{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T02:21:47Z","timestamp":1793931707912,"version":"4.8.0"},"reference-count":60,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2014,1,10]],"date-time":"2014-01-10T00:00:00Z","timestamp":1389312000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Pulm Med"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1186\/1471-2466-14-3","type":"journal-article","created":{"date-parts":[[2014,1,10]],"date-time":"2014-01-10T13:57:16Z","timestamp":1389362236000},"source":"Crossref","is-referenced-by-count":45,"title":["Pharmacologic inhibition of S-nitrosoglutathione reductase protects against experimental asthma in BALB\/c mice through attenuation of both bronchoconstriction and inflammation"],"prefix":"10.1186","volume":"14","author":[{"given":"Joan P","family":"Blonder","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah C","family":"Mutka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xicheng","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia H","family":"Green","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Navdeep K","family":"Mehra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramakrishna","family":"Boyanapalli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Suniga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsten","family":"Look","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Delany","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane P","family":"Richards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doug","family":"Looker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Scoggin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary J","family":"Rosenthal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,1,10]]},"reference":[{"key":"454_CR1","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1038\/nrm1569","volume":"6","author":"DT Hess","year":"2005","unstructured":"Hess DT, Matsumoto A, Kim SO, Marshall HE, Stamler JS: Protein S-nitrosylation: purview and parameters. Nat Rev Mol Cell Biol. 2005, 6: 150-166. 10.1038\/nrm1569.","journal-title":"Nat Rev Mol Cell Biol"},{"key":"454_CR2","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1146\/annurev.pharmtox.42.092501.104328","volume":"42","author":"N Hogg","year":"2002","unstructured":"Hogg N: The biochemistry and physiology of S-nitrosothiols. Annu Rev Pharmacol Toxicol. 2002, 42: 585-600. 10.1146\/annurev.pharmtox.42.092501.104328.","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"454_CR3","doi-asserted-by":"publisher","first-page":"10957","DOI":"10.1073\/pnas.90.23.10957","volume":"90","author":"B Gaston","year":"1993","unstructured":"Gaston B, Reilly J, Drazen JM, Fackler J, Ramdev P, Arnelle D, Mullins ME, Sugarbaker DJ, Chee C, Singel DJ: Endogenous nitrogen oxides and bronchodilator S-nitrosothiols in human airways. Proc Natl Acad Sci USA. 1993, 90: 10957-10961. 10.1073\/pnas.90.23.10957.","journal-title":"Proc Natl Acad Sci USA"},{"key":"454_CR4","doi-asserted-by":"publisher","first-page":"1561","DOI":"10.1161\/01.RES.66.6.1561","volume":"66","author":"M Kelm","year":"1990","unstructured":"Kelm M, Schrader J: Control of coronary vascular tone by nitric oxide. Circ Res. 1990, 66: 1561-1575. 10.1161\/01.RES.66.6.1561.","journal-title":"Circ Res"},{"key":"454_CR5","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1016\/j.molmed.2009.06.007","volume":"15","author":"MW Foster","year":"2009","unstructured":"Foster MW, Hess DT, Stamler JS: Protein S-nitrosylation in health and disease: a current perspective. Trends Mol Med. 2009, 15: 391-404. 10.1016\/j.molmed.2009.06.007.","journal-title":"Trends Mol Med"},{"key":"454_CR6","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1152\/physrev.00029.2006","volume":"87","author":"P Pacher","year":"2007","unstructured":"Pacher P, Beckman JS, Liaudet L: Nitric oxide and peroxynitrite in health and disease. Physiol Rev. 2007, 87: 315-424. 