{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T04:49:22Z","timestamp":1761540562558},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2004,10,12]],"date-time":"2004-10-12T00:00:00Z","timestamp":1097539200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Med Inform Decis Mak"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                        <jats:title>Background<\/jats:title>\n                        <jats:p>Design and test the reliability of a web-based system for multicenter, real-time collection of data in the emergency department (ED), under waiver of authorization, in compliance with HIPAA.<\/jats:p>\n                     <\/jats:sec><jats:sec>\n                        <jats:title>Methods<\/jats:title>\n                        <jats:p>This was a phase I, two-hospital study of patients undergoing evaluation for possible pulmonary embolism. Data were collected by on-duty clinicians on an HTML data collection form (prospective e-form), populated using either a personal digital assistant (PDA) or personal computer (PC). Data forms were uploaded to a central, offsite server using secure socket protocol transfer. Each form was assigned a unique identifier, and all PHI data were encrypted, but were password-accessible by authorized research personnel to complete a follow-up e-form.<\/jats:p>\n                     <\/jats:sec><jats:sec>\n                        <jats:title>Results<\/jats:title>\n                        <jats:p>From April 15, 2003-April 15 2004, 1022 prospective e-forms and 605 follow-up e-forms were uploaded. Complexities of PDA use compelled clinicians to use PCs in the ED for data entry for most forms. No data were lost and server log query revealed no unauthorized entry. Prospectively obtained PHI data, encrypted upon server upload, were successfully decrypted using password-protected access to allow follow-up without difficulty in 605 cases. Non-PHI data from prospective and follow-up forms were available to the study investigators via standard file transfer protocol.<\/jats:p>\n                     <\/jats:sec><jats:sec>\n                        <jats:title>Conclusions<\/jats:title>\n                        <jats:p>Data can be accurately collected from on-duty clinicians in the ED using real-time, PC-Internet data entry in compliance with the Privacy Rule. Deidentification-reidentification of PHI was successfully accomplished by a password-protected encryption-deencryption mechanism to permit follow-up by approved research personnel.<\/jats:p>\n                     <\/jats:sec>","DOI":"10.1186\/1472-6947-4-17","type":"journal-article","created":{"date-parts":[[2004,10,15]],"date-time":"2004-10-15T06:23:45Z","timestamp":1097821425000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Prospective study of clinician-entered research data in the Emergency Department using an Internet-based system after the HIPAA Privacy Rule"],"prefix":"10.1186","volume":"4","author":[{"given":"Jeffrey A","family":"Kline","sequence":"first","affiliation":[]},{"given":"Charles L","family":"Johnson","sequence":"additional","affiliation":[]},{"given":"William B","family":"Webb","sequence":"additional","affiliation":[]},{"given":"Michael S","family":"Runyon","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2004,10,12]]},"reference":[{"key":"45_CR1","unstructured":"Services Department of Health and Human: 2004, Hyattsville, MD, 45 CFR parts 160 and 164: 824565-824566. Standards for Privacy of Individually Identifiable Health Information, vol 65 no 250"},{"key":"45_CR2","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1056\/NEJM200201173460320","volume":"346","author":"GJ Annas","year":"2002","unstructured":"Annas GJ: Medical privacy and medical research--judging the new federal regulations.[see comment]. New England Journal of Medicine. 2002, 346: 216-220. 10.1056\/NEJM200201173460320.","journal-title":"New England Journal of Medicine"},{"key":"45_CR3","doi-asserted-by":"publisher","first-page":"912","DOI":"10.1161\/01.CIR.0000080642.35380.50","volume":"108","author":"J Kulynych","year":"2003","unstructured":"Kulynych J, Korn D: The new HIPAA (Health Insurance Portability and Accountability Act of 1996) Medical Privacy Rule: help or hindrance for clinical research?[see comment]. [Review] [7 refs]. Circulation. 2003, 108: 912-914. 10.1161\/01.CIR.0000080642.35380.50.","journal-title":"Circulation"},{"key":"45_CR4","doi-asserted-by":"publisher","first-page":"1414","DOI":"10.1056\/NEJMsa031697","volume":"350","author":"JV Tu","year":"2004","unstructured":"Tu JV, Willison DJ, Silver SL, Fang J, Richards JA, Laupacis A, Kapral MK: Impracticability of rnformed consent in the registry of the Canadian stroke network. N Eng J Med. 2004, 350: 1414-1421. 