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We hypothesized that patients with obesity and no objective documentation of airflow obstruction are inappropriately treated with bronchodilators.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>Spirometric results and medical records of all patients with body mass index &gt;30\u00a0kg\/m<jats:sup>2<\/jats:sup> who were referred for testing between March 2010 and August 2011 were analyzed.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>155 patients with mean age of 52.6\u2009\u00b1\u2009(SE)1.1 y and BMI of 38.7\u2009\u00b1\u20090.7\u00a0kg\/m<jats:sup>2<\/jats:sup> were studied. Spirometry showed normal respiratory mechanics in 62 (40%), irreversible airflow obstruction in 36 (23.2%), flows suggestive of restriction in 35 (22.6%), reversible obstruction, suggestive of asthma in 11 (7.1%), and mixed pattern (obstructive and restrictive) in 6 (3.9%). Prior to testing, 45.2% (28 of 62) of patients with normal spirometry were being treated with medications for obstructive lung diseases and 33.9% (21 of 62) continued them despite absence of airflow obstruction on spirometry. 60% (21 of 35) of patients with a restrictive pattern in their spirometry received treatment for obstruction prior to spirometry and 51.4% (18 of 35) continued bronchodilator therapy after spirometric testing. There was no independent association of non-indicated treatment with spirometric results, age, BMI, co-morbidities or smoking history. All patients with airflow obstruction on testing who were receiving bronchodilators before spirometry continued to receive them after testing.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>A substantial proportion of patients with obesity referred for pulmonary function testing did not have obstructive lung disease, but were treated nonetheless, before and after spirometry demonstrating absence of airway obstruction.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1471-2466-13-68","type":"journal-article","created":{"date-parts":[[2013,11,22]],"date-time":"2013-11-22T16:02:40Z","timestamp":1385136160000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Perseverant, non-indicated treatment of obese patients for obstructive lung disease"],"prefix":"10.1186","volume":"13","author":[{"given":"Spyridon","family":"Fortis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Kittah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"De Aguirre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Plataki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armand","family":"Wolff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaw","family":"Amoateng-Adjepong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Constantine A","family":"Manthous","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,11,22]]},"reference":[{"issue":"2","key":"445_CR1","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1093\/fampra\/cmn006","volume":"25","author":"AE Lucas","year":"2008","unstructured":"Lucas AE, Smeenk FW, Smeele IJ, van Schayck CP: Overtreatment with inhaled corticosteroids and diagnostic problems in primary care patients, an exploratory study. 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