10.1152\/physrev.00029.2006.","journal-title":"Physiol Rev"},{"key":"454_CR7","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1007\/s000110050729","volume":"50","author":"JD Fortenberry","year":"2001","unstructured":"Fortenberry JD, Owens ML, Chen NX, Brown LA: S-nitrosoglutathione inhibits TNF-alpha-induced NFkappaB activation in neutrophils. Inflamm Res. 2001, 50: 89-95. 10.1007\/s000110050729.","journal-title":"Inflamm Res"},{"key":"454_CR8","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1152\/physrev.00034.2003","volume":"84","author":"FL Ricciardolo","year":"2004","unstructured":"Ricciardolo FL, Sterk PJ, Gaston B, Folkerts G: Nitric oxide in health and disease of the respiratory system. Physiol Rev. 2004, 84: 731-765. 10.1152\/physrev.00034.2003.","journal-title":"Physiol Rev"},{"key":"454_CR9","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1016\/j.cell.2007.02.046","volume":"129","author":"EJ Whalen","year":"2007","unstructured":"Whalen EJ, Foster MW, Matsumoto A, Ozawa K, Violin JD, Que LG, Nelson CD, Benhar M, Keys JR, Rockman HA, Koch WJ, Daaka Y, Lefkowitz RJ, Stamler JS: Regulation of \u03b2-adrenergic receptor signaling by s-nitrosylation of g protein-coupled receptor kinase 2. Cell. 2007, 129: 511-522. 10.1016\/j.cell.2007.02.046.","journal-title":"Cell"},{"key":"454_CR10","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1042\/bj3310659","volume":"331","author":"DE Jensen","year":"1998","unstructured":"Jensen DE, Belka GK, Du Bois GC: S-nitrosoglutathione is a substrate for rat alcohol dehydrogenase class III isoenzyme. Biochem J. 1998, 331: 659-668.","journal-title":"Biochem J"},{"key":"454_CR11","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1038\/35068596","volume":"410","author":"L Liu","year":"2001","unstructured":"Liu L, Hausladen A, Zeng M, Que L, Heitman J, Stamler JS: A metabolic enzyme for S-nitrosothiol conserved from bacteria to humans. Nature. 2001, 410: 490-494. 10.1038\/35068596.","journal-title":"Nature"},{"key":"454_CR12","doi-asserted-by":"publisher","first-page":"1186","DOI":"10.1164\/rccm.200510-1584PP","volume":"173","author":"B Gaston","year":"2006","unstructured":"Gaston B, Singel D, Doctor A, Stamler JS: S-nitrosothiol signaling in respiratory biology. Am J Respir Crit Care Med. 2006, 173: 1186-1193. 10.1164\/rccm.200510-1584PP.","journal-title":"Am J Respir Crit Care Med"},{"key":"454_CR13","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1164\/rccm.200901-0158OC","volume":"180","author":"LG Que","year":"2009","unstructured":"Que LG, Yang Z, Stamler JS, Lugogo NL, Kraft M: S-nitrosoglutathione reductase \u2013 an important regulator in human asthma. Am J Respir Crit Care Med. 2009, 180: 226-231. 10.1164\/rccm.200901-0158OC.","journal-title":"Am J Respir Crit Care Med"},{"key":"454_CR14","doi-asserted-by":"publisher","first-page":"1317","DOI":"10.1016\/S0140-6736(97)07485-0","volume":"351","author":"B Gaston","year":"1998","unstructured":"Gaston B, Sears S, Woods J, Hunt J, Ponaman M, McMahon T, Stamler JS: Bronchodilator S-nitrosothiol deficiency in asthmatic respiratory failure. Lancet. 1998, 351: 1317-1319. 10.1016\/S0140-6736(97)07485-0.","journal-title":"Lancet"},{"key":"454_CR15","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1097\/FPC.0b013e328337f992","volume":"6","author":"S Choudhry","year":"2010","unstructured":"Choudhry S, Que LG, Yang Z, Liu L, Eng C, Kim SO, Kumar G, Thyne S, Chapela R, Rodriguez-Santana JR, Rodriguez-Cintron W, Avila PC, Stamler JS, Burchard EG: GSNO reductase and beta2-adrenergic receptor gene-gene interaction: bronchodilator responsiveness to albuterol. Pharmacogenet Genomics. 2010, 6: 351-358.","journal-title":"Pharmacogenet Genomics"},{"key":"454_CR16","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1002\/ppul.21033","volume":"44","author":"PE Moore","year":"2009","unstructured":"Moore PE, Ryckman KK, Williams SM, Patel N, Summar ML, Sheller JR: Genetic variants of GSNOR and ADRB2 influence response to albuterol in African-American children with severe asthma. Pediatr Pulmonol. 