{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,8]],"date-time":"2026-11-08T13:16:44Z","timestamp":1794143804649,"version":"4.8.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2013,10,16]],"date-time":"2013-10-16T00:00:00Z","timestamp":1381881600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Complement Altern Med"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1186\/1472-6882-13-267","type":"journal-article","created":{"date-parts":[[2013,10,16]],"date-time":"2013-10-16T13:03:40Z","timestamp":1381928620000},"source":"Crossref","is-referenced-by-count":84,"title":["Hypoglycemic effect of polysaccharides with different molecular weight of Pseudostellaria heterophylla"],"prefix":"10.1186","volume":"13","author":[{"given":"Juan","family":"Hu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wensheng","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinlong","family":"chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaowei","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenzhu","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohua","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,10,16]]},"reference":[{"issue":"1","key":"1515_CR1","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1111\/j.1463-1326.2012.01628.x","volume":"15","author":"JJ Holst","year":"2013","unstructured":"Holst JJ, Vilsb\u00a2II T: Combining GLP-1 receptor agonists with insulin: therapeutic rationales and clinical findings. Diabetes Obes Metab. 2013, 15 (1): 3-14. 10.1111\/j.1463-1326.2012.01628.x.","journal-title":"Diabetes Obes Metab"},{"key":"1515_CR2","first-page":"1","volume":"76","author":"JG Fang","year":"2013","unstructured":"Fang JG, Wei HK, Sun YY, Zhang XD, Liu WY, Chang QT, Wang RH, Gong YW: Regulation of podocalyxin expression in the kidney of streptozotocin-induced diabetic rats with Chinese herbs (Yishen capsule). BMC Complement Altern Med. 2013, 76: 1-6.","journal-title":"BMC Complement Altern Med"},{"issue":"6","key":"1515_CR3","first-page":"621","volume":"29","author":"YJ Li","year":"2006","unstructured":"Li YJ, Xu HX: Research Progress on Anti\u2009\u00b7\u2009diabetic Chinese Medicines. Zhong Yao Cai. 2006, 29 (6): 621-625.","journal-title":"Zhong Yao Cai"},{"key":"1515_CR4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2013\/710892","volume":"104","author":"SJ Grant","year":"2013","unstructured":"Grant SJ, Chang DHT, Liu JX, Wong V, Kiat H, Bensoussan A: Chinese herbal medicine for impaired glucose tolerance: a randomized placebo controlled trial. BMC Complement Altern Med. 2013, 104: 1-8.","journal-title":"BMC Complement Altern Med"},{"key":"1515_CR5","first-page":"1","volume":"63","author":"CM Teugwa","year":"2013","unstructured":"Teugwa CM, Boudjeko T, Tchinda BT, Mejiato PC, Zofou D: Anti-hyperglycaemic globulins from selected Cucurbitaceae seeds used as antidiabetic medicinal plants in Africa. BMC Complement Altern Med. 2013, 63: 1-7.","journal-title":"BMC Complement Altern Med"},{"key":"1515_CR6","first-page":"1","volume":"52","author":"XY Guo","year":"2013","unstructured":"Guo XY, Yoshitomi H, Gao M, Qin LL, Duan Y, Sun W, Xu TH, Xie PF, Zhou JX, Huang LS, Liu TH: Guava leaf extracts promote glucose metabolism in SHRSP.Z-Leprfa\/Izm rats by improving insulin resistance in skeletal muscle. BMC Complement Altern Med. 2013, 52: 1-8.","journal-title":"BMC Complement Altern Med"},{"key":"1515_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2012\/847167","volume":"264","author":"W Pierre","year":"2012","unstructured":"Pierre W, Gildas AJH, Ulrich MC, Modeste W-N, Beno\u00eet NT, Albert K: Hypoglycemic and hypolipidemic effects of Bersama engleriana leaves in nicotinamide\/streptozotocin-induced type 2 diabetic rats. BMC Complement Altern Med. 2012, 264: 1-6.","journal-title":"BMC Complement Altern Med"},{"key":"1515_CR8","first-page":"1","volume":"2","author":"K Manya","year":"2012","unstructured":"Manya K, Champion B, Dunning T: The use of complementary and alternative medicine