{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T20:57:07Z","timestamp":1776200227347,"version":"3.50.1"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2014,1,24]],"date-time":"2014-01-24T00:00:00Z","timestamp":1390521600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Women's Health"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1186\/1472-6874-14-17","type":"journal-article","created":{"date-parts":[[2014,1,24]],"date-time":"2014-01-24T03:01:12Z","timestamp":1390532472000},"source":"Crossref","is-referenced-by-count":21,"title":["Reproductive factors, intima media thickness and carotid plaques in a cross-sectional study of postmenopausal women enrolled in the population-based KORA F4 study"],"prefix":"10.1186","volume":"14","author":[{"given":"Doris","family":"St\u00f6ckl","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annette","family":"Peters","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Thorand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margit","family":"Heier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Koenig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jochen","family":"Seissler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joachim","family":"Thiery","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Rathmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christa","family":"Meisinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,1,24]]},"reference":[{"key":"379_CR1","doi-asserted-by":"publisher","first-page":"2580","DOI":"10.1093\/eurheartj\/ehl228","volume":"27","author":"C Lamina","year":"2006","unstructured":"Lamina C, Meisinger C, Heid IM, Lowel H, Rantner B, Koenig W, Kronenberg F: Association of ankle-brachial index and plaques in the carotid and femoral arteries with cardiovascular events and total mortality in a population-based study with 13 years of follow-up. Eur Heart J. 2006, 27: 2580-2587. 10.1093\/eurheartj\/ehl228.","journal-title":"Eur Heart J"},{"key":"379_CR2","doi-asserted-by":"publisher","first-page":"2053","DOI":"10.1016\/S0140-6736(12)60441-3","volume":"379","author":"MW Lorenz","year":"2012","unstructured":"Lorenz MW, Polak JF, Kavousi M, Mathiesen EB, Volzke H, Tuomainen TP, Sander D, Plichart M, Catapano AL, Robertson CM, et al: Carotid intima-media thickness progression to predict cardiovascular events in the general population (the PROG-IMT collaborative project): a meta-analysis of individual participant data. Lancet. 2012, 379: 2053-2062. 10.1016\/S0140-6736(12)60441-3.","journal-title":"Lancet"},{"key":"379_CR3","doi-asserted-by":"publisher","first-page":"e000087","DOI":"10.1161\/JAHA.113.000087","volume":"2","author":"JF Polak","year":"2013","unstructured":"Polak JF, Szklo M, Kronmal RA, Burke GL, Shea S, Zavodni AE, O'Leary DH: The value of carotid artery plaque and intima-media thickness for incident cardiovascular disease: the multi-ethnic study of atherosclerosis. J Am Heart Assoc. 2013, 2: e000087.","journal-title":"J Am Heart Assoc"},{"key":"379_CR4","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1056\/NEJMoa1012592","volume":"365","author":"JF Polak","year":"2011","unstructured":"Polak JF, Pencina MJ, Pencina KM, O'Donnell CJ, Wolf PA, D'Agostino RB: Carotid-wall intima-media thickness and cardiovascular events. N Engl J Med. 2011, 365: 213-221. 10.1056\/NEJMoa1012592.","journal-title":"N Engl J Med"},{"key":"379_CR5","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/j.atherosclerosis.2011.06.044","volume":"220","author":"Y Inaba","year":"2012","unstructured":"Inaba Y, Chen JA, Bergmann SR: Carotid plaque, compared with carotid intima-media thickness, more accurately predicts coronary artery disease events: a meta-analysis. Atherosclerosis. 