{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T02:50:13Z","timestamp":1771469413221,"version":"3.50.1"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2008,6,2]],"date-time":"2008-06-02T00:00:00Z","timestamp":1212364800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Pediatr"],"published-print":{"date-parts":[[2008,12]]},"DOI":"10.1186\/1471-2431-8-23","type":"journal-article","created":{"date-parts":[[2008,6,3]],"date-time":"2008-06-03T06:13:33Z","timestamp":1212473613000},"source":"Crossref","is-referenced-by-count":58,"title":["Compared to placebo, long-term antibiotics resolve otitis media with effusion (OME) and prevent acute otitis media with perforation (AOMwiP) in a high-risk population: A randomized controlled trial"],"prefix":"10.1186","volume":"8","author":[{"name":"the Chronic Otitis Media Intervention Trial \u2013 One (COMIT1) group","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda J","family":"Leach","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter S","family":"Morris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John D","family":"Mathews","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,6,2]]},"reference":[{"key":"200_CR1","volume-title":"World Health Organization (WHO)","author":"J Acuin","year":"2006","unstructured":"Acuin J: Chronic suppurative otitis media: Burden of illness and management options. World Health Organization (WHO). 2006"},{"key":"200_CR2","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/1471-2431-5-27","volume":"5","author":"PS Morris","year":"2005","unstructured":"Morris PS, Leach AJ, Silberberg P, Mellon G, Wilson C, Hamilton E, Beissbarth J: Otitis media in young Aboriginal children from remote communities in Northern and Central Australia: a cross-sectional survey. BMC Pediatr. 2005, 5: 27-37. 10.1186\/1471-2431-5-27.","journal-title":"BMC Pediatr"},{"key":"200_CR3","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1097\/00006454-199411000-00009","volume":"13","author":"AJ Leach","year":"1994","unstructured":"Leach AJ, Boswell JB, Asche V, Nienhuys TG, Mathews JD: Bacterial colonization of the nasopharynx predicts very early onset and persistence of otitis media in Australian aboriginal infants. Pediatr Infect Dis J. 1994, 13: 983-989.","journal-title":"Pediatr Infect Dis J"},{"key":"200_CR4","volume-title":"Evidence-Based Otitis Media","author":"RM Rosenfeld","year":"2003","unstructured":"Rosenfeld RM, Bluestone CD: Evidence-Based Otitis Media. 2003, Second Edition. BC Decker Inc.","edition":"Second Edition."},{"key":"200_CR5","doi-asserted-by":"publisher","first-page":"1344","DOI":"10.1001\/jama.1993.03510110084037","volume":"270","author":"RL Williams","year":"1993","unstructured":"Williams RL, Chalmers TC, Stange KC, Chalmers FT, Bowlin SJ: Use of antibiotics in preventing recurrent acute otitis media and in treating otitis media with effusion. A meta-analytic attempt to resolve the brouhaha. JAMA. 1993, 270: 1344-1351. 10.1001\/jama.270.11.1344.","journal-title":"JAMA"},{"key":"200_CR6","doi-asserted-by":"publisher","first-page":"1429","DOI":"10.1016\/S0140-6736(06)69606-2","volume":"368","author":"MM Rovers","year":"2006","unstructured":"Rovers MM, Glasziou P, Appelman CL, Burke P, McCormick DP, Damoiseaux RA, Gaboury I, Little P, Hoes AW: Antibiotics for acute otitis media: a meta-analysis with individual patient data. Lancet. 2006, 368: 1429-1435. 10.1016\/S0140-6736(06)69606-2.","journal-title":"Lancet"},{"key":"200_CR7","volume-title":"Central Australian Rural Practitioners Association (CARPA) Standard Treatment Manual","author":"Central Australian Rural Practitioners Association (CARPA)","year":"2003","unstructured":"Central Australian Rural Practitioners Association (CARPA): Central Australian Rural Practitioners Association (CARPA) Standard Treatment Manual. 2003, Alice Springs, Australia, Central Australian Rural Practitioners Association (CARPA), 4th edition.","edition":"4th edition."},{"key":"200_CR8","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1097\/01.inf.0000160945.87356.ca","volume":"24","author":"E Stubbs","year":"2005","unstructured":"Stubbs E, Hare K, Wilson C, Morris P, Leach AJ: Streptococcus pneumoniae and noncapsular Haemophilus influenzae nasal carriage and hand contamination in children: a comparison of two populations at risk of otitis media. Pediatr Infect Dis J. 2005, 24: 423-428. 10.1097\/01.inf.0000160945.87356.ca.","journal-title":"Pediatr Infect Dis J"},{"key":"200_CR9","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1111\/j.1472-765X.1986.tb01565.x","volume":"3","author":"LF Gibson","year":"1986","unstructured":"Gibson LF, Khoury JT: Storage and survival of bacteria by ultra-freeze. Letter Appl Microbiol. 1986, 3: 127-129. 10.1111\/j.1472-765X.1986.tb01565.x.","journal-title":"Letter Appl Microbiol"},{"key":"200_CR10","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1097\/00006454-200302000-00009","volume":"22","author":"KL O'Brien","year":"2003","unstructured":"O'Brien KL, Nohynek H: Report from a WHO working group: standard method for detecting upper respiratory carriage of Streptococcus pneumoniae. Pediatr Infect Dis J. 2003, 22: 133-140. 10.1097\/00006454-200302000-00009.","journal-title":"Pediatr Infect Dis J"},{"key":"200_CR11","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1186\/1471-2431-5-16","volume":"5","author":"KB Gibney","year":"2005","unstructured":"Gibney KB, Morris PS, Carapetis JR, Skull SA, Smith-Vaughan HC, Stubbs E, Leach AJ: The clinical course of acute otitis media in high-risk Australian Aboriginal children: a longitudinal study. BMC Pediatr. 