{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T15:34:20Z","timestamp":1762875260648},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2009,10,18]],"date-time":"2009-10-18T00:00:00Z","timestamp":1255824000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Endocr Disord"],"published-print":{"date-parts":[[2009,12]]},"DOI":"10.1186\/1472-6823-9-22","type":"journal-article","created":{"date-parts":[[2009,10,20]],"date-time":"2009-10-20T06:15:45Z","timestamp":1256019345000},"source":"Crossref","is-referenced-by-count":28,"title":["Endogenous melatonin and oxidatively damaged guanine in DNA"],"prefix":"10.1186","volume":"9","author":[{"given":"Zoreh","family":"Davanipour","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik E","family":"Poulsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan","family":"Weimann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eugene","family":"Sobel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,10,18]]},"reference":[{"issue":"1","key":"81_CR1","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1111\/j.1600-079X.2006.00407.x","volume":"42","author":"DX Tan","year":"2007","unstructured":"Tan DX, Manchester LC, Terron MP, Flores LJ, Reiter RJ: One molecule, many derivatives: A never-ending interaction of melatonin with reactive oxygen and nitrogen species?. J Pineal Res. 2007, 42 (1): 28-42. 10.1111\/j.1600-079X.2006.00407.x.","journal-title":"J Pineal Res"},{"key":"81_CR2","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1007\/978-1-4615-4709-9_28","volume-title":"Tryptophan, Serotonin, and Melatonin: Basic Aspects and Applications","author":"GJM Maestroni","year":"1999","unstructured":"Maestroni GJM: Therapeutic potential of melatonin in immunodeficiency states, viral diseases, and cancer. Tryptophan, Serotonin, and Melatonin: Basic Aspects and Applications. Edited by: Heuther G. 1999, Kluwer Academic\/Plenum Publishers, New York, 217-226."},{"issue":"3-4","key":"81_CR3","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1159\/000014636","volume":"9","author":"RJ Reiter","year":"2000","unstructured":"Reiter RJ, Tan DX, Qi W, Manchester LC, Karbownik M, Calvo JR: Pharmacology and physiology of melatonin in the reduction of oxidative stress in vivo. Biol Signals Recept. 2000, 9 (3-4): 160-171. 10.1159\/000014636.","journal-title":"Biol Signals Recept"},{"issue":"1","key":"81_CR4","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/S1383-5742(00)00059-4","volume":"488","author":"S Kawanishi","year":"2001","unstructured":"Kawanishi S, Hiraku Y, Oikawa S: Mechanism of guanine-specific DNA damage by oxidative stress and its role in carcinogenesis and aging. Mutation Res. 2001, 488 (1): 65-76. 10.1016\/S1383-5742(00)00059-4.","journal-title":"Mutation Res"},{"issue":"2","key":"81_CR5","doi-asserted-by":"publisher","first-page":"E7","DOI":"10.1093\/nar\/30.2.e7","volume":"30","author":"A Weimann","year":"2002","unstructured":"Weimann A, Belling D, Poulsen HE: Quantification of 8-oxo-guanine and guanine as the nucleobase, nucleoside and deoxynucleoside forms in human urine by high-performance liquid chromatography-electrospray tandem mass spectrometry. Nucleic Acids Res. 2002, 30 (2): E7-10.1093\/nar\/30.2.e7.","journal-title":"Nucleic Acids Res"},{"issue":"1-2","key":"81_CR6","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.mrfmmm.2005.01.022","volume":"574","author":"MS Cooke","year":"2005","unstructured":"Cooke MS, Evans MD, Dove R, Rozalski R, Gackowski D, Siomet A, Lunec J, Olinski R: DNA repair is responsible for the presence of oxidatively damaged DNA lesions in urine. Mutat Res. 2005, 574 (1-2): 58-66.","journal-title":"Mutat Res"},{"issue":"1","key":"81_CR7","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1158\/1055-9965.EPI-07-0751","volume":"17","author":"MS Cooke","year":"2008","unstructured":"Cooke MS, Olinski R, Steffen for the European Standards Committee on Urinary DNA) Lesion Analysis (ESCULA): Measurement and meaning of oxidatively modified DNA lesions in urine. Cancer Epidemiol Biomarkers Prev. 2008, 17 (1): 3-14. 