{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:20:37Z","timestamp":1787019637599,"version":"build-2736575974"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Urol"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1186\/1471-2490-13-70","type":"journal-article","created":{"date-parts":[[2013,12,6]],"date-time":"2013-12-06T05:03:23Z","timestamp":1386306203000},"source":"Crossref","is-referenced-by-count":10,"title":["Neuromodulation attenuates bladder hyperactivity in a rat cystitis model"],"prefix":"10.1186","volume":"13","author":[{"given":"Xin","family":"Su","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Nickles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dwight E","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,12,6]]},"reference":[{"key":"298_CR1","doi-asserted-by":"publisher","first-page":"1516","DOI":"10.1097\/00005392-199805000-00028","volume":"159","author":"HS Shaker","year":"1998","unstructured":"Shaker HS, Hassouna M: Sacral nerve root neuromodulation: an effective treatment for refractory urge incontinence. J Urol. 1998, 159: 1516-1519. 10.1097\/00005392-199805000-00028.","journal-title":"J Urol"},{"key":"298_CR2","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1111\/j.1464-410X.2005.05914.x","volume":"97","author":"FA Giuliano","year":"2006","unstructured":"Giuliano FA, Denys P, Chartier-Kastler E, Alexandre L, Bernabe J: L6-S1 spinal nerve stimulation reduces micturition frequency in anaesthetized rats with cyclophosphamide-induced cystitis. BJU Int. 2006, 97: 386-392. 10.1111\/j.1464-410X.2005.05914.x.","journal-title":"BJU Int"},{"key":"298_CR3","doi-asserted-by":"publisher","first-page":"F477","DOI":"10.1152\/ajprenal.00515.2011","volume":"302","author":"X Su","year":"2012","unstructured":"Su X, Nickles A, Nelson DE: Neuromodulation in a rat model of bladder micturition reflex. Am J Physiol Renal Physiol. 2012, 302: F477-F486. 10.1152\/ajprenal.00515.2011.","journal-title":"Am J Physiol Renal Physiol"},{"key":"298_CR4","doi-asserted-by":"publisher","first-page":"F1196","DOI":"10.1152\/ajprenal.00343.2012","volume":"303","author":"X Su","year":"2012","unstructured":"Su X, Nickles A, Nelson DE: Comparison of neural targets for neuromodulation of bladder micturition reflex in the rat. Am J Physiol Renal Physiol. 2012, 303: F1196-F1206. 10.1152\/ajprenal.00343.2012.","journal-title":"Am J Physiol Renal Physiol"},{"key":"298_CR5","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1111\/j.1464-410X.2011.10789.x","volume":"110","author":"AE Snellings","year":"2012","unstructured":"Snellings AE, Grill WM: Effects of stimulation site and stimulation parameters on bladder inhibition by electrical nerve stimulation. BJU Int. 2012, 110: 136-143. 10.1111\/j.1464-410X.2011.10789.x.","journal-title":"BJU Int"},{"key":"298_CR6","first-page":"38","volume-title":"International Pelvic Pain Society","author":"X Su","year":"2011","unstructured":"Su X, Nickles A, Nelson DE: Neuromodulation attenuates bladder irritation in a rat cystitis model [abstract]. International Pelvic Pain Society. 2011, 38-"},{"key":"298_CR7","first-page":"148","volume-title":"Society of Urodynamics, Female Pelvic Medicine & Urogenital Recontraction","author":"X Su","year":"2012","unstructured":"Su X, Nickles A, Nelson DE: Characterization of neuromodulation for bladder control in a rat cystitis model [abstract]. Society of Urodynamics, Female Pelvic Medicine & Urogenital Recontraction. 2012, 148-"},{"key":"298_CR8","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1186\/1471-2490-13-34","volume":"13","author":"X Su","year":"2013","unstructured":"Su X, Nickles A, Nelson DE: Quantification of effectiveness of bilateral and unilateral neuromodulation in the rat bladder rhythmic contraction model. BMC Urol. 2013, 13: 34-10.1186\/1471-2490-13-34.","journal-title":"BMC Urol"},{"key":"298_CR9","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1002\/nau.21108","volume":"30","author":"KE Andersson","year":"2011","unstructured":"Andersson KE, Soler R, F\u00fcllhase C: Rodent models for urodynamic investigation. Neurourol Urodyn. 2011, 30: 636-646. 