2012, 220: 128-133. 10.1016\/j.atherosclerosis.2011.06.044.","journal-title":"Atherosclerosis"},{"key":"379_CR6","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1159\/000176899","volume":"86","author":"M Gerhard","year":"1995","unstructured":"Gerhard M, Baum P, Raby KE: Peripheral arterial-vascular disease in women: prevalence, prognosis, and treatment. Cardiology. 1995, 86: 349-355. 10.1159\/000176899.","journal-title":"Cardiology"},{"key":"379_CR7","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1007\/s00125-011-2410-3","volume":"55","author":"D St\u00f6ckl","year":"2012","unstructured":"St\u00f6ckl D, D\u00f6ring A, Peters A, Thorand B, Heier M, Huth C, St\u00f6ckl H, Rathmann W, Kowall B, Meisinger C: Age at menarche is associated with prediabetes and diabetes in women (aged 32-81\u00a0years) from the general population: the KORA F4 Study. Diabetologia. 2012, 55: 681-688. 10.1007\/s00125-011-2410-3.","journal-title":"Diabetologia"},{"key":"379_CR8","doi-asserted-by":"publisher","first-page":"4953","DOI":"10.1210\/jc.2009-1789","volume":"94","author":"R Lakshman","year":"2009","unstructured":"Lakshman R, Forouhi NG, Sharp SJ, Luben R, Bingham SA, Khaw KT, Wareham NJ, Ong KK: Early age at menarche associated with cardiovascular disease and mortality. J Clin Endocrinol Metab. 2009, 94: 4953-4960. 10.1210\/jc.2009-1789.","journal-title":"J Clin Endocrinol Metab"},{"key":"379_CR9","doi-asserted-by":"publisher","first-page":"e26076","DOI":"10.1371\/journal.pone.0026076","volume":"6","author":"D St\u00f6ckl","year":"2011","unstructured":"St\u00f6ckl D, Meisinger C, Peters A, Thorand B, Huth C, Heier M, Rathmann W, Kowall B, St\u00f6ckl H, D\u00f6ring A: Age at menarche and its association with the metabolic syndrome and its components: results from the KORA F4 study. PLoS One. 2011, 6: e26076-10.1371\/journal.pone.0026076.","journal-title":"PLoS One"},{"key":"379_CR10","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.ahj.2009.11.017","volume":"159","author":"NI Parikh","year":"2010","unstructured":"Parikh NI, Cnattingius S, Dickman PW, Mittleman MA, Ludvigsson JF, Ingelsson E: Parity and risk of later-life maternal cardiovascular disease. Am Heart J. 2010, 159: 215-221. 10.1016\/j.ahj.2009.11.017. e216","journal-title":"Am Heart J"},{"key":"379_CR11","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1089\/jwh.2006.15.763","volume":"15","author":"A Cohen","year":"2006","unstructured":"Cohen A, Pieper CF, Brown AJ, Bastian LA: Number of children and risk of metabolic syndrome in women. J Womens Health (Larchmt). 2006, 15: 763-773. 10.1089\/jwh.2006.15.763.","journal-title":"J Womens Health (Larchmt)"},{"key":"379_CR12","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/j.ajog.2009.03.031","volume":"201","author":"EP Gunderson","year":"2009","unstructured":"Gunderson EP, Jacobs DR, Chiang V, Lewis CE, Tsai A, Quesenberry CP, Sidney S: Childbearing is associated with higher incidence of the metabolic syndrome among women of reproductive age controlling for measurements before pregnancy: the CARDIA study. Am J Obstet Gynecol. 2009, 201: 177-e171-179","journal-title":"Am J Obstet Gynecol"},{"issue":"4","key":"379_CR13","doi-asserted-by":"publisher","first-page":"447","DOI":"10.7326\/0003-4819-85-4-447","volume":"85","author":"WB Kannel","year":"1976","unstructured":"Kannel WB, Hjortland MC, McNamara PM, Gordon T: Menopause and risk of cardiovascular disease: the Framingham study. Ann Intern Med. 1976, 85 (4): 447-52. 