{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T22:49:14Z","timestamp":1790808554740,"version":"4.1.0"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2007,6,11]],"date-time":"2007-06-11T00:00:00Z","timestamp":1181520000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Pediatr"],"published-print":{"date-parts":[[2007,12]]},"DOI":"10.1186\/1471-2431-7-23","type":"journal-article","created":{"date-parts":[[2007,6,12]],"date-time":"2007-06-12T06:26:36Z","timestamp":1181629596000},"source":"Crossref","is-referenced-by-count":42,"title":["Phono-spectrographic analysis of heart murmur in children"],"prefix":"10.1186","volume":"7","author":[{"given":"Anna-Leena","family":"Noponen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sakari","family":"Lukkarinen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Angerla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raimo","family":"Sepponen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2007,6,11]]},"reference":[{"key":"159_CR1","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/S0002-8703(41)90904-3","volume":"21","author":"MB Rappaport","year":"1941","unstructured":"Rappaport MB, Sprague HB: Physiologic and physical laws that govern auscultation, and their clinical application; the acoustic stethoscope and the electrical amplifying stethoscope and stethograph. Am Heart J. 1941, 21: 257-318. 10.1016\/S0002-8703(41)90904-3.","journal-title":"Am Heart J"},{"key":"159_CR2","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1016\/S0002-8703(07)80050-0","volume":"126","author":"MB Selig","year":"1993","unstructured":"Selig MB: Stethoscope and phonoaudio devices: Historical and future perspectives. Am Heart J. 1993, 126: 262-268.","journal-title":"Am Heart J"},{"key":"159_CR3","doi-asserted-by":"publisher","first-page":"1250","DOI":"10.1161\/01.CIR.93.6.1250","volume":"93","author":"ME Tavel","year":"1996","unstructured":"Tavel ME: Cardiac auscultation. A glorious past\u2013but does it have a future?. Circulation. 1996, 93: 1250-1253.","journal-title":"Circulation"},{"key":"159_CR4","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1161\/01.CIR.11.6.849","volume":"11","author":"VA McKusick","year":"1955","unstructured":"McKusick VA, Webb GN, O'Neal Humphries J, Reid JA: On cardiovascular sound: further observations by means of spectral phonocardiography. Circulation. 1955, 11: 849-870.","journal-title":"Circulation"},{"key":"159_CR5","volume-title":"J & A Churchill London","author":"A Leatham","year":"1970","unstructured":"Leatham A: Auscultation of the Heart and Phonocardiogrphy. J & A Churchill London. 1970"},{"key":"159_CR6","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1001\/archinte.1994.00420080097010","volume":"154","author":"ME Tavel","year":"1994","unstructured":"Tavel ME, Brown DD, Shander D: Enhanced auscultation with a new graphic display system. Arch Intern Med. 1994, 154: 893-898. 10.1001\/archinte.154.8.893.","journal-title":"Arch Intern Med"},{"key":"159_CR7","doi-asserted-by":"publisher","first-page":"1552","DOI":"10.1016\/S0002-9149(97)00194-X","volume":"79","author":"DA Balster","year":"1997","unstructured":"Balster DA, Chan DP, Rowland DG, Hugh DA: Digital acoustic analysis of precordial innocent versus ventricular septal defect murmurs in children. Am J Cardiol. 1997, 79: 1552-1555. 10.1016\/S0002-9149(97)00194-X.","journal-title":"Am J Cardiol"},{"key":"159_CR8","doi-asserted-by":"publisher","first-page":"1638","DOI":"10.1378\/chest.124.5.1638","volume":"124","author":"D Kim","year":"2003","unstructured":"Kim D, Tavel ME: Assessment of severity of aortic stenosis through timefrequency analysis of murmur. Chest. 2003, 124: 1638-1644. 10.1378\/chest.124.5.1638.","journal-title":"Chest"},{"key":"159_CR9","doi-asserted-by":"publisher","first-page":"902","DOI":"10.1016\/j.amjcard.2004.12.018","volume":"95","author":"ME Tavel","year":"2005","unstructured":"Tavel ME, Katz H: Usefulness of a new sound spectral avaraging technique to distinguish an innocent systolic murmur from that of aortic stenosis. Am J Cardiol. 