2009, 44: 649-654. 10.1002\/ppul.21033.","journal-title":"Pediatr Pulmonol"},{"key":"454_CR17","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1016\/j.jaci.2007.04.022","volume":"120","author":"H Wu","year":"2007","unstructured":"Wu H, Romieu I, Sienra-Monge JJ, Estela DR-N, Anderson DM, Jenchura CA, Li H, Ramirez-Aguilar M, Del CL-SI, London SJ: Genetic variation in S-nitrosoglutathione reductase (GSNOR) and childhood asthma. J Allergy Clin Immunol. 2007, 120: 322-328. 10.1016\/j.jaci.2007.04.022.","journal-title":"J Allergy Clin Immunol"},{"key":"454_CR18","doi-asserted-by":"publisher","first-page":"1618","DOI":"10.1126\/science.1108228","volume":"308","author":"LG Que","year":"2005","unstructured":"Que LG, Liu L, Yan Y, Whitehead GS, Gavett SH, Schwartz DA, Stamler JS: Protection from experimental asthma by an endogenous bronchodilator. Science. 2005, 308: 1618-1621. 10.1126\/science.1108228.","journal-title":"Science"},{"key":"454_CR19","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1164\/rccm.200403-408OC","volume":"170","author":"AF Gelb","year":"2004","unstructured":"Gelb AF, Taylor CF, Nussbaum E, Gutierrez C, Schein A, Shinar CM, Schein MJ, Epstein JD, Zamel N: Alveolar and airway sites of nitric oxide inflammation in treated asthma. Am J Respir Crit Care Med. 2004, 170: 737-741. 10.1164\/rccm.200403-408OC.","journal-title":"Am J Respir Crit Care Med"},{"key":"454_CR20","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/j.ejphar.2005.12.069","volume":"533","author":"AE Redington","year":"2006","unstructured":"Redington AE: Modulation of nitric oxide pathways: therapeutic potential in asthma and chronic obstructive pulmonary disease. Eur J Pharmacol. 2006, 533: 263-276. 10.1016\/j.ejphar.2005.12.069.","journal-title":"Eur J Pharmacol"},{"key":"454_CR21","doi-asserted-by":"publisher","first-page":"2163","DOI":"10.1056\/NEJMoa043596","volume":"352","author":"AD Smith","year":"2005","unstructured":"Smith AD, Cowan JO, Brassett KP, Herbison GP, Taylor DR: Use of exhaled nitric oxide measurements to guide treatment in chronic asthma. N Engl J Med. 2005, 352: 2163-2173. 10.1056\/NEJMoa043596.","journal-title":"N Engl J Med"},{"key":"454_CR22","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/S0065-7743(09)04402-9","volume-title":"Annual Reports in Medicinal Chemistry. Volume 44","author":"S Maddaford","year":"2009","unstructured":"Maddaford S, Annedi SC, Ramnauth J, Rakhit S: Advances in the development of nitric oxide synthase inhibitors. Annual Reports in Medicinal Chemistry. Volume 44. Edited by: Macor JE. 2009, Salt Lake City: Elsevier, Inc, 27-50."},{"key":"454_CR23","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1038\/nrd960","volume":"1","author":"P Vallance","year":"2002","unstructured":"Vallance P, Leiper J: Blocking NO synthesis: how, where and why?. Nat Rev Drug Discov. 2002, 1: 939-950. 10.1038\/nrd960.","journal-title":"Nat Rev Drug Discov"},{"key":"454_CR24","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1042\/cs0980507","volume":"98","author":"H Al-Sa\u2019doni","year":"2000","unstructured":"Al-Sa\u2019doni H, Ferro A: S-Nitrosothiols: a class of nitric oxide-donor drugs. Clin Sci (Lond). 2000, 98: 507-520. 10.1042\/CS19990267.","journal-title":"Clin Sci (Lond)"},{"key":"454_CR25","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/S0163-7258(02)00262-0","volume":"95","author":"BJ Nevin","year":"2002","unstructured":"Nevin BJ, Broadley KJ: Nitric oxide in respiratory diseases. Pharmacol Ther. 2002, 95: 259-293. 10.1016\/S0163-7258(02)00262-0.","journal-title":"Pharmacol Ther"},{"key":"454_CR26","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1080\/10715769900301161","volume":"31","author":"DS Bredt","year":"1999","unstructured":"Bredt DS: Endogenous nitric oxide synthesis: biological functions and pathophysiology. Free Radic Res. 1999, 31: 577-596. 