{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T20:42:16Z","timestamp":1781642536753,"version":"3.54.5"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2005,5,21]],"date-time":"2005-05-21T00:00:00Z","timestamp":1116633600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Pediatr"],"published-print":{"date-parts":[[2005,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>To describe the presenting clinical features of coeliac disease in a single paediatric centre, and to determine if the presenting features vary with age.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>A review was conducted of children who had been referred with clinical suspicion of coeliac disease to the paediatric gastroenterology department of a tertiary paediatric hospital in Sydney, Australia. Coeliac disease was defined using standard histological criteria. Medical records were reviewed retrospectively.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Clinical data were available for 74 cases of proven coeliac disease. Only 9% of patients were less than 2 years of age at diagnosis. Pre-school children (age &lt;5 years) presented with different symptoms to school children (age \u2265 5 years). The most common presenting features in younger children were diarrhoea, irritability and weight loss. However, in older children, abdominal pain was the most common presenting feature.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>We found a significant difference in the clinical features of coeliac disease in pre-school compared to school age children.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1471-2431-5-11","type":"journal-article","created":{"date-parts":[[2005,5,21]],"date-time":"2005-05-21T06:14:35Z","timestamp":1116656075000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Age related clinical features of childhood Coeliac disease in Australia"],"prefix":"10.1186","volume":"5","author":[{"given":"Monique L","family":"Stone","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy D","family":"Bohane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kylie E","family":"Whitten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivienne H","family":"Tobias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew S","family":"Day","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2005,5,21]]},"reference":[{"key":"64_CR1","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1136\/gut.40.1.61","volume":"40","author":"GE K","year":"1997","unstructured":"K GE, Mearin ML, Franken HCM, Houwen RHJ, Hirasing RA, Vandenbrouche JP: Twenty Years of childhood coeliac disease in The Netherlands: a rapidly increasing incidence?. 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