2005, 95: 902-904. 10.1016\/j.amjcard.2004.12.018.","journal-title":"Am J Cardiol"},{"key":"159_CR10","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.1007\/s10439-005-5347-x","volume":"33","author":"A Voss","year":"2005","unstructured":"Voss A, Mix A, Hubner T: Diagnosing aortic valve stenosis by parameter extraction of heart sound signals. Ann Biomed Eng. 2005, 33: 1167-1174. 10.1007\/s10439-005-5347-x.","journal-title":"Ann Biomed Eng"},{"key":"159_CR11","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.1161\/CIRCULATIONAHA.105.591149","volume":"113","author":"ME Tavel","year":"2006","unstructured":"Tavel ME: Cardiac auscultation: a glorious past\u2013and it does have a future!. Circulation. 2006, 113: 1255-1259. 10.1161\/CIRCULATIONAHA.105.591149.","journal-title":"Circulation"},{"key":"159_CR12","first-page":"117","volume":"24","author":"S Lukkarinen","year":"1997","unstructured":"Lukkarinen S, Noponen AL, Siki\u00f6 K, Angerla A: A new phonocardiographic recording system. Comput Cardiol. 1997, 24: 117-120.","journal-title":"Comput Cardiol"},{"key":"159_CR13","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1007\/s002460010253","volume":"22","author":"WR Thompson","year":"2001","unstructured":"Thompson WR, Hayek CS, Tuchinda C, Telford JK, Lombardo JS: Automated cardiac auscultation for detection of pathologic heart murmurs. Pediatr Cardiol. 2001, 22: 373-379.","journal-title":"Pediatr Cardiol"},{"key":"159_CR14","doi-asserted-by":"publisher","first-page":"2711","DOI":"10.1161\/01.CIR.103.22.2711","volume":"103","author":"CG DeGroff","year":"2001","unstructured":"DeGroff CG, Bhatikar S, Hertzberg J, Shandas R, Valdes-Cruz L, Mahajan RL: Artificial neural network-based method of screening heart murmurs in children. Circulation. 2001, 103: 2711-2716.","journal-title":"Circulation"},{"key":"159_CR15","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/j.artmed.2004.07.008","volume":"33","author":"SR Bhatikar","year":"2005","unstructured":"Bhatikar SR, Degroff C, Mahajan RL: A classifier based on the artificial network approach for cardiologic auscultation in pediatrics. Artif Intell Med. 2005, 33: 251-260. 10.1016\/j.artmed.2004.07.008.","journal-title":"Artif Intell Med"},{"issue":"7","key":"159_CR16","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1007\/s10439-005-4053-3","volume":"33","author":"M El-Segaier","year":"2005","unstructured":"El-Segaier M, Lilja O, Lukkarinen S, Sornmo L, Sepponen R, Pesonen E: Computer-based detection and analysis of heart sound and murmur. Ann Biomed Eng. 2005, 33 (7): 937-942. 10.1007\/s10439-005-4053-3.","journal-title":"Ann Biomed Eng"},{"key":"159_CR17","doi-asserted-by":"publisher","first-page":"899","DOI":"10.1115\/1.2049327","volume":"127","author":"N Andresevic","year":"2005","unstructured":"Andresevic N, Ejaz K, Rios-Gutierrez F, Alba-Flores R, Nordehn G, Burns S: Detection of heart murmurs using wavelet analysis and artificial neural networks. J Biomech Eng. 2005, 127: 899-904. 10.1115\/1.2049327.","journal-title":"J Biomech Eng"},{"key":"159_CR18","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1136\/adc.81.5.409","volume":"81","author":"I Haney","year":"1999","unstructured":"Haney I, Ipp M, Feldmen W, McCrindle BW: Accuracy of clinical assessment of heart murmurs by office-based (general practice) paediatricians. Arch Dis Child. 1999, 81: 409-412.","journal-title":"Arch Dis Child"},{"key":"159_CR19","doi-asserted-by":"publisher","first-page":"1184","DOI":"10.1542\/peds.105.6.1184","volume":"105","author":"PRA Gaskin","year":"2000","unstructured":"Gaskin PRA, Owens SE, Talner NS, Sanders SP, Li JS: Clinical auscultation skills in pediatric residents. Pediatrics. 2000, 105: 1184-1187. 10.1542\/peds.105.6.1184.","journal-title":"Pediatrics"},{"key":"159_CR20","doi-asserted-by":"publisher","first-page":"1331","DOI":"10.1542\/peds.113.5.1331","volume":"113","author":"CB Mahnke","year":"2004","unstructured":"Mahnke CB, Nowalk A, Hofkosh D, Zuberbuhler JR, Law YM: Comparison of two educational interventions on pediatric resident auskultation skills. Pediatrics. 