10.1080\/10715769900301161.","journal-title":"Free Radic Res"},{"key":"454_CR27","doi-asserted-by":"publisher","first-page":"6297","DOI":"10.1073\/pnas.0901043106","volume":"106","author":"B Lima","year":"2009","unstructured":"Lima B, Lam GK, Xie L, Diesen DL, Villamizar N, Nienaber J, Messina E, Bowles D, Kontos CD, Hare JM, Stamler JS, Rockman HA: Endogenous S-nitrosothiols protect against myocardial injury. Proc Natl Acad Sci USA. 2009, 106: 6297-6302. 10.1073\/pnas.0901043106.","journal-title":"Proc Natl Acad Sci USA"},{"key":"454_CR28","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.mam.2004.09.003","volume":"26","author":"KM Naseem","year":"2005","unstructured":"Naseem KM: The role of nitric oxide in cardiovascular diseases. Mol Aspects Med. 2005, 26: 33-65. 10.1016\/j.mam.2004.09.003.","journal-title":"Mol Aspects Med"},{"key":"454_CR29","doi-asserted-by":"publisher","first-page":"1344","DOI":"10.1053\/j.gastro.2007.01.051","volume":"132","author":"TC Savidge","year":"2007","unstructured":"Savidge TC, Newman P, Pothoulakis C, Ruhl A, Neunlist M, Bourreille A, Hurst R, Sofroniew MV: Enteric glia regulate intestinal barrier function and inflammation via release of S-nitrosoglutathione. Gastroenterology. 2007, 132: 1344-1358. 10.1053\/j.gastro.2007.01.051.","journal-title":"Gastroenterology"},{"key":"454_CR30","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1038\/labinvest.3700600","volume":"87","author":"TC Savidge","year":"2007","unstructured":"Savidge TC, Sofroniew MV, Neunlist M: Starring roles for astroglia in barrier pathologies of gut and brain. Lab Invest. 2007, 87: 731-736. 10.1038\/labinvest.3700600.","journal-title":"Lab Invest"},{"key":"454_CR31","doi-asserted-by":"publisher","first-page":"2157","DOI":"10.1021\/bi201785u","volume":"51","author":"LS Green","year":"2012","unstructured":"Green LS, Chun LE, Patton AK, Sun X, Rosenthal GJ, Richards JP: Mechanism of inhibition for N6022, a first-in-class drug targeting S-nitrosoglutathione reductase. Biochemistry. 2012, 51: 2157-2168. 10.1021\/bi201785u.","journal-title":"Biochemistry"},{"key":"454_CR32","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1021\/ml200045s","volume":"2","author":"X Sun","year":"2011","unstructured":"Sun X, Wasley J, Qiu J, Blonder J, Stout A, Green L, Strong S, Colagiovanni D, Richards J, Mutka S, Chun L, Rosenthal G: Discovery of S-nitrosoglutathione reductase inhibitors: potential agents for the treatment of asthma and other inflammatory diseases. ACS Med Chem Lett. 2011, 2: 402-406. 10.1021\/ml200045s.","journal-title":"ACS Med Chem Lett"},{"key":"454_CR33","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1164\/ajrccm.156.3.9606031","volume":"156","author":"E Hamelmann","year":"1997","unstructured":"Hamelmann E, Schwarze J, Takeda K, Oshiba A, Larsen GL, Irvin CG, Gelfand EW: Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography. Am J Respir Crit Care Med. 1997, 156: 766-775. 10.1164\/ajrccm.156.3.9606031.","journal-title":"Am J Respir Crit Care Med"},{"key":"454_CR34","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.yrtph.2011.12.012","volume":"62","author":"DB Colagiovanni","year":"2012","unstructured":"Colagiovanni DB, Drolet DW, Langlois-Forget E, Piche MP, Looker D, Rosenthal GJ: A nonclinical safety and pharmacokinetic evaluation of N6022: a first-in-class S-nitrosoglutathione reductase inhibitor for the treatment of asthma. Regul Toxicol Pharmacol. 2012, 62: 115-124. 10.1016\/j.yrtph.2011.12.012.","journal-title":"Regul Toxicol Pharmacol"},{"key":"454_CR35","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/S0076-6879(07)00808-7","volume":"440","author":"S Basu","year":"2008","unstructured":"Basu S, Wang X, Gladwin MT, Kim-Shapiro DB: Chemiluminescent detection of S-nitrosated proteins: comparison of tri-iodide, copper\/CO\/cysteine, and modified copper\/cysteine methods. Methods Enzymol. 