10.7326\/0003-4819-85-4-447.","journal-title":"Ann Intern Med"},{"key":"379_CR14","doi-asserted-by":"publisher","first-page":"211","DOI":"10.7326\/0003-4819-152-4-201002160-00005","volume":"152","author":"S Toh","year":"2010","unstructured":"Toh S, Hernandez-Diaz S, Logan R, Rossouw JE, Hernan MA: Coronary heart disease in postmenopausal recipients of estrogen plus progestin therapy: does the increased risk ever disappear? A randomized trial. Ann Intern Med. 2010, 152: 211-217. 10.7326\/0003-4819-152-4-201002160-00005.","journal-title":"Ann Intern Med"},{"key":"379_CR15","doi-asserted-by":"publisher","first-page":"2591","DOI":"10.1056\/NEJMoa071513","volume":"356","author":"JE Manson","year":"2007","unstructured":"Manson JE, Allison MA, Rossouw JE, Carr JJ, Langer RD, Hsia J, Kuller LH, Cochrane BB, Hunt JR, Ludlam SE, et al: Estrogen therapy and coronary-artery calcification. N Engl J Med. 2007, 356: 2591-2602. 10.1056\/NEJMoa071513.","journal-title":"N Engl J Med"},{"key":"379_CR16","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1080\/00016340701464374","volume":"86","author":"E Kharazmi","year":"2007","unstructured":"Kharazmi E, Moilanen L, Fallah M, Kaaja R, Kattainen A, Kahonen M, Jula A, Kesaniemi A, Luoto R: Reproductive history and carotid intima-media thickness. Acta Obstet Gynecol Scand. 2007, 86: 995-1002. 10.1080\/00016340701464374.","journal-title":"Acta Obstet Gynecol Scand"},{"key":"379_CR17","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1097\/gme.0b013e3181e5046d","volume":"18","author":"E Ozkaya","year":"2011","unstructured":"Ozkaya E, Cakir E, Okuyan E, Cakir C, Ustun G, Kucukozkan T: Comparison of the effects of surgical and natural menopause on carotid intima media thickness, osteoporosis, and homocysteine levels. Menopause. 2011, 18: 73-76. 10.1097\/gme.0b013e3181e5046d.","journal-title":"Menopause"},{"key":"379_CR18","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1097\/gme.0b013e3181fa27fd","volume":"18","author":"RC Thurston","year":"2011","unstructured":"Thurston RC, Sutton-Tyrrell K, Everson-Rose SA, Hess R, Powell LH, Matthews KA: Hot flashes and carotid intima media thickness among midlife women. Menopause. 2011, 18: 352-358. 10.1097\/gme.0b013e3181fa27fd.","journal-title":"Menopause"},{"key":"379_CR19","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/j.ijgo.2010.12.020","volume":"113","author":"E Ozkaya","year":"2011","unstructured":"Ozkaya E, Cakir E, Kara F, Okuyan E, Cakir C, Ustun G, Kucukozkan T: Impact of hot flashes and night sweats on carotid intima-media thickness and bone mineral density among postmenopausal women. Int J Gynaecol Obstet. 2011, 113: 235-238. 10.1016\/j.ijgo.2010.12.020.","journal-title":"Int J Gynaecol Obstet"},{"key":"379_CR20","doi-asserted-by":"publisher","first-page":"1199","DOI":"10.1210\/jc.2009-2262","volume":"95","author":"A Bechlioulis","year":"2010","unstructured":"Bechlioulis A, Kalantaridou SN, Naka KK, Chatzikyriakidou A, Calis KA, Makrigiannakis A, Papanikolaou O, Kaponis A, Katsouras C, Georgiou I, et al: Endothelial function, but not carotid intima-media thickness, is affected early in menopause and is associated with severity of hot flushes. J Clin Endocrinol Metab. 2010, 95: 1199-1206. 10.1210\/jc.2009-2262.","journal-title":"J Clin Endocrinol Metab"},{"key":"379_CR21","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1161\/01.STR.0000162712.27799.20","volume":"36","author":"B Wolff","year":"2005","unstructured":"Wolff B, Volzke H, Robinson D, Schwahn C, Ludemann J, Kessler C, John U, Felix SB: Relation of parity with common carotid intima-media thickness among women of the study of health in Pomerania. Stroke. 