2004, 113: 1331-1335. 10.1542\/peds.113.5.1331.","journal-title":"Pediatrics"},{"key":"159_CR21","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1001\/archinte.166.6.610","volume":"166","author":"JM Vukanovic-Criley","year":"2006","unstructured":"Vukanovic-Criley JM, Criley S, Warde CM, Boker JR, Guevara-Matheus L, Churchill WH, Nelson WP, Criley JM: Competency in cardiac examination skills in medical students, trainees, physicians, and faculty: a multicenter study. Arch Intern Med. 2006, 166: 610-616. 10.1001\/archinte.166.6.610.","journal-title":"Arch Intern Med"},{"key":"159_CR22","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1542\/peds.91.2.365","volume":"91","author":"DA Danford","year":"1993","unstructured":"Danford DA, Nasir A, Gumbiner C: Cost assessment of the evaluation of heart murmurs in children. Pediatrics. 1993, 91: 365-368.","journal-title":"Pediatrics"},{"key":"159_CR23","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1177\/000992289503400105","volume":"34","author":"BW McCrindle","year":"1995","unstructured":"McCrindle BW, Shaffer KM, Kan JS, Zahka KG, Rowe SA, Kidd I: An evaluation of parental concerns and misperceptions about heart murmurs. Clin Pediatr. 1995, 34: 25-31.","journal-title":"Clin Pediatr"},{"key":"159_CR24","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1007\/s00246-002-1390-y","volume":"23","author":"DA Danford","year":"2002","unstructured":"Danford DA, Martin AB, Fletcher SE, Cumbiner CH: Echocardiographic yield in children when innocent murmur seems likely but doupts linger. Pediatr Cardiol. 2002, 23: 410-414. 10.1007\/s00246-002-1390-y.","journal-title":"Pediatr Cardiol"},{"key":"159_CR25","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1067\/mpd.2002.124379","volume":"140","author":"RL Geggel","year":"2002","unstructured":"Geggel RL, Horowitz LM, Brown EA, Parsons M, Wang PS, Fulton DR: Parental anxiety associated with referral of a child to a pediatric cardiologist for evaluation of a Still's murmur. J Pediatr. 2002, 140: 747-752. 10.1067\/mpd.2002.124379.","journal-title":"J Pediatr"},{"key":"159_CR26","first-page":"996","volume":"125","author":"G Norgaard","year":"2005","unstructured":"Norgaard G, Greve G, Rosland GA, Berg A: Referral practice and clinical assessment of heart murmurs in children [in Norwegian]. Tidsskr Nor Laegeforen. 2005, 125: 996-998.","journal-title":"Tidsskr Nor Laegeforen"},{"key":"159_CR27","doi-asserted-by":"publisher","first-page":"1443","DOI":"10.4065\/80.11.1443","volume":"80","author":"SK March","year":"2005","unstructured":"March SK, Bedynek JL, Chizner MA: Teatching cardiac Auscultation: effectiveness of a patient-centrered teatching conference on improving cardiac auscultatory skills. Mayo Clin Proc. 2005, 80: 1443-1448.","journal-title":"Mayo Clin Proc"},{"key":"159_CR28","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1378\/chest.126.2.470","volume":"126","author":"MJ Barrett","year":"2004","unstructured":"Barrett MJ, Lacey CS, Sekara AE, Linden EA, Gracely EJ: Mastering cardiac murmurs: the power of repetition. Chest. 2004, 126: 470-475. 10.1378\/chest.126.2.470.","journal-title":"Chest"},{"key":"159_CR29","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1007\/BF00798121","volume":"15","author":"A Van Oort","year":"1994","unstructured":"Van Oort A, Le Blanc-Botden M, De Boo T, Van Der Werf T, Daniels O: The vibratory innocent heart murmur in schoolchildren: difference in auscultatory findings between school medical officers and a pediatric cardiologist. Pediatr Cardiol. 1994, 15: 282-287. 