2005, 5: 16-24. 10.1186\/1471-2431-5-16.","journal-title":"BMC Pediatr"},{"key":"200_CR12","volume-title":"Stata Corporation","author":"StataCorp","year":"2004","unstructured":"StataCorp: Stata Statistical Software: Release 8.2. College Station, Texas:. Stata Corporation. 2004"},{"key":"200_CR13","first-page":"Oral Presentati","volume":"SY12.06","author":"JR Gadil","year":"2006","unstructured":"Gadil JR, Leach AJ, Morris PS, Hopkin S, Beissbarth J, Hare K, Kennedy M, Smith-Vaughan H, Torzillo P: Azithromycin versus Amoxycillin for Acute Otitis Media in Aboriginal Children (AATAAC): a double blind randomised controlled trial. International Symposium on Pneumococci and Pneumococcal Diseases. 2006, SY12.06: Oral Presentation-","journal-title":"International Symposium on Pneumococci and Pneumococcal Diseases"},{"key":"200_CR14","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1542\/peds.113.5.1451","volume":"113","author":"Subcommittee on Management of Acute Otitis Media","year":"2004","unstructured":"Subcommittee on Management of Acute Otitis Media: Diagnosis and Management of Acute Otitis Media. Pediatrics. 2004, 113: 1451-1465. 10.1542\/peds.113.5.1451.","journal-title":"Pediatrics"},{"key":"200_CR15","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/1472-6815-6-10","volume":"6","author":"HC Smith-Vaughan","year":"2006","unstructured":"Smith-Vaughan HC, Byun R, Nadkarni M, Jacques NA, Hunter N, Halpin S, Morris PS, Leach AJ: Measuring nasal bacterial load and its association with otitis media. BMC Ear Nose Throat Disord. 2006, 6: 10-19. 10.1186\/1472-6815-6-10.","journal-title":"BMC Ear Nose Throat Disord"},{"key":"200_CR16","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1542\/peds.2004-2056","volume":"115","author":"H Hoover","year":"2005","unstructured":"Hoover H, Roddey OF: The Overlooked Importance of Tympanic Membrane Bulging. Pediatrics. 2005, 115: 513-10.1542\/peds.2004-2056.","journal-title":"Pediatrics"},{"key":"200_CR17","volume-title":"Recommendations for clinical care guidelines on the management of otitis media in Aboriginal and Torres Strait Islander populations","author":"PS Morris","year":"2001","unstructured":"Morris PS, Ballinger D, Leach AJ, Koops H, Hayhurst B, Stubbs E, Scott J, Anand A, Daby J, Paterson B, Yonovitz A: Recommendations for clinical care guidelines on the management of otitis media in Aboriginal and Torres Strait Islander populations. 2001, Canberra, Office of Aboriginal and Torres Strait Islander Health"},{"key":"200_CR18","first-page":"CD004401","volume-title":"Cochrane Database Syst Rev","author":"AJ Leach","year":"2006","unstructured":"Leach AJ, Morris PS: Antibiotics for the prevention of acute and chronic suppurative otitis media in children. Cochrane Database Syst Rev. 2006, CD004401-"},{"key":"200_CR19","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1001\/jama.1972.03190310029006","volume":"219","author":"JE Maynard","year":"1972","unstructured":"Maynard JE, Fleshman JK, Tschopp CF: Otitis media in Alaskan Eskimo children. Prospective evaluation of chemoprophylaxis. JAMA. 1972, 219: 597-599. 10.1001\/jama.219.5.597.","journal-title":"JAMA"},{"key":"200_CR20","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1017\/S0022172400060782","volume":"95","author":"D Hansman","year":"1985","unstructured":"Hansman D, Morris S, Gregory MM, McDonald B: Pneumococcal carriage amongst Australian aborigines in Alice Springs, Northern Territory. J Hyg Camb. 1985, 95: 677-84.","journal-title":"J Hyg Camb"},{"key":"200_CR21","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1097\/01.inf.0000178072.83531.4f","volume":"24","author":"RKM Syrjanen","year":"2005","unstructured":"Syrjanen RKM, Auranen KJP, Leino TMM, Kilpi TMM, Makela PHMD: Pneumococcal Acute Otitis Media in Relation to Pneumococcal Nasopharyngeal Carriage. [Article]. Pediatric Infectious Disease Journal. 2005, 24: 801-806. 10.1097\/01.inf.0000178072.83531.4f.","journal-title":"Pediatric Infectious Disease Journal"},{"key":"200_CR22","doi-asserted-by":"crossref","first-page":"519","DOI":"10.5694\/j.1326-5377.2007.tb01026.x","volume":"186","author":"J Rothstein","year":"2007","unstructured":"Rothstein J, Heazlewood R, Fraser M: Health of Aboriginal and Torres Strait Islander children in remote Far North Queensland: findings of the Paediatric Outreach Service. Med J Aust. 2007, 186: 519-521.","journal-title":"Med J Aust"},{"key":"200_CR23","volume-title":"Learning lessons. An independent review of Indigenous education in the Northern Territory","author":"B Collins","year":"1999","unstructured":"Collins B: Learning lessons. An independent review of Indigenous education in the Northern Territory. 1999"}],"container-title":["BMC Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2431-8-23\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2431-8-23.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2431-8-23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2431-8-23.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,6]],"date-time":"2020-05-06T03:19:33Z","timestamp":1588735173000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcpediatr.biomedcentral.com\/articles\/10.1186\/1471-2431-8-23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,6,2]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["200"],"URL":"https:\/\/doi.org\/10.1186\/1471-2431-8-23","relation":{},"ISSN":["1471-2431"],"issn-type":[{"value":"1471-2431","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,6,2]]},"article-number":"23"}}