10.1056\/NEJMsa031697.","journal-title":"N Eng J Med"},{"key":"45_CR5","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1016\/j.annemergmed.2004.03.018","volume":"44","author":"JA Kline","year":"2004","unstructured":"Kline JA, Webb WB, Jones AE, Hernandez J: Impact of a Rapid Rule-Out Protocol for Pulmonary Embolism on the Rate of Screening, Missed Cases, and Pulmonary Vascular Imaging in an Urban U.S. Emergency Department. Annals Emerg Med. 2004, 44: 490-502.","journal-title":"Annals Emerg Med"},{"key":"45_CR6","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1007\/s00464-001-8400-7","volume":"16","author":"DL Fowler","year":"2002","unstructured":"Fowler DL, Hogle NJ, Martini F, Roh MS: The use of a personal digital assistant for wireless entry of data into a database via the Internet. Surgical Endoscopy. 2002, 16: 221-223. 10.1007\/s00464-001-8400-7.","journal-title":"Surgical Endoscopy"},{"key":"45_CR7","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1016\/S0300-2896(02)75256-3","volume":"38","author":"M Miravitlles","year":"2002","unstructured":"Miravitlles M, Llor C, Naberan K, Cots JM, EFEMAP. en representacion del estudio: [Use of the Internet in a multicenter study of chronic obstructive pulmonary disease in primary care. Pilot phase of the EFEMAP study]. [Spanish]. Archivos de Bronconeumologia. 2002, 38: 427-430.","journal-title":"Archivos de Bronconeumologia"},{"key":"45_CR8","first-page":"40","volume-title":"AMIA Annu Sympo Proc","author":"YC Lu","year":"2003","unstructured":"Lu YC, Lee JK, Xiao Y, Sears A, Jacko JA, Chambers K: Why don't physicians use their personal digital assistants?. AMIA Annu Sympo Proc. 2003, 40-45."},{"key":"45_CR9","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1089\/153056201300093976","volume":"7","author":"J Kuchenbecker","year":"2001","unstructured":"Kuchenbecker J, Dick HB, Schmitz K, Behrens-Baumann W: Use of internet technologies for data acquisition in large clinical trials. Telemedicine Journal & E-Health. 2001, 7: 73-76. 10.1089\/153056201300093976.","journal-title":"Telemedicine Journal & E-Health"},{"key":"45_CR10","doi-asserted-by":"publisher","first-page":"1228","DOI":"10.1016\/S0735-1097(98)00423-9","volume":"32","author":"CJ Pepine","year":"1998","unstructured":"Pepine CJ, Handberg-Thurmond E, Marks RG, Conlon M, Cooper-DeHoff R, Volkers P, Zellig P: Rationale and design of the International Verapamil SR\/Trandolapril Study (INVEST): an Internet-based randomized trial in coronary artery disease patients with hypertension. Journal of the American College of Cardiology. 1998, 32: 1228-1237. 10.1016\/S0735-1097(98)00423-9.","journal-title":"Journal of the American College of Cardiology"},{"key":"45_CR11","first-page":"57","volume":"43 Pt A","author":"E Keim","year":"1997","unstructured":"Keim E, Sippel H, Eich HP, Ohmann C: Collection of data in clinical studies via Internet. Stud Health Technol & Inform. 1997, 43 Pt A: 57-60.","journal-title":"Stud Health Technol & Inform"},{"key":"45_CR12","first-page":"182","volume":"103","author":"J Turpin","year":"2003","unstructured":"Turpin J, Rose R, Larsen B: An adaptable, transportable web-based data acquisition platform for clinical and survey-based research. Journal of the American Osteopathic Association. 2003, 103: 182-186.","journal-title":"Journal of the American Osteopathic Association"}],"container-title":["BMC Medical Informatics and Decision Making"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1472-6947-4-17.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1472-6947-4-17\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1472-6947-4-17","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1472-6947-4-17.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T13:18:52Z","timestamp":1728307132000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcmedinformdecismak.biomedcentral.com\/articles\/10.1186\/1472-6947-4-17"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,10,12]]},"references-count":12,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2004,12]]}},"alternative-id":["45"],"URL":"https:\/\/doi.org\/10.1186\/1472-6947-4-17","relation":{},"ISSN":["1472-6947"],"issn-type":[{"type":"electronic","value":"1472-6947"}],"subject":[],"published":{"date-parts":[[2004,10,12]]},"assertion":[{"value":"22 June 2004","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 October 2004","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 October 2004","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"17"}}