{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T01:37:37Z","timestamp":1768268257648,"version":"3.49.0"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2014,3,25]],"date-time":"2014-03-25T00:00:00Z","timestamp":1395705600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Oral Health"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1186\/1472-6831-14-25","type":"journal-article","created":{"date-parts":[[2014,3,25]],"date-time":"2014-03-25T22:01:16Z","timestamp":1395784876000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Assessment of tissue oxygenation of periodontal inflammation in patients with coronary artery diseases using optical spectroscopy"],"prefix":"10.1186","volume":"14","author":[{"given":"Chunyang","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoming","family":"Xiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minqi","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael G","family":"Sowa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kan-Zhi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,3,25]]},"reference":[{"key":"364_CR1","doi-asserted-by":"publisher","first-page":"738","DOI":"10.1038\/nrendo.2011.106","volume":"7","author":"E Lalla","year":"2011","unstructured":"Lalla E, Papapanou PN: Diabetes mellitus and periodontitis: a tale of two common interrelated diseases. Nat Rev Endocrinol. 2011, 7: 738-748. 10.1038\/nrendo.2011.106.","journal-title":"Nat Rev Endocrinol"},{"key":"364_CR2","doi-asserted-by":"publisher","first-page":"2520","DOI":"10.1161\/CIR.0b013e31825719f3","volume":"125","author":"PB Lockhart","year":"2012","unstructured":"Lockhart PB, Bolger AF, Papapanou PN, Osinbowale O, Trevisan M, Levison ME, Lockhart PB, Bolger AF, Papapanou PN, Osinbowale O, Trevisan M, Levison ME, Taubert KA, Newburger JW, Gornik HL, Gewitz MH, Wilson WR, Smith SC, Baddour LM: Periodontal disease and atherosclerotic vascular disease: does the evidence support an independent association? A scientific statement from the American heart association. Circulation. 2012, 125: 2520-2544. 10.1161\/CIR.0b013e31825719f3.","journal-title":"Circulation"},{"key":"364_CR3","doi-asserted-by":"publisher","first-page":"2079","DOI":"10.1007\/s11606-008-0787-6","volume":"23","author":"LL Humphrey","year":"2008","unstructured":"Humphrey LL, Fu R, Buckley DI, Freeman M, Helfand M: Periodontal disease and coronary heart disease incidence: a systematic review and meta-analysis. J Gen Intern Med. 2008, 23: 2079-2086. 10.1007\/s11606-008-0787-6.","journal-title":"J Gen Intern Med"},{"key":"364_CR4","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1161\/01.STR.0000052974.79428.0C","volume":"34","author":"KJ Joshipura","year":"2003","unstructured":"Joshipura KJ, Hung HC, Rimm EB, Willett WC, Ascherio A: Periodontal disease, tooth loss, and incidence of ischemic stroke. Stroke. 2003, 34: 47-52. 10.1161\/01.STR.0000052974.79428.0C.","journal-title":"Stroke"},{"key":"364_CR5","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1016\/S0735-1097(00)01130-X","volume":"37","author":"TH Howell","year":"2001","unstructured":"Howell TH, Ridker PM, Ajani UA, Hennekens CH, Christen WG: Periodontal disease and risk of subsequent cardiovascular disease in U.S. male physicians. J Am Coll Cardiol. 2001, 37: 445-450. 10.1016\/S0735-1097(00)01130-X.","journal-title":"J Am Coll Cardiol"},{"key":"364_CR6","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/j.atherosclerosis.2012.01.026","volume":"222","author":"JH Southerland","year":"2012","unstructured":"Southerland JH, Moss K, Taylor GW, Beck JD, Pankow J, Gangula PR, Offenbacher S: Periodontitis and diabetes associations with measures of atherosclerosis and CHD. Atherosclerosis. 