10.1158\/1055-9965.EPI-07-0751.","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"1-2","key":"81_CR8","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.jns.2007.08.041","volume":"266","author":"D Gackowski","year":"2008","unstructured":"Gackowski D, Rozalski R, Siomek A, Dziaman T, Nicpon K, Klimarczyk M, Araszkiewicz A, Olinski R: Oxidative stress and oxidative DNA damage is characteristic for mixed Alzheimer disease\/vascular dementia. J Neurol Sci. 2008, 266 (1-2): 57-62. 10.1016\/j.jns.2007.08.041.","journal-title":"J Neurol Sci"},{"issue":"5-6","key":"81_CR9","doi-asserted-by":"publisher","first-page":"1011","DOI":"10.1089\/ars.2006.8.1011","volume":"8","author":"R Olinski","year":"2006","unstructured":"Olinski R, Rozalski R, Gackowsk i D, Foksinski M, Siomek A, Cooke MS: Urinary measurement of 8-OxodG, 8-OxoGua, and 5HMUra a noninvasive assessment of oxidative damage to DNA. Antioxid Redox Signal. 2006, 8 (5-6): 1011-1019. 10.1089\/ars.2006.8.1011.","journal-title":"Antioxid Redox Signal"},{"issue":"1","key":"81_CR10","doi-asserted-by":"crossref","first-page":"133","DOI":"10.18388\/abp.1998_4328","volume":"45","author":"S Loft","year":"1998","unstructured":"Loft S, Poulsen HE: Estimation of oxidative DNA damage in man from urinary excretion of repair products. Acta Biochim Pol. 1998, 45 (1): 133-144.","journal-title":"Acta Biochim Pol"},{"issue":"5","key":"81_CR11","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1080\/10715760000300391","volume":"32","author":"MS Cooke","year":"2000","unstructured":"Cooke MS, Evans MD, Herbert KE, Lunee J: Urinary 8-hydroxy-2'-deoxyguanosine-source, significance and supplements. Free Radic Res. 2000, 32 (5): 381-397. 10.1080\/10715760000300391.","journal-title":"Free Radic Res"},{"issue":"1","key":"81_CR12","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1034\/j.1600-079x.2000.280106.x","volume":"28","author":"MR Cook","year":"2000","unstructured":"Cook MR, Graham C, Kavet R, Stevens RG, Davis S, Kheifets L: Morning urinary assessment of nocturnal melatonin secretion in older women. J Pineal Res. 2000, 28 (1): 41-47. 10.1034\/j.1600-079x.2000.280106.x.","journal-title":"J Pineal Res"},{"issue":"4","key":"81_CR13","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1111\/j.1600-079X.1998.tb00538.x","volume":"24","author":"C Graham","year":"1998","unstructured":"Graham C, Cook MR, Kavet R, Sastre A, Smith DK: Prediction of nocturnal plasma melatonin from morning urinary measures. J Pineal Res. 1998, 24 (4): 230-238. 10.1111\/j.1600-079X.1998.tb00538.x.","journal-title":"J Pineal Res"},{"issue":"6","key":"81_CR14","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1080\/10715769800300601","volume":"29","author":"HE Poulsen","year":"1998","unstructured":"Poulsen HE, Loft S, Prieme H, Vistisen K, Lykkesfeldt J, Nyyssonen K, Salonen JT: Oxidative DNA damage in vivo: relationship to age, plasma antioxidants, drug metabolism, glutathione-S-transferase activity and urinary creatinine excretion. Free Radic Res. 1998, 29 (6): 565-571. 10.1080\/10715769800300601.","journal-title":"Free Radic Res"},{"key":"81_CR15","unstructured":"SAS 9.1, 2002-2003. SAS Institute Inc., Cary, North Carolina"},{"issue":"6","key":"81_CR16","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1080\/10715769800300531","volume":"29","author":"B Halliwell","year":"1998","unstructured":"Halliwell B: Can oxidative DNA damage be used as a biomarker of cancer risk in humans? Problems, resolutions and preliminary results from nutritional supplementation studies. Free Rad Res. 1998, 29 (6): 469-486. 