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These plants have been used as traditional medicines by local ethnic groups, where they are prepared as decoction, pastes for wound infections, and some have been eaten as salad. This paper focused on the assessment of antioxidant potential, antibacterial activity and classes of phytochemicals of nine plants from the Leguminosae family.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>\n              <jats:italic>Acacia auriculiformis<\/jats:italic>, <jats:italic>Bauhinia kockiana<\/jats:italic>, <jats:italic>Bauhinia purpurea<\/jats:italic>, <jats:italic>Caesalpinia pulcherrima<\/jats:italic>, <jats:italic>Calliandra tergemina<\/jats:italic>, <jats:italic>Cassia surattensis, Leucaena leucocephala<\/jats:italic>, <jats:italic>Peltophorum pterocarpum<\/jats:italic>, and <jats:italic>Samanea saman<\/jats:italic> were extracted with aqueous methanol and dichloromethane:methanol mixture to test for antioxidant and antibacterial activities. The Folin-Ciocalteu assay was conducted to quantify the total phenolic content and 2, 2-diphenyl-1-picrylhydrazyl (DPPH) assay was used to determine the free radical quenching capacity. Antibacterial activity was assessed using disc diffusion (Kirby-Bauer) assay. Screening for major classes of phytochemical was done using standard chemical tests.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>\n              <jats:italic>B. kockiana<\/jats:italic> flowers and <jats:italic>C. pulcherrima<\/jats:italic> leaves contained high total phenolic content (TPC) and strong DPPH radical scavenging ability with TPC of 8280 \u00b1 498 mg GAE\/100 g, IC<jats:sub>50<\/jats:sub> of 27.0 \u00b1 5.0 \u03bcg\/mL and TPC of 5030 \u00b1 602 mg GAE\/100 g, IC<jats:sub>50<\/jats:sub> of 50.0 \u00b1 5.0 \u03bcg\/mL respectively. Positive correlation was observed between TPC and free radical scavenging ability. Most extracts showed antibacterial activity against Gram positive bacteria at 1 mg, while none showed activity against Gram negative bacteria at the same dose. All extracts (except <jats:italic>Samanea saman<\/jats:italic> flower) showed antibacterial activity against two strains of methicillin resistant <jats:italic>Staphylococcus aureus<\/jats:italic> (MRSA) with MID values ranging between 100 \u03bcg\/disc and 500 \u03bcg\/disc.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>The potential source of antioxidant and antibacterial agents, especially for MRSA infection treatments were found in <jats:italic>B. kockiana<\/jats:italic>, <jats:italic>C. pulcherrima<\/jats:italic>, <jats:italic>C. tergemina<\/jats:italic> and <jats:italic>P. pterocarpum<\/jats:italic>. These preliminary results would be a guide in the selection of potential candidates for further pharmacological study and in search of new drug candidate in treating MRSA infections.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1472-6882-11-12","type":"journal-article","created":{"date-parts":[[2011,2,10]],"date-time":"2011-02-10T02:16:58Z","timestamp":1297304218000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":115,"title":["Assessment of phytochemical content, polyphenolic composition, antioxidant and antibacterial activities of Leguminosae medicinal plants in Peninsular Malaysia"],"prefix":"10.1186","volume":"11","author":[{"given":"Yik Ling","family":"Chew","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elaine Wan","family":"Ling Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei Ling","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yau Yan","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johnson","family":"Stanslas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joo Kheng","family":"Goh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2011,2,10]]},"reference":[{"key":"369_CR1","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/1472-6882-10-15","volume":"10","author":"HY Lai","year":"2010","unstructured":"Lai HY, Lim YY, Kim KH: Blechnum Orientale Linn - a fern with potential as antioxidant, anticancer and antibacterial agent. 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