2005, 36: 938-943. 10.1161\/01.STR.0000162712.27799.20.","journal-title":"Stroke"},{"key":"379_CR22","doi-asserted-by":"publisher","first-page":"1332","DOI":"10.1161\/STROKEAHA.110.579219","volume":"41","author":"MR Skilton","year":"2010","unstructured":"Skilton MR, Bonnet F, Begg LM, Juonala M, Kahonen M, Lehtimaki T, Viikari JS, Raitakari OT: Childbearing, child-rearing, cardiovascular risk factors, and progression of carotid intima-media thickness: the Cardiovascular Risk in Young Finns study. Stroke. 2010, 41: 1332-1337. 10.1161\/STROKEAHA.110.579219.","journal-title":"Stroke"},{"key":"379_CR23","doi-asserted-by":"publisher","first-page":"2259","DOI":"10.1161\/hs1001.097224","volume":"32","author":"KH Humphries","year":"2001","unstructured":"Humphries KH, Westendorp IC, Bots ML, Spinelli JJ, Carere RG, Hofman A, Witteman JC: Parity and carotid artery atherosclerosis in elderly women: the Rotterdam study. Stroke. 2001, 32: 2259-2264. 10.1161\/hs1001.097224.","journal-title":"Stroke"},{"key":"379_CR24","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1001\/archinte.162.1.82","volume":"162","author":"C Meisinger","year":"2002","unstructured":"Meisinger C, Thorand B, Schneider A, Stieber J, Doring A, Lowel H: Sex differences in risk factors for incident type 2 diabetes mellitus: the MONICA Augsburg cohort study. Arch Intern Med. 2002, 162: 82-89. 10.1001\/archinte.162.1.82.","journal-title":"Arch Intern Med"},{"key":"379_CR25","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1016\/j.atherosclerosis.2013.01.035","volume":"228","author":"D St\u00f6ckl","year":"2013","unstructured":"St\u00f6ckl D, D\u00f6ring A, Thorand B, Heier M, Peters A, Lamina C, Kronenberg F, Meisinger C: Reproductive factors and its association with peripheral arterial disease in women aged 52-81\u00a0years: the KORA F4 study. Atherosclerosis. 2013, 228: 224-229. 10.1016\/j.atherosclerosis.2013.01.035.","journal-title":"Atherosclerosis"},{"key":"379_CR26","doi-asserted-by":"publisher","first-page":"e52590","DOI":"10.1371\/journal.pone.0052590","volume":"7","author":"B Kowall","year":"2012","unstructured":"Kowall B, Ebert N, Then C, Thiery J, Koenig W, Meisinger C, Rathmann W, Seissler J: Associations between blood glucose and carotid intima-media thickness disappear after adjustment for shared risk factors: the KORA F4 study. PLoS One. 2012, 7: e52590-10.1371\/journal.pone.0052590.","journal-title":"PLoS One"},{"key":"379_CR27","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1089\/15246090050020682","volume":"9","author":"ST Yeh","year":"2000","unstructured":"Yeh ST, Morton DJ, Barrett-Connor E: Lower extremity arterial disease in older women: the Rancho Bernardo study. J Womens Health Gend Based Med. 2000, 9: 373-380. 10.1089\/15246090050020682.","journal-title":"J Womens Health Gend Based Med"},{"key":"379_CR28","doi-asserted-by":"publisher","first-page":"1449","DOI":"10.1161\/CIR.0b013e31824c39ba","volume":"125","author":"AT Hirsch","year":"2012","unstructured":"Hirsch AT, Allison MA, Gomes AS, Corriere MA, Duval S, Ershow AG, Hiatt WR, Karas RH, Lovell MB, McDermott MM, et al: A call to action: women and peripheral artery disease: a scientific statement from the American Heart Association. Circulation. 2012, 125: 1449-1472. 10.1161\/CIR.0b013e31824c39ba.","journal-title":"Circulation"},{"key":"379_CR29","doi-asserted-by":"publisher","first-page":"1876","DOI":"10.1056\/NEJMoa1010112","volume":"365","author":"M Juonala","year":"2011","unstructured":"Juonala M, Magnussen CG, Berenson GS, Venn A, Burns TL, Sabin MA, Srinivasan SR, Daniels SR, Davis PH, Chen W, et al: Childhood adiposity, adult adiposity, and cardiovascular risk factors. N Engl J Med. 2011, 365: 1876-1885. 