2012, 222: 196-201. 10.1016\/j.atherosclerosis.2012.01.026.","journal-title":"Atherosclerosis"},{"key":"364_CR7","doi-asserted-by":"publisher","first-page":"868","DOI":"10.1038\/nature01323","volume":"420","author":"P Libby","year":"2002","unstructured":"Libby P: Inflammation in atherosclerosis. Nature. 2002, 420: 868-874. 10.1038\/nature01323.","journal-title":"Nature"},{"key":"364_CR8","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1111\/j.1600-051X.2007.01173.x","volume":"35","author":"S Paraskevas","year":"2008","unstructured":"Paraskevas S, Huizinga JD, Loos BG: A systematic review and meta-analyses on C-reactive protein in relation to periodontitis. J Clin Periodontol. 2008, 35: 277-290. 10.1111\/j.1600-051X.2007.01173.x.","journal-title":"J Clin Periodontol"},{"key":"364_CR9","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/j.atherosclerosis.2010.07.025","volume":"213","author":"C Carallo","year":"2010","unstructured":"Carallo C, Fortunato L, de Franceschi MS, Irace C, Tripolino C, Cristofaro MG, Giudice M, Gnasso A: Periodontal disease and carotid atherosclerosis: are hemodynamic forces a link?. Atherosclerosis. 2010, 213: 263-267. 10.1016\/j.atherosclerosis.2010.07.025.","journal-title":"Atherosclerosis"},{"key":"364_CR10","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.1902\/jop.2003.74.8.1237","volume":"74","author":"GC Armitage","year":"2003","unstructured":"Armitage GC, Research, Science and Therapy Committee of the American Academy of Periodontology: Diagnosis of periodontal diseases. J Periodontol. 2003, 74: 1237-1247.","journal-title":"J Periodontol"},{"key":"364_CR11","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1902\/jop.1995.66.6.531","volume":"66","author":"G Greenstein","year":"1995","unstructured":"Greenstein G: Commentary on periodontal diagnostic testing. J Periodontol. 1995, 66: 531-535. 10.1902\/jop.1995.66.6.531.","journal-title":"J Periodontol"},{"issue":"7s","key":"364_CR12","doi-asserted-by":"publisher","first-page":"1365","DOI":"10.1902\/jop.2007.077002","volume":"78","author":"WV Giannobile","year":"2007","unstructured":"Giannobile WV: Periodontal surveillance \u2013 prospects for the future. J Periodontol. 2007, 78 (7s): 1365-10.1902\/jop.2007.077002.","journal-title":"J Periodontol"},{"key":"364_CR13","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1111\/j.1600-0765.2008.01112.x","volume":"44","author":"KZ Liu","year":"2009","unstructured":"Liu KZ, Xiang XM, Man A, Sowa MG, Cholakis A, Ghiabi E, Singer DL, Scott DA: In vivo determination of multiple indices of periodontal inflammation by optical spectroscopy. J Periodontal Res. 2009, 44: 117-124. 10.1111\/j.1600-0765.2008.01112.x.","journal-title":"J Periodontal Res"},{"key":"364_CR14","doi-asserted-by":"publisher","first-page":"511","DOI":"10.14219\/jada.archive.2000.0210","volume":"131","author":"LL Otis","year":"2000","unstructured":"Otis LL, Everett MJ, Sathyam US, Colston BW: Optical coherence tomography: a new imaging technology for dentistry. J Am Dent Assoc. 2000, 131: 511-514. 10.14219\/jada.archive.2000.0210.","journal-title":"J Am Dent Assoc"},{"key":"364_CR15","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1046\/j.1365-2591.2002.00458.x","volume":"35","author":"E Cotti","year":"2002","unstructured":"Cotti E, Campisi G, Garau V, Puddu G: A new technique for the study of periapical bone lesions: ultrasound real time imaging. Int Endod J. 2002, 35: 148-152. 