10.1002\/nau.21108.","journal-title":"Neurourol Urodyn"},{"key":"298_CR10","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1016\/j.urology.2009.04.025","volume":"75","author":"K Hino","year":"2010","unstructured":"Hino K, Honjo H, Nakao M, Kitakoji H: The effects of sacral acupuncture on acetic acid-induced bladder irritation in conscious rats. Urol. 2010, 75: 730-734. 10.1016\/j.urology.2009.04.025.","journal-title":"Urol"},{"key":"298_CR11","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1152\/jn.1993.69.2.395","volume":"69","author":"HJ H\u00e4bler","year":"1993","unstructured":"H\u00e4bler HJ, J\u00e4nig W, Koltzenburg M: Receptive properties of myelinated primary afferents innervating the inflamed urinary bladder of the cat. J Neurophysiol. 1993, 69: 395-405.","journal-title":"J Neurophysiol"},{"key":"298_CR12","doi-asserted-by":"crossref","first-page":"2420","DOI":"10.1152\/jn.1994.72.5.2420","volume":"72","author":"JN Sengupta","year":"1994","unstructured":"Sengupta JN, Gebhart GF: Mechanosensitive properties of pelvic nerve afferent fibers innervating the urinary bladder of the rat. J Neurophysiol. 1994, 72: 2420-2430.","journal-title":"J Neurophysiol"},{"key":"298_CR13","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1152\/jn.1997.77.3.1566","volume":"77","author":"X Su","year":"1997","unstructured":"Su X, Sengupta JN, Gebhart GF: Effects of opioids on mechanosensitive pelvic nerve afferent fibers innervating the urinary bladder of the rat. J Neurophysiol. 1997, 77: 1566-1580.","journal-title":"J Neurophysiol"},{"key":"298_CR14","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1002\/nau.20612","volume":"28","author":"JR Vignes","year":"2009","unstructured":"Vignes JR, Deloire M, Petry K: Animal models of sacral neuromodulation for detrusor overactivity. Neurourol Urodyn. 2009, 28: 8-12. 10.1002\/nau.20612.","journal-title":"Neurourol Urodyn"},{"key":"298_CR15","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1046\/j.1464-410x.2000.00873.x","volume":"86","author":"Y Wang","year":"2000","unstructured":"Wang Y, Zhou Y, Mourad MS, Hassouna MM: Neuromodulation reduces urinary frequency in rats with hydrochloric acid-induced cystitis. BJU Int. 2000, 86: 726-730.","journal-title":"BJU Int"},{"key":"298_CR16","doi-asserted-by":"publisher","first-page":"900","DOI":"10.1111\/j.1464-410X.2005.05734.x","volume":"96","author":"SH Riazimand","year":"2005","unstructured":"Riazimand SH, Mense S: Interaction between neurotransmitter antagonists and effects of sacral neuromodulation in rats with chronically hyperactive bladder. BJU int. 2005, 96: 900-908. 10.1111\/j.1464-410X.2005.05734.x.","journal-title":"BJU int"},{"key":"298_CR17","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1046\/j.1464-410x.2000.00559.x","volume":"85","author":"H Shaker","year":"2000","unstructured":"Shaker H, Wang Y, Loung D, Balbaa L, Fehlings MG, Hassouna MM: Role of C-afferent fibers in the mechanism of action of sacral nerve root neuromodulation in chronic spinal cord injury. BJU Int. 2000, 85: 905-910.","journal-title":"BJU Int"},{"key":"298_CR18","doi-asserted-by":"publisher","first-page":"1966","DOI":"10.1016\/S0022-5347(05)67611-2","volume":"163","author":"Y Wang","year":"2000","unstructured":"Wang Y, Hassouna MM: Neuromodulation reduces c-fos gene expression in spinalized rats: a double-blind randomized study. J Urol. 2000, 163: 1966-1970. 10.1016\/S0022-5347(05)67611-2.","journal-title":"J Urol"},{"key":"298_CR19","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/S0022-4804(02)96481-4","volume":"107","author":"Y Zhou","year":"2002","unstructured":"Zhou Y, Wang Y, Abdelhady M, Mourad MS, Hassouna MM: Change of vanilloid receptor 1 following neuromodulation in rats with spinal cord injury. J Surg Res. 2002, 107: 140-144.","journal-title":"J Surg Res"},{"key":"298_CR20","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1002\/nau.20820","volume":"29","author":"CV Comiter","year":"2010","unstructured":"Comiter CV, Mazar C, Phull H, Salkini M: Chronic sacral nerve stimulation prevents detrusor structural and functional changes associated with bladder outlet obstruction-a rat model. Neurourol Urodyn. 