{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T02:21:48Z","timestamp":1783650108146,"version":"3.55.0"},"reference-count":6,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2013,7,10]],"date-time":"2013-07-10T00:00:00Z","timestamp":1373414400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Ophthalmol"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>We report two cases of unilateral upper eyelid swelling with multiple small lumps as an unusual complication of autogenous fat injection for cosmetic forehead augmentation.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Case presentation<\/jats:title>\n            <jats:p>Two female patients were referred to our clinic for unusual unilateral eyelid swelling, with multiple small lumps. The duration of symptoms differed in each case, but both patients had a history of autogenous fat injection for cosmetic forehead augmentation at a local plastic surgery clinic. The lumps were small (diameter 5 mm~10 mm), palpable, hard, and nonmobile, and were evaluated by magnetic resonance imaging (MRI). Lumps from the eyelids of two patients were excised under general anesthesia. All of the masses were located deeply and found near the superior orbital rim or lateral orbital rim. The lumps exhibited chronic inflammation with fibrosis. Some of the lumps showed foamy histiocytic aggregation and foreign body lipogranuloma, resulting from iatrogenic fat injection. After excision, all masses and swelling disappeared, and moderate ptotic eyelid or lagophthalmos of affected eyes also improved.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>To our knowledge, eyelid swelling with multiple lumps in the eyelid is a very rare complication of autogenous fat injection for cosmetic forehead augmentation. This report should be helpful for ophthalmic clinicians who encounter these unusual symptoms.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1471-2415-13-32","type":"journal-article","created":{"date-parts":[[2013,7,10]],"date-time":"2013-07-10T12:14:04Z","timestamp":1373458444000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Eyelid-associated complications after autogenous fat injection for cosmetic forehead augmentation"],"prefix":"10.1186","volume":"13","author":[{"given":"Ji-Sun","family":"Paik","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won-Kyung","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gyeong-Sin","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suk-Woo","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,7,10]]},"reference":[{"issue":"2","key":"328_CR1","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1055\/s-2004-861755","volume":"20","author":"T Cook","year":"2004","unstructured":"Cook T, Nakra T, Shorr N, Douglas RS: Facial recontouring with autogenous fat. Facial Plast Surg. 2004, 20 (2): 145-147. 10.1055\/s-2004-861755.","journal-title":"Facial Plast Surg"},{"issue":"5","key":"328_CR2","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1055\/s-0030-1265020","volume":"26","author":"CL Stallworth","year":"2010","unstructured":"Stallworth CL, Wang TD: Fat grafting of the midface. Facial Plast Surg. 2010, 26 (5): 369-375. 10.1055\/s-0030-1265020.","journal-title":"Facial Plast Surg"},{"issue":"5","key":"328_CR3","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1111\/j.1524-4725.2007.33116.x","volume":"33","author":"S Kranendonk","year":"2007","unstructured":"Kranendonk S, Obaqi S: Autologous fat transfer for periorbital rejuvenation: indications, technique, and complications. Dermatol Surg. 2007, 33 (5): 572-578. 10.1111\/j.1524-4725.2007.33116.x.","journal-title":"Dermatol Surg"},{"issue":"6","key":"328_CR4","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1097\/01.sap.0000248110.59452.49","volume":"58","author":"S Hu","year":"2007","unstructured":"Hu S, Zhang H, Feng Y, Yang Y, Han X, Han X, Han X, Zhong Y, Shi J: Introduction of an easy technique for purification and injection of autogenous free fat parcels in correcting of facial contour deformities. Ann Plast Surg. 2007, 58 (6): 602-607. 10.1097\/01.sap.0000248110.59452.49.","journal-title":"Ann Plast Surg"},{"issue":"5","key":"328_CR5","first-page":"777","volume":"119","author":"HV Danesh-Meyer","year":"2001","unstructured":"Danesh-Meyer HV, Savino PJ, Sergott RC: Case reports and small case series: ocular and cerebral facial injection of autologous fat. Arch Ophthalmol. 2001, 119 (5): 777-778.","journal-title":"Arch Ophthalmol"},{"issue":"2","key":"328_CR6","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/j.jvir.2010.10.023","volume":"22","author":"SJ Park","year":"2011","unstructured":"Park SJ, Woo SJ, Park KH, Hwang JM, Hwang GJ, Jung C, Kwon OK: Partial recovery after intraarterial pharmacomechanical thrombolysis in ophthalmic artery occlusion following nasal autologous fat injection. J Vasc Interv Radiol. 2011, 22 (2): 251-254. 10.1016\/j.jvir.2010.10.023.","journal-title":"J Vasc Interv Radiol"}],"container-title":["BMC Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2415-13-32.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2415-13-32\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2415-13-32","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2415-13-32.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T20:34:10Z","timestamp":1630528450000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcophthalmol.biomedcentral.com\/articles\/10.1186\/1471-2415-13-32"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,10]]},"references-count":6,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["328"],"URL":"https:\/\/doi.org\/10.1186\/1471-2415-13-32","relation":{},"ISSN":["1471-2415"],"issn-type":[{"value":"1471-2415","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,10]]},"assertion":[{"value":"12 October 2012","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 July 2013","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 July 2013","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"32"}}