10.1046\/j.1365-2591.2002.00458.x.","journal-title":"Int Endod J"},{"key":"364_CR16","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1902\/jop.2009.090419","volume":"81","author":"X Xiang","year":"2010","unstructured":"Xiang X, Sowa MG, Iacopino AM, Xiang X, Sowa MG, Iacopino AM, Maev RG, Hewko MD, Man A, Liu KZ: An update on novel non-invasive approaches for periodontal diagnosis. J Periodontol. 2010, 81: 186-198. 10.1902\/jop.2009.090419.","journal-title":"J Periodontol"},{"key":"364_CR17","doi-asserted-by":"publisher","first-page":"1161","DOI":"10.1902\/jop.2011.100632","volume":"82","author":"Z Ge","year":"2011","unstructured":"Ge Z, Liu KZ, Xiang X, Yang Q, Hui J, Kohlenberg E, Sowa MG: Assessment of local hemodynamics in periodontal inflammation using optical spectroscopy. J Periodontol. 2011, 82: 1161-1168. 10.1902\/jop.2011.100632.","journal-title":"J Periodontol"},{"key":"364_CR18","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1161\/01.CIR.0000047041.66447.29","volume":"107","author":"RJ Gibbons","year":"2003","unstructured":"Gibbons RJ, Abrams J, Chatterjee K, Daley J, Deedwania PC, Douglas JS, Ferguson TB, Fihn SD, Fraker TD, Gardin JM, O\u2019Rourke RA, Pasternak RC, Williams SV: A report of the American college of cardiology\/American heart association task force on practice guidelines (Committee on the management of patients with chronic stable angina). Circulation. 2003, 107: 149-158. 10.1161\/01.CIR.0000047041.66447.29.","journal-title":"Circulation"},{"key":"364_CR19","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/S0009-8981(01)00796-3","volume":"317","author":"MG Sowa","year":"2002","unstructured":"Sowa MG, Matas A, Schattka BJ, Mantsch HH: Spectroscopic assessment of cutaneous hemodynamics in the presence of high epidermal melanin concentration. Clin Chim Acta. 2002, 317: 203-212. 10.1016\/S0009-8981(01)00796-3.","journal-title":"Clin Chim Acta"},{"key":"364_CR20","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/j.2517-6161.1988.tb01738.x","volume":"50","author":"P Speckman","year":"1988","unstructured":"Speckman P: Kernel smoothing in partial linear models. J Royal Stat Soc: Ser B. 1988, 50: 413-436.","journal-title":"J Royal Stat Soc: Ser B"},{"key":"364_CR21","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1196\/annals.1384.028","volume":"1098","author":"JS Kinney","year":"2007","unstructured":"Kinney JS, Ramseier CA, Giannobile WV: Oral fluid-based biomarkers of alveolar bone loss in periodontitis. Ann N Y Acad Sci. 2007, 1098: 230-251. 10.1196\/annals.1384.028.","journal-title":"Ann N Y Acad Sci"},{"key":"364_CR22","doi-asserted-by":"publisher","first-page":"2063","DOI":"10.1902\/jop.2007.070210","volume":"78","author":"V Kwok","year":"2007","unstructured":"Kwok V, Caton JG: Commentary: prognosis revisited: a system for assigning periodontal prognosis. J Periodontol. 2007, 78: 2063-2071. 10.1902\/jop.2007.070210.","journal-title":"J Periodontol"},{"key":"364_CR23","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1111\/j.1600-0765.2011.01361.x","volume":"46","author":"G Nogueira-Filho","year":"2011","unstructured":"Nogueira-Filho G, Xiang XM, Shibli JA, Duarte PM, Sowa MG, Ferrari DS, Onuma T, DeCardoso LAG, Liu KZ: On site noninvasive assessment of peri-implant inflammation by optical spectroscopy. J Periodontal Res. 2011, 46: 382-388. 10.1111\/j.1600-0765.2011.01361.x.","journal-title":"J Periodontal Res"},{"key":"364_CR24","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1111\/j.1600-0765.1990.tb00898.x","volume":"25","author":"T Hanioka","year":"1990","unstructured":"Hanioka T, Shizukuishi S, Tsunemitsu A: Hemoglobin concentration and oxygen saturation of clinically healthy and inflamed gingiva in human subjects. J Periodontal Res. 1990, 25: 93-98. 