2010, 29: 783-788. 10.1002\/nau.20820.","journal-title":"Neurourol Urodyn"},{"key":"298_CR21","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1111\/j.1464-410X.2007.07258.x","volume":"101","author":"PM Groenendijk","year":"2008","unstructured":"Groenendijk PM, Nyeholt AA L \u00e0, Heesakkers JP, Van Kerrebroeck PE, Hassouna MM, Gajewski JB, Cappellano F, Siegel SW, Fall M, Dijkema HE, Jonas U, Van Den Hombergh U: Urodynamic evaluation of sacral neuromodulation for urge urinary incontinence. BJU Int. 2008, 101: 325-329. 10.1111\/j.1464-410X.2007.07258.x.","journal-title":"BJU Int"},{"key":"298_CR22","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/0006-8993(84)91146-6","volume":"298","author":"T Hisamitsu","year":"1984","unstructured":"Hisamitsu T, De Groat WC: The inhibitory effect of opioid peptides and morphine applied intrathecally and intracerebroventricularly on the micturition reflex in the cat. Brain Res. 1984, 298: 51-65. 10.1016\/0006-8993(84)91146-6.","journal-title":"Brain Res"},{"key":"298_CR23","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1124\/jpet.108.138651","volume":"326","author":"LA Leon","year":"2008","unstructured":"Leon LA, Hoffman BE, Gardner SD, Laping NJ, Evans C, Lashinger ES, Su X: Effects of the \u03b23-adrenergic receptor agonist CL-316243 on bladder micturition reflex in spontaneously hypertensive rats. J Exp Phar Ther. 2008, 326: 178-185. 10.1124\/jpet.108.138651.","journal-title":"J Exp Phar Ther"},{"key":"298_CR24","doi-asserted-by":"publisher","first-page":"F585","DOI":"10.1152\/ajprenal.90273.2008","volume":"295","author":"X Su","year":"2008","unstructured":"Su X, Lashinger ES, Leon LA, Hoffman BE, Hieble JP, Gardner SD, Fries HE, Edwards RM, Li J, Laping NJ: An excitatory role for peripheral EP3 receptors in bladder afferent function. Am J Physiol Renal Physiol. 2008, 295: F585-F594. 10.1152\/ajprenal.90273.2008.","journal-title":"Am J Physiol Renal Physiol"},{"key":"298_CR25","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1093\/brain\/54.2.177","volume":"54","author":"FJF Barrington","year":"1931","unstructured":"Barrington FJF: The component reflexes of micturition in the cat. Parts I and II. Brain. 1931, 54: 177-188. 10.1093\/brain\/54.2.177.","journal-title":"Brain"},{"key":"298_CR26","first-page":"F53","volume":"305","author":"X Su","year":"2013","unstructured":"Su X, Nickles A, Nelson DE: The role of the endogenous opioid system in modulation of urinary bladder activity by spinal nerve stimulation. Am J Physiol Renal Physiol. 2013, 305: F53-F60.","journal-title":"Am J Physiol Renal Physiol"},{"key":"298_CR27","doi-asserted-by":"publisher","first-page":"2719","DOI":"10.1152\/jn.00700.2009","volume":"102","author":"C Tai","year":"2009","unstructured":"Tai C, Wang J, Jin T, Wang P, Kim SG, Roppolo JR, de Groat WC: Brain switch for reflex micturition control detected by FMRI in rats. J Neurophysiol. 2009, 102: 2719-2730. 10.1152\/jn.00700.2009.","journal-title":"J Neurophysiol"},{"key":"298_CR28","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/0165-1838(90)90256-I","volume":"30","author":"CA Maggi","year":"1990","unstructured":"Maggi CA, Conte B: Effect of urethane anesthesia on the micturition reflex in capsaicin-treated rats. J Auton Nerv Syst. 1990, 30: 247-251. 10.1016\/0165-1838(90)90256-I.","journal-title":"J Auton Nerv Syst"}],"container-title":["BMC Urology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2490-13-70\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2490-13-70.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2490-13-70","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2490-13-70.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,21]],"date-time":"2019-01-21T15:14:52Z","timestamp":1548083692000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcurol.biomedcentral.com\/articles\/10.1186\/1471-2490-13-70"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["298"],"URL":"https:\/\/doi.org\/10.1186\/1471-2490-13-70","relation":{},"ISSN":["1471-2490"],"issn-type":[{"value":"1471-2490","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12]]},"article-number":"70"}}