among people living with diabetes in Sydney. BMC Complement Altern Med. 2012, 2: 1-5.","journal-title":"BMC Complement Altern Med"},{"issue":"3","key":"1515_CR9","first-page":"159","volume":"31","author":"ZS Jiang","year":"2007","unstructured":"Jiang ZS, Ni Q, Zhou XZ, Xing WJ, Ling L, Liu BY: Study on drug law of Type 2 diabetes based on structured clinical information acquisition system. J Shandong University of TCM. 2007, 31 (3): 159-203.","journal-title":"J Shandong University of TCM"},{"issue":"21","key":"1515_CR10","first-page":"299","volume":"17","author":"WN Chen","year":"2011","unstructured":"Chen WN, Jiang M, Zheng G, Guo HT, Zhou Q, Lv AP: Exploring rules of Chinese patent medicines and Western medicines in treatment of type 2 diabetes with text mining. Chinese J Exp Tradit Med Formulae. 2011, 17 (21): 299-302.","journal-title":"Chinese J Exp Tradit Med Formulae"},{"issue":"11","key":"1515_CR11","first-page":"19","volume":"13","author":"Q Ni","year":"2006","unstructured":"Ni Q, Chen SB, Zhou XZ, Wei ZX, Gao YB, Li Y, Wang XM, Li P, Lin L, Liu BY: Study of relationship between formula (herbs) and syndrome about Type 2 diabetes mellitus affiliated metabolic syndrome based on free-scale networks. Chinese Journal of Information on TCM. 2006, 13 (11): 19-22.","journal-title":"Chinese Journal of Information on TCM"},{"issue":"1","key":"1515_CR12","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.jep.2009.09.055","volume":"127","author":"M Liu","year":"2010","unstructured":"Liu M, Wu K, Mao XQ, Wu Y, Ouyang JP: Astragalus polysaccharide improves insulin sensitivity in KKAy mice: Regulation of PKB\/GLUT4 signaling in skeletal muscle. J Ethnopharmacol. 2010, 127 (1): 32-37. 10.1016\/j.jep.2009.09.055.","journal-title":"J Ethnopharmacol"},{"issue":"1","key":"1515_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jep.2003.12.031","volume":"92","author":"WL Li","year":"2004","unstructured":"Li WL, Zheng HC, Bukuru J, De-Kimpe N: Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus. J Ethnopharmacol. 2004, 92 (1): 1-21. 10.1016\/j.jep.2003.12.031.","journal-title":"J Ethnopharmacol"},{"issue":"11","key":"1515_CR14","doi-asserted-by":"publisher","first-page":"22","DOI":"10.4103\/0973-7847.95854","volume":"6","author":"CH Chan","year":"2012","unstructured":"Chan CH, Ngoh GC, Yusoff R: Brief review on anti diabetic plants: Global distribution, active ingredients, extraction techniques and acting mechanisms. Pharmacogn Rev. 2012, 6 (11): 22-28. 10.4103\/0973-7847.95854.","journal-title":"Pharmacogn Rev"},{"key":"1515_CR15","first-page":"62","volume":"1","author":"P Commission","year":"2010","unstructured":"Commission P: Pharmacopoeia of the People\u2019s Republic of China; Medical Science and Technology Press: Beijing. China. 2010, 1: 62-63.","journal-title":"China"},{"issue":"4","key":"1515_CR16","doi-asserted-by":"publisher","first-page":"3360","DOI":"10.3390\/molecules16043360","volume":"16","author":"WS Pang","year":"2011","unstructured":"Pang WS, Lin SD, Dai QW, Zhang HC, Hu J: Antitussive activity of pseudostellaria heterophylla (Miq.) pax extracts and improvement in lung function via adjustment of multi-cytokine levels. Molecules. 2011, 16 (4): 3360-3370.","journal-title":"Molecules"},{"key":"1515_CR17","first-page":"17","volume":"l8","author":"LZ Xia","year":"2009","unstructured":"Xia LZ, Xu XX, Zhang R: Efects of Pseudostellaria Polysaccharides on Glucose and Lipid Metabolism in Diabetic Rats. China Pharmaceuticals. 2009, l8: 17-18.","journal-title":"China Pharmaceuticals"},{"issue":"5","key":"1515_CR18","first-page":"521","volume":"14","author":"SD Ni","year":"2010","unstructured":"Ni SD, Xia LZ, Xu XX, Zhang R: Efect of pseudostellaria polysaccharides in diabetic mice by alloxan. Anhui Medical and Pharmaceutical. 2010, 14 (5): 521-522.","journal-title":"Anhui Medical and Pharmaceutical"},{"issue":"2","key":"1515_CR19","first-page":"423","volume":"30","author":"JL Xu","year":"2012","unstructured":"Xu JL, Xu AR, Ying JY, Ma WC, Chen YN: Effect of Pseudostellaria Polysaccharides on Glucose and Insulin Metabolism on Diabetic Rats. Chinese Arch Tradit Chinese Medicine. 