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The study included patients with stable COPD and aged \u2265 40 years, evaluated in primary care. Data were collected relating to sociodemographic variables, clinical characteristics, quality of life (SF-12), severity of disease and treatment. The results obtained in men and women were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 10,711 patients (75.6% males and 24.4% females) were evaluated. Significant differences were found between males and females in relation to the following parameters: age (67.4 \u00b1 9.2 years in men vs 66.1 \u00b1 10.8 in women, p &lt; 0.05), smoking (91.9% of the men were smokers or ex-smokers vs 30% of the women), comorbidity (the frequency of hypertension, diabetes, anxiety and depression was greater in women, while ischemic heart disease was more common in men), mental component of quality of life (49.4 \u00b1 10.3 in men vs 44.6 \u00b1 11.9 in women, p &lt; 0.05) and severity of disease (56.5 \u00b1 13.3% in men vs 60.7 \u00b1 3.2 in women, p &lt; 0.05). As regards treatment, the percentage use of long-acting b<jats:sub>2<\/jats:sub>-adrenergic agonists, anticholinergic agents, theophyllines and mucolytic agents was significant greater in men. The total annual cost of COPD was greater in males than in females (1989.20 \u00b1 2364.47 \u20ac vs 1724.53 \u00b1 2106.90, p &lt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The women with COPD evaluated in this study were younger, smoked less and have more comorbidity, a poorer quality of life, and lesser disease severity than men with COPD. However, they generated a lesser total annual cost of COPD than men.<\/jats:p><\/jats:sec>","DOI":"10.1186\/1471-2466-9-2","type":"journal-article","created":{"date-parts":[[2009,1,2]],"date-time":"2009-01-02T19:13:35Z","timestamp":1230923615000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Characteristics of chronic obstructive pulmonary disease in Spain from a gender perspective"],"prefix":"10.1186","volume":"9","author":[{"given":"Pilar","family":"Carrasco-Garrido","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"de Miguel-D\u00edez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Rejas-Gutierrez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Mart\u00edn-Centeno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Gobartt-V\u00e1zquez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentin","family":"Hernandez-Barrera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angel Gil","family":"de Miguel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo","family":"Jimenez-Garcia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,1,2]]},"reference":[{"key":"120_CR1","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1136\/thorax.55.9.789","volume":"55","author":"JB Soriano","year":"2000","unstructured":"Soriano JB, Maier WC, Egger P, Visick G, Thakrar B, Sykes J, Pride NB: Recent trends in physician diagnosed COPD in women and men in the UK. 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