10.1056\/NEJMoa1010112.","journal-title":"N Engl J Med"},{"key":"379_CR30","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1093\/aje\/kws473","volume":"178","author":"L Fernandez-Rhodes","year":"2013","unstructured":"Fernandez-Rhodes L, Demerath EW, Cousminer DL, Tao R, Dreyfus JG, Esko T, Smith AV, Gudnason V, Harris TB, Launer L, et al: Association of adiposity genetic variants with menarche timing in 92,105 women of European descent. Am J Epidemiol. 2013, 178: 451-460. 10.1093\/aje\/kws473.","journal-title":"Am J Epidemiol"},{"key":"379_CR31","doi-asserted-by":"publisher","first-page":"1445","DOI":"10.1016\/j.fertnstert.2011.09.010","volume":"96","author":"A Gompel","year":"2011","unstructured":"Gompel A, Boutouyrie P, Joannides R, Christin-Maitre S, Kearny-Schwartz A, Kunz K, Laurent S, Boivin JM, Pannier B, Pornel B, et al: Association of menopause and hormone replacement therapy with large artery remodeling. Fertil Steril. 2011, 96: 1445-1450. 10.1016\/j.fertnstert.2011.09.010.","journal-title":"Fertil Steril"},{"key":"379_CR32","doi-asserted-by":"publisher","first-page":"1385","DOI":"10.1016\/j.fertnstert.2012.11.053","volume":"99","author":"EF Wolff","year":"2013","unstructured":"Wolff EF, He Y, Black DM, Brinton EA, Budoff MJ, Cedars MI, Hodis HN, Lobo RA, Manson JE, Merriam GR, et al: Self-reported menopausal symptoms, coronary artery calcification, and carotid intima-media thickness in recently menopausal women screened for the Kronos early estrogen prevention study (KEEPS). Fertil Steril. 2013, 99: 1385-1391. 10.1016\/j.fertnstert.2012.11.053.","journal-title":"Fertil Steril"},{"key":"379_CR33","doi-asserted-by":"publisher","first-page":"1469","DOI":"10.1016\/S0002-9149(97)00738-8","volume":"80","author":"JF Clapp 3rd","year":"1997","unstructured":"Clapp JF, Capeless E: Cardiovascular function before, during, and after the first and subsequent pregnancies. Am J Cardiol. 1997, 80: 1469-1473. 10.1016\/S0002-9149(97)00738-8.","journal-title":"Am J Cardiol"},{"key":"379_CR34","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1016\/j.atherosclerosis.2011.08.031","volume":"219","author":"L Conde","year":"2011","unstructured":"Conde L, Bevan S, Sitzer M, Klopp N, Illig T, Thiery J, Seissler J, Baumert J, Raitakari O, Kahonen M, et al: Novel associations for coronary artery disease derived from genome wide association studies are not associated with increased carotid intima-media thickness, suggesting they do not act via early atherosclerosis or vessel remodeling. Atherosclerosis. 2011, 219: 684-689. 10.1016\/j.atherosclerosis.2011.08.031.","journal-title":"Atherosclerosis"}],"container-title":["BMC Women's Health"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1472-6874-14-17\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1472-6874-14-17.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1472-6874-14-17","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1472-6874-14-17.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,23]],"date-time":"2019-01-23T00:23:37Z","timestamp":1548203017000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcwomenshealth.biomedcentral.com\/articles\/10.1186\/1472-6874-14-17"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,24]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["379"],"URL":"https:\/\/doi.org\/10.1186\/1472-6874-14-17","relation":{},"ISSN":["1472-6874"],"issn-type":[{"value":"1472-6874","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,24]]},"article-number":"17"}}