10.1111\/j.1600-0765.1990.tb00898.x.","journal-title":"J Periodontal Res"},{"key":"364_CR25","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1128\/am.18.5.723-727.1969","volume":"18","author":"WJ Loesche","year":"1969","unstructured":"Loesche WJ: Oxygen sensitivity of various anaerobic bacteria. Appl Microbiol. 1969, 18: 723-727.","journal-title":"Appl Microbiol"},{"key":"364_CR26","doi-asserted-by":"publisher","first-page":"1196","DOI":"10.1177\/00220345880670090901","volume":"67","author":"A Amano","year":"1988","unstructured":"Amano A, Tamagawa H, Takagaki M, Murakami Y, Shizukuishi S, Tsunemitsu A: Relationship between enzyme activities involved in oxygen metabolism and oxygen tolerance in black-pigmented Bacteroides. J Dental Res. 1988, 67: 1196-1199. 10.1177\/00220345880670090901.","journal-title":"J Dental Res"},{"key":"364_CR27","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1161\/01.CIR.0000154582.37101.15","volume":"111","author":"M Desvarieux","year":"2005","unstructured":"Desvarieux M, Demmer RT, Rundek T, Desvarieux M, Demmer RT, Rundek T, Boden-Albala B, Jacobs DR, Sacco RL, Papapanou PN: Periodontal microbiota and carotid intima-media thickness: the oral infections and vascular disease epidemiology study (INVEST). Circulation. 2005, 111: 576-582. 10.1161\/01.CIR.0000154582.37101.15.","journal-title":"Circulation"},{"key":"364_CR28","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1001\/archinte.166.5.554","volume":"166","author":"A Spahr","year":"2006","unstructured":"Spahr A, Klein E, Khuseyinova N, Boeckh C, Muche R, Kunze M, Rothenbacher D, Pezeshki G, Hoffmeister A, Koenig W: Periodontal infections and coronary heart disease: role of periodontal bacteria and importance of total pathogen burden in the Coronary event and periodontal disease (CORODONT) study. Arch Intern Med. 2006, 166: 554-559. 10.1001\/archinte.166.5.554.","journal-title":"Arch Intern Med"},{"key":"364_CR29","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1111\/j.1600-0528.2010.00582.x","volume":"39","author":"O Andriankaja","year":"2011","unstructured":"Andriankaja O, Trevisan M, Falkner K, Dorn J, Hovey K, Sarikonda S, Mendoza T, Genco R: Association between periodontal pathogens and risk of nonfatal myocardial infarction. Community Dent Oral Epidemiol. 2011, 39: 177-185. 10.1111\/j.1600-0528.2010.00582.x.","journal-title":"Community Dent Oral Epidemiol"},{"key":"364_CR30","first-page":"1","volume":"30","author":"T Hanioka","year":"1990","unstructured":"Hanioka T, Amano A, Tamagawa H, Shizukuishi S: Evaluation of the depth sensitivity of tissue reflectance spectrophotometry in gingival measurement. J Osaka Univ Dent Sch. 1990, 30: 1-7.","journal-title":"J Osaka Univ Dent Sch"},{"key":"364_CR31","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1161\/01.STR.26.3.386","volume":"26","author":"GL Burke","year":"1995","unstructured":"Burke GL, Evans GW, Riley WA, Sharrett AR, Howard G, Barnes RW, Rosamond W, Crow RS, Rautaharju PM, Heiss G: Arterial wall thickness is associated with prevalent cardiovascular disease in middle-aged adults: the Atherosclerosis risk in communities (ARIC) study. Stroke. 1995, 26: 386-391. 10.1161\/01.STR.26.3.386.","journal-title":"Stroke"},{"key":"364_CR32","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1161\/01.ATV.11.5.1245","volume":"11","author":"JT Salonen","year":"1991","unstructured":"Salonen JT, Salonen R: Ultrasonographically assessed carotid morphology and the risk of coronary heart disease. Arterioscler Thromb. 