2012, 30 (2): 423-424.","journal-title":"Chinese Arch Tradit Chinese Medicine"},{"key":"1515_CR20","doi-asserted-by":"publisher","first-page":"173","DOI":"10.2147\/DMSO.S9089","volume":"3","author":"A Badawi","year":"2010","unstructured":"Badawi A, Klip A, Haddad P, Cole DEC, Garcia BB, El-Sohemy A, Karmali M: Type 2 diabetes mellitus and inflammation: Prospects for biomarkers of risk and nutritional intervention. Diabetes, Metab Syndr Obes. 2010, 3: 173-186.","journal-title":"Diabetes, Metab Syndr Obes"},{"key":"1515_CR21","first-page":"603","volume-title":"Experimental Methodology of TCM Pharmacology","author":"YK Li","year":"2006","unstructured":"Li YK, Jin RM, Wang QM: Experimental Methodology of TCM Pharmacology. 2006, Shanghai, China: Shanghai Science and Technology Press, 603-607."},{"issue":"2","key":"1515_CR22","first-page":"819","volume":"3","author":"R Ankur","year":"2012","unstructured":"Ankur R, Shahjad A: Alloxan induced diabetes: mechanisms and effects. Int J Res Pharm Biomed Sci. 2012, 3 (2): 819-823.","journal-title":"Int J Res Pharm Biomed Sci"},{"issue":"4","key":"1515_CR23","first-page":"170","volume":"26","author":"A Duseja","year":"2007","unstructured":"Duseja A, Thumburu KK, Das A, Dhiman RK, Chawla YK, Bhadada S, Bhansali A: Insulin tolerance test is comparable to homeostasis model assessment for insulin resistance in patients with nonalcoholic fatty liver disease. Indian J Gastroenterol. 2007, 26 (4): 170-173.","journal-title":"Indian J Gastroenterol"},{"issue":"10","key":"1515_CR24","doi-asserted-by":"publisher","first-page":"4065","DOI":"10.1210\/jc.2008-0396","volume":"93","author":"BS Marianne","year":"2008","unstructured":"Marianne BS, Jeffrey T, G\u00e9raldine P, Lorella M, Jan AE, Julie KC, Francois P, Philippe AH, Gordon CW, Marc YD: Increased Interleukin (IL)-1\u03b2 Messenger Ribonucleic Acid Expression in \u03b2-Cells of Individuals with Type 2 Diabetes and Regulation of IL-1\u03b2 in Human Islets by Glucose and Autostimulation. Clin Endocrinol Metab. 2008, 93 (10): 4065-4074. 10.1210\/jc.2008-0396.","journal-title":"Clin Endocrinol Metab"},{"key":"1515_CR25","doi-asserted-by":"publisher","first-page":"941","DOI":"10.1038\/90984","volume":"7","author":"T Yamauchi","year":"2001","unstructured":"Yamauchi T, Kamon J, Waki H, Terauchi Y, Kubota N, Hara K, Mori Y, Ide T, Murakami K, Tsuboyama-Kasaoka N, Ezaki O, Akanuma Y, Gavrilova O, Vinson C, Reitman ML, Kagechika H, Shudo K, Yoda M, Nakano Y, Tobe K, Nagai R, Kimura S, Tomita M, Froguel P, Kadowaki T: The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med. 2001, 7: 941-946. 10.1038\/90984.","journal-title":"Nat Med"},{"issue":"2","key":"1515_CR26","first-page":"209","volume":"1","author":"S Ravipati","year":"2011","unstructured":"Ravipati S, Rajkuma B: Role of Leptin in Diabetes Mellitus. Indian J Fundam Appl Life Sci. 2011, 1 (2): 209-214.","journal-title":"Indian J Fundam Appl Life Sci"}],"container-title":["BMC Complementary and Alternative Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1472-6882-13-267\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1472-6882-13-267.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1472-6882-13-267","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1472-6882-13-267.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,23]],"date-time":"2019-01-23T02:03:46Z","timestamp":1548209026000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmccomplementalternmed.biomedcentral.com\/articles\/10.1186\/1472-6882-13-267"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,16]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["1515"],"URL":"https:\/\/doi.org\/10.1186\/1472-6882-13-267","relation":{},"ISSN":["1472-6882"],"issn-type":[{"value":"1472-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,16]]},"article-number":"267"}}