10.1007\/BF00798121.","journal-title":"Pediatr Cardiol"},{"key":"159_CR30","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1001\/archpedi.1996.02170270051007","volume":"150","author":"BW McCrindle","year":"1996","unstructured":"McCrindle BW, Shaffer KM, Kan JS, Zahka KG, Rowe SA, Kidd L: Cardinal clinical signs in the differentiation of heart murmurs in children. Arch Pediatr Adolesc Med. 1996, 150: 169-174.","journal-title":"Arch Pediatr Adolesc Med"},{"key":"159_CR31","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1177\/000992289903800902","volume":"38","author":"K Rajakumar","year":"1999","unstructured":"Rajakumar K, Weisse M, Rosas A, Gunel E, Pyles L, Neal WA, Balian A, Einzig S: Comparative study of clinical evaluation of heart murmurs by general pediatricians and pediatric cardiologists. Clin Pediatr. 1999, 38: 511-518.","journal-title":"Clin Pediatr"},{"key":"159_CR32","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1067\/mhj.2003.173","volume":"145","author":"J Benun","year":"2003","unstructured":"Benun J, Fisher SD, Orav EJ, Schwartz ML, Exil V, Messere C, Lips SE: Cardiac management by pediatricians versus pediatric cardiologists in an inpatient acadmic center. Am Heart J. 2003, 145: 424-429. 10.1067\/mhj.2003.173.","journal-title":"Am Heart J"},{"key":"159_CR33","first-page":"996","volume":"125","author":"G Norgard","year":"2005","unstructured":"Norgard G, Greve G, Rosland GA, Berg A: Referral practice and clinical assesment of heart murmurs in children [in Norwegian]. Tidsskr Nor Laegeforen. 2005, 125: 996-998.","journal-title":"Tidsskr Nor Laegeforen"},{"key":"159_CR34","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1007\/BF00798121","volume":"15","author":"A Van Oort","year":"1994","unstructured":"Van Oort A, Le Blanc-Botden M, De Boo T, Van Der Werf T, Daniels O: The vibratory innocent heart murmur in schoolchildren: difference in auscultatory findings between school medical officers and a pediatric cardiologist. Pediatr Cardiol. 1994, 15: 282-287. 10.1007\/BF00798121.","journal-title":"Pediatr Cardiol"},{"key":"159_CR35","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1001\/archpedi.1996.02170270051007","volume":"150","author":"BW McCrindle","year":"1996","unstructured":"McCrindle BW, Shaffer KM, Kan JS, Zahka KG, Rowe SA, Kidd L: Cardinal clinical signs in the differentiation of heart murmurs in children. Arch Pediatr Adolesc Med. 1996, 150: 169-174.","journal-title":"Arch Pediatr Adolesc Med"},{"key":"159_CR36","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/S0735-1097(97)00101-0","volume":"30","author":"DA Danfor","year":"1997","unstructured":"Danfor DA, Martin AB, Fletcher SE, Gumbiner CH, Cheatham JP, Hofschire PJ, Kugler JD: Children with heart murmurs: can ventricular septal defect be diagnosed reliably without an echocardiogram?. J Am Coll Cardiol. 1997, 30: 243-246. 10.1016\/S0735-1097(97)00101-0.","journal-title":"J Am Coll Cardiol"},{"key":"159_CR37","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/S0022-3476(99)70375-6","volume":"134","author":"DA Danford","year":"1999","unstructured":"Danford DA, Salaymeh KJ, Martin AB, Fletcher SE, Gumbiner CH: Pulmonary stenosis: defect-spesific diagnostic accurancy of heart murmurs in children. J Pediatr. 1999, 134: 76-81. 10.1016\/S0022-3476(99)70375-6.","journal-title":"J Pediatr"},{"key":"159_CR38","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1253\/circj.67.112","volume":"67","author":"H Muta","year":"2003","unstructured":"Muta H, Akagi T, Egami K, Furui J, Sugahara Y, Ishii M, Matsuishi T: Incidence and clinical features of asymptomatic atrial septal defect in scool children diagnosed by heart disease screening. Circ J. 2003, 67: 112-115. 10.1253\/circj.67.112.","journal-title":"Circ J"},{"key":"159_CR39","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1007\/BF00798120","volume":"15","author":"A Van Oort","year":"1994","unstructured":"Van Oort A, Hopman J, De Boo T, Van Der Werf T, Rohmer J, Daniels O: The vibratory innocent heart murmur in schoolchildren: A case-control doppler echocardiographic study. Pediatric Cardiol. 1994, 15: 275-281. 10.1007\/BF00798120.","journal-title":"Pediatric Cardiol"},{"key":"159_CR40","doi-asserted-by":"publisher","first-page":"82","DOI":"10.3928\/0090-4481-19970201-05","volume":"26","author":"IH Gessner","year":"1997","unstructured":"Gessner IH: What makes a heart murmur innocent. Pediatric Annals. 