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Activity against the wall-less bacterial pathogen <jats:italic>Mycoplasma mycoides<\/jats:italic> subsp. <jats:italic>capri<\/jats:italic> was determined and compared to activities measured against <jats:italic>Escherichia coli<\/jats:italic> and <jats:italic>Bacillus subtilis<\/jats:italic>. Antimicrobial susceptibility testing was performed by broth microdilution assays. The lethal or inhibitory nature of each extract was determined by subculture into neat growth medium.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Growth of <jats:italic>M<\/jats:italic>. <jats:italic>mycoides capri<\/jats:italic>, <jats:italic>E<\/jats:italic>. <jats:italic>coli<\/jats:italic>, and <jats:italic>B<\/jats:italic>. <jats:italic>subtilis<\/jats:italic> was inhibited by elderberry extract, oregano oil, ethanol extract of oregano leaves, and ethanol extract of goldenseal root. No inhibition was seen with aqueous extract of astragalus or calendula oil. Growth of <jats:italic>M<\/jats:italic>. <jats:italic>mycoides capri<\/jats:italic> and <jats:italic>B<\/jats:italic>. <jats:italic>subtilis<\/jats:italic> was inhibited by ethanol extract of astragalus, whereas growth of <jats:italic>E<\/jats:italic>. <jats:italic>coli<\/jats:italic> was not. Similarly, <jats:italic>M<\/jats:italic>. <jats:italic>mycoides capri<\/jats:italic> and <jats:italic>E<\/jats:italic>. <jats:italic>coli<\/jats:italic> were inhibited by aqueous extract of thyme, but <jats:italic>B<\/jats:italic>. <jats:italic>subtilis<\/jats:italic> was unaffected. Only <jats:italic>B<\/jats:italic>. <jats:italic>subtilis<\/jats:italic> was inhibited by colloidal silver. Measured MICs ranged from 0.0003 mg\/mL to 3.8 mg\/mL. Bacteriostatic and bactericidal effects differed by species and extract.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>The atypical pathogen <jats:italic>M<\/jats:italic>. <jats:italic>mycoides capri<\/jats:italic> was sensitive to extracts from many medicinal plants commonly used as antimicrobials in states of preparation and concentrations currently available for purchase in the United States and Europe. Variation in bacteriostatic and bactericidal activities between species and extracts indicates that multiple effecter compounds are present in these plant species.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1472-6882-12-169","type":"journal-article","created":{"date-parts":[[2012,10,3]],"date-time":"2012-10-03T01:38:53Z","timestamp":1349228333000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["In Vitro efficacy of antimicrobial extracts against the atypical ruminant pathogen Mycoplasma mycoides subsp. capri"],"prefix":"10.1186","volume":"12","author":[{"given":"Amanda V","family":"Arjoon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte V","family":"Saylor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meghan","family":"May","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,10,2]]},"reference":[{"key":"1159_CR1","first-page":"535","volume-title":"Mycoplasmas: Molecular Biology, Pathogenicity, and Strategies for Control","author":"C B\u00e9b\u00e9ar","year":"2005","unstructured":"B\u00e9b\u00e9ar C, Kempf I: Antimicrobial Therapy and Antimicrobial Resistance. 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