{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T19:40:32Z","timestamp":1760298032280},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2008,11,13]],"date-time":"2008-11-13T00:00:00Z","timestamp":1226534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Ophthalmol"],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>The Early Treatment for Retinopathy of Prematurity study (ETROP), published in 2003, established new guidelines for treatment of retinopathy of prematurity (ROP) and demonstrated improved outcomes compared to previous guidelines. We examined outcomes before and after implementing the ETROP recommendations.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>A retrospective chart review was performed using records of infants who had laser ablations for ROP performed from January, 2000 through December, 2005. Data collected included date of birth; birth weight; estimated gestational age (EGA); grading of ROP; date of laser ablation; and outcome of laser surgery. Univariate association with threshold or prethreshold treatment (Pre-ETROP and Post-ETROP, respectively) were assessed using t-tests or Wilcoxon tests. Additional comparison between groups was performed using Fisher's exact tests.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>581 patients were examined before and 464 after December 2003. Of these, 29\/581 (5% \u2013 Pre-ETROP Group) and 53\/464 (11% \u2013 Post-ETROP Group) patients advanced to criteria requiring laser treatment respectively (P = 0.0001). The average estimated gestational age (EGA) at birth was 26.3 and 25.2 weeks, with an average birth weight of 888 and 707 grams for Pre and Post-ETROP Groups, respectively. Stage 5 retinal detachment (RD) developed in 10.3% of eyes in the Pre-ETROP Group and 1.9% of eyes in the Post-ETROP Group (P = 0.02).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>After the ETROP guidelines were implemented, there was a decrease from 10.3% to 1.9% of eyes developing Stage 5 retinal detachment, despite this group having a lower average EGA and lower average birth weight. These results underscore the importance of adoption of the Revised Indications.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1471-2415-8-23","type":"journal-article","created":{"date-parts":[[2008,12,18]],"date-time":"2008-12-18T19:15:18Z","timestamp":1229627718000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Outcome of retinopathy of prematurity patients following adoption of revised indications for treatment"],"prefix":"10.1186","volume":"8","author":[{"given":"Aaron M","family":"Alme","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael L","family":"Mulhern","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas W","family":"Hejkal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane L","family":"Meza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David D","family":"Ingvoldstad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eyal","family":"Margalit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,11,13]]},"reference":[{"key":"143_CR1","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/S0002-9394(42)92088-9","volume":"25","author":"TL Terry","year":"1942","unstructured":"Terry TL: Extreme prematurity and fibroblastic overgrowth of persistent vascular sheath behind each crystalline lens. I. Preliminary report. Am J Ophthalmol. 1942, 25: 203-4.","journal-title":"Am J Ophthalmol"},{"key":"143_CR2","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1016\/S0161-6420(91)32247-4","volume":"98","author":"J McNamara","year":"1991","unstructured":"McNamara J: Laser photocoagulation for stage 3+ retinopathy of prematurity. Ophthalmology. 1991, 98: 576-580.","journal-title":"Ophthalmology"},{"issue":"4","key":"143_CR3","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1097\/00004397-200110000-00013","volume":"41","author":"QD Nguyen","year":"2001","unstructured":"Nguyen QD: Recent Advances in Retinopathy of Prematurity. Int Ophthalmol Clin. 2001, 41 (4): 129-151. 10.1097\/00004397-200110000-00013.","journal-title":"Int Ophthalmol Clin"},{"key":"143_CR4","doi-asserted-by":"publisher","first-page":"906","DOI":"10.1001\/archopht.1987.01060070042025","volume":"105","author":"International Committee for the Classification of the Late Stages of Retinopathy of Prematurity","year":"1987","unstructured":"International Committee for the Classification of the Late Stages of Retinopathy of Prematurity: An international classification of retinopathy of prematurity. II. The classification of retinal detachment. Arch Ophthalmol. 1987, 105: 906-12.","journal-title":"Arch Ophthalmol"},{"key":"143_CR5","first-page":"471","volume":"106","author":"Committee for the Classification of Retinopathy of Prematurity","year":"1984","unstructured":"Committee for the Classification of Retinopathy of Prematurity: An international classification of retinopathy of prematurity. 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Ophthalmology. 1993, 100: 230-237.","journal-title":"Ophthalmology"},{"key":"143_CR8","doi-asserted-by":"publisher","first-page":"1684","DOI":"10.1001\/archopht.121.12.1684","volume":"121","author":"WV Good","year":"2003","unstructured":"Good WV: Revised Indications for the Treatment of Retinopathy of Prematurity. Results of the Early Treatment for Retinopathy of Prematurity Randomized Trial. Arch Ophthalmol. 2003, 121: 1684-1696. 10.1001\/archopht.121.12.1684.","journal-title":"Arch Ophthalmol"},{"key":"143_CR9","doi-asserted-by":"publisher","first-page":"1110","DOI":"10.1001\/archopht.119.8.1110","volume":"119","author":"Cryotherapy for Retinopathy of Prematurity Cooperative Group","year":"2001","unstructured":"Cryotherapy for Retinopathy of Prematurity Cooperative Group: Multicenter trial of cryotherapy for retinopathy of prematurity: ophthalmological outcomes at 10 years. Arch Ophthalmol. 2001, 119: 1110-33.","journal-title":"Arch Ophthalmol"},{"key":"143_CR10","doi-asserted-by":"publisher","first-page":"1697","DOI":"10.1001\/archopht.121.12.1697","volume":"121","author":"RJ Hardy","year":"2003","unstructured":"Hardy RJ, Palmer EA, Dobson V: Risk Analysis of Prethreshold Retinopathy of Prematurity. Archives of Ophthalmology. 2003, 121: 1697-1701. 10.1001\/archopht.121.12.1697.","journal-title":"Archives of Ophthalmology"},{"issue":"2","key":"143_CR11","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1016\/j.ajo.2004.12.106","volume":"140","author":"DK Coats","year":"2005","unstructured":"Coats DK: Involution of Retinopathy of Prematurity After Laser Treatment: Factors Associated With Development of Retinal Detachment. 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