1991, 11: 1245-1249. 10.1161\/01.ATV.11.5.1245.","journal-title":"Arterioscler Thromb"},{"key":"364_CR33","doi-asserted-by":"publisher","first-page":"1432","DOI":"10.1161\/01.CIR.96.5.1432","volume":"96","author":"ML Bots","year":"1997","unstructured":"Bots ML, Hoes AW, Koudstaal PJ, Hofman A, Grobbee DE: Common carotid intima-media thickness and risk of stroke and myocardial infarction: the Rotterdam study. Circulation. 1997, 96: 1432-1437. 10.1161\/01.CIR.96.5.1432.","journal-title":"Circulation"},{"key":"364_CR34","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1056\/NEJM199901073400103","volume":"340","author":"D O\u2019Leary","year":"1999","unstructured":"O\u2019Leary D, Polak J, Kronmal RA, Manolio T, Burke G, Wolfson SJ: Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults: cardiovascular health study collaborative research group. N Engl J Med. 1999, 340: 14-22. 10.1056\/NEJM199901073400103.","journal-title":"N Engl J Med"},{"key":"364_CR35","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1093\/oxfordjournals.aje.a010233","volume":"151","author":"L Chambless","year":"2000","unstructured":"Chambless L, Folsom A, Clegg L, Sharrett AR, Shahar E, Nieto FJ, Rosamond WD, Evans G: Carotid wall thickness is predictive of incident clinical stroke: the Atherosclerosis risk in communities study. Am J Epidemiol. 2000, 151: 478-487. 10.1093\/oxfordjournals.aje.a010233.","journal-title":"Am J Epidemiol"},{"key":"364_CR36","doi-asserted-by":"publisher","first-page":"1816","DOI":"10.1161\/hq1101.097803","volume":"21","author":"JD Beck","year":"2001","unstructured":"Beck JD, Elter JR, Heiss G, Couper D, Mauriello SM, Offenbacher S: Relationship of periodontal disease to carotid artery intima-media wall thickness: the atherosclerosis risk in communities (ARIC) study. Arterioscler Thromb Vasc Biol. 2001, 21: 1816-1822. 10.1161\/hq1101.097803.","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"364_CR37","doi-asserted-by":"publisher","first-page":"1196","DOI":"10.1096\/fj.08-119578","volume":"23","author":"S Piconi","year":"2009","unstructured":"Piconi S, Trabattoni D, Luraghi C, Perilli E, Borelli M, Pacei M, Rizzardini G, Lattuad A, Bray DH, Catalano M, Sparaco A, Clerici M: Treatment of periodontal disease results in improvements in endothelial dysfunction and reduction of the carotid intima\u2013media thickness. FASEB J. 2009, 23: 1196-1204. 10.1096\/fj.08-119578.","journal-title":"FASEB J"}],"container-title":["BMC Oral Health"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1472-6831-14-25.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1472-6831-14-25\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1472-6831-14-25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1472-6831-14-25.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,25]],"date-time":"2024-05-25T10:42:20Z","timestamp":1716633740000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcoralhealth.biomedcentral.com\/articles\/10.1186\/1472-6831-14-25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,25]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["364"],"URL":"https:\/\/doi.org\/10.1186\/1472-6831-14-25","relation":{},"ISSN":["1472-6831"],"issn-type":[{"value":"1472-6831","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,25]]},"assertion":[{"value":"7 January 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 March 2014","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 March 2014","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"25"}}