2008, 440: 137-156.","journal-title":"Methods Enzymol"},{"key":"454_CR36","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1038\/sj.embor.7400627","volume":"7","author":"R Feil","year":"2006","unstructured":"Feil R, Kemp-Harper B: cGMP signalling: from bench to bedside. Conference on cGMP generators, effectors and therapeutic implications. EMBO Rep. 2006, 7: 149-153. 10.1038\/sj.embor.7400627.","journal-title":"EMBO Rep"},{"key":"454_CR37","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1513\/pats.200806-054RM","volume":"6","author":"YM Janssen-Heininger","year":"2009","unstructured":"Janssen-Heininger YM, Poynter ME, Aesif SW, Pantano C, Ather JL, Reynaert NL, Ckless K, Anathy V, Van DV, Irvin CG, Van DV: Nuclear factor kappaB, airway epithelium, and asthma: avenues for redox control. Proc Am Thorac Soc. 2009, 6: 249-255. 10.1513\/pats.200806-054RM.","journal-title":"Proc Am Thorac Soc"},{"key":"454_CR38","doi-asserted-by":"publisher","first-page":"8841","DOI":"10.1073\/pnas.0403034101","volume":"101","author":"HE Marshall","year":"2004","unstructured":"Marshall HE, Hess DT, Stamler JS: S-nitrosylation: physiological regulation of NF-kappaB. Proc Natl Acad Sci U S A. 2004, 101: 8841-8842. 10.1073\/pnas.0403034101.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"454_CR39","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1038\/nrd2466","volume":"7","author":"JO Lundberg","year":"2008","unstructured":"Lundberg JO, Weitzberg E, Gladwin MT: The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics. Nat Rev Drug Discov. 2008, 7: 156-167. 10.1038\/nrd2466.","journal-title":"Nat Rev Drug Discov"},{"key":"454_CR40","doi-asserted-by":"publisher","first-page":"1543","DOI":"10.1378\/chest.122.5.1543","volume":"122","author":"W Mattos","year":"2002","unstructured":"Mattos W, Lim S, Russell R, Jatakanon A, Chung KF, Barnes PJ: Matrix metalloproteinase-9 expression in asthma: effect of asthma severity, allergen challenge, and inhaled corticosteroids. Chest. 2002, 122: 1543-1552. 10.1378\/chest.122.5.1543.","journal-title":"Chest"},{"key":"454_CR41","doi-asserted-by":"crossref","first-page":"6321","DOI":"10.4049\/jimmunol.163.11.6321","volume":"163","author":"S Ying","year":"1999","unstructured":"Ying S, Meng Q, Zeibecoglou K, Robinson DS, Macfarlane A, Humbert M, Kay AB: Eosinophil chemotactic chemokines (eotaxin, eotaxin-2, RANTES, monocyte chemoattractant protein-3 (MCP-3), and MCP-4), and C-C chemokine receptor 3 expression in bronchial biopsies from atopic and nonatopic (Intrinsic) asthmatics. J Immunol. 1999, 163: 6321-6329.","journal-title":"J Immunol"},{"key":"454_CR42","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1016\/S0891-5849(03)00406-4","volume":"35","author":"P Kleinbongard","year":"2003","unstructured":"Kleinbongard P, Dejam A, Lauer T, Rassaf T, Schindler A, Picker O, Scheeren T, Godecke A, Schrader J, Schulz R, Heusch G, Schaub GA, Bryan NS, Feelisch M, Kelm M: Plasma nitrite reflects constitutive nitric oxide synthase activity in mammals. Free Radic Biol Med. 2003, 35: 790-796. 10.1016\/S0891-5849(03)00406-4.","journal-title":"Free Radic Biol Med"},{"key":"454_CR43","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1111\/j.1748-1716.2006.01612.x","volume":"188","author":"IF Metzger","year":"2006","unstructured":"Metzger IF, Sertorio JT, Tanus-Santos JE: Relationship between systemic nitric oxide metabolites and cyclic GMP in healthy male volunteers. Acta Physiol (Oxf). 2006, 188: 123-127. 10.1111\/j.1748-1716.2006.01612.x.","journal-title":"Acta Physiol (Oxf)"},{"key":"454_CR44","doi-asserted-by":"publisher","first-page":"30667","DOI":"10.1074\/jbc.M705929200","volume":"282","author":"ZT Kelleher","year":"2007","unstructured":"Kelleher ZT, Matsumoto A, Stamler JS, Marshall HE: NOS2 regulation of NF-kappaB by S-nitrosylation of p65. J Biol Chem. 2007, 282: 30667-30672. 