{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T04:16:51Z","timestamp":1728361011901},"reference-count":7,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2004,11,8]],"date-time":"2004-11-08T00:00:00Z","timestamp":1099872000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0\/"},{"start":{"date-parts":[[2004,11,8]],"date-time":"2004-11-08T00:00:00Z","timestamp":1099872000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Dermatol"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                        <jats:title>Background<\/jats:title>\n                        <jats:p>EMO syndrome, defined as a triad including exophthalmus, pretibial myxedema and osteoarthropathia, is a rare condition in patients suffering from hyperthyreosis.<\/jats:p>\n                     <\/jats:sec><jats:sec>\n                        <jats:title>Case presentation<\/jats:title>\n                        <jats:p>We here describe an interesting case of EMO syndrome associated with unilateral fibromatosis of the hand and an initial stage of generalized myxedema of the skin. To our knowledge a similar case has not yet been described in literature though reports about associated fibromatosis, e.g. located retroperitoneally, already exist. Familiar explanations include its initiation by autoimmune processes or aberrant T-cell cytokine stimulation leading to an overwhelming production of glycosaminoglycans.<\/jats:p>\n                     <\/jats:sec><jats:sec>\n                        <jats:title>Conclusion<\/jats:title>\n                        <jats:p>Interpreting our case in context with previous reports we conclude that associated fibromatosis induced by autoimmune processes may affect a variety of different localizations and therefore requires careful monitoring. A therapeutical attempt by using UVA1 irridation for pretibial myxedema remained without a satisfying regression.<\/jats:p>\n                     <\/jats:sec>","DOI":"10.1186\/1471-5945-4-17","type":"journal-article","created":{"date-parts":[[2004,11,11]],"date-time":"2004-11-11T07:29:58Z","timestamp":1100158198000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Fibromatosis of the hand associated with EMO syndrome: A Case report"],"prefix":"10.1186","volume":"4","author":[{"given":"Carolin","family":"Appelhans","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Breuckmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Bastian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Altmeyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Kreuter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2004,11,8]]},"reference":[{"key":"46_CR1","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1001\/archderm.1980.01640260081021","volume":"166","author":"DK Goette","year":"1980","unstructured":"Goette DK: Thyroid acropachy.\n                           Arch Dermatol 1980, 166: 205\u2013206. 10.1001\/archderm.116.2.205","journal-title":"Arch Dermatol"},{"key":"46_CR2","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1089\/105072501753211091","volume":"11","author":"H Niepomniszcze","year":"2001","unstructured":"Niepomniszcze H, Pitoia F, Goodall C, Manavela M, Bruno OD: Development of Graves' hyperthyroidism after radioiodine treatment for a toxic nodule: is the hyperthyroidism always triggered by 1311 therapy?\n                           Thyroid 2001, 11: 991. 10.1089\/105072501753211091","journal-title":"Thyroid"},{"key":"46_CR3","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1111\/j.1365-2133.1984.tb04642.x","volume":"110","author":"PM Farr","year":"1984","unstructured":"Farr PM, Ive FA: PUVA treatment of scleromyxoedema.\n                           Br J Dermatol 1984, 110: 347\u2013350.","journal-title":"Br J Dermatol"},{"key":"46_CR4","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1006\/clin.1994.1059","volume":"71","author":"TC Chang","year":"1994","unstructured":"Chang TC, Wu SL, Hsiao YL, Kuo ST, Chien LF, Kuo YF, Change CC, Chang TJ: TSH and TSH receptor antibody-binding sites in fibroblasts of pretibial myxedema are related to the extracellular domain of entire TSH receptor.\n                           Clin Immunol Immunopathol 1994, 71: 113\u2013120. 10.1006\/clin.1994.1059","journal-title":"Clin Immunol Immunopathol"},{"key":"46_CR5","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1089\/105072502760339415","volume":"12","author":"M Armigliato","year":"2002","unstructured":"Armigliato M, Paolini R, Bianchini E, Monesi G, Zamboni S, D'Andrea E: Hashimoto's thyroiditis and Graves' disease associated with retroperitoneal fibrosis.\n                           Thyroid 2002, 12: 829\u2013831. 10.1089\/105072502760339415","journal-title":"Thyroid"},{"key":"46_CR6","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1007\/s004170050227","volume":"237","author":"R van der Pol","year":"1999","unstructured":"van der Pol R, Nieuwenhuis MG, Mourits MP: Multifocal fibrosclerosis presenting as Grave's orbitopathy. Bilateral exophthalmos associated with retroperitoneal and sellar fibrosis.\n                           Graefes Arch Clin Exp Ophthalmol 1999, 237: 256\u2013258. 10.1007\/s004170050227","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"46_CR7","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1046\/j.1365-2133.2003.05261.x","volume":"148","author":"RS Dawe","year":"2003","unstructured":"Dawe RS: Ultraviolet A1 phototherapy.\n                           Br J Dermatol 2003, 148: 626\u2013637. 10.1046\/j.1365-2133.2003.05261.x","journal-title":"Br J Dermatol"}],"container-title":["BMC Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-5945-4-17.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/1471-5945-4-17\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-5945-4-17","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-5945-4-17.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T12:58:18Z","timestamp":1728305898000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcdermatol.biomedcentral.com\/articles\/10.1186\/1471-5945-4-17"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,11,8]]},"references-count":7,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2004,12]]}},"alternative-id":["46"],"URL":"https:\/\/doi.org\/10.1186\/1471-5945-4-17","relation":{},"ISSN":["1471-5945"],"issn-type":[{"type":"electronic","value":"1471-5945"}],"subject":[],"published":{"date-parts":[[2004,11,8]]},"assertion":[{"value":"6 April 2004","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 November 2004","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 November 2004","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"17"}}