10.1080\/10715769800300531.","journal-title":"Free Rad Res"},{"issue":"4 Suppl 1","key":"81_CR17","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/S0090-4295(00)00959-6","volume":"57","author":"TL DeWeese","year":"2001","unstructured":"DeWeese TL, Hruszkewycz AM, Marnett LJ: Oxidative stress in chemoprevention trials. Urology. 2001, 57 (4 Suppl 1): 137-140. 10.1016\/S0090-4295(00)00959-6.","journal-title":"Urology"},{"issue":"1 Suppl Proceed","key":"81_CR18","doi-asserted-by":"publisher","first-page":"S40","DOI":"10.1016\/S1071-5576(00)00106-4","volume":"8","author":"HR Behrman","year":"2001","unstructured":"Behrman HR, Kodaman PH, Preston SL, Gao S: Oxidative stress and the ovary. J Soc Gynecol Investig. 2001, 8 (1 Suppl Proceedings): S40-S42. 10.1016\/S1071-5576(00)00106-4.","journal-title":"J Soc Gynecol Investig"},{"issue":"7","key":"81_CR19","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1177\/153537020222600718","volume":"226","author":"M Karbownik","year":"2001","unstructured":"Karbownik M, Reiter RJ, Burkhardt S, Gitto E, Tan DX, Lewi\u00f1ski A: Melatonin attenuates estradiol-induced oxidative damage to DNA: Relevance for cancer prevention. Exp Biol Med. 2001, 226 (7): 707-712.","journal-title":"Exp Biol Med"},{"key":"81_CR20","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1007\/978-1-4613-0381-7_48","volume":"398","author":"RJ Reiter","year":"1996","unstructured":"Reiter RJ: The indoleamine melatonin as a free radical scavenger, electron donor, and antioxidant: In vitro and in vivo studies. Adv Exp Med Biol. 1996, 398: 307-313.","journal-title":"Adv Exp Med Biol"},{"issue":"2","key":"81_CR21","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1016\/0003-9861(86)90305-X","volume":"246","author":"B Halliwell","year":"1986","unstructured":"Halliwell B, Gutteridge JM: Oxygen free radicals and iron in relation to biology and medicine: Some problems and concepts. Arch Biochem Biophys. 1986, 246 (2): 501-514. 10.1016\/0003-9861(86)90305-X.","journal-title":"Arch Biochem Biophys"},{"issue":"1","key":"81_CR22","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/S0024-3205(01)01097-9","volume":"69","author":"JW Clemens","year":"2001","unstructured":"Clemens JW, Jarzynika MJ, Witt-Enderby PA: Down-regulation of mt1 melatonin receptors in rat ovary following estrogen exposure. Life Sci. 2001, 69 (1): 27-35. 10.1016\/S0024-3205(01)01097-9.","journal-title":"Life Sci"},{"issue":"11","key":"81_CR23","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.1016\/S0006-2952(01)00615-3","volume":"61","author":"O Nosjean","year":"2001","unstructured":"Nosjean O, Nicolas JP, Klupsch , Delagrange P, Canet E, Boutin JA: Comparative pharmacological studies of melatonin receptors: MT1, MT2 and MT3\/QR2. Tissue distribution of MT3\/QR2. Biochem Pharmacol. 2001, 61 (11): 1369-1379. 10.1016\/S0006-2952(01)00615-3.","journal-title":"Biochem Pharmacol"},{"issue":"1","key":"81_CR24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1600-079X.1995.tb00133.x","volume":"18","author":"RJ Reiter","year":"1995","unstructured":"Reiter RJ, Melchiorri D, Sewerynek E, Poeggeler B, Barlow-Walden L, Chuang J, Ortiz GG, Acu\u00f1a-Castroviejo D: A review of the evidence supporting melatonin's role as an antioxidant. J Pineal Res. 1995, 18 (1): 1-11. 10.1111\/j.1600-079X.1995.tb00133.x.","journal-title":"J Pineal Res"},{"issue":"3-4","key":"81_CR25","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1159\/000014635","volume":"9","author":"DX Tan","year":"2000","unstructured":"Tan DX, Manchester LC, Reiter RJ, Qi WB, Karbownik M, Calvo JR: Significance of melatonin in antioxidant defense system: Reactions and products. Biol Signals Recept. 2000, 9 (3-4): 137-159. 