1997, 26: 82-91.","journal-title":"Pediatric Annals"},{"key":"159_CR41","doi-asserted-by":"publisher","first-page":"1515","DOI":"10.1016\/j.pcl.2004.08.004","volume":"51","author":"AN Pelech","year":"2004","unstructured":"Pelech AN: The physiolgy of cardiac auscultation. Pediatr Clin North Am. 2004, 51: 1515-1535. 10.1016\/j.pcl.2004.08.004.","journal-title":"Pediatr Clin North Am"},{"key":"159_CR42","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1161\/01.CIR.0000153388.41229.CB","volume":"111","author":"T Biancaniello","year":"2005","unstructured":"Biancaniello T: Innocent murmurs. Circulation. 2005, 111: 20-22. 10.1161\/01.CIR.0000153388.41229.CB.","journal-title":"Circulation"},{"key":"159_CR43","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1017\/S104795110000963X","volume":"10","author":"N Advani","year":"2000","unstructured":"Advani N, Menahem S, Wilkinson JL: The diagnosis of innocent murmur in childhood. Cardiol Young. 2000, 10: 340-342.","journal-title":"Cardiol Young"},{"key":"159_CR44","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1016\/0002-9149(94)90917-2","volume":"74","author":"RL Donnerstein","year":"1994","unstructured":"Donnerstein RL, Thomssen VS: Hemodynamic and anatomic factors affecting the frequency content of Still's innocent murmur. Am J Cardiol. 1994, 74: 508-510. 10.1016\/0002-9149(94)90917-2.","journal-title":"Am J Cardiol"},{"key":"159_CR45","first-page":"561","volume":"27","author":"AL Noponen","year":"2000","unstructured":"Noponen AL, Lukkarinen S, Siki\u00f6 K, Angerla A, Sepponen R: How to recognize the innocent vibratory murmur. Comput Cardiol. 2000, 27: 561-564.","journal-title":"Comput Cardiol"},{"key":"159_CR46","volume-title":"Heart auscultation: audio samples and phonocardiograms. In: Evidence-Based Medicine Guidelines [online]","author":"S Lukkarinen","year":"2004","unstructured":"Lukkarinen S, Noponen AL: Heart auscultation: audio samples and phonocardiograms. In: Evidence-Based Medicine Guidelines [online]. 2004, Helsinki, Duodecim Medical Publications Ltd, WWW-document (password required):, [ http:\/\/www.ebm-guidelines.com\/ ]"},{"key":"159_CR47","first-page":"53","volume":"25","author":"S Lukkarinen","year":"1998","unstructured":"Lukkarinen S, Noponen AL, Angerla A, Siki\u00f6 K, Sepponen R: Experiences in videoconference system in heart murmur screening. Comput Cardiol. 1998, 25: 53-56.","journal-title":"Comput Cardiol"},{"key":"159_CR48","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1136\/adc.87.4.297","volume":"87","author":"LB Dahl","year":"2002","unstructured":"Dahl LB, Hasvold P, Arild E, Hasvold T: Heart murmurs recorded by a sensor based electronic stethoscope and e-mailed for remote assessment. Arch Dis Child. 2002, 87: 297-300. 10.1136\/adc.87.4.297.","journal-title":"Arch Dis Child"},{"key":"159_CR49","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1542\/peds.112.4.780","volume":"112","author":"JM Belmont","year":"2003","unstructured":"Belmont JM, Mattioli LF: Accurancy of analog telephonic stethoscopy for pediatric telecardiology. Pediatrics. 2003, 112: 780-786. 10.1542\/peds.112.4.780.","journal-title":"Pediatrics"}],"container-title":["BMC Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2431-7-23\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2431-7-23.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2431-7-23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2431-7-23.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,12]],"date-time":"2023-05-12T10:50:54Z","timestamp":1683888654000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcpediatr.biomedcentral.com\/articles\/10.1186\/1471-2431-7-23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,6,11]]},"references-count":49,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,12]]}},"alternative-id":["159"],"URL":"https:\/\/doi.org\/10.1186\/1471-2431-7-23","relation":{},"ISSN":["1471-2431"],"issn-type":[{"value":"1471-2431","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,6,11]]},"article-number":"23"}}