10.1074\/jbc.M705929200.","journal-title":"J Biol Chem"},{"key":"454_CR45","doi-asserted-by":"publisher","first-page":"24354","DOI":"10.1074\/jbc.M109.019919","volume":"284","author":"PC Sanghani","year":"2009","unstructured":"Sanghani PC, Davis WI, Fears SL, Green SL, Zhai L, Tang Y, Martin E, Bryan NS, Sanghani SP: Kinetic and cellular characterization of novel inhibitors of S-nitrosoglutathione reductase. J Biol Chem. 2009, 284: 24354-24362. 10.1074\/jbc.M109.019919.","journal-title":"J Biol Chem"},{"key":"454_CR46","doi-asserted-by":"publisher","first-page":"752","DOI":"10.1152\/japplphysiol.01302.2012","volume":"114","author":"Q Chen","year":"2013","unstructured":"Chen Q, Sievers RE, Varga M, Kharait S, Haddad DJ, Patton AK, Delany CS, Mutka SC, Blonder JP, Dube GP, Rosenthal GJ, Springer ML: Pharmacological inhibition of S-nitrosoglutathione reductase improves endothelial vasodilatory function in rats in vivo. J Appl Physiol. 2013, 114: 752-760. 10.1152\/japplphysiol.01302.2012.","journal-title":"J Appl Physiol"},{"key":"454_CR47","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1046\/j.1440-1711.2001.00990.x","volume":"79","author":"DH Yates","year":"2001","unstructured":"Yates DH: Role of exhaled nitric oxide in asthma. Immunol Cell Biol. 2001, 79: 178-190. 10.1046\/j.1440-1711.2001.00990.x.","journal-title":"Immunol Cell Biol"},{"key":"454_CR48","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/j.ejphar.2005.12.057","volume":"533","author":"FL Ricciardolo","year":"2006","unstructured":"Ricciardolo FL, Di SA, Sabatini F, Folkerts G: Reactive nitrogen species in the respiratory tract. Eur J Pharmacol. 2006, 533: 240-252. 10.1016\/j.ejphar.2005.12.057.","journal-title":"Eur J Pharmacol"},{"key":"454_CR49","doi-asserted-by":"publisher","first-page":"2480","DOI":"10.1021\/pr201180m","volume":"11","author":"MW Foster","year":"2012","unstructured":"Foster MW, Yang Z, Gooden DM, Thompson JW, Ball CH, Turner ME, Hou Y, Pi J, Moseley MA, Que L: Proteonomic characterization by S-nitrosogluthatione reductase inhibition. J Proteome Res. 2012, 11: 2480-2491. 10.1021\/pr201180m.","journal-title":"J Proteome Res"},{"key":"454_CR50","doi-asserted-by":"publisher","first-page":"L739","DOI":"10.1152\/ajplung.00134.2011","volume":"301","author":"MW Foster","year":"2011","unstructured":"Foster MW, Yang Z, Potts EN, Foster WM, Que LG: S-nitrosoglutathione supplementation to ovalbumin-sensitized and -challenged mice ameliorates methacholine-induced bronchoconstriction. Am J Physiol Lung Cell Mol Physiol. 2011, 301: L739-L744. 10.1152\/ajplung.00134.2011.","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"issue":"1","key":"454_CR51","first-page":"A6433","volume":"183","author":"JP Blonder","year":"2011","unstructured":"Blonder JP, Mutka SC, Drolet DW, Damaj B, Spicer D, Russell V, Sun X, Rosenthal GJ, Scoggin C: Oral S-nitrosoglutathione reductase inhibitors attenuate pulmonary inflammation and decrease airspace enlargement in experimental models of chornic obstructive pulmonary disease. Am J Respir Crit Care Med. 2011, 183 (1): A6433-A6433.","journal-title":"Am J Respir Crit Care Med"},{"key":"454_CR52","first-page":"P251","volume-title":"Advances in Inflammatory Bowel Diseases Crohn\u2019s & Colitis Foundations Clinical & Research Conference","author":"JP Blonder","year":"2011","unstructured":"Blonder JP, Mutka SC, Sun X, Drolet DW, Colagiovanni DB, Lyng G, Scoggin C, Rosenthal GJ: S-nitrosoglutathione reductase inhibitors for the prevention and treatment of experimental DSS colitis. Advances in Inflammatory Bowel Diseases Crohn\u2019s & Colitis Foundations Clinical & Research Conference. 2011, Imedex, LLC: Proceedings, P251-P251."