10.1159\/000014635.","journal-title":"Biol Signals Recept"},{"issue":"2","key":"81_CR26","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1111\/j.1600-079X.1995.tb00147.x","volume":"18","author":"R Hardeland","year":"1995","unstructured":"Hardeland R, Balzer I, Poeggeler B, Fuhrberg B, Ur\u00eda H, Behrmann G, Wolf R, Meyer TJ, Reiter RJ: On the primary functions of melatonin in evolution: Mediation of photoperiodic signals in a unicell, photooxidation and scavenging of free radicals. J Pineal Res. 1995, 18 (2): 104-111. 10.1111\/j.1600-079X.1995.tb00147.x.","journal-title":"J Pineal Res"},{"issue":"4","key":"81_CR27","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1111\/j.1600-079X.1997.tb00353.x","volume":"23","author":"I Antolin","year":"1997","unstructured":"Antolin I, Obst B, Burkhardt S, Hardeland R: Antioxidative protection in a high-melatonin organism: The dinoflagellate Gonyaulax polydera is rescued from lethal oxidative stress by strongly elevated, but physiologically possible, concentrations of melatonin. J Pineal Res. 1997, 23 (4): 182-190. 10.1111\/j.1600-079X.1997.tb00353.x.","journal-title":"J Pineal Res"},{"issue":"1","key":"81_CR28","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1007\/BF02383723","volume":"232","author":"P Stasica","year":"1998","unstructured":"Stasica P, Ulanski P, Rosiak JM: Melatonin as a hydroxyl radical scavenger. J Radioanal Nucl Chem. 1998, 232 (1): 107-113. 10.1007\/BF02383723.","journal-title":"J Radioanal Nucl Chem"},{"issue":"1-2","key":"81_CR29","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1159\/000014571","volume":"8","author":"DX Tan","year":"1999","unstructured":"Tan DX, Manchester LC, Reiter RJ, Plummer BF: Cyclic 3-hydroxymelatonin: A melatonin metabolite generated as a result of hydroxyl radical scavenging. Biol Signals Recept. 1999, 8 (1-2): 70-74. 10.1159\/000014571.","journal-title":"Biol Signals Recept"},{"issue":"1","key":"81_CR30","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1034\/j.1600-079X.2002.01891.x","volume":"33","author":"FY Sun","year":"2002","unstructured":"Sun FY, Lin X, Mao LZ, Ge WH, Zhang LM, Huang YL, Gu J: Neuroprotection by melatonin against ischemic neuronal injury associated with modulation of DNA damage and repair in the rat following a transient cerebral ischemia. J Pineal Res. 2002, 33 (1): 48-56. 10.1034\/j.1600-079X.2002.01891.x.","journal-title":"J Pineal Res"},{"issue":"57","key":"81_CR31","doi-asserted-by":"publisher","first-page":"8675","DOI":"10.1038\/sj.onc.1205994","volume":"21","author":"T Stevnsner","year":"2002","unstructured":"Stevnsner T, Nyaga S, De Souza-Pinto NC, Horst van der GT, Gorgels TG, Hogue BA, Thorslund T, Bohr VA: Mitochondrial repair of 8-oxoguanine is deficient in Cockayne syndrome group B. Oncogene. 2002, 21 (57): 8675-8682. 10.1038\/sj.onc.1205994.","journal-title":"Oncogene"},{"issue":"17","key":"81_CR32","first-page":"6388","volume":"61","author":"M Jaiswal","year":"2001","unstructured":"Jaiswal M, LaRusso NF, Nishioka N, Nakabeppu Y, Gores GJ: Human Ogg1, a protein involved in the repair of 8-oxoguanine, is inhibited by nitric oxide. Cancer Res. 2001, 61 (17): 6388-6393.","journal-title":"Cancer Res"}],"container-title":["BMC Endocrine Disorders"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1472-6823-9-22\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1472-6823-9-22.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1472-6823-9-22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1472-6823-9-22.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,23]],"date-time":"2020-05-23T04:04:00Z","timestamp":1590206640000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcendocrdisord.biomedcentral.com\/articles\/10.1186\/1472-6823-9-22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10,18]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["81"],"URL":"https:\/\/doi.org\/10.1186\/1472-6823-9-22","relation":{},"ISSN":["1472-6823"],"issn-type":[{"value":"1472-6823","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,10,18]]},"article-number":"22"}}