend","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Seckl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2009,6,18]]},"reference":[{"issue":"5","key":"1529_CR1","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1046\/j.1440-1827.2003.01468.x","volume":"53","author":"SC Lim","year":"2003","unstructured":"Lim SC, Kim YS, Lee YH, Lee MS, Lim JY: Mature teratoma of the uterine cervix with lymphoid hyperplasia. Pathol Int. 2003, 53 (5): 327-331. 10.1046\/j.1440-1827.2003.01468.x.","journal-title":"Pathol Int"},{"issue":"6","key":"1529_CR2","doi-asserted-by":"publisher","first-page":"1169","DOI":"10.1038\/sj.bjc.6601664","volume":"90","author":"IA McNeish","year":"2004","unstructured":"McNeish IA, Kanfer EJ, Haynes R, Giles C, Harland SJ, Driver D, Rustin GJ, Newlands ES, Seckl MJ: Paclitaxel-containing high-dose chemotherapy for relapsed or refractory testicular germ cell tumours. Br J Cancer. 2004, 90 (6): 1169-1175. 10.1038\/sj.bjc.6601664.","journal-title":"Br J Cancer"},{"issue":"9","key":"1529_CR3","doi-asserted-by":"publisher","first-page":"1578","DOI":"10.1093\/annonc\/mdn181","volume":"19","author":"J Wang","year":"2008","unstructured":"Wang J, Short D, Sebire NJ, Lindsay I, Newlands ES, Schmid P, Savage PM, Seckl MJ: Salvage chemotherapy of relapsed or high-risk gestational trophoblastic neoplasia (GTN) with paclitaxel\/cisplatin alternating with paclitaxel\/etoposide (TP\/TE). Ann Oncol. 2008, 19 (9): 1578-83. 10.1093\/annonc\/mdn181.","journal-title":"Ann Oncol"},{"issue":"4","key":"1529_CR4","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/j.anndiagpath.2006.03.019","volume":"11","author":"NK Panesar","year":"2007","unstructured":"Panesar NK, Sidhu JS: Uterine cervical teratoma with divergent neuroepithelial differentiation and development of an oligodendroglioma: report of a case and review of the literature. Ann Diagn Pathol. 2007, 11 (4): 293-296. 10.1016\/j.anndiagpath.2006.03.019.","journal-title":"Ann Diagn Pathol"},{"issue":"9","key":"1529_CR5","first-page":"936","volume":"77","author":"O Takahashi","year":"1998","unstructured":"Takahashi O, Shibata S, Hatazawa J, Takisawa J, Sato H, Ota H, Tanaka T: Mature cystic teratoma of the uterine corpus. Acta Obstet Gynecol Scand. 1998, 77 (9): 936-938.","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"1","key":"1529_CR6","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1016\/0090-8258(85)90240-9","volume":"21","author":"Y Ansah-Boateng","year":"1985","unstructured":"Ansah-Boateng Y, Wells M, Poole DR: Coexistent immature teratoma of the uterus and endometrial adenocarcinoma complicated by gliomatosis peritonei. Gynecol Oncol. 1985, 21 (1): 106-110. 10.1016\/0090-8258(85)90240-9.","journal-title":"Gynecol Oncol"},{"issue":"2 Pt 2","key":"1529_CR7","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1097\/01.AOG.0000262898.96160.16","volume":"110","author":"V Gomez-Lobo","year":"2007","unstructured":"Gomez-Lobo V, Burch W, Khanna PC: Nonpuerperal uterine inversion associated with an immature teratoma of the uterus in an adolescent. Obstet Gynecol. 2007, 110 (2 Pt 2): 491-493.","journal-title":"Obstet Gynecol"},{"issue":"3","key":"1529_CR8","doi-asserted-by":"publisher","first-page":"153","DOI":"10.2739\/kurumemedj.40.153","volume":"40","author":"S Iwanaga","year":"1993","unstructured":"Iwanaga S, Shimada A, Hasuo Y, Yoh S, Miyajima S, Nishimura H, Yakushiji M: Immature teratoma of the uterine fundus. Kurume Med J. 1993, 40 (3): 153-158.","journal-title":"Kurume Med J"},{"issue":"5","key":"1529_CR9","first-page":"686","volume":"40","author":"CW Newton 3rd","year":"1972","unstructured":"Newton CW, Abell MR: Iatrogenic fetal implants. Obstet Gynecol. 1972, 40 (5): 686-691.","journal-title":"Obstet Gynecol"},{"issue":"4","key":"1529_CR10","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1111\/j.1365-2559.1979.tb03015.x","volume":"3","author":"SP Tyagi","year":"1979","unstructured":"Tyagi SP, Saxena K, Rizvi R, Langley FA: Foetal remnants in the uterus and their relation to other uterine heterotopia. Histopathology. 1979, 3 (4): 339-345. 10.1111\/j.1365-2559.1979.tb03015.x.","journal-title":"Histopathology"},{"issue":"2","key":"1529_CR11","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1056\/NEJM197501092920202","volume":"292","author":"D Linder","year":"1975","unstructured":"Linder D, McCaw BK, Hecht F: Parthenogenic origin of benign ovarian teratomas. N Engl J Med. 1975, 292 (2): 63-66.","journal-title":"N Engl J Med"},{"issue":"4","key":"1529_CR12","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1002\/uog.3969","volume":"29","author":"A Papadia","year":"2007","unstructured":"Papadia A, Rutigliani M, Gerbaldo D, Fulcheri E, Ragni N: Mature cystic teratoma of the uterus presenting as an endometrial polyp. Ultrasound Obstet Gynecol. 2007, 29 (4): 477-478. 10.1002\/uog.3969.","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"1","key":"1529_CR13","doi-asserted-by":"publisher","first-page":"216","DOI":"10.2214\/ajr.185.1.01850216","volume":"185","author":"M Akai","year":"2005","unstructured":"Akai M, Isoda H, Sawada S, Matsuo I, Kanzaki H, Sakaida N, Okamura A, Kiyokawa T: A case of struma uteri. AJR Am J Roentgenol. 2005, 185 (1): 216-218.","journal-title":"AJR Am J Roentgenol"},{"issue":"1","key":"1529_CR14","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1111\/j.1525-1438.2007.00969.x","volume":"18","author":"DM Patterson","year":"2008","unstructured":"Patterson DM, Murugaesu N, Holden L, Seckl MJ, Rustin GJ: A review of the close surveillance policy for stage I female germ cell tumors of the ovary and other sites. Int J Gynecol Cancer. 2008, 18 (1): 43-50.","journal-title":"Int J Gynecol Cancer"}],"container-title":["BMC Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2407-9-195.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2407-9-195\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2407-9-195","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2407-9-195.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T02:11:32Z","timestamp":1630462292000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmccancer.biomedcentral.com\/articles\/10.1186\/1471-2407-9-195"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,6,18]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["1529"],"URL":"https:\/\/doi.org\/10.1186\/1471-2407-9-195","relation":{},"ISSN":["1471-2407"],"issn-type":[{"value":"1471-2407","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,6,18]]},"assertion":[{"value":"8 January 2009","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 June 2009","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 June 2009","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"195"}}