},{"key":"454_CR53","first-page":"1","volume":"6","author":"AG Cox","year":"2013","unstructured":"Cox AG, Saunders DC, Kelsey PB, Conway AA, Tesmenitsky Y, Marchini JF, Brown KK, Stamler JS, Colagiovanni DB, Rosenthal GJ, Croce KJ, North TE, Goessling W: S-nitrosothiol signaling regulates liver development and improves outcome following toxic liver injury. Cell Reports. 2013, 6: 1-14.","journal-title":"Cell Reports"},{"key":"454_CR54","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1165\/ajrcmb.31.3.1","volume":"31","author":"J Bates","year":"2004","unstructured":"Bates J, Irvin C, Brusasco V, Drazen J, Fredberg J, Loring S, Eidelman D, Ludwig M, Macklem P, Martin J, Milic-Emili J, Hantos Z, Hyatt R, Lai-Fook S, Leff A, Solway J, Lutchen K, Suki B, Mitzner W, Pare P, Pride N, Sly P: The use and misuse of Penh in animal models of lung disease. Am J Respir Cell Mol Biol. 2004, 31: 373-374. 10.1165\/ajrcmb.31.3.1.","journal-title":"Am J Respir Cell Mol Biol"},{"key":"454_CR55","doi-asserted-by":"publisher","first-page":"L401","DOI":"10.1152\/ajplung.00027.2009","volume":"297","author":"JH Bates","year":"2009","unstructured":"Bates JH, Rincon M, Irvin CG: Animal models of asthma. Am J Physiol Lung Cell Mol Physiol. 2009, 297: L401-L410. 10.1152\/ajplung.00027.2009.","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"454_CR56","first-page":"11","volume":"476","author":"AG Pinder","year":"2008","unstructured":"Pinder AG, Rogers SC, Khalatbari A, Ingram TE, James PE: The measurement of nitric oxide and its metabolites in biological samples by ozone-based chemiluminescence. Methods Mol Biol. 2008, 476: 11-28.","journal-title":"Methods Mol Biol"},{"key":"454_CR57","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/1071576021000033112","volume":"37","author":"BK Yang","year":"2003","unstructured":"Yang BK, Vivas EX, Reiter CD, Gladwin MT: Methodologies for the sensitive and specific measurement of S-nitrosothiols, iron-nitrosyls, and nitrite in biological samples. Free Radic Res. 2003, 37: 1-10.","journal-title":"Free Radic Res"},{"key":"454_CR58","first-page":"3173","volume":"2013","author":"KA Broniowska","year":"1830","unstructured":"Broniowska KA, Diers AR, Hogg N: S-nitrosoglutathione. Biochim Biophys Acta. 1830, 2013: 3173-3181.","journal-title":"Biochim Biophys Acta"},{"key":"454_CR59","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1016\/j.molmed.2005.09.009","volume":"11","author":"EM Henderson","year":"2005","unstructured":"Henderson EM, Gaston B: SNOR and wheeze: the asthma enzyme?. Trends Mol Med. 2005, 11: 481-484. 10.1016\/j.molmed.2005.09.009.","journal-title":"Trends Mol Med"},{"key":"454_CR60","doi-asserted-by":"publisher","first-page":"2622","DOI":"10.1073\/pnas.051629498","volume":"98","author":"RA Dweik","year":"2001","unstructured":"Dweik RA, Comhair SA, Gaston B, Thunnissen FB, Farver C, Thomassen MJ, Kavuru M, Hammel J, Abu-Soud HM, Erzurum SC: NO chemical events in the human airway during the immediate and late antigen-induced asthmatic response. Proc Natl Acad Sci USA. 2001, 98: 2622-2627. 10.1073\/pnas.051629498.","journal-title":"Proc Natl Acad Sci USA"}],"container-title":["BMC Pulmonary Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2466-14-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2466-14-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2466-14-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2466-14-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,9]],"date-time":"2023-07-09T18:32:59Z","timestamp":1688927579000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcpulmmed.biomedcentral.com\/articles\/10.1186\/1471-2466-14-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,10]]},"references-count":60,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["454"],"URL":"https:\/\/doi.org\/10.1186\/1471-2466-14-3","relation":{},"ISSN":["1471-2466"],"issn-type":[